메뉴 건너뛰기




Volumn 125, Issue 4, 2013, Pages 491-509

Neural plasticity in the gastrointestinal tract: Chronic inflammation, neurotrophic signals, and hypersensitivity

Author keywords

Enteric nervous system; Gastrointestinal tract; Hypersensitivity; Neural plasticity; Neuro inflammation; Pain

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCITONIN GENE RELATED PEPTIDE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEURONAL NITRIC OXIDE SYNTHASE; NEUROTROPHIN 3; NEUROTROPHIN 4; PROTEINASE ACTIVATED RECEPTOR 2; PURINERGIC P2X RECEPTOR; SUBSTANCE P; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; VANILLOID RECEPTOR 1; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 84876673184     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-013-1099-4     Document Type: Review
Times cited : (66)

References (119)
  • 1
    • 77953718071 scopus 로고    scopus 로고
    • Expression of the TRPV1 receptor differs in quiescent inflammatory bowel disease with or without abdominal pain
    • 20551462 10.1136/gut.2009.194449
    • Akbar A, Yiangou Y, Facer P, Brydon WG, Walters JR, Anand P, Ghosh S (2010) Expression of the TRPV1 receptor differs in quiescent inflammatory bowel disease with or without abdominal pain. Gut 59(6):767-774
    • (2010) Gut , vol.59 , Issue.6 , pp. 767-774
    • Akbar, A.1    Yiangou, Y.2    Facer, P.3    Brydon, W.G.4    Walters, J.R.5    Anand, P.6    Ghosh, S.7
  • 2
    • 0032125501 scopus 로고    scopus 로고
    • Mast cell, myofibroblast and nerve terminal complexes in carbon tetrachloride-induced cirrhotic rat livers
    • 9696499 1:STN:280:DyaK1czlvFKrug%3D%3D 10.1016/S0168-8278(98)80185-2
    • Akiyoshi H, Terada T (1998) Mast cell, myofibroblast and nerve terminal complexes in carbon tetrachloride-induced cirrhotic rat livers. J Hepatol 29(1):112-119
    • (1998) J Hepatol , vol.29 , Issue.1 , pp. 112-119
    • Akiyoshi, H.1    Terada, T.2
  • 3
    • 80054822430 scopus 로고    scopus 로고
    • Neurogenesis in colorectal cancer is a marker of aggressive tumor behavior and poor outcomes
    • 21480205 1:CAS:528:DC%2BC3MXhtlaqu7%2FF 10.1002/cncr.26117
    • Albo D, Akay CL, Marshall CL, Wilks JA, Verstovsek G, Liu H, Agarwal N, Berger DH, Ayala GE (2011) Neurogenesis in colorectal cancer is a marker of aggressive tumor behavior and poor outcomes. Cancer 117(21):4834-4845
    • (2011) Cancer , vol.117 , Issue.21 , pp. 4834-4845
    • Albo, D.1    Akay, C.L.2    Marshall, C.L.3    Wilks, J.A.4    Verstovsek, G.5    Liu, H.6    Agarwal, N.7    Berger, D.H.8    Ayala, G.E.9
  • 4
    • 34447540326 scopus 로고    scopus 로고
    • Effect of reflux-induced inflammation on transient receptor potential vanilloid one (TRPV1) expression in primary sensory neurons innervating the oesophagus of rats
    • 17640184 1:CAS:528:DC%2BD2sXhtFyjsr7J 10.1111/j.1365-2982.2007.00947.x
    • Banerjee B, Medda BK, Lazarova Z, Bansal N, Shaker R, Sengupta JN (2007) Effect of reflux-induced inflammation on transient receptor potential vanilloid one (TRPV1) expression in primary sensory neurons innervating the oesophagus of rats. Neurogastroenterol Motil 19(8):681-691
    • (2007) Neurogastroenterol Motil , vol.19 , Issue.8 , pp. 681-691
    • Banerjee, B.1    Medda, B.K.2    Lazarova, Z.3    Bansal, N.4    Shaker, R.5    Sengupta, J.N.6
  • 5
    • 58249104041 scopus 로고    scopus 로고
    • Alterations in N-methyl-d-aspartate receptor subunits in primary sensory neurons following acid-induced esophagitis in cats
    • 18974310 1:CAS:528:DC%2BD1MXpsFCmtQ%3D%3D 10.1152/ajpgi.90419.2008
    • Banerjee B, Medda BK, Zheng Y, Miller H, Miranda A, Sengupta JN, Shaker R (2009) Alterations in N-methyl-d-aspartate receptor subunits in primary sensory neurons following acid-induced esophagitis in cats. Am J Physiol Gastrointest Liver Physiol 296(1):G66-G77
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , Issue.1
    • Banerjee, B.1    Medda, B.K.2    Zheng, Y.3    Miller, H.4    Miranda, A.5    Sengupta, J.N.6    Shaker, R.7
  • 6
    • 80053162486 scopus 로고    scopus 로고
    • Perineural invasion and associated pain in pancreatic cancer
    • 21941281 1:CAS:528:DC%2BC3MXht1ajurjM 10.1038/nrc3131
    • Bapat AA, Hostetter G, Von Hoff DD, Han H (2011) Perineural invasion and associated pain in pancreatic cancer. Nat Rev Cancer 11(10):695-707
    • (2011) Nat Rev Cancer , vol.11 , Issue.10 , pp. 695-707
    • Bapat, A.A.1    Hostetter, G.2    Von Hoff, D.D.3    Han, H.4
  • 9
    • 0036789658 scopus 로고    scopus 로고
    • Immune-mediated neural dysfunction in a murine model of chronic Helicobacter pylori infection
    • 12360482 1:CAS:528:DC%2BD38Xotl2ns70%3D 10.1053/gast.2002.36024
    • Bercik P, De Giorgio R, Blennerhassett P, Verdu EF, Barbara G, Collins SM (2002) Immune-mediated neural dysfunction in a murine model of chronic Helicobacter pylori infection. Gastroenterology 123(4):1205-1215
    • (2002) Gastroenterology , vol.123 , Issue.4 , pp. 1205-1215
    • Bercik, P.1    De Giorgio, R.2    Blennerhassett, P.3    Verdu, E.F.4    Barbara, G.5    Collins, S.M.6
  • 10
    • 3042636956 scopus 로고    scopus 로고
    • Symptom hypersensitivity to acid infusion is associated with hypersensitivity of esophageal contractility
    • 14977636 1:CAS:528:DC%2BD2cXlvFOgsrw%3D 10.1152/ajpgi.00420.2003
    • Bhalla V, Liu J, Puckett JL, Mittal RK (2004) Symptom hypersensitivity to acid infusion is associated with hypersensitivity of esophageal contractility. Am J Physiol Gastrointest Liver Physiol 287(1):G65-G71
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , Issue.1
    • Bhalla, V.1    Liu, J.2    Puckett, J.L.3    Mittal, R.K.4
  • 11
    • 0036182217 scopus 로고    scopus 로고
    • Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats
    • 11875008 1:CAS:528:DC%2BD38Xit1ejt7Y%3D 10.1053/gast.2002.31901
    • Bielefeldt K, Ozaki N, Gebhart GF (2002) Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats. Gastroenterology 122(3):752-761
    • (2002) Gastroenterology , vol.122 , Issue.3 , pp. 752-761
    • Bielefeldt, K.1    Ozaki, N.2    Gebhart, G.F.3
  • 15
    • 70350492934 scopus 로고    scopus 로고
    • Pancreatic neuropathy results in "neural remodeling" and altered pancreatic innervation in chronic pancreatitis and pancreatic cancer
