메뉴 건너뛰기




Volumn 57, Issue 5, 2013, Pages 1838-1846

Molecular subtype and response to dasatinib, an Src/Abl small molecule kinase inhibitor, in hepatocellular carcinoma cell lines in vitro

Author keywords

[No Author keywords available]

Indexed keywords

DASATINIB; RNA;

EID: 84876734918     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26223     Document Type: Article
Times cited : (42)

References (28)
  • 1
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999; 340: 745-750.
    • (1999) N Engl J Med , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 2
    • 63049133092 scopus 로고    scopus 로고
    • Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    • Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol 2009; 27: 1485-1491.
    • (2009) J Clin Oncol , vol.27 , pp. 1485-1491
    • Altekruse, S.F.1    McGlynn, K.A.2    Reichman, M.E.3
  • 4
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, Kim JS, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009; 10: 25-34.
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3    Tsao, C.J.4    Qin, S.5    Kim, J.S.6
  • 5
    • 74549124210 scopus 로고    scopus 로고
    • Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now?
    • Finn RS. Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now? Clin Cancer Res 2010; 16: 390-397.
    • (2010) Clin Cancer Res , vol.16 , pp. 390-397
    • Finn, R.S.1
  • 6
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 7
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 8
    • 33645742425 scopus 로고    scopus 로고
    • A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
    • Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006; 12: 410-416.
    • (2006) Nat Med , vol.12 , pp. 410-416
    • Lee, J.S.1    Heo, J.2    Libbrecht, L.3    Chu, I.S.4    Kaposi-Novak, P.5    Calvisi, D.F.6
  • 9
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. HEPATOLOGY 2007; 45: 42-52.
    • (2007) HEPATOLOGY , vol.45 , pp. 42-52
    • Boyault, S.1    Rickman, D.S.2    de Reynies, A.3    Balabaud, C.4    Rebouissou, S.5    Jeannot, E.6
  • 10
    • 42249087302 scopus 로고    scopus 로고
    • Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma
    • Woo HG, Park ES, Cheon JH, Kim JH, Lee JS, Park BJ, et al. Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma. Clin Cancer Res 2008; 14: 2056-2064.
    • (2008) Clin Cancer Res , vol.14 , pp. 2056-2064
    • Woo, H.G.1    Park, E.S.2    Cheon, J.H.3    Kim, J.H.4    Lee, J.S.5    Park, B.J.6
  • 11
    • 40449099255 scopus 로고    scopus 로고
    • EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
    • Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H, et al. EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res 2008; 68: 1451-1461.
    • (2008) Cancer Res , vol.68 , pp. 1451-1461
    • Yamashita, T.1    Forgues, M.2    Wang, W.3    Kim, J.W.4    Ye, Q.5    Jia, H.6
  • 12
    • 53049086329 scopus 로고    scopus 로고
    • Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
    • Chiang DY, Villanueva A, Hoshida Y, Peix J, Newell P, Minguez B, et al. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res 2008; 68: 6779-6788.
    • (2008) Cancer Res , vol.68 , pp. 6779-6788
    • Chiang, D.Y.1    Villanueva, A.2    Hoshida, Y.3    Peix, J.4    Newell, P.5    Minguez, B.6
  • 14
    • 34548701082 scopus 로고    scopus 로고
    • Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro
    • Finn RS, Dering J, Ginther C, Wilson CA, Glaspy P, Tchekmedyian N, et al. Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro. Breast Cancer Res Treat 2007; 105: 319-326.
    • (2007) Breast Cancer Res Treat , vol.105 , pp. 319-326
    • Finn, R.S.1    Dering, J.2    Ginther, C.3    Wilson, C.A.4    Glaspy, P.5    Tchekmedyian, N.6
  • 15
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10: 515-527.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 16
    • 80455173400 scopus 로고    scopus 로고
    • Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study
    • Finn RS, Bengala C, Ibrahim N, Roche H, Sparano J, Strauss LC, et al. Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study. Clin Cancer Res 2011; 17: 6905-6913.
    • (2011) Clin Cancer Res , vol.17 , pp. 6905-6913
