메뉴 건너뛰기




Volumn 294, Issue 3, 2008, Pages

Intraesophageal chemicals enhance responsiveness of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats

Author keywords

Esophagitis; Gastroesophageal reflux; Heartburn; Noncardiac chest pain; Visceral hypersensitivity

Indexed keywords

BRADYKININ; CAPSAICIN; HYDROCHLORIC ACID; IRRITANT AGENT;

EID: 41549115396     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00477.2007     Document Type: Article
Times cited : (16)

References (56)
  • 1
    • 0035313433 scopus 로고    scopus 로고
    • Vertebrate cranial placodes. I. Embryonic induction
    • Baker CV, Bronner-Fraser M. Vertebrate cranial placodes. I. Embryonic induction. Dev Biol 232: 1-61, 2001.
    • (2001) Dev Biol , vol.232 , pp. 1-61
    • Baker, C.V.1    Bronner-Fraser, M.2
  • 2
    • 0033975659 scopus 로고    scopus 로고
    • Acute effects of capsaicin on gastrointestinal vagal afferents
    • Blackshaw LA, Page AJ, Partosoedarso ER. Acute effects of capsaicin on gastrointestinal vagal afferents. Neuroscience 96: 407-416, 2000.
    • (2000) Neuroscience , vol.96 , pp. 407-416
    • Blackshaw, L.A.1    Page, A.J.2    Partosoedarso, E.R.3
  • 3
    • 0033093162 scopus 로고    scopus 로고
    • Effects of inflammatory mediators on gut sensitivity
    • Bueno L, Fioramonti J. Effects of inflammatory mediators on gut sensitivity. Can J Gastroenterol 13, Suppl A: 42A-46A, 1999.
    • (1999) Can J Gastroenterol , vol.13 , Issue.SUPPL. A
    • Bueno, L.1    Fioramonti, J.2
  • 4
    • 0034926291 scopus 로고    scopus 로고
    • The vanilloid receptor: A molecular gateway to the pain pathway
    • Caterina MJ, Julius D. The vanilloid receptor: a molecular gateway to the pain pathway. Annu Rev Neurosci 24: 487-517, 2001.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 487-517
    • Caterina, M.J.1    Julius, D.2
  • 5
    • 3242806675 scopus 로고    scopus 로고
    • Gastroesophageal reflux disease, Barrett esophagus, and esophageal adenocarcinoma
    • Chang JT, Katzka DA. Gastroesophageal reflux disease, Barrett esophagus, and esophageal adenocarcinoma. Arch Intern Med 164: 1482-1488, 2004.
    • (2004) Arch Intern Med , vol.164 , pp. 1482-1488
    • Chang, J.T.1    Katzka, D.A.2
  • 6
    • 0347504835 scopus 로고    scopus 로고
    • TRP channels as cellular sensors
    • Clapham DE. TRP channels as cellular sensors. Nature 426: 517-524, 2003.
    • (2003) Nature , vol.426 , pp. 517-524
    • Clapham, D.E.1
  • 7
    • 0032857476 scopus 로고    scopus 로고
    • Intraesophageal pH monitoring during acid infusion in patients with systemic sclerosis
    • Carola F, Bianchi PA, Basilisco G. Intraesophageal pH monitoring during acid infusion in patients with systemic sclerosis. Dig Dis Sci 44: 1716-1720, 1999.
    • (1999) Dig Dis Sci , vol.44 , pp. 1716-1720
    • Carola, F.1    Bianchi, P.A.2    Basilisco, G.3
  • 8
    • 0030922235 scopus 로고    scopus 로고
    • Acid infusion does not affect intraesophageal balloon distension-induced sensory and pain thresholds
    • Devault KR. Acid infusion does not affect intraesophageal balloon distension-induced sensory and pain thresholds. Am J Gastroenterol 92: 947-949, 1997.
    • (1997) Am J Gastroenterol , vol.92 , pp. 947-949
    • Devault, K.R.1
  • 9
    • 0034810084 scopus 로고    scopus 로고
    • Vagal afferent input determines the volume dependence of rat esophageal motility patterns
    • Dong H, Loomis CW, Bieger D. Vagal afferent input determines the volume dependence of rat esophageal motility patterns. Am J Physiol Gastrointest Liver Physiol 281: G44-G53, 2001.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Dong, H.1    Loomis, C.W.2    Bieger, D.3
  • 11
    • 0027340032 scopus 로고