    • 19568227 10.1038/ajg.2009.380
    • Ceyhan GO, Demir IE, Rauch U, Bergmann F, Muller MW, Buchler MW, Friess H, Schafer KH (2009) Pancreatic neuropathy results in "neural remodeling" and altered pancreatic innervation in chronic pancreatitis and pancreatic cancer. Am J Gastroenterol 104(10):2555-2565
    • (2009) Am J Gastroenterol , vol.104 , Issue.10 , pp. 2555-2565
    • Ceyhan, G.O.1    Demir, I.E.2    Rauch, U.3    Bergmann, F.4    Muller, M.W.5    Buchler, M.W.6    Friess, H.7    Schafer, K.H.8
  • 17
    • 34247491920 scopus 로고    scopus 로고
    • Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation
    • 17307183 1:CAS:528:DC%2BD2sXkslWru7c%3D 10.1016/j.ijpara.2006.12.018
    • Chen Z, Suntres Z, Palmer J, Guzman J, Javed A, Xue J, Yu JG, Cooke H, Awad H, Hassanain HH, Cardounel AJ, Christofi FL (2007) Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation. Int J Parasitol 37(7):743-761
    • (2007) Int J Parasitol , vol.37 , Issue.7 , pp. 743-761
    • Chen, Z.1    Suntres, Z.2    Palmer, J.3    Guzman, J.4    Javed, A.5    Xue, J.6    Yu, J.G.7    Cooke, H.8    Awad, H.9    Hassanain, H.H.10    Cardounel, A.J.11    Christofi, F.L.12
  • 18
    • 84855341203 scopus 로고    scopus 로고
    • Randomised clinical trial: Pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - A placebo-controlled study
    • 22211824 1:CAS:528:DC%2BC38XjtFKgtbw%3D 10.1111/j.1365-2036.2011.04955.x
    • Chua YC, Ng KS, Sharma A, Jafari J, Surguy S, Yazaki E, Knowles CH, Aziz Q (2012) Randomised clinical trial: pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - a placebo-controlled study. Aliment Pharmacol Ther 35(3):319-326
    • (2012) Aliment Pharmacol Ther , vol.35 , Issue.3 , pp. 319-326
    • Chua, Y.C.1    Ng, K.S.2    Sharma, A.3    Jafari, J.4    Surguy, S.5    Yazaki, E.6    Knowles, C.H.7    Aziz, Q.8
  • 19
    • 0036862460 scopus 로고    scopus 로고
    • Mast cell density, neuronal hypertrophy and nerve growth factor expression in patients with acute appendicitis
    • Coskun N, Sindel M, Elpek GO (2002) Mast cell density, neuronal hypertrophy and nerve growth factor expression in patients with acute appendicitis. Folia Morphol (Warsz) 61(4):237-243
    • (2002) Folia Morphol (Warsz) , vol.61 , Issue.4 , pp. 237-243
    • Coskun, N.1    Sindel, M.2    Elpek, G.O.3
  • 20
    • 19344363323 scopus 로고    scopus 로고
    • Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons
    • 15673552 1:CAS:528:DC%2BD2MXlsV2qurc%3D 10.1152/jn.01127.2004
    • Dang K, Bielfeldt K, Lamb K, Gebhart GF (2005) Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons. J Neurophysiol 93(6):3112-3119
    • (2005) J Neurophysiol , vol.93 , Issue.6 , pp. 3112-3119
    • Dang, K.1    Bielfeldt, K.2    Lamb, K.3    Gebhart, G.F.4
  • 22
    • 33846959506 scopus 로고    scopus 로고
    • Acute distal colitis impairs gastric emptying in rats via an extrinsic neuronal reflex pathway involving the pelvic nerve
    • 16973715 10.1136/gut.2006.104745 1:CAS:528:DC%2BD2sXivF2gt7o%3D
    • De Schepper HU, De Man JG, Van Nassauw L, Timmermans JP, Herman AG, Pelckmans PA, De Winter BY (2007) Acute distal colitis impairs gastric emptying in rats via an extrinsic neuronal reflex pathway involving the pelvic nerve. Gut 56(2):195-202
    • (2007) Gut , vol.56 , Issue.2 , pp. 195-202
    • De Schepper, H.U.1    De Man, J.G.2    Van Nassauw, L.3    Timmermans, J.P.4    Herman, A.G.5    Pelckmans, P.A.6    De Winter, B.Y.7
  • 23
    • 79952258278 scopus 로고    scopus 로고
    • Neural invasion in pancreatic cancer: The past, present and future
    • 1:CAS:528:DC%2BC3cXptVGrt7g%3D 10.3390/cancers2031513
    • Demir IE, Ceyhan GO, Liebl F, D'Haese JG, Maak M, Friess H (2010) Neural invasion in pancreatic cancer: the past, present and future. Cancers 2(3):1513-1527
    • (2010) Cancers , vol.2 , Issue.3 , pp. 1513-1527
    • Demir, I.E.1    Ceyhan, G.O.2    Liebl, F.3    D'Haese, J.G.4    Maak, M.5    Friess, H.6
  • 28
    • 0019119828 scopus 로고
    • Crohn's disease: Transmission electron microscopic studies. III. Target tissues. Proliferation of and injury to smooth muscle and the autonomic nervous system
    • 6161074 1:STN:280:DyaL3M%2Fpt1Chug%3D%3D 10.1016/S0046-8177(80)80073-6
    • Dvorak AM, Osage JE, Monahan RA, Dickersin GR (1980) Crohn's disease: transmission electron microscopic studies. III. Target tissues. Proliferation of and injury to smooth muscle and the autonomic nervous system. Hum Pathol 11(6):620-634
    • (1980) Hum Pathol , vol.11 , Issue.6 , pp. 620-634
    • Dvorak, A.M.1    Osage, J.E.2    Monahan, R.A.3    Dickersin, G.R.4
  • 30
    • 77950862981 scopus 로고    scopus 로고
    • Astrocytic activation in thoracic spinal cord contributes to persistent pain in rat model of chronic pancreatitis
    • 20149842 1:CAS:528:DC%2BC3cXksVehtrc%3D 10.1016/j.neuroscience.2010.02. 005
    • Feng QX, Wang W, Feng XY, Mei XP, Zhu C, Liu ZC, Li YQ, Dou KF, Zhao QC (2010) Astrocytic activation in thoracic spinal cord contributes to persistent pain in rat model of chronic pancreatitis. Neuroscience 167(2):501-509
    • (2010) Neuroscience , vol.167 , Issue.2 , pp. 501-509
    • Feng, Q.X.1    Wang, W.2    Feng, X.Y.3    Mei, X.P.4    Zhu, C.5    Liu, Z.C.6    Li, Y.Q.7    Dou, K.F.8    Zhao, Q.C.9
  • 31
    • 80052335918 scopus 로고    scopus 로고
    • Substance P immunoreactive nerve fibres are related to gastric cancer differentiation status and could promote proliferation and migration of gastric cancer cells
    • 21091434 1:CAS:528:DC%2BC3MXlvVCgtbk%3D 10.1042/CBI20100229
    • Feng F, Yang J, Tong L, Yuan S, Tian Y, Hong L, Wang W, Zhang H (2011) Substance P immunoreactive nerve fibres are related to gastric cancer differentiation status and could promote proliferation and migration of gastric cancer cells. Cell Biol Int 35(6):623-629
    • (2011) Cell Biol Int , vol.35 , Issue.6 , pp. 623-629
    • Feng, F.1    Yang, J.2    Tong, L.3    Yuan, S.4    Tian, Y.5    Hong, L.6    Wang, W.7    Zhang, H.8
  • 32
    • 35348887849 scopus 로고    scopus 로고
    • Pain in chronic pancreatitis: A salutogenic mechanism or a maladaptive brain response?
