메뉴 건너뛰기




Volumn 13, Issue 2, 2013, Pages 235-241

UGT1A1 gene polymorphisms and the toxicities of FOLFIRI in Chinese Han patients with gastrointestinal cancer

Author keywords

Gastrointestinal cancer; Irinotecan; Molecular diagnosis; Predictive marker; UGT1A1 polymorphism

Indexed keywords

ATROPINE; BILIRUBIN; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; SEROTONIN 3 ANTAGONIST;

EID: 84876711885     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/1871520611313020008     Document Type: Article
Times cited : (26)

References (33)
  • 1
    • 12844277985 scopus 로고    scopus 로고
    • Estimates of cancer incidence in China for 2000 and projections for 2005
    • Yang, L.; Parkin, D.M.; Ferlay, J.; Li, L.; Chen, Y. Estimates of cancer incidence in China for 2000 and projections for 2005. Cancer Epidemiol. Biomarkers Prev., 2005, 14(1), 243-250.
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , Issue.1 , pp. 243-250
    • Yang, L.1    Parkin, D.M.2    Ferlay, J.3    Li, L.4    Chen, Y.5
  • 5
    • 52449106480 scopus 로고    scopus 로고
    • Irinotecan combined with 5-fluorouracil and leucovorin as second-line chemotherapy for metastatic or relapsed gastric cancer
    • Seo, M.D.; Lee, K.W.; Lim, J.H.; Yi, H.G.; Kim, D.Y.; Oh, D.Y.; Kim, J.H.; Im, S.A.; Kim, T.Y.; Lee, J.S.; Bang, Y.J. Irinotecan combined with 5-fluorouracil and leucovorin as second-line chemotherapy for metastatic or relapsed gastric cancer. Jpn. J. Clin. Oncol., 2008, 38(9), 589-595.
    • (2008) Jpn. J. Clin. Oncol , vol.38 , Issue.9 , pp. 589-595
    • Seo, M.D.1    Lee, K.W.2    Lim, J.H.3    Yi, H.G.4    Kim, D.Y.5    Oh, D.Y.6    Kim, J.H.7    Im, S.A.8    Kim, T.Y.9    Lee, J.S.10    Bang, Y.J.11
  • 6
    • 77954380404 scopus 로고    scopus 로고
    • Irinotecan pharmacogenomics
    • Marsh, S.; Hoskins, J.M. Irinotecan pharmacogenomics. Pharma-cogenomics, 2010, 11(7), 1003-1010.
    • (2010) Pharma-cogenomics , vol.11 , Issue.7 , pp. 1003-1010
    • Marsh, S.1    Hoskins, J.M.2
  • 7
    • 29744447165 scopus 로고    scopus 로고
    • Pharmacogenetics of irinotecan: A promoter polymorphism of UGT1A1 gene and severe adverse reactions to irinotecan
    • Ando, M.; Hasegawa, Y.; Ando, Y. Pharmacogenetics of irinotecan: a promoter polymorphism of UGT1A1 gene and severe adverse reactions to irinotecan. Invest. New Drugs, 2005, 23(6), 539-545.
    • (2005) Invest. New Drugs , vol.23 , Issue.6 , pp. 539-545
    • Ando, M.1    Hasegawa, Y.2    Ando, Y.3
  • 8
    • 33746780621 scopus 로고    scopus 로고
    • Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan
    • Nagar, S.; Blanchard, R.L. Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan. Drug Metab. Rev., 2006, 38(3), 393-409.
    • (2006) Drug Metab. Rev , vol.38 , Issue.3 , pp. 393-409
    • Nagar, S.1    Blanchard, R.L.2
  • 9
    • 59849128188 scopus 로고    scopus 로고
    • Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review
    • Palomaki, G.E.; Bradley, L.A.; Douglas, M.P.; Kolor, K.; Dotson, W.D. Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review. Genet. Med., 2009, 11(1), 21-34.
    • (2009) Genet. Med , vol.11 , Issue.1 , pp. 21-34
    • Palomaki, G.E.1    Bradley, L.A.2    Douglas, M.P.3    Kolor, K.4    Dotson, W.D.5
  • 10
    • 34748857912 scopus 로고    scopus 로고
    • Intra-ethnic differences in genetic variants of the UGT-glucuronosyltransferase 1A1 gene in Chinese populations
    • Zhang, A.; Xing, Q.; Qin, S.; Du, J.; Wang, L.; Yu, L.; Li, X.; Xu, L.; Xu, M.; Feng, G.; He, L. Intra-ethnic differences in genetic variants of the UGT-glucuronosyltransferase 1A1 gene in Chinese populations. Pharmacogenomics J., 2007, 7(5), 333-338.
    • (2007) Pharmacogenomics J , vol.7 , Issue.5 , pp. 333-338
