Protective effect of Sida cordata leaf extract against CCl4 induced acute liver toxicity in rats

Asian Pacific Journal of Tropical Medicine

Volumn 6, Issue 4, 2013, Pages 280-284

  Mistry, Sunil ^a   Dutt, K R ^b   Jena, J ^c  

^a Gayatri College of Pharmacy   (India)

^b CMR college of Pharmacy   (India)

^c SAMBALPUR UNIVERSITY   (India)

Author keywords

CCl4; Hepatoprotective; Histopathology; Sida cordata

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; CATALASE; GLUTATHIONE; PLANT EXTRACT; SIDA CORDATA EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER; LIVER PROTECTION; LIVER TOXICITY; MALE; MALVACEAE; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; RAT; SIDA CORDATA; SINGLE DRUG DOSE;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CATALASE; DRUG-INDUCED LIVER INJURY; FEMALE; GLUTATHIONE; LIPID PEROXIDATION; MALE; MALVACEAE; MICE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 84876708433     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(13)60057-7     Document Type: Article

References (28)

1. Shahani S Evaluation of hepatoprotective efficacy of APCL-A polyherbal formulation in vivo in rats. Indian Drugs 1999, 36:628-631.
2. 4-induced liver injury and survival in rats. J Ethnopharmacol 1997, 56:159-164.
3. Valiathan MS The legacy of Charaka 2003, 123-132. Indian academy of sciences, Orient Longman, Delhi.
4. Warrier PK, Nambiar VPK, Ramankutty C Indian medicinal plants: Compendium of 500 species 1994, vol. 5:129-131. Orient Longman, Hyderabad.
5. Babu K, Deepa MA, Gokul SS, Rai S Anatomical studies on bala- An ayurvedic drug and its varieties. Phcog J 2009, 1(1):37-43.
6. Sivarajan VV Indian Balachandran: Ayurvedic drugs and their sources 1994, 71-79. Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi.
7. Khandelwal KR Practical pharmacognosy techniques and experiment 2008, 149-156. Niraliprakashan, New Delhi. 9th ed.
8. Organisation for Economic Co-operation and Development OECD guideline for the testing of chemicals revised draft guideline 423: Acute oral toxicity 2000, OECD, Paris.
9. 4 induced hepatic damage in rats. Afri J Biochem Res 2008, 2:61-65.
10. GPT/ALAT UV Kinetic test [package insert] 2006, Agappe Diagnostics Pvt. Ltd, Ernakulam (KL).
11. GOT/ASAT UV Kinetic test [package insert] 2006, Agappe Diagnostics Pvt. Ltd, Ernakulam (KL).
12. Alkaline phosphatase P-NPP method [package insert] 2006, Agappe Diagnostics Pvt. Ltd, Ernakulam (KL).
13. Bilirubin total and direct [package insert] 2006, Agappe Diagnostics Pvt. Ltd, Ernakulam (KL).
14. Ohkawa H, Ohishi N, Yagi K Assayof lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochem 1979, 95:351-358.
15. Naik RS, Majumdar AM, Ghaskabdi S Protection of liver cells from ethanol toxicity by curcumin in liver slice culture in vitro. J Ethnopharmacol 2004, 95:31-37.
16. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ Protein measurement with the Folin phenol reagent. J BiolChem 1951, 193:265-275.
17. Pari L, Latha M Protective role of Scoparia dulcis plant extract on brain antioxidant status and lipid peroxidation in STZ diabetic male wister rats. BMC Compliment Altern Med 2004, 4:6882-6884.
18. Ellman GL Tissue sulfhydryl groups. Arch BiochemBiophys 1959, 82:70-77.
19. Sinha AK Colorimetric assay of catalase. Analytical Biochem 1972, 47:389-394.
20. Gennaro AR Remigton: The science and practice of pharmacy 1995, Vol 1:111. Mac Publishing Co, Easton PA. 19th ed.
21. Lima TB, Suja A, Jisa OS, Sathyanarayanan S, Remya KS Hepatoprotective activity of LIV-first against carbon tetra chloride-induced hepatotoxicity in albino rats. Int J Green pharmacy 2010, 4:71-74.
22. Suresh kumar SV, Mishra SH Hepatoprotective activity of extracts from Pergularia daemia Forsk. against carbon tetrachloride induced toxicity in rats. Pharmacogn Mag 2007, 3(11):187-191.
23. Kuriakose GC, Kurup MG Hepatoprotective effect of Spirulina lonar on paracetamol induced liver damage in rats. Asian J Exp Biol Sci 2010, 1(3):614-623.
24. Kumawat R, Sharma S, Vasudeva N, Kumar S In vivo anti-inflamatory potential of various extracts of Sida tiagii Bhandari. Asian Pac J Trop Biomed 2012, 2(Suppl 2):S947-S952.
25. Hurkadale PJ, Shelar PA, Palled SG, Mandavkar YD, Khedkar AS Hepatoprotective activity of Amorphophallus paeoniifolius tubers against paracetamol-induced liver damage in rats. Asian Pac J Trop Biomed 2012, 2(Suppl 1):S238-S242.
26. 4 -induced liver toxicity in rats. Asian Pac J Trop Dis 2012, 2(Suppl 1):S208-S211.
27. Amresh G, Kant R, Zeashan H, Gupta RJ, RaoCh V, Singh PN Gastroprotective effects of ethanolic extracts from Cissampelo spareira in experimental animals. J Nat Med 2007, 6:323-328.
28. Garba SH, Prasad J, Sandabe UK Hepatoprotective effect of the aqueous root bark extract of Ficus syncomorus Linn on carbon tetrachloride induced hepatotoxicity in rats. J Biol Sci 2007, 7(2):276-281.