    • 17898531 10.1159/000108958
    • Fregni F, Pascual-Leone A, Freedman SD (2007) Pain in chronic pancreatitis: a salutogenic mechanism or a maladaptive brain response? Pancreatology 7(5-6):411-422
    • (2007) Pancreatology , vol.7 , Issue.5-6 , pp. 411-422
    • Fregni, F.1    Pascual-Leone, A.2    Freedman, S.D.3
  • 34
    • 0024459450 scopus 로고
    • Migration of the myoelectric complex after interruption of the myenteric plexus: Intestinal transection and regeneration of enteric nerves in the guinea pig
    • 2571545 1:STN:280:DyaK3c%2Fgs1GmtQ%3D%3D
    • Galligan JJ, Furness JB, Costa M (1989) Migration of the myoelectric complex after interruption of the myenteric plexus: intestinal transection and regeneration of enteric nerves in the guinea pig. Gastroenterology 97(5):1135-1146
    • (1989) Gastroenterology , vol.97 , Issue.5 , pp. 1135-1146
    • Galligan, J.J.1    Furness, J.B.2    Costa, M.3
  • 35
    • 79954542151 scopus 로고    scopus 로고
    • ERK1/2 signaling pathway in mast cell activation-induced sensitization of esophageal nodose C-fiber neurons
    • 21073620 1:STN:280:DC%2BC3Mvjt1WhtQ%3D%3D 10.1111/j.1442-2050.2010.01127. x
    • Gao G, Ouyang A, Kaufman MP, Yu S (2011) ERK1/2 signaling pathway in mast cell activation-induced sensitization of esophageal nodose C-fiber neurons. Dis Esophagus 24(3):194-203
    • (2011) Dis Esophagus , vol.24 , Issue.3 , pp. 194-203
    • Gao, G.1    Ouyang, A.2    Kaufman, M.P.3    Yu, S.4
  • 36
    • 41849088450 scopus 로고    scopus 로고
    • Reduction of interstitial cells of Cajal (ICC) associated with neuronal nitric oxide synthase (n-NOS) in patients with achalasia
    • 18070236 10.1111/j.1572-0241.2007.01667.x
    • Gockel I, Bohl JR, Eckardt VF, Junginger T (2008) Reduction of interstitial cells of Cajal (ICC) associated with neuronal nitric oxide synthase (n-NOS) in patients with achalasia. Am J Gastroenterol 103(4):856-864
    • (2008) Am J Gastroenterol , vol.103 , Issue.4 , pp. 856-864
    • Gockel, I.1    Bohl, J.R.2    Eckardt, V.F.3    Junginger, T.4
  • 37
    • 77954371056 scopus 로고    scopus 로고
    • Morphological changes in the enteric nervous system caused by carcinoma of the human large intestine
    • 20529833 10.2478/v10042-010-0029-8
    • Godlewski J (2010) Morphological changes in the enteric nervous system caused by carcinoma of the human large intestine. Folia Histochem Cytobiol 48(1):157-162
    • (2010) Folia Histochem Cytobiol , vol.48 , Issue.1 , pp. 157-162
    • Godlewski, J.1
  • 38
    • 34548833925 scopus 로고    scopus 로고
    • Effects of melatonin on gallbladder neuromuscular function in acute cholecystitis
    • 17615302 1:CAS:528:DC%2BD2sXhtFahsLbE 10.1124/jpet.107.123240
    • Gomez-Pinilla PJ, Camello PJ, Pozo MJ (2007) Effects of melatonin on gallbladder neuromuscular function in acute cholecystitis. J Pharmacol Exp Ther 323(1):138-146
    • (2007) J Pharmacol Exp Ther , vol.323 , Issue.1 , pp. 138-146
    • Gomez-Pinilla, P.J.1    Camello, P.J.2    Pozo, M.J.3
  • 39
    • 0029068598 scopus 로고
    • Hyperplastic innervation of vasoactive intestinal peptide in human gallbladder with cholelithiasis
    • 7579816 1:CAS:528:DyaK2MXoslGqtr8%3D
    • Gonda T, Akiyoshi H, Ichihara K (1995) Hyperplastic innervation of vasoactive intestinal peptide in human gallbladder with cholelithiasis. Histol Histopathol 10(3):669-672
    • (1995) Histol Histopathol , vol.10 , Issue.3 , pp. 669-672
    • Gonda, T.1    Akiyoshi, H.2    Ichihara, K.3
  • 41
    • 34250186399 scopus 로고    scopus 로고
    • Association between gallstone-evoked pain, inflammation and proliferation of nerves in the gallbladder: A possible explanation for clinical differences
    • 17558913 10.1080/00365520701207074
    • Hennig R, Zanli J, Osman T, Esposito I, Berhane T, Vetrhus M, Sondenaa K, Buchler MW, Friess H (2007) Association between gallstone-evoked pain, inflammation and proliferation of nerves in the gallbladder: a possible explanation for clinical differences. Scand J Gastroenterol 42(7):878-884
    • (2007) Scand J Gastroenterol , vol.42 , Issue.7 , pp. 878-884
    • Hennig, R.1    Zanli, J.2    Osman, T.3    Esposito, I.4    Berhane, T.5    Vetrhus, M.6    Sondenaa, K.7    Buchler, M.W.8    Friess, H.9
  • 42
    • 2942690105 scopus 로고    scopus 로고
    • Development of esophageal hypersensitivity following experimental duodenal acidification
    • 15128342 10.1111/j.1572-0241.2004.04167.x
    • Hobson AR, Khan RW, Sarkar S, Furlong PL, Aziz Q (2004) Development of esophageal hypersensitivity following experimental duodenal acidification. Am J Gastroenterol 99(5):813-820
    • (2004) Am J Gastroenterol , vol.99 , Issue.5 , pp. 813-820
    • Hobson, A.R.1    Khan, R.W.2    Sarkar, S.3    Furlong, P.L.4    Aziz, Q.5
  • 43
    • 0019960373 scopus 로고
    • Neurogenic appendicopathy - An immunocytochemical study
    • 6188281 1:STN:280:DyaL3s7ntlymsA%3D%3D
    • Hofler H, Heitz PU (1982) Neurogenic appendicopathy - an immunocytochemical study. Wien Klin Wochenschr 94(21):588-591
    • (1982) Wien Klin Wochenschr , vol.94 , Issue.21 , pp. 588-591
    • Hofler, H.1    Heitz, P.U.2
  • 45
    • 72449210563 scopus 로고    scopus 로고
    • Post-inflammatory modification of colonic afferent mechanosensitivity
    • 19566823 1:CAS:528:DC%2BD1MXhsVSkur%2FM 10.1111/j.1440-1681.2009.05248.x
    • Hughes PA, Brierley SM, Blackshaw LA (2009) Post-inflammatory modification of colonic afferent mechanosensitivity. Clin Exp Pharmacol Physiol 36(10):1034-1040
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , Issue.10 , pp. 1034-1040
    • Hughes, P.A.1    Brierley, S.M.2    Blackshaw, L.A.3
  • 46
  • 47
    • 0027745299 scopus 로고
    • Toxic hepatic injury is associated with proliferation of portal nerve fibers
    • 8183740 1:STN:280:DyaK2c3jvF2gtg%3D%3D 10.1016/S0344-0338(11)80843-5
    • Jaskiewicz K, Robson SC, Banach L (1993) Toxic hepatic injury is associated with proliferation of portal nerve fibers. Pathol Res Pract 189(10):1191-1194
    • (1993) Pathol Res Pract , vol.189 , Issue.10 , pp. 1191-1194
    • Jaskiewicz, K.1    Robson, S.C.2    Banach, L.3
  • 48
    • 0028292013 scopus 로고
    • Distribution of hepatic nerve fibers in liver diseases
    • 8063030 1:STN:280:DyaK2czktFCqsA%3D%3D 10.1159/000201156
    • Jaskiewicz K, Voigt MD, Robson SC (1994) Distribution of hepatic nerve fibers in liver diseases. Digestion 55(4):247-252
    • (1994) Digestion , vol.55 , Issue.4 , pp. 247-252
    • Jaskiewicz, K.1    Voigt, M.D.2    Robson, S.C.3
  • 49
    • 0032013558 scopus 로고    scopus 로고
    • PGE2 hyperpolarizes gallbladder neurons and inhibits synaptic potentials in gallbladder ganglia
    • 9530150 1:CAS:528:DyaK1cXitVCrsbs%3D
    • Jennings LJ, Mawe GM (1998) PGE2 hyperpolarizes gallbladder neurons and inhibits synaptic potentials in gallbladder ganglia. Am J Physiol 274(3 Pt 1):G493-G502
    • (1998) Am J Physiol , vol.274 , Issue.3 PART 1
    • Jennings, L.J.1    Mawe, G.M.2
  • 50
    • 80052381647 scopus 로고    scopus 로고
    • Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut
    • 21865643 1:CAS:528:DC%2BC3MXhtFOhsbnJ 10.1172/JCI58186