    • Zhang, A.1    Xing, Q.2    Qin, S.3    Du, J.4    Wang, L.5    Yu, L.6    Li, X.7    Xu, L.8    Xu, M.9    Feng, G.10    He, L.11
  • 13
    • 67149106945 scopus 로고    scopus 로고
    • Common Terminology Criteria for Adverse Events, Version 3.0
    • Common Terminology Criteria for Adverse Events, Version 3.0. Cancer Therapy Evaluation Program, 2006.
    • (2006) Cancer Therapy Evaluation Program
  • 14
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse, P.; Arbuck, S.G.; Eisenhauer, E.A.; Wanders, J.; Kaplan, R.S.; Rubinstein, L.; Verweij, J.; Van Glabbeke, M.; van Oosterom, A.T.; Christian, M.C.; Gwyther, S.G. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J. Natl. Cancer Inst., 2000, 92(3), 205-216.
    • (2000) J. Natl. Cancer Inst , vol.92 , Issue.3 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6    Verweij, J.7    van Glabbeke, M.8    van Oosterom, A.T.9    Christian, M.C.10    Gwyther, S.G.11
  • 15
    • 33744804311 scopus 로고    scopus 로고
    • Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin
    • Han, J.Y.; Lim, H.S.; Shin, E.S.; Yoo, Y.K.; Park, Y.H.; Lee, J.E.; Jang, I.J.; Lee, D.H.; Lee, J.S. Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin. J. Clin. Oncol., 2006, 24(15), 2237-2244.
    • (2006) J. Clin. Oncol , vol.24 , Issue.15 , pp. 2237-2244
    • Han, J.Y.1    Lim, H.S.2    Shin, E.S.3    Yoo, Y.K.4    Park, Y.H.5    Lee, J.E.6    Jang, I.J.7    Lee, D.H.8    Lee, J.S.9
  • 16
    • 66349133649 scopus 로고    scopus 로고
    • Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan
    • Cecchin, E.; Innocenti, F.; D'Andrea, M.; Corona, G.; De Mattia, E.; Biason, P.; Buonadonna, A.; Toffoli, G. Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan. J. Clin. Oncol., 2009, 27(15), 2457-2465.
    • (2009) J. Clin. Oncol , vol.27 , Issue.15 , pp. 2457-2465
    • Cecchin, E.1    Innocenti, F.2    D'andrea, M.3    Corona, G.4    de Mattia, E.5    Biason, P.6    Buonadonna, A.7    Toffoli, G.8
  • 17
    • 42449139713 scopus 로고    scopus 로고
    • UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma
    • Liu, C.Y.; Chen, P.M.; Chiou, T.J.; Liu, J.H.; Lin, J.K.; Lin, T.C.; Chen, W.S.; Jiang, J.K.; Wang, H.S.; Wang, W.S. UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma. Cancer, 2008, 112(9), 1932-1940.
    • (2008) Cancer , vol.112 , Issue.9 , pp. 1932-1940
    • Liu, C.Y.1    Chen, P.M.2    Chiou, T.J.3    Liu, J.H.4    Lin, J.K.5    Lin, T.C.6    Chen, W.S.7    Jiang, J.K.8    Wang, H.S.9    Wang, W.S.10
  • 21
    • 34547788826 scopus 로고    scopus 로고
    • Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients
    • Jada, S.R.; Lim, R.; Wong, C.I.; Shu, X.; Lee, S.C.; Zhou, Q.; Goh, B.C.; Chowbay, B. Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients. Cancer Sci., 2007, 98(9), 1461-1467.
    • (2007) Cancer Sci , vol.98 , Issue.9 , pp. 1461-1467
    • Jada, S.R.1    Lim, R.2    Wong, C.I.3    Shu, X.4    Lee, S.C.5    Zhou, Q.6    Goh, B.C.7    Chowbay, B.8
  • 23
    • 77955166242 scopus 로고    scopus 로고
    • Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: Low doses also increase risk
    • Hu, Z.Y.; Yu, Q.; Pei, Q.; Guo, C. Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: low doses also increase risk. Clin. Cancer Res., 2010, 16(15), 3832-3842.
    • (2010) Clin. Cancer Res , vol.16 , Issue.15 , pp. 3832-3842
    • Hu, Z.Y.1    Yu, Q.2    Pei, Q.3    Guo, C.4
  • 24
    • 84859403361 scopus 로고    scopus 로고
    • Phase II study of cetuximab in combination with modified FOLFIRI in patients with advanced gastric cancer who failed first-line chemotherapy (EFFI study)
    • abstr 4107
