The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits

Cancer

Volumn 118, Issue 21, 2012, Pages 5293-5301

  Chiu, Joanne ^a   Tang, Yuen Fong ^b   Yao, Tzy Jyun ^b   Wong, Ashley ^a   Wong, Hilda ^a   Leung, Roland ^a   Chan, Pierre ^c   Cheung, Tan To ^a   Chan, Albert C ^a   Pang, Roberta ^a,b   Fan, Sheung Tat ^a,b,d   Poon, Ronnie ^a,b,d   Yau, Thomas ^a,b  

^a QUEEN MARY HOSPITAL   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c RUTTONJEE HOSPITAL   (Hong Kong)

^d THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

advanced hepatocellular carcinoma; adverse events; Child Pugh A; Child Pugh B; sorafenib

Indexed keywords

SORAFENIB;

ADULT; ADVANCED CANCER; AGED; ALOPECIA; ANEMIA; ARTICLE; CANCER SURVIVAL; CHINA; CONTROLLED STUDY; DIARRHEA; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG ERUPTION; DRUG TOLERABILITY; DRUG USE; DRUG WITHDRAWAL; FEMALE; GASTROINTESTINAL HEMORRHAGE; HAND FOOT SYNDROME; HEPATIC ENCEPHALOPATHY; HUMAN; HYPERTENSION; LEUKOPENIA; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER SURGERY; MAJOR CLINICAL STUDY; MALAISE; MALE; MUCOSA INFLAMMATION; NAUSEA; NEUTROPENIA; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RECOMMENDED DRUG DOSE; RETROSPECTIVE STUDY; SIDE EFFECT; SYSTEMIC THERAPY; THROMBOCYTOPENIA; TREATMENT OUTCOME; VOMITING;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BENZENESULFONATES; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PROTEIN KINASE INHIBITORS; PYRIDINES; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84867871965     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.27543     Document Type: Article

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