    • Joseph NM, He S, Quintana E, Kim YG, Nunez G, Morrison SJ (2011) Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut. J Clin Invest 121(9):3398-3411
    • (2011) J Clin Invest , vol.121 , Issue.9 , pp. 3398-3411
    • Joseph, N.M.1    He, S.2    Quintana, E.3    Kim, Y.G.4    Nunez, G.5    Morrison, S.J.6
  • 51
    • 12344318566 scopus 로고    scopus 로고
    • Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers
    • 15069095 1:CAS:528:DC%2BD2cXjvFyls7Y%3D 10.1152/jn.01097.2003
    • Kang YM, Bielefeldt K, Gebhart GF (2004) Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers. J Neurophysiol 91(5):1981-1989
    • (2004) J Neurophysiol , vol.91 , Issue.5 , pp. 1981-1989
    • Kang, Y.M.1    Bielefeldt, K.2    Gebhart, G.F.3
  • 52
    • 35248879789 scopus 로고    scopus 로고
    • Variations in inflammation and nerve fiber loss reflect different subsets of achalasia patients
    • 17950090 10.1016/j.jss.2007.03.050
    • Kilic A, Krasinskas AM, Owens SR, Luketich JD, Landreneau RJ, Schuchert MJ (2007) Variations in inflammation and nerve fiber loss reflect different subsets of achalasia patients. J Surg Res 143(1):177-182
    • (2007) J Surg Res , vol.143 , Issue.1 , pp. 177-182
    • Kilic, A.1    Krasinskas, A.M.2    Owens, S.R.3    Luketich, J.D.4    Landreneau, R.J.5    Schuchert, M.J.6
  • 53
    • 47649114091 scopus 로고    scopus 로고
    • Morphometric evaluation of oesophageal wall in patients with nutcracker oesophagus and ineffective oesophageal motility
    • 18452508 1:STN:280:DC%2BD1crisFSrsQ%3D%3D 10.1111/j.1365-2982.2008.01128. x
    • Kim HS, Park H, Lim JH, Choi SH, Park C, Lee SI, Conklin JL (2008) Morphometric evaluation of oesophageal wall in patients with nutcracker oesophagus and ineffective oesophageal motility. Neurogastroenterol Motil 20(8):869-876
    • (2008) Neurogastroenterol Motil , vol.20 , Issue.8 , pp. 869-876
    • Kim, H.S.1    Park, H.2    Lim, J.H.3    Choi, S.H.4    Park, C.5    Lee, S.I.6    Conklin, J.L.7
  • 54
    • 68249133724 scopus 로고    scopus 로고
    • Trinitrobenzenesulphonic acid colitis alters Na 1.8 channel expression in mouse dorsal root ganglia neurons
    • 10.1111/j.1365-2982.2009.01279.x 1:CAS:528:DC%2BD1MXhtVGis7%2FK
    • King DE, Macleod RJ, Vanner SJ (2009) Trinitrobenzenesulphonic acid colitis alters Na 1.8 channel expression in mouse dorsal root ganglia neurons. Neurogastroenterol Motil 21(8):e880-e864
    • (2009) Neurogastroenterol Motil , vol.21 , Issue.8
    • King, D.E.1    MacLeod, R.J.2    Vanner, S.J.3
  • 55
    • 79959836378 scopus 로고    scopus 로고
    • Colitis decreases mechanosensitive K2P channel expression and function in mouse colon sensory neurons
    • 21512155 1:CAS:528:DC%2BC3MXptlSgsLc%3D 10.1152/ajpgi.00417.2010
    • La JH, Gebhart GF (2011) Colitis decreases mechanosensitive K2P channel expression and function in mouse colon sensory neurons. Am J Physiol Gastrointest Liver Physiol 301(1):G165-G174
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301 , Issue.1
    • La, J.H.1    Gebhart, G.F.2
  • 56
    • 84911840045 scopus 로고
    • On the regeneration of preganglionic and of postganglionic visceral nerve fibres
    • 16992403 1:STN:280:DC%2BD2s%2FntFaqtA%3D%3D
    • Langley JN (1897) On the regeneration of preganglionic and of postganglionic visceral nerve fibres. J Physiol 22:215-2130
    • (1897) J Physiol , vol.22 , pp. 215-2130
    • Langley, J.N.1
  • 57
    • 80052361701 scopus 로고    scopus 로고
    • Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury
    • 21865647 1:CAS:528:DC%2BC3MXhtFOhsbnK 10.1172/JCI58200
    • Laranjeira C, Sandgren K, Kessaris N, Richardson W, Potocnik A, Vanden Berghe P, Pachnis V (2011) Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury. J Clin Invest 121(9):3412-3424
    • (2011) J Clin Invest , vol.121 , Issue.9 , pp. 3412-3424
    • Laranjeira, C.1    Sandgren, K.2    Kessaris, N.3    Richardson, W.4    Potocnik, A.5    Vanden Berghe, P.6    Pachnis, V.7
  • 58
    • 0026515675 scopus 로고
    • Disappearance of hepatic parenchymal nerves in human liver cirrhosis
    • 1531471 1:STN:280:DyaK387lsFGguw%3D%3D 10.1136/gut.33.1.87
    • Lee JA, Ahmed Q, Hines JE, Burt AD (1992) Disappearance of hepatic parenchymal nerves in human liver cirrhosis. Gut 33(1):87-91
    • (1992) Gut , vol.33 , Issue.1 , pp. 87-91
    • Lee, J.A.1    Ahmed, Q.2    Hines, J.E.3    Burt, A.D.4
  • 59
    • 84861197462 scopus 로고    scopus 로고
    • Colonic inflammation up-regulates voltage-gated sodium channels in bladder sensory neurons via activation of peripheral transient potential vanilloid 1 receptors
    • 22420642 10.1111/j.1365-2982.2012.01910.x 1:CAS:528:DC%2BC38XhtVOmtbnP e257
    • Lei Q, Malykhina AP (2012) Colonic inflammation up-regulates voltage-gated sodium channels in bladder sensory neurons via activation of peripheral transient potential vanilloid 1 receptors. Neurogastroenterol Motil 24(6):575-585 (e257)
    • (2012) Neurogastroenterol Motil , vol.24 , Issue.6 , pp. 575-585
    • Lei, Q.1    Malykhina, A.P.2
  • 60
    • 34547732522 scopus 로고    scopus 로고
    • The structural characteristics and expression of neuropeptides in the esophagus of patients with congenital esophageal atresia and tracheoesophageal fistula
    • 17706510 10.1016/j.jpedsurg.2007.03.050
    • Li K, Zheng S, Xiao X, Wang Q, Zhou Y, Chen L (2007) The structural characteristics and expression of neuropeptides in the esophagus of patients with congenital esophageal atresia and tracheoesophageal fistula. J Pediatr Surg 42(8):1433-1438
    • (2007) J Pediatr Surg , vol.42 , Issue.8 , pp. 1433-1438
    • Li, K.1    Zheng, S.2    Xiao, X.3    Wang, Q.4    Zhou, Y.5    Chen, L.6
  • 61
    • 11844249981 scopus 로고    scopus 로고
    • Neurogenic inflammation and pancreatitis
    • 15550764 10.1159/000082180 discussion 559-560
    • Liddle RA, Nathan JD (2004) Neurogenic inflammation and pancreatitis. Pancreatology 4(6):551-559 (discussion 559-560)
    • (2004) Pancreatology , vol.4 , Issue.6 , pp. 551-559
    • Liddle, R.A.1    Nathan, J.D.2
  • 63
    • 0037335602 scopus 로고    scopus 로고
    • Enhanced excitability of myenteric AH neurones in the inflamed guinea-pig distal colon
    • 12562910 1:CAS:528:DC%2BD3sXivFSrtbo%3D 10.1113/jphysiol.2002.035147
    • Linden DR, Sharkey KA, Mawe GM (2003) Enhanced excitability of myenteric AH neurones in the inflamed guinea-pig distal colon. J Physiol 547(Pt 2):589-601
    • (2003) J Physiol , vol.547 , Issue.PART 2 , pp. 589-601
    • Linden, D.R.1    Sharkey, K.A.2    Mawe, G.M.3
  • 65
    • 13444312103 scopus 로고    scopus 로고
    • Plasticity of the enteric nervous system during intestinal inflammation
    • 15670258 1:STN:280:DC%2BD2M%2FksVWqsg%3D%3D 10.1111/j.1365-2982.2004. 00607.x
    • Lomax AE, Fernandez E, Sharkey KA (2005) Plasticity of the enteric nervous system during intestinal inflammation. Neurogastroenterol Motil 17(1):4-15
    • (2005) Neurogastroenterol Motil , vol.17 , Issue.1 , pp. 4-15
    • Lomax, A.E.1    Fernandez, E.2    Sharkey, K.A.3
  • 66
    • 0031943087 scopus 로고    scopus 로고
    • Are giant ganglia a reliable marker of intestinal neuronal dysplasia type B (IND B)?
