Hypersensitivity reactions to fluoroquinolones: Analysis of the factors involved

Clinical and Experimental Allergy

Volumn 43, Issue 5, 2013, Pages 560-567

  Blanca Lopez N ^a   Ariza, A ^b   Dona I ^b   Mayorga, C ^b   Montanez M I ^b   Garcia Campos, J ^b   Gomez, F ^b   Rondon C ^b   Blanca, M ^b   Torres, M J ^b  

^a HOSPITAL UNIVERSITARIO INFANTA LEONOR   (Spain)

^b HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

Author keywords

Allergy; Anaphylaxis; Fluoroquinolones; IgE; Penicillin

Indexed keywords

BETA LACTAM; CIPROFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; NORFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADULT; ANAPHYLAXIS; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG HYPERSENSITIVITY; FEMALE; GENDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROVOCATION TEST; RASH; RETROSPECTIVE STUDY; TIME; URTICARIA;

ADULT; ANTI-BACTERIAL AGENTS; BASOPHILS; BRONCHIAL PROVOCATION TESTS; DRUG HYPERSENSITIVITY; FEMALE; FLUOROQUINOLONES; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84876723494     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12099     Document Type: Article

References (38)

1. Ball P. Quinolone generations: natural history or natural selection? J Antimicrob Chemother 2000; 46:17-24.
2. Doña I, Blanca-Lopez N, Torres MJ et al. Drug hypersensitivity reactions: patterns of responses, drug involved and temporal variation in a large series of patients evaluated. J Investig Allergol Clin Immunol 2012; 22:363-71.
3. Sachs B, Riegel S, Seebeck J et al. Fluoroquinolone-associated anaphylaxis in spontaneous adverse drug reaction reports in Germany: differences in reporting rates between individual fluoroquinolones and occurrence after first-ever use. Drug Saf 2006; 29:1087-100.
4. Aranda A, Mayorga C, Ariza A et al. In vitro evaluation of IgE-mediated hypersensitivity reactions to quinolones. Allergy 2011; 66:247-54.
5. Seitz CS, Bröcker EB, Trautmann A. Diagnostic testing in suspected fluoroquinolone hypersensitivity. Clin Exp Allergy 2009; 39:1738-45.
6. Manfredi M, Severino M, Testi S et al. Detection of specific IgE to quinolones. J Allergy Clin Immunol 2004; 113:155-60.
7. Venturini M, Lobera T, del PG, Blasco A, Gonzalez I. In vivo diagnostic tests in adverse reactions to quinolones. J Investig Allergol Clin Immunol 2007; 17:393-8.
8. Blanca-López N, Andreu I, Torres MJ. Hypersensitivity reactions to quinolones. Curr Opin Allergy Clin Immunol 2011; 11:285-91.
9. Schmid DA, Depta JP, Pichler WJ. T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. Clin Exp Allergy 2006; 36:59-69.
10. Fernandez-Rivas M. Fixed drug eruption (FDE) caused by norfloxacin. Allergy 1997; 52:477-8.
11. Alonso MD, Martín JA, Quirce S, Dávila I, Lezaun A, Sanchez CM. Fixed eruption caused by ciprofloxacin with cross-sensitivity to norfloxacin. Allergy 1993; 48:296-7.
12. García RR, Galindo BP, Feo BF et al. Chronic desensitization to quinolones in fixed drug eruption. J Investig Allergol Clin Immunol 2011; 21:76-7.
13. Davila G, Ruiz-Hornillos J, Rojas P, De CF, Zubeldia JM. Toxic epidermal necrolysis induced by levofloxacin. Ann Allergy Asthma Immunol 2009; 102:441-2.
14. Yoon SY, Bae YJ, Cho YS, Moon HB, Kim TB. Toxic epidermal necrolysis induced by ofloxacin. Acta Derm Venereol 2010; 90:550-1.
15. Islam AF, Rahman MS. Levofloxacin-induced fatal toxic epidermal necrolysis. Ann Pharmacother 2005; 39:1136-7.
16. Gonzalez I, Lobera T, Blasco A, del PM. Immediate hypersensitivity to quinolones: moxifloxacin cross-reactivity. J Investig Allergol Clin Immunol 2005; 15:146-9.