    • Li, J.; Liu, X.; Wang, B.Y.; Guo, W.J.; Yin, J.L.; Zhu, X.D.; Zhang, J.; Liu, T. Phase II study of cetuximab in combination with modified FOLFIRI in patients with advanced gastric cancer who failed first-line chemotherapy (EFFI study). J. Clin. Oncol., 2010, 28(15s), suppl; abstr 4107.
    • (2010) J. Clin. Oncol , vol.28 , Issue.15
    • Li, J.1    Liu, X.2    Wang, B.Y.3    Guo, W.J.4    Yin, J.L.5    Zhu, X.D.6    Zhang, J.7    Liu, T.8
  • 27
    • 0842301047 scopus 로고    scopus 로고
    • Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: Significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects with the UGT1A1*28 variant
    • Fang, J.L.; Lazarus, P. Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects with the UGT1A1*28 variant. Cancer Epidemiol. Biomarkers Prev., 2004, 13(1), 102-109.
    • (2004) Cancer Epidemiol. Biomarkers Prev , vol.13 , Issue.1 , pp. 102-109
    • Fang, J.L.1    Lazarus, P.2
  • 28
    • 2342584118 scopus 로고    scopus 로고
    • Relationship of baseline serum bilirubin to efficacy and toxicity of single-agent irinotecan in patients with metastatic colorectal cancer
    • Meyerhardt, J.A.; Kwok, A.; Ratain, M.J.; McGovren, J.P.; Fuchs, C.S. Relationship of baseline serum bilirubin to efficacy and toxicity of single-agent irinotecan in patients with metastatic colorectal cancer. J. Clin. Oncol., 2004, 22(8), 1439-1446.
    • (2004) J. Clin. Oncol , vol.22 , Issue.8 , pp. 1439-1446
    • Meyerhardt, J.A.1    Kwok, A.2    Ratain, M.J.3    McGovren, J.P.4    Fuchs, C.S.5
  • 29
    • 77953459452 scopus 로고    scopus 로고
    • Utility of Pretreatment Bilirubin Level and UGT1A1 Polymorphisms in Multivariate Predictive Models of Neutropenia Associated with Irinotecan Treatment in Previously Untreated Patients with Colorectal Cancer
    • Parodi, L.; Pickering, E.; Cisar, L.A.; Lee, D.; Soufi-Mahjoubi, R. Utility of Pretreatment Bilirubin Level and UGT1A1 Polymorphisms in Multivariate Predictive Models of Neutropenia Associated with Irinotecan Treatment in Previously Untreated Patients with Colorectal Cancer. Arch Drug Inf., 2008, 1(3), 97-106.
    • (2008) Arch Drug Inf , vol.1 , Issue.3 , pp. 97-106
    • Parodi, L.1    Pickering, E.2    Cisar, L.A.3    Lee, D.4    Soufi-Mahjoubi, R.5
  • 30
    • 53649102831 scopus 로고    scopus 로고
    • Clinical and pharmacogenetic factors associated with irinotecan toxicity
    • Kweekel, D.; Guchelaar, H.J.; Gelderblom, H. Clinical and pharmacogenetic factors associated with irinotecan toxicity. Cancer Treat. Rev., 2008, 34(7), 656-669.
    • (2008) Cancer Treat. Rev , vol.34 , Issue.7 , pp. 656-669
    • Kweekel, D.1    Guchelaar, H.J.2    Gelderblom, H.3
  • 31
    • 36048960109 scopus 로고    scopus 로고
    • Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C Study
    • Fuchs, C.S.; Marshall, J.; Mitchell, E.; Wierzbicki, R.; Ganju, V.; Jeffery, M.; Schulz, J.; Richards, D.; Soufi-Mahjoubi, R.; Wang, B.; Barrueco, J. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. J. Clin. Oncol., 2007, 25(30), 4779-4786.
    • (2007) J. Clin. Oncol , vol.25 , Issue.30 , pp. 4779-4786
    • Fuchs, C.S.1    Marshall, J.2    Mitchell, E.3    Wierzbicki, R.4    Ganju, V.5    Jeffery, M.6    Schulz, J.7    Richards, D.8    Soufi-Mahjoubi, R.9    Wang, B.10    Barrueco, J.11
  • 32
    • 77953289476 scopus 로고    scopus 로고
    • Dose-dependent association between UGT1A1*28 polymorphism and irinotecan-induced diarrhoea: A meta-analysis
    • Hu, Z.Y.; Yu, Q.; Zhao, Y.S. Dose-dependent association between UGT1A1*28 polymorphism and irinotecan-induced diarrhoea: a meta-analysis. Eur. J. Cancer, 2010, 46(10), 1856-1865.
    • (2010) Eur. J. Cancer , vol.46 , Issue.10 , pp. 1856-1865
    • Hu, Z.Y.1    Yu, Q.2    Zhao, Y.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.