    • 9504853 1:STN:280:DyaK1c7mtlersw%3D%3D 10.1007/s004280050141
    • Lumb PD, Moore L (1998) Are giant ganglia a reliable marker of intestinal neuronal dysplasia type B (IND B)? Virchows Arch 432(2):103-106
    • (1998) Virchows Arch , vol.432 , Issue.2 , pp. 103-106
    • Lumb, P.D.1    Moore, L.2
  • 67
    • 33748484877 scopus 로고    scopus 로고
    • Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: Mechanism for pelvic organ cross-talk
    • 16961697 1:STN:280:DC%2BD28rjvVKrtA%3D%3D 10.1111/j.1365-2982.2006.00807. x
    • Malykhina AP, Qin C, Greenwood-van Meerveld B, Foreman RD, Lupu F, Akbarali HI (2006) Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk. Neurogastroenterol Motil 18(10):936-948
    • (2006) Neurogastroenterol Motil , vol.18 , Issue.10 , pp. 936-948
    • Malykhina, A.P.1    Qin, C.2    Greenwood-Van Meerveld, B.3    Foreman, R.D.4    Lupu, F.5    Akbarali, H.I.6
  • 68
    • 0033015309 scopus 로고    scopus 로고
    • Stromal mast cells and nerve fibers in various chronic liver diseases: Relevance to hepatic fibrosis
    • 10406261 1:STN:280:DyaK1Mzjt1yqtg%3D%3D 10.1111/j.1572-0241.1999.01232.x
    • Matsunaga Y, Kawasaki H, Terada T (1999) Stromal mast cells and nerve fibers in various chronic liver diseases: relevance to hepatic fibrosis. Am J Gastroenterol 94(7):1923-1932
    • (1999) Am J Gastroenterol , vol.94 , Issue.7 , pp. 1923-1932
    • Matsunaga, Y.1    Kawasaki, H.2    Terada, T.3
  • 69
    • 4444357719 scopus 로고    scopus 로고
    • Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human oesophagus
    • 15316415 1:CAS:528:DC%2BD2cXmslOnur4%3D 10.1097/00042737-200409000-00014
    • Matthews PJ, Aziz Q, Facer P, Davis JB, Thompson DG, Anand P (2004) Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human oesophagus. Eur J Gastroenterol Hepatol 16(9):897-902
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , Issue.9 , pp. 897-902
    • Matthews, P.J.1    Aziz, Q.2    Facer, P.3    Davis, J.B.4    Thompson, D.G.5    Anand, P.6
  • 70
    • 65349083130 scopus 로고    scopus 로고
    • Plasticity of enteric nerve functions in the inflamed and postinflamed gut
    • 19368664 1:STN:280:DC%2BD1Mzjs1SktA%3D%3D 10.1111/j.1365-2982.2009.01291. x
    • Mawe GM, Strong DS, Sharkey KA (2009) Plasticity of enteric nerve functions in the inflamed and postinflamed gut. Neurogastroenterol Motil 21(5):481-491
    • (2009) Neurogastroenterol Motil , vol.21 , Issue.5 , pp. 481-491
    • Mawe, G.M.1    Strong, D.S.2    Sharkey, K.A.3
  • 71
    • 26244434740 scopus 로고    scopus 로고
    • Response properties of the brainstem neurons of the cat following intra-esophageal acid-pepsin infusion
    • 16165290 1:CAS:528:DC%2BD2MXhtVymtr%2FE 10.1016/j.neuroscience.2005.07. 016
    • Medda BK, Sengupta JN, Lang IM, Shaker R (2005) Response properties of the brainstem neurons of the cat following intra-esophageal acid-pepsin infusion. Neuroscience 135(4):1285-1294
    • (2005) Neuroscience , vol.135 , Issue.4 , pp. 1285-1294
    • Medda, B.K.1    Sengupta, J.N.2    Lang, I.M.3    Shaker, R.4
  • 72
    • 0038416757 scopus 로고    scopus 로고
    • Nitrergic hyperinnervation in appendicitis and in appendices histologically classified as normal
    • 12708900
    • Nemeth L, Rolle U, Reen DJ, Puri P (2003) Nitrergic hyperinnervation in appendicitis and in appendices histologically classified as normal. Arch Pathol Lab Med 127(5):573-578
    • (2003) Arch Pathol Lab Med , vol.127 , Issue.5 , pp. 573-578
    • Nemeth, L.1    Rolle, U.2    Reen, D.J.3    Puri, P.4
  • 75
    • 0033057105 scopus 로고    scopus 로고
    • Oesophageal epithelial innervation in health and reflux oesophagitis
    • 10026314 1:STN:280:DyaK1M7lt1WhsA%3D%3D 10.1136/gut.44.3.317
    • Newton M, Kamm MA, Soediono PO, Milner P, Burnham WR, Burnstock G (1999) Oesophageal epithelial innervation in health and reflux oesophagitis. Gut 44(3):317-322
    • (1999) Gut , vol.44 , Issue.3 , pp. 317-322
    • Newton, M.1    Kamm, M.A.2    Soediono, P.O.3    Milner, P.4    Burnham, W.R.5    Burnstock, G.6
  • 76
    • 33846956144 scopus 로고    scopus 로고
    • Ileitis alters neuronal and enteroendocrine signalling in guinea pig distal colon
    • 16931576 10.1136/gut.2006.102780 1:CAS:528:DC%2BD2sXivF2gt70%3D
    • O'Hara JR, Lomax AE, Mawe GM, Sharkey KA (2007) Ileitis alters neuronal and enteroendocrine signalling in guinea pig distal colon. Gut 56(2):186-194
    • (2007) Gut , vol.56 , Issue.2 , pp. 186-194
    • O'Hara, J.R.1    Lomax, A.E.2    Mawe, G.M.3    Sharkey, K.A.4
  • 77
    • 0027186019 scopus 로고
    • Regional content of enteric substance P and vasoactive intestinal peptide during intestinal inflammation in the parasitized ferret
    • 7692345 1:CAS:528:DyaK3sXmtFyisro%3D 10.1016/0143-4179(93)90088-R
    • Palmer JM, Greenwood B (1993) Regional content of enteric substance P and vasoactive intestinal peptide during intestinal inflammation in the parasitized ferret. Neuropeptides 25(2):95-103
    • (1993) Neuropeptides , vol.25 , Issue.2 , pp. 95-103
    • Palmer, J.M.1    Greenwood, B.2
  • 78
    • 77956448154 scopus 로고    scopus 로고
    • Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways
    • 20501335 1:CAS:528:DC%2BC3cXhtFCmtbfO 10.1016/j.expneurol.2010.05.012
    • Pan XQ, Gonzalez JA, Chang S, Chacko S, Wein AJ, Malykhina AP (2010) Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways. Exp Neurol 225(2):262-273
    • (2010) Exp Neurol , vol.225 , Issue.2 , pp. 262-273
    • Pan, X.Q.1    Gonzalez, J.A.2    Chang, S.3    Chacko, S.4    Wein, A.J.5    Malykhina, A.P.6
  • 79
    • 33645240056 scopus 로고    scopus 로고
    • Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome
    • 16706815 10.1111/j.1440-1746.2005.04143.x
    • Park JH, Rhee PL, Kim HS, Lee JH, Kim YH, Kim JJ, Rhee JC (2006) Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome. J Gastroenterol Hepatol 21(1 Pt 1):71-78
