메뉴 건너뛰기




Volumn 45, Issue 5, 2013, Pages 408-413

The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib

Author keywords

Advanced liver cancer; Baseline factors; Prognosis; Targeted therapy

Indexed keywords

SORAFENIB;

EID: 84876716745     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2012.10.010     Document Type: Article
Times cited : (27)

References (41)
  • 2
    • 77954333413 scopus 로고    scopus 로고
    • Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection
    • Alazawi W., Cunningham M., Dearden J., et al. Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection. Alimentary Pharmacology and Therapeutics 2010, 32(3):344-355.
    • (2010) Alimentary Pharmacology and Therapeutics , vol.32 , Issue.3 , pp. 344-355
    • Alazawi, W.1    Cunningham, M.2    Dearden, J.3
  • 3
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Forner A., Llovet J.M., Bruix J. Hepatocellular carcinoma. Lancet 2012, 379(9822):1245-1255.
    • (2012) Lancet , vol.379 , Issue.9822 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 5
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
    • Cheng A.L., Kang Y.K., Chen Z., et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncology 2009, 10(1):25-34.
    • (2009) Lancet Oncology , vol.10 , Issue.1 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3
  • 6
    • 79952231921 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma: an update
    • Bruix J., Sherman M. Management of hepatocellular carcinoma: an update. Hepatology 2011, 53(3):1020-1022.
    • (2011) Hepatology , vol.53 , Issue.3 , pp. 1020-1022
    • Bruix, J.1    Sherman, M.2
  • 7
    • 84858658381 scopus 로고    scopus 로고
    • EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma
    • EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. Journal of Hepatology 2012, 56(4):908-943.
    • (2012) Journal of Hepatology , vol.56 , Issue.4 , pp. 908-943
  • 8
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • Wilhelm S.M., Carter C., Tang L., et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Research 2004, 64(19):7099-7109.
    • (2004) Cancer Research , vol.64 , Issue.19 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 9
    • 77953776656 scopus 로고    scopus 로고
    • Future perspectives in hepatocellular carcinoma
    • Worns M.A., Galle P.R. Future perspectives in hepatocellular carcinoma. Digestive and Liver Disease 2010, 42(Suppl 3):S302-S309.
    • (2010) Digestive and Liver Disease , vol.42 , Issue.SUPPL 3
    • Worns, M.A.1    Galle, P.R.2
  • 10
    • 77951490498 scopus 로고    scopus 로고
    • Novel inhibitors in development for hepatocellular carcinoma
    • Worns M.A., Galle P.R. Novel inhibitors in development for hepatocellular carcinoma. Expert Opinion on Investigational Drugs 2010, 19(5):615-629.
    • (2010) Expert Opinion on Investigational Drugs , vol.19 , Issue.5 , pp. 615-629
    • Worns, M.A.1    Galle, P.R.2
  • 11
    • 84862776817 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: Subset analyses of the phase III Sorafenib Asia-Pacific trial
    • Cheng A.L., Guan Z., Chen Z., et al. Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: Subset analyses of the phase III Sorafenib Asia-Pacific trial. European Journal of Cancer 2012, 48(10):1452-1465.
    • (2012) European Journal of Cancer , vol.48 , Issue.10 , pp. 1452-1465
    • Cheng, A.L.1    Guan, Z.2    Chen, Z.3
  • 12
    • 84859726758 scopus 로고    scopus 로고
    • Relationship between baseline hepatic status and outcome, and effect of sorafenib on liver function: SHARP trial subanalyses
    • Raoul J.L., Bruix J., Greten T.F., et al. Relationship between baseline hepatic status and outcome, and effect of sorafenib on liver function: SHARP trial subanalyses. Journal of Hepatology 2012, 56(5):1080-1088.
    • (2012) Journal of Hepatology , vol.56 , Issue.5 , pp. 1080-1088
    • Raoul, J.L.1    Bruix, J.2    Greten, T.F.3
  • 13
    • 84866391058 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial
    • Bruix J., Raoul J.L., Sherman M., et al. Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial. Journal of Hepatology 2012, 57(4):821-829.