    • Finn, R.S.1    Bengala, C.2    Ibrahim, N.3    Roche, H.4    Sparano, J.5    Strauss, L.C.6
  • 17
    • 76049104235 scopus 로고    scopus 로고
    • PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro
    • Finn RS, Dering J, Conklin D, Kalous O, Cohen DJ, Desai AJ, et al. PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro. Breast Cancer Res 2009; 11: R77.
    • (2009) Breast Cancer Res , vol.11
    • Finn, R.S.1    Dering, J.2    Conklin, D.3    Kalous, O.4    Cohen, D.J.5    Desai, A.J.6
  • 18
    • 19944428353 scopus 로고    scopus 로고
    • Discovery of N-(2-chloro-6-methyl-phenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
    • Lombardo LJ, Lee FY, Chen P, Norris D, Barrish JC, Behnia K, et al. Discovery of N-(2-chloro-6-methyl-phenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J Med Chem 2004; 47: 6658-6661.
    • (2004) J Med Chem , vol.47 , pp. 6658-6661
    • Lombardo, L.J.1    Lee, F.Y.2    Chen, P.3    Norris, D.4    Barrish, J.C.5    Behnia, K.6
  • 19
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for SRC
    • Yeatman TJ. A renaissance for SRC. Nat Rev Cancer 2004; 4: 470-480.
    • (2004) Nat Rev Cancer , vol.4 , pp. 470-480
    • Yeatman, T.J.1
  • 20
  • 21
    • 0034939717 scopus 로고    scopus 로고
    • Activation of c-Src gene product in hepatocellular carcinoma is highly correlated with the indices of early stage phenotype
    • Ito Y, Kawakatsu H, Takeda T, Sakon M, Nagano H, Sakai T, et al. Activation of c-Src gene product in hepatocellular carcinoma is highly correlated with the indices of early stage phenotype. J Hepatol 2001; 35: 68-73.
    • (2001) J Hepatol , vol.35 , pp. 68-73
    • Ito, Y.1    Kawakatsu, H.2    Takeda, T.3    Sakon, M.4    Nagano, H.5    Sakai, T.6
  • 22
    • 67349209558 scopus 로고    scopus 로고
    • Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro
    • Lau GM, Lau GM, Yu GL, Gelman IH, Gutowski A, Hangauer D, et al. Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro. Dig Dis Sci 2009; 54: 1465-1474.
    • (2009) Dig Dis Sci , vol.54 , pp. 1465-1474
    • Lau, G.M.1    Lau, G.M.2    Yu, G.L.3    Gelman, I.H.4    Gutowski, A.5    Hangauer, D.6
  • 23
    • 0037076272 scopus 로고    scopus 로고
    • Diagnosis of multiple cancer types by shrunken centroids of gene expression
    • Tibshirani R, Hastie T, Narasimhan B, Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A 2002; 99: 6567-6572.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6567-6572
    • Tibshirani, R.1    Hastie, T.2    Narasimhan, B.3    Chu, G.4
  • 24
    • 4544273428 scopus 로고    scopus 로고
    • Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
    • Lee JS, Chu IS, Heo J, Calvisi DF, Sun Z, Roskams T, Durnez A, et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. HEPATOLOGY 2004; 40: 667-676.
    • (2004) HEPATOLOGY , vol.40 , pp. 667-676
    • Lee, J.S.1    Chu, I.S.2    Heo, J.3    Calvisi, D.F.4    Sun, Z.5    Roskams, T.6    Durnez, A.7
  • 25
    • 33947225176 scopus 로고    scopus 로고
    • Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection
    • Huang F, Reeves K, Han X, Fairchild C, Platero S, Wong TW, et al. Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection. Cancer Res 2007; 67: 2226-2238.
    • (2007) Cancer Res , vol.67 , pp. 2226-2238
    • Huang, F.1    Reeves, K.2    Han, X.3    Fairchild, C.4    Platero, S.5    Wong, T.W.6
  • 26
    • 0036234628 scopus 로고    scopus 로고
    • Functional and genomic implications of global gene expression profiles in cell lines from human hepatocellular cancer
    • Lee JS, Thorgeirsson SS. Functional and genomic implications of global gene expression profiles in cell lines from human hepatocellular cancer. HEPATOLOGY 2002; 35: 1134-1143.
    • (2002) HEPATOLOGY , vol.35 , pp. 1134-1143
    • Lee, J.S.1    Thorgeirsson, S.S.2
  • 28
    • 77956042544 scopus 로고    scopus 로고
    • SRC: a century of science brought to the clinic
    • Aleshin A, Finn RS. SRC: a century of science brought to the clinic. Neoplasia 2010; 12: 599-607.
    • (2010) Neoplasia , vol.12 , pp. 599-607
    • Aleshin, A.1    Finn, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.