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.1 PART 1 , pp. 71-78
    • Park, J.H.1    Rhee, P.L.2    Kim, H.S.3    Lee, J.H.4    Kim, Y.H.5    Kim, J.J.6    Rhee, J.C.7
  • 81
    • 67349124372 scopus 로고    scopus 로고
    • Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats
    • 19324074 1:CAS:528:DC%2BD1MXms1WjtL8%3D 10.1016/j.neuroscience.2009.03. 040
    • Peles S, Medda BK, Zhang Z, Banerjee B, Lehmann A, Shaker R, Sengupta JN (2009) Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats. Neuroscience 161(2):515-525
    • (2009) Neuroscience , vol.161 , Issue.2 , pp. 515-525
    • Peles, S.1    Medda, B.K.2    Zhang, Z.3    Banerjee, B.4    Lehmann, A.5    Shaker, R.6    Sengupta, J.N.7
  • 82
    • 80053563770 scopus 로고    scopus 로고
    • Decreased pain inhibition in irritable bowel syndrome depends on altered descending modulation and higher-order brain processes
    • 21889972 1:CAS:528:DC%2BC3MXht12gsrnP 10.1016/j.neuroscience.2011.08.040
    • Piche M, Bouin M, Arsenault M, Poitras P, Rainville P (2011) Decreased pain inhibition in irritable bowel syndrome depends on altered descending modulation and higher-order brain processes. Neuroscience 195:166-175
    • (2011) Neuroscience , vol.195 , pp. 166-175
    • Piche, M.1    Bouin, M.2    Arsenault, M.3    Poitras, P.4    Rainville, P.5
  • 83
    • 3042678052 scopus 로고    scopus 로고
    • Chemical mediators of gallbladder dysmotility
    • 15279583 1:CAS:528:DC%2BD2cXkvFOqsbk%3D 10.2174/0929867043364955
    • Pozo MJ, Camello PJ, Mawe GM (2004) Chemical mediators of gallbladder dysmotility. Curr Med Chem 11(13):1801-1812
    • (2004) Curr Med Chem , vol.11 , Issue.13 , pp. 1801-1812
    • Pozo, M.J.1    Camello, P.J.2    Mawe, G.M.3
  • 84
    • 79951806353 scopus 로고    scopus 로고
    • Spinal toll like receptor 3 is involved in chronic pancreatitis-induced mechanical allodynia of rat
    • 21342497 1:CAS:528:DC%2BC3MXjtl2murk%3D 10.1186/1744-8069-7-15
    • Qian NS, Liao YH, Feng QX, Tang Y, Dou KF, Tao KS (2011) Spinal toll like receptor 3 is involved in chronic pancreatitis-induced mechanical allodynia of rat. Mol Pain 7:15
    • (2011) Mol Pain , vol.7 , pp. 15
    • Qian, N.S.1    Liao, Y.H.2    Feng, Q.X.3    Tang, Y.4    Dou, K.F.5    Tao, K.S.6
  • 85
    • 41549115396 scopus 로고    scopus 로고
    • Intraesophageal chemicals enhance responsiveness of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats
    • 18187515 1:CAS:528:DC%2BD1cXjsFCisb4%3D 10.1152/ajpgi.00477.2007
    • Qin C, Farber JP, Foreman RD (2008) Intraesophageal chemicals enhance responsiveness of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats. Am J Physiol Gastrointest Liver Physiol 294(3):G708-G716
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , Issue.3
    • Qin, C.1    Farber, J.P.2    Foreman, R.D.3
  • 86
    • 0033678445 scopus 로고    scopus 로고
    • Substance P (neurokinin-1) and neurokinin A (neurokinin-2) receptor gene and protein expression in the healthy and inflamed human intestine
    • 11073811 1:CAS:528:DC%2BD3cXosFyhsr0%3D 10.1016/S0002-9440(10)64789-X
    • Renzi D, Pellegrini B, Tonelli F, Surrenti C, Calabro A (2000) Substance P (neurokinin-1) and neurokinin A (neurokinin-2) receptor gene and protein expression in the healthy and inflamed human intestine. Am J Pathol 157(5):1511-1522
    • (2000) Am J Pathol , vol.157 , Issue.5 , pp. 1511-1522
    • Renzi, D.1    Pellegrini, B.2    Tonelli, F.3    Surrenti, C.4    Calabro, A.5
  • 87
    • 51049102605 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines
    • 18781096 1:CAS:528:DC%2BD1cXhtFKhur7F 10.1159/000152942
    • Rosso M, Robles-Frias MJ, Covenas R, Salinas-Martin MV, Munoz M (2008) The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines. Tumour Biol 29(4):245-254
    • (2008) Tumour Biol , vol.29 , Issue.4 , pp. 245-254
    • Rosso, M.1    Robles-Frias, M.J.2    Covenas, R.3    Salinas-Martin, M.V.4    Munoz, M.5
  • 88
    • 7044253553 scopus 로고    scopus 로고
    • Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression
    • 15447763 10.1111/j.1572-0241.2004.40174.x
    • Sarkar S, Thompson DG, Woolf CJ, Hobson AR, Millane T, Aziz Q (2004) Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression. Am J Gastroenterol 99(10):1998-2006
    • (2004) Am J Gastroenterol , vol.99 , Issue.10 , pp. 1998-2006
    • Sarkar, S.1    Thompson, D.G.2    Woolf, C.J.3    Hobson, A.R.4    Millane, T.5    Aziz, Q.6
  • 89
    • 34247183551 scopus 로고    scopus 로고
    • Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione
    • 17408650 1:CAS:528:DC%2BD2sXlslKrurg%3D 10.1053/j.gastro.2007.01.051
    • Savidge TC, Newman P, Pothoulakis C, Ruhl A, Neunlist M, Bourreille A, Hurst R, Sofroniew MV (2007) Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione. Gastroenterology 132(4):1344-1358
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1344-1358
    • Savidge, T.C.1    Newman, P.2    Pothoulakis, C.3    Ruhl, A.4    Neunlist, M.5    Bourreille, A.6    Hurst, R.7    Sofroniew, M.V.8
  • 90
    • 0027299956 scopus 로고
    • Parenchymal innervation of normal and cirrhotic human liver: A light and electron microscopic study using monoclonal antibodies against the neural cell-adhesion molecule
    • 8315280 1:STN:280:DyaK3szgtFCnuw%3D%3D 10.1177/41.6.8315280
    • Scoazec JY, Racine L, Couvelard A, Moreau A, Flejou JF, Bernuau D, Feldmann G (1993) Parenchymal innervation of normal and cirrhotic human liver: a light and electron microscopic study using monoclonal antibodies against the neural cell-adhesion molecule. J Histochem Cytochem 41(6):899-908
    • (1993) J Histochem Cytochem , vol.41 , Issue.6 , pp. 899-908
    • Scoazec, J.Y.1    Racine, L.2    Couvelard, A.3    Moreau, A.4    Flejou, J.F.5    Bernuau, D.6    Feldmann, G.7
  • 91
    • 8844234236 scopus 로고    scopus 로고
    • Electroesophagogram in gastroesophageal reflux disease with a new theory on the pathogenesis of its electric changes