    • (2012) Journal of Hepatology , vol.57 , Issue.4 , pp. 821-829
    • Bruix, J.1    Raoul, J.L.2    Sherman, M.3
  • 14
    • 59449089100 scopus 로고    scopus 로고
    • Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response
    • Yau T., Chan P., Ng K.K., et al. Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response. Cancer 2009, 115(2):428-436.
    • (2009) Cancer , vol.115 , Issue.2 , pp. 428-436
    • Yau, T.1    Chan, P.2    Ng, K.K.3
  • 15
    • 67651095716 scopus 로고    scopus 로고
    • Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis
    • Worns M.A., Weinmann A., Pfingst K., et al. Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis. Journal of Clinical Gastroenterology 2009, 43(5):489-495.
    • (2009) Journal of Clinical Gastroenterology , vol.43 , Issue.5 , pp. 489-495
    • Worns, M.A.1    Weinmann, A.2    Pfingst, K.3
  • 16
    • 61449256583 scopus 로고    scopus 로고
    • Sorafenib in unresectable hepatocellular carcinoma from mild to advanced stage liver cirrhosis
    • Pinter M., Sieghart W., Graziadei I., et al. Sorafenib in unresectable hepatocellular carcinoma from mild to advanced stage liver cirrhosis. Oncologist 2009, 14(1):70-76.
    • (2009) Oncologist , vol.14 , Issue.1 , pp. 70-76
    • Pinter, M.1    Sieghart, W.2    Graziadei, I.3
  • 17
    • 78349275393 scopus 로고    scopus 로고
    • Tolerance and outcome of patients with unresectable hepatocellular carcinoma treated with sorafenib
    • Ozenne V., Paradis V., Pernot S., et al. Tolerance and outcome of patients with unresectable hepatocellular carcinoma treated with sorafenib. European Journal of Gastroenterology & Hepatology 2010, 22(9):1106-1110.
    • (2010) European Journal of Gastroenterology & Hepatology , vol.22 , Issue.9 , pp. 1106-1110
    • Ozenne, V.1    Paradis, V.2    Pernot, S.3
  • 18
    • 80055017402 scopus 로고    scopus 로고
    • Safety and efficacy of sorafenib in hepatocellular carcinoma: the impact of the Child-Pugh score
    • Hollebecque A., Cattan S., Romano O., et al. Safety and efficacy of sorafenib in hepatocellular carcinoma: the impact of the Child-Pugh score. Alimentary Pharmacology and Therapeutics 2011, 34(10):1193-1201.
    • (2011) Alimentary Pharmacology and Therapeutics , vol.34 , Issue.10 , pp. 1193-1201
    • Hollebecque, A.1    Cattan, S.2    Romano, O.3
  • 19
    • 80955142670 scopus 로고    scopus 로고
    • A single center experience of sorafenib in advanced hepatocellular carcinoma patients: evaluation of prognostic factors
    • Song T., Zhang W., Wu Q., et al. A single center experience of sorafenib in advanced hepatocellular carcinoma patients: evaluation of prognostic factors. European Journal of Gastroenterology and Hepatology 2011, 23(12):1233-1238.
    • (2011) European Journal of Gastroenterology and Hepatology , vol.23 , Issue.12 , pp. 1233-1238
    • Song, T.1    Zhang, W.2    Wu, Q.3
  • 20
    • 79959421984 scopus 로고    scopus 로고
    • Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective comparison with previously known prognostic models
    • Baek K.K., Kim J.H., Uhm J.E., et al. Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective comparison with previously known prognostic models. Oncology 2011, 80(3-4):167-174.
    • (2011) Oncology , vol.80 , Issue.3-4 , pp. 167-174
    • Baek, K.K.1    Kim, J.H.2    Uhm, J.E.3
  • 21
    • 82455192245 scopus 로고    scopus 로고
    • Sorafenib for hepatocellular carcinoma according to Child-Pugh class of liver function
    • Kim J.E., Ryoo B.Y., Ryu M.H., et al. Sorafenib for hepatocellular carcinoma according to Child-Pugh class of liver function. Cancer Chemotherapy and Pharmacology 2011, 68(5):1285-1290.
    • (2011) Cancer Chemotherapy and Pharmacology , vol.68 , Issue.5 , pp. 1285-1290
    • Kim, J.E.1    Ryoo, B.Y.2    Ryu, M.H.3
  • 22
    • 82355192537 scopus 로고    scopus 로고
    • Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of its Treatment with Sorafenib (GIDEON) second interim analysis in more than 1500 patients: Clinical findings in patients with liver dysfunction
