Preparation and evaluation of copolymeric micelles with high paclitaxel contents and sustained drug release

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 429, Issue , 2013, Pages 12-18

  Li, Yanggong ^a   Xu, Xiaofen ^a   Shen, Yuanyuan ^a   Qian, Changyun ^a   Lu, Fei ^a   Guo, Shengrong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

High drug loading; Micelle; Paclitaxel; Solubility; Sustained release

Indexed keywords

BLOCK COPOLYMERS; CRITICAL MICELLE CONCENTRATION; DISPERSIONS; DRUG PRODUCTS; ENCAPSULATION; ETHYLENE GLYCOL; GEL PERMEATION CHROMATOGRAPHY; LOADING; MOTION PICTURE EXPERTS GROUP STANDARDS; POWDERS; SOLUBILITY;

AMPHIPHILIC BLOCK COPOLYMERS; CRITICAL MICELLE CONCENTRATION (CMC); ENCAPSULATION EFFICIENCY; GEL PERMEATION CHROMATOGRAPHY (GPC); HIGH DRUG LOADINGS; HYDROPHILIC AND HYDROPHOBIC; PACLITAXEL; SUSTAINED RELEASE;

MICELLES;

COPOLYMER; METHOXYPOLY(ETHYLENE GLYCOL) B POLY(EPSILON CAPROLACTONE CO LACTIDE); PACLITAXEL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CRITICAL MICELLE CONCENTRATION; CRYSTALLIZATION; CYTOTOXICITY; DISPERSION; DRUG SCREENING; DRUG SYNTHESIS; GEL PERMEATION CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; LYOPHILISATE; MICELLE; MICROENCAPSULATION; MOLECULAR WEIGHT; MORPHOLOGY; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLUBILITY; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; ULTRASOUND;

EID: 84876701245     PISSN: 09277757     EISSN: 18734359     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2013.03.043     Document Type: Article

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