    • 15462680 10.1186/1471-2482-4-13
    • Shafik A, El-Sibai O, Shafik I, Shafik A (2004) Electroesophagogram in gastroesophageal reflux disease with a new theory on the pathogenesis of its electric changes. BMC Surg 4:13
    • (2004) BMC Surg , vol.4 , pp. 13
    • Shafik, A.1    El-Sibai, O.2    Shafik, I.3    Shafik, A.4
  • 92
    • 77955440269 scopus 로고    scopus 로고
    • Evidence for neurotrophic factors associating with TRPV1 gene expression in the inflamed human esophagus
    • 20518854 1:CAS:528:DC%2BC3cXhtFKjt7fK 10.1111/j.1365-2982.2010.01530.x e252
    • Shieh KR, Yi CH, Liu TT, Tseng HL, Ho HC, Hsieh HT, Chen CL (2010) Evidence for neurotrophic factors associating with TRPV1 gene expression in the inflamed human esophagus. Neurogastroenterol Motil 22(9):971-977 (e252)
    • (2010) Neurogastroenterol Motil , vol.22 , Issue.9 , pp. 971-977
    • Shieh, K.R.1    Yi, C.H.2    Liu, T.T.3    Tseng, H.L.4    Ho, H.C.5    Hsieh, H.T.6    Chen, C.L.7
  • 94
    • 65449125951 scopus 로고    scopus 로고
    • Post inflammatory damage to the enteric nervous system in diverticular disease and its relationship to symptoms
    • 10.1111/j.1365-2982.2009.01308.x
    • Simpson J, Sundler F, Humes DJ, Jenkins D, Scholefield JH, Spiller RC (2009) Post inflammatory damage to the enteric nervous system in diverticular disease and its relationship to symptoms. Neurogastroenterol Motil 21(8):e847-e858
    • (2009) Neurogastroenterol Motil , vol.21 , Issue.8
    • Simpson, J.1    Sundler, F.2    Humes, D.J.3    Jenkins, D.4    Scholefield, J.H.5    Spiller, R.C.6
  • 95
    • 33846791296 scopus 로고    scopus 로고
    • Neuroimmune link in the mucosa of chronic gastritis with Helicobacter pylori infection
    • 16983504 1:STN:280:DC%2BD2s%2FgsFOqtg%3D%3D 10.1007/s10620-006-9085-5
    • Sipos G, Altdorfer K, Pongor E, Chen LP, Feher E (2006) Neuroimmune link in the mucosa of chronic gastritis with Helicobacter pylori infection. Dig Dis Sci 51(10):1810-1817
    • (2006) Dig Dis Sci , vol.51 , Issue.10 , pp. 1810-1817
    • Sipos, G.1    Altdorfer, K.2    Pongor, E.3    Chen, L.P.4    Feher, E.5
  • 96
    • 52049100155 scopus 로고    scopus 로고
    • Correlation and immunolocalization of substance P nerve fibers and activated immune cells in human chronic gastritis
    • 10.1002/ar.20737
    • Sipos G, Sipos P, Altdorfer K, Pongor E, Feher E (2008) Correlation and immunolocalization of substance P nerve fibers and activated immune cells in human chronic gastritis. Anat Rec (Hoboken) 291(9):1140-1148
    • (2008) Anat Rec (Hoboken) , vol.291 , Issue.9 , pp. 1140-1148
    • Sipos, G.1    Sipos, P.2    Altdorfer, K.3    Pongor, E.4    Feher, E.5
  • 97
    • 0036929407 scopus 로고    scopus 로고
    • Changes in the colonic enteric nervous system in rats with chemically induced colon dysplasia and carcinoma
    • 12546527 10.1080/02841860214957
    • Sitohy B, El-Salhy M (2002) Changes in the colonic enteric nervous system in rats with chemically induced colon dysplasia and carcinoma. Acta Oncol 41(6):543-549
    • (2002) Acta Oncol , vol.41 , Issue.6 , pp. 543-549
    • Sitohy, B.1    El-Salhy, M.2
  • 98
    • 0035977427 scopus 로고    scopus 로고
    • Mast cells differentially express and release active high molecular weight neurotrophins
    • 11750074 1:CAS:528:DC%2BD3MXpt1amtb0%3D 10.1016/S0169-328X(01)00314-X
    • Skaper SD, Pollock M, Facci L (2001) Mast cells differentially express and release active high molecular weight neurotrophins. Brain Res Mol Brain Res 97(2):177-185
    • (2001) Brain Res Mol Brain Res , vol.97 , Issue.2 , pp. 177-185
    • Skaper, S.D.1    Pollock, M.2    Facci, L.3
  • 99
    • 42749089449 scopus 로고    scopus 로고
    • Inflammation causes expression of NGF in epithelial cells of the rat colon
    • 18377896 1:CAS:528:DC%2BD1cXlsF2qtL8%3D 10.1016/j.expneurol.2008.01.028
    • Stanzel RD, Lourenssen S, Blennerhassett MG (2008) Inflammation causes expression of NGF in epithelial cells of the rat colon. Exp Neurol 211(1):203-213
    • (2008) Exp Neurol , vol.211 , Issue.1 , pp. 203-213
    • Stanzel, R.D.1    Lourenssen, S.2    Blennerhassett, M.G.3
  • 100
    • 0031854284 scopus 로고    scopus 로고
    • Peptidergic nerve fibres in the human liver
    • 9717562 1:CAS:528:DyaK1cXkvFCit7s%3D 10.1016/S0065-1281(98)80011-1
    • Stoyanova II, Gulubova MV (1998) Peptidergic nerve fibres in the human liver. Acta Histochem 100(3):245-256
    • (1998) Acta Histochem , vol.100 , Issue.3 , pp. 245-256
    • Stoyanova, I.I.1    Gulubova, M.V.2
  • 101
    • 34249700182 scopus 로고    scopus 로고
    • Autoimmune disease and innervation
    • 17517488 1:CAS:528:DC%2BD2sXmtVOmtbw%3D 10.1016/j.bbi.2007.04.005
    • Straub RH (2007) Autoimmune disease and innervation. Brain Behav Immun 21(5):528-534
    • (2007) Brain Behav Immun , vol.21 , Issue.5 , pp. 528-534
    • Straub, R.H.1
  • 103
    • 14944354848 scopus 로고    scopus 로고
    • Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach
    • 15758172 1:CAS:528:DC%2BD2MXis1ygsL4%3D 10.1523/JNEUROSCI.2894-04.2005
    • Sugiura T, Dang K, Lamb K, Bielefeldt K, Gebhart GF (2005) Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach. J Neurosci 25(10):2617-2627
    • (2005) J Neurosci , vol.25 , Issue.10 , pp. 2617-2627
    • Sugiura, T.1    Dang, K.2    Lamb, K.3    Bielefeldt, K.4    Gebhart, G.F.5
  • 104
    • 0033198279 scopus 로고    scopus 로고
    • Direct neurite-mast cell communication in vitro occurs via the neuropeptide substance P
    • 10452975 1:CAS:528:DyaK1MXls1Krs7s%3D
    • Suzuki R, Furuno T, McKay DM, Wolvers D, Teshima R, Nakanishi M, Bienenstock J (1999) Direct neurite-mast cell communication in vitro occurs via the neuropeptide substance P. J Immunol 163(5):2410-2415
    • (1999) J Immunol , vol.163 , Issue.5 , pp. 2410-2415
    • Suzuki, R.1    Furuno, T.2    McKay, D.M.3    Wolvers, D.4    Teshima, R.5    Nakanishi, M.6    Bienenstock, J.7