    • Characterization of responses of T2-T4 spinal cord neurons to esophageal distension in the rat
    • Euchner-Wamser I, Sengupta JN, Gebhart GF, Meller ST. Characterization of responses of T2-T4 spinal cord neurons to esophageal distension in the rat. J Neurophysiol 69: 868-883, 1993.
    • (1993) J Neurophysiol , vol.69 , pp. 868-883
    • Euchner-Wamser, I.1    Sengupta, J.N.2    Gebhart, G.F.3    Meller, S.T.4
  • 12
    • 0031760739 scopus 로고    scopus 로고
    • Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans
    • Fass R, Naliboff B, Higa L, Johnson C, Kodner A, Munakata J, Ngo J, Mayer EA. Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology 115: 1363-1373, 1998.
    • (1998) Gastroenterology , vol.115 , pp. 1363-1373
    • Fass, R.1    Naliboff, B.2    Higa, L.3    Johnson, C.4    Kodner, A.5    Munakata, J.6    Ngo, J.7    Mayer, E.A.8
  • 13
    • 0033032020 scopus 로고    scopus 로고
    • Mechanisms of cardiac pain
    • Foreman RD. Mechanisms of cardiac pain. Annu Rev Physiol 61: 143-167, 1999.
    • (1999) Annu Rev Physiol , vol.61 , pp. 143-167
    • Foreman, R.D.1
  • 14
    • 0026728501 scopus 로고
    • Viscerosomatic convergence onto feline spinal neurons from esophagus, heart and somatic fields: Effects of inflammation
    • Garrison DW, Chandler MJ, Foreman RD. Viscerosomatic convergence onto feline spinal neurons from esophagus, heart and somatic fields: effects of inflammation. Pain 49: 373-382, 1992.
    • (1992) Pain , vol.49 , pp. 373-382
    • Garrison, D.W.1    Chandler, M.J.2    Foreman, R.D.3
  • 15
    • 41549092466 scopus 로고    scopus 로고
    • Visceral pain and visceral hypersensitivity
    • edited by Flor H, Kalso E, and Dostrovsky JO. Seattle, WA: International Association for the Study of Pain
    • Gebhart GF, Bielefeldt K, Dang K, Xu L, Jones C 3rd, Lam KR. Visceral pain and visceral hypersensitivity. In: Proceedings of the 11th World Congress on Pain, edited by Flor H, Kalso E, and Dostrovsky JO. Seattle, WA: International Association for the Study of Pain, 2006, p. 285-300.
    • (2006) Proceedings of the 11th World Congress on Pain , pp. 285-300
    • Gebhart, G.F.1    Bielefeldt, K.2    Dang, K.3    Xu, L.4    Jones 3rd, C.5    Lam, K.R.6
  • 16
    • 0023619783 scopus 로고
    • Salivary response to esophageal acid in normal subjects and patients with reflux esophagitis
    • Helm JF, Dodds WJ, Hogan WJ. Salivary response to esophageal acid in normal subjects and patients with reflux esophagitis. Gastroenterology 93: 1393-1397, 1987.
    • (1987) Gastroenterology , vol.93 , pp. 1393-1397
    • Helm, J.F.1    Dodds, W.J.2    Hogan, W.J.3
  • 17
    • 1642410796 scopus 로고    scopus 로고
    • Brain processing of esophageal sensation in health and disease
    • Hobson AR, Aziz Q. Brain processing of esophageal sensation in health and disease. Gastroenterol Clin North Am 33: 69-91, 2004.
    • (2004) Gastroenterol Clin North Am , vol.33 , pp. 69-91
    • Hobson, A.R.1    Aziz, Q.2
  • 19
    • 0035840835 scopus 로고    scopus 로고
    • Gastrointestinal afferents as targets of novel drugs for the treatment of functional bowel disorders and visceral pain
    • Holzer P. Gastrointestinal afferents as targets of novel drugs for the treatment of functional bowel disorders and visceral pain. Eur J Pharmacol 429: 177-193, 2001.
    • (2001) Eur J Pharmacol , vol.429 , pp. 177-193
    • Holzer, P.1
  • 20
    • 0033826076 scopus 로고    scopus 로고
    • Intraesophageal acid perfusion sensitizes the esophagus to mechanical distension: A Barostat study
    • Hu WH, Martin CJ, Talley NJ. Intraesophageal acid perfusion sensitizes the esophagus to mechanical distension: a Barostat study. Am J Gastroenterol 95: 2189-2194, 2000.