17. Nuñez OV, Limeres PJ, Carmona IT, Diz DP. Efficacy of fluoroquinolones against pathogenic oral bacteria. Mini Rev Med Chem 2009; 9:1147-58.
18. Carlucci G. Analysis of fluoroquinolones in biological fluids by high-performance liquid chromatography. J Chromathogr A 1998; 812:343-67.
19. Hooper DC, Rubinstein E, eds. Quinolone antimicrobial agents, 3rd Edn. Washington DC: American Society for Microbiology, ASM Press, 2003.
20. Andreu I, Mayorga C, Miranda MA. Metabolomics in Drug Intolerance. Curr Drug Metab 2009; 10:947-55.
21. Sullivan TJ, Remedios C, Ong MD, Gillian LK. Studies of the multiple drug allergy syndrome. J Allergy Clin Immunol 1989; 83:270.
22. Khoury L, Warrington RJ. The multiple allergy syndrome: a matched control retrospective study in patients allergic to penicillin. J Allergy Clin Immunol 1996; 98:462-4.
23. Strom BL, Schinnar R, Apter AJ et al. Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics. N Engl J Med 2003; 349:1628-35.
24. Pichler WJ, Daubner B, Kawabata T. Drug hypersensitivity: flare-up reactions, cross-reactivity and multiple drug hypersensitivity. J Dermatol 2011; 38:216-21.
25. González-Mancebo E, Fernández-Rivas M. Immediate hypersensitivity to levofloxacin diagnosed through skin prick test. Ann Pharmacother 2004; 38:354.
26. Sánchez-Morillas L, Rojas P-EP, Reaño-Martos M, Laguna-Martinez JJ, Gomez-Tembleque P. Systemic anaphylaxis caused by moxifloxacin. Allergol Immunopathol 2010; 38:226-7.
27. Lobera T, Audicana MT, Alarcon E, Longo N, Navarro B, Muñoz D. Allergy to quinolones: low cross reactivity to levofloxacin. J Investig Allergol Clin Immunol 2010; 20:607-11.
28. Scherer K, Bircher AJ. Hypersensitivity reactions to fluoroquinolones. Curr Allergy Asthma Rep 2005; 5:15-21.
29. Empedrad R, Darter AL, Earl HS, Gruchalla RS. Nonirritating intradermal skin test concentrations for commonly prescribed antibiotics. J Allergy Clin Immunol 2003; 112:629-30.
30. Ben SB, Berard F, Bienvenu J, Nicolas JF, Rozieres A. Usefulness of basophil activation tests for the diagnosis of IgE-mediated allergy to quinolones. Allergy 2010; 65:535-6.
31. Rouzaire P, Nosbaum A, Denis L et al. Negativity of the basophil activation test in quinolone hypersensitivity: a breakthrough for provocation test decision-making. Int Arch Allergy Immunol 2012; 157:299-302.
32. Demoly P, Kropf R, Bircher A, Pichler WJ. Drug hypersensitivity: questionnaire. EAACI interest group on drug hypersensitivity. Allergy 1999; 54:999-1003.
33. Sampson HA, Muñoz-Furlong A, Campbell RL et al. Second symposium on the definition and management of anaphylaxis: summary report-Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol 2006; 117:391-7.
34. Aberer W, Bircher A, Romano A et al. Drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations. Allergy 2003; 58:854-63.
35. Lazaro E, de Abajo F. Uso de antibióticos en España. Spanish Agency for drugs, Pharmaco-epidemiology Division (AEMPS) Publication 2010; 1-9.
36. Padial A, Antunez C, Blanca-Lopez N et al. Non-immediate reactions to beta-lactams: diagnostic value of skin testing and drug provocation test. Clin Exp Allergy 2008; 38:822-8.
37. Blanca-Lopez N, Zapatero L, Alonso E et al. Skin testing and drug provocation tests in the diagnosis of non immediate reactions to aminopenicillins in children. Allergy 2009; 64:229-33.
38. Caubet JC, Kaiser L, Lemaître B, Fellay B, Gervaix A, Eigenmann PA. The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge. J Allergy Clin Immunol 2011; 127:218-22.