  • 105
    • 79953138460 scopus 로고    scopus 로고
    • Modulation of visceral hypersensitivity by glial cell line-derived neurotrophic factor family receptor and alpha;-3 in colorectal afferents
    • 21193524 1:CAS:528:DC%2BC3MXjs1Grtrk%3D 10.1152/ajpgi.00456.2010
    • Tanaka T, Shinoda M, Feng B, Albers KM, Gebhart GF (2011) Modulation of visceral hypersensitivity by glial cell line-derived neurotrophic factor family receptor and alpha;-3 in colorectal afferents. Am J Physiol Gastrointest Liver Physiol 300(3):G418-G424
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.300 , Issue.3
    • Tanaka, T.1    Shinoda, M.2    Feng, B.3    Albers, K.M.4    Gebhart, G.F.5
  • 106
    • 0035117383 scopus 로고    scopus 로고
    • S-100-positive nerve fibers in hepatocellular carcinoma and intrahepatic cholangiocarcinoma: An immunohistochemical study
    • 11169146 1:STN:280:DC%2BD3M3hsVKiuw%3D%3D 10.1046/j.1440-1827.2001.01172. x
    • Terada T, Matsunaga Y (2001) S-100-positive nerve fibers in hepatocellular carcinoma and intrahepatic cholangiocarcinoma: an immunohistochemical study. Pathol Int 51(2):89-93
    • (2001) Pathol Int , vol.51 , Issue.2 , pp. 89-93
    • Terada, T.1    Matsunaga, Y.2
  • 107
    • 0017053513 scopus 로고
    • Some aspects of human and canine macroscopic pancreas innervation
    • 998597 1:STN:280:DyaE2s%2FmtlWjsQ%3D%3D
    • Tiscornia OM, Martinez JL, Sarles H (1976) Some aspects of human and canine macroscopic pancreas innervation. Am J Gastroenterol 66(4):353-361
    • (1976) Am J Gastroenterol , vol.66 , Issue.4 , pp. 353-361
    • Tiscornia, O.M.1    Martinez, J.L.2    Sarles, H.3
  • 108
    • 0036893131 scopus 로고    scopus 로고
    • Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome
    • 12454854 10.1053/gast.2002.37059
    • Tornblom H, Lindberg G, Nyberg B, Veress B (2002) Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome. Gastroenterology 123(6):1972-1979
    • (2002) Gastroenterology , vol.123 , Issue.6 , pp. 1972-1979
    • Tornblom, H.1    Lindberg, G.2    Nyberg, B.3    Veress, B.4
  • 111
    • 0036697157 scopus 로고    scopus 로고
    • Enteric nervous plasticity and development: Dependence on neurotrophic factors
    • 10.1007/s005350200093
    • von Boyen GB, Reinshagen M, Steinkamp M, Adler G, Kirsch J (2002) Enteric nervous plasticity and development: dependence on neurotrophic factors. J Gastroenterol 37(8):583-588
    • (2002) J Gastroenterol , vol.37 , Issue.8 , pp. 583-588
    • Von Boyen, G.B.1    Reinshagen, M.2    Steinkamp, M.3    Adler, G.4    Kirsch, J.5
  • 113
    • 34548829769 scopus 로고    scopus 로고
    • Alternation of substance P-containing neural pathways in a rat model of irritable bowel syndrome with rectal distension
    • 17054583 1:CAS:528:DC%2BD28Xhtlans7bL 10.1111/j.1443-9573.2006.00273.x
    • Wang WF, Yang YS, Peng LH, Sun G (2006) Alternation of substance P-containing neural pathways in a rat model of irritable bowel syndrome with rectal distension. Chin J Dig Dis 7(4):211-218
    • (2006) Chin J Dig Dis , vol.7 , Issue.4 , pp. 211-218
    • Wang, W.F.1    Yang, Y.S.2    Peng, L.H.3    Sun, G.4
  • 114
    • 0036788082 scopus 로고    scopus 로고
    • Beyond neurons: Evidence that immune and glial cells contribute to pathological pain states
    • 12270950 1:CAS:528:DC%2BD38Xot1Ggu74%3D
    • Watkins LR, Maier SF (2002) Beyond neurons: evidence that immune and glial cells contribute to pathological pain states. Physiol Rev 82(4):981-1011
    • (2002) Physiol Rev , vol.82 , Issue.4 , pp. 981-1011
    • Watkins, L.R.1    Maier, S.F.2
  • 115
    • 77949290638 scopus 로고    scopus 로고
    • Diverticular disease is associated with an enteric neuropathy as revealed by morphometric analysis
    • 20040058 1:STN:280:DC%2BC3c3kslertQ%3D%3D 10.1111/j.1365-2982.2009.01445. x e493-e404
    • Wedel T, Busing V, Heinrichs G, Nohroudi K, Bruch HP, Roblick UJ, Bottner M (2010) Diverticular disease is associated with an enteric neuropathy as revealed by morphometric analysis. Neurogastroenterol Motil 22(4):407-414 e493-e404
    • (2010) Neurogastroenterol Motil , vol.22 , Issue.4 , pp. 407-414
    • Wedel, T.1    Busing, V.2    Heinrichs, G.3    Nohroudi, K.4    Bruch, H.P.5    Roblick, U.J.6    Bottner, M.7
  • 116
    • 84863839647 scopus 로고    scopus 로고
    • Nerve growth factor content is increased in the rectal mucosa of children with diarrhea-predominant irritable bowel syndrome
    • 22625872 1:CAS:528:DC%2BC38XhsFWkurzN 10.1111/j.1365-2982.2012.01933.x e347
    • Willot S, Gauthier C, Patey N, Faure C (2012) Nerve growth factor content is increased in the rectal mucosa of children with diarrhea-predominant irritable bowel syndrome. Neurogastroenterol Motil 24(8):734-739 (e347)
    • (2012) Neurogastroenterol Motil , vol.24 , Issue.8 , pp. 734-739
    • Willot, S.1    Gauthier, C.2    Patey, N.3    Faure, C.4
  • 118
    • 67650088003 scopus 로고    scopus 로고
    • TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus
    • 19423751 1:CAS:528:DC%2BD1MXovVKjtbs%3D 10.1152/ajpgi.00068.2009
    • Yu S, Gao G, Peterson BZ, Ouyang A (2009) TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol 297(1):G34-G42
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.297 , Issue.1
    • Yu, S.1    Gao, G.2    Peterson, B.Z.3    Ouyang, A.4
  • 119
    • 79954511154 scopus 로고    scopus 로고
    • Inhibition of gastric motility by hyperglycemia is mediated by nodose ganglia KATP channels
    • 21193530 1:CAS:528:DC%2BC3MXjs1Grtro%3D 10.1152/ajpgi.00493.2010
    • Zhou SY, Lu Y, Song I, Owyang C (2011) Inhibition of gastric motility by hyperglycemia is mediated by nodose ganglia KATP channels. Am J Physiol Gastrointest Liver Physiol 300(3):G394-G400
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.300 , Issue.3
    • Zhou, S.Y.1    Lu, Y.2    Song, I.3    Owyang, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.