    • [abstr 4001]
    • Marrero J.A., Lencioni R., Kudo M., et al. Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of its Treatment with Sorafenib (GIDEON) second interim analysis in more than 1500 patients: Clinical findings in patients with liver dysfunction. Journal of Clinical Oncology 2011, 29(suppl). [abstr 4001].
    • (2011) Journal of Clinical Oncology , vol.29 , Issue.SUPPL.
    • Marrero, J.A.1    Lencioni, R.2    Kudo, M.3
  • 23
    • 80053217954 scopus 로고    scopus 로고
    • Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib
    • Pinter M., Sieghart W., Hucke F., et al. Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib. Alimentary Pharmacology and Therapeutics 2011, 34(8):949-959.
    • (2011) Alimentary Pharmacology and Therapeutics , vol.34 , Issue.8 , pp. 949-959
    • Pinter, M.1    Sieghart, W.2    Hucke, F.3
  • 24
    • 84867871965 scopus 로고    scopus 로고
    • The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: a retrospective analysis of efficacy, safety, and survival benefits
    • Chiu J., Tang Y.F., Yao T.J., et al. The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: a retrospective analysis of efficacy, safety, and survival benefits. Cancer 2012.
    • (2012) Cancer
    • Chiu, J.1    Tang, Y.F.2    Yao, T.J.3
  • 25
    • 67651115584 scopus 로고    scopus 로고
    • Target therapy for hepatocellular carcinoma: is sorafenib for everybody?
    • Daniele B., Di Maio M. Target therapy for hepatocellular carcinoma: is sorafenib for everybody?. Journal of Clinical Gastroenterology 2009, 43(5):389-390.
    • (2009) Journal of Clinical Gastroenterology , vol.43 , Issue.5 , pp. 389-390
    • Daniele, B.1    Di Maio, M.2
  • 26
    • 70450187411 scopus 로고    scopus 로고
    • Targeted therapies: role of sorafenib in HCC patients with compromised liver function
    • Di Maio M., Daniele B., Perrone F. Targeted therapies: role of sorafenib in HCC patients with compromised liver function. Nature Reviews Clinical Oncology 2009, 6(9):505-506.
    • (2009) Nature Reviews Clinical Oncology , vol.6 , Issue.9 , pp. 505-506
    • Di Maio, M.1    Daniele, B.2    Perrone, F.3
  • 27
    • 80053041858 scopus 로고    scopus 로고
    • Safety and efficacy of sorafenib in patients with hepatocellular carcinoma (HCC) and Child-Pugh A versus B cirrhosis
    • Abou-Alfa G.K., Amadori D., Santoro A., et al. Safety and efficacy of sorafenib in patients with hepatocellular carcinoma (HCC) and Child-Pugh A versus B cirrhosis. Gastrointestinal Cancer Research 2011, 4(2):40-44.
    • (2011) Gastrointestinal Cancer Research , vol.4 , Issue.2 , pp. 40-44
    • Abou-Alfa, G.K.1    Amadori, D.2    Santoro, A.3
  • 28
    • 84862737988 scopus 로고    scopus 로고
    • First interim analysis of the GIDEON (Global Investigation of therapeutic DEcisions in hepatocellular carcinoma and Of its treatment with sorafeNib) non-interventional study
    • Lencioni R., Kudo M., Ye S.L., et al. First interim analysis of the GIDEON (Global Investigation of therapeutic DEcisions in hepatocellular carcinoma and Of its treatment with sorafeNib) non-interventional study. International Journal of Clinical Practice 2012, 66(7):675-683.
    • (2012) International Journal of Clinical Practice , vol.66 , Issue.7 , pp. 675-683
    • Lencioni, R.1    Kudo, M.2    Ye, S.L.3
  • 30
    • 0032879468 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: the BCLC staging classification
    • Llovet J.M., Bru C., Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Seminars in Liver Disease 1999, 19(3):329-338.
    • (1999) Seminars in Liver Disease , vol.19 , Issue.3 , pp. 329-338
    • Llovet, J.M.1    Bru, C.2    Bruix, J.3
  • 31
    • 78149336711 scopus 로고    scopus 로고
    • Sunitinib in patients with advanced hepatocellular carcinoma after progression under sorafenib treatment
    • Worns M.A., Schuchmann M., Duber C., et al. Sunitinib in patients with advanced hepatocellular carcinoma after progression under sorafenib treatment. Oncology 2010, 79(1-2):85-92.
    • (2010) Oncology , vol.79 , Issue.1-2 , pp. 85-92
    • Worns, M.A.1    Schuchmann, M.2    Duber, C.3
  • 32
    • 84859211982 scopus 로고    scopus 로고
    • Sorafenib for recurrence of hepatocellular carcinoma after liver transplantation
    • Weinmann A., Niederle I.M., Koch S., et al. Sorafenib for recurrence of hepatocellular carcinoma after liver transplantation. Digestive and Liver Disease 2012, 44(5):432-437.
    • (2012) Digestive and Liver Disease , vol.44 , Issue.5 , pp. 432-437
    • Weinmann, A.1    Niederle, I.M.2    Koch, S.3
  • 33
    • 0021965806 scopus 로고
    • Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients
    • Okuda K., Ohtsuki T., Obata H., et al. Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer 1985, 56(4):918-928.
    • (1985) Cancer , vol.56 , Issue.4 , pp. 918-928
    • Okuda, K.1    Ohtsuki, T.2    Obata, H.3
  • 34
    • 0031782818 scopus 로고    scopus 로고
    • A., new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients: the Cancer of the Liver Italian Program (CLIP), investigators
    • A., new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients: the Cancer of the Liver Italian Program (CLIP), investigators. Hepatology 1998, 28(3):751-755.
    • (1998) Hepatology , vol.28 , Issue.3 , pp. 751-755
  • 35
    • 0038748320 scopus 로고    scopus 로고
    • Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score)
    • Kudo M., Chung H., Osaki Y. Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score). Journal of Gastroenterology 2003, 38(3):207-215.
    • (2003) Journal of Gastroenterology , vol.38 , Issue.3 , pp. 207-215
    • Kudo, M.1    Chung, H.2    Osaki, Y.3
  • 36
    • 16244369103 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: comparison of 7 staging systems in an American cohort
    • Marrero J.A., Fontana R.J., Barrat A., et al. Prognosis of hepatocellular carcinoma: comparison of 7 staging systems in an American cohort. Hepatology 2005, 41(4):707-716.
    • (2005) Hepatology , vol.41 , Issue.4 , pp. 707-716
    • Marrero, J.A.1    Fontana, R.J.2    Barrat, A.3
  • 37
    • 62749123476 scopus 로고    scopus 로고
    • Prognostic indicators in hepatocellular carcinoma: a systematic review of 72 studies
    • Tandon P., Garcia-Tsao G. Prognostic indicators in hepatocellular carcinoma: a systematic review of 72 studies. Liver International 2009, 29(4):502-510.
    • (2009) Liver International , vol.29 , Issue.4 , pp. 502-510
    • Tandon, P.1    Garcia-Tsao, G.2
  • 38
    • 33846630414 scopus 로고    scopus 로고
    • Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma
    • Uka K., Aikata H., Takaki S., et al. Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma. World Journal of Gastroenterology 2007, 13(3):414-420.
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.3 , pp. 414-420
    • Uka, K.1    Aikata, H.2    Takaki, S.3
  • 39
    • 80051717035 scopus 로고    scopus 로고
    • Management of patients with hepatocellular carcinoma and extrahepatic metastasis
    • Lee H.S. Management of patients with hepatocellular carcinoma and extrahepatic metastasis. Digestive Diseases 2011, 29(3):333-338.
    • (2011) Digestive Diseases , vol.29 , Issue.3 , pp. 333-338
    • Lee, H.S.1
  • 40
    • 80052927028 scopus 로고    scopus 로고
    • Hepatocellular carcinoma with extrahepatic metastasis: clinical features and prognostic factors
    • Uchino K., Tateishi R., Shiina S., et al. Hepatocellular carcinoma with extrahepatic metastasis: clinical features and prognostic factors. Cancer 2011, 117(19):4475-4483.
    • (2011) Cancer , vol.117 , Issue.19 , pp. 4475-4483
    • Uchino, K.1    Tateishi, R.2    Shiina, S.3
  • 41
    • 84862496492 scopus 로고    scopus 로고
    • Advanced-stage hepatocellular carcinoma: transarterial chemoembolization versus sorafenib
    • Pinter M., Hucke F., Graziadei I., et al. Advanced-stage hepatocellular carcinoma: transarterial chemoembolization versus sorafenib. Radiology 2012, 263(2):590-599.
    • (2012) Radiology , vol.263 , Issue.2 , pp. 590-599
    • Pinter, M.1    Hucke, F.2    Graziadei, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.