    • (2000) Am J Gastroenterol , vol.95 , pp. 2189-2194
    • Hu, W.H.1    Martin, C.J.2    Talley, N.J.3
  • 21
    • 0028962977 scopus 로고
    • Prevalence of symptoms suggestive of gastro-oesophageal reflux disease in an adult population
    • Isolauri J, Laippala P. Prevalence of symptoms suggestive of gastro-oesophageal reflux disease in an adult population. Ann Med 27: 67-70, 1995.
    • (1995) Ann Med , vol.27 , pp. 67-70
    • Isolauri, J.1    Laippala, P.2
  • 22
    • 0034611432 scopus 로고    scopus 로고
    • Johanson JF. Epidemiology of esophageal and supraesophageal reflux injuries. Am J Med 108, Suppl 4a: 99S-103S, 2000.
    • Johanson JF. Epidemiology of esophageal and supraesophageal reflux injuries. Am J Med 108, Suppl 4a: 99S-103S, 2000.
  • 23
    • 0034533705 scopus 로고    scopus 로고
    • The prevalence of gastro-oesophageal reflux symptoms in a UK population and the consultation behaviour of patients with these symptoms
    • Kennedy T, Jones R. The prevalence of gastro-oesophageal reflux symptoms in a UK population and the consultation behaviour of patients with these symptoms. Aliment Pharmacol Ther 14: 1589-1594, 2000.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 1589-1594
    • Kennedy, T.1    Jones, R.2
  • 24
    • 0030931230 scopus 로고    scopus 로고
    • Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota
    • Locke GR 3rd, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ 3rd. Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology 112: 1448-1456, 1997.
    • (1997) Gastroenterology , vol.112 , pp. 1448-1456
    • Locke 3rd, G.R.1    Talley, N.J.2    Fett, S.L.3    Zinsmeister, A.R.4    Melton 3rd, L.J.5
  • 26
    • 0026719837 scopus 로고
    • Mechanisms of esophageal pain
    • Lynn RB. Mechanisms of esophageal pain. Am J Med 92: 11S-19S, 1992.
    • (1992) Am J Med , vol.92
    • Lynn, R.B.1
  • 28
    • 26244434740 scopus 로고    scopus 로고
    • Response properties of the brainstem neurons of the cat following intra-esophageal acid-pepsin infusion
    • Medda BK, Sengupta JN, Lang IM, Shaker R. Response properties of the brainstem neurons of the cat following intra-esophageal acid-pepsin infusion. Neuroscience 135: 1285-1294, 2005.
    • (2005) Neuroscience , vol.135 , pp. 1285-1294
    • Medda, B.K.1    Sengupta, J.N.2    Lang, I.M.3    Shaker, R.4
  • 29
    • 0028926481 scopus 로고
    • Sensitization to painful distension and abnormal sensory perception in the esophagus
    • Mehta AJ, De Caestecker JS, Camm AJ, Northfield TC. Sensitization to painful distension and abnormal sensory perception in the esophagus. Gastroenterology 108: 311-319, 1995.
    • (1995) Gastroenterology , vol.108 , pp. 311-319
    • Mehta, A.J.1    De Caestecker, J.S.2    Camm, A.J.3    Northfield, T.C.4
  • 30
    • 0024448285 scopus 로고
    • Cytoarchitectonic organization of the spinal cord in the rat. II. The cervical and upper thoracic cord
    • Molander C, Xu Q, Rivero-Melian C, Grant G. Cytoarchitectonic organization of the spinal cord in the rat. II. The cervical and upper thoracic cord. J Comp Neurol 289: 375-385, 1989.
    • (1989) J Comp Neurol , vol.289 , pp. 375-385
    • Molander, C.1    Xu, Q.2    Rivero-Melian, C.3    Grant, G.4
  • 31
    • 8844265310 scopus 로고    scopus 로고
    • Prevalence of gastro-oesophageal reflux symptoms and the influence of age and sex
    • Nilsson M, Johnsen R, Ye W, Hveem K, Lagergren J. Prevalence of gastro-oesophageal reflux symptoms and the influence of age and sex. Scand J Gastroenterol 39: 1040-1045, 2004.
    • (2004) Scand J Gastroenterol , vol.39 , pp. 1040-1045
    • Nilsson, M.1    Johnsen, R.2    Ye, W.3    Hveem, K.4    Lagergren, J.5
  • 32
    • 1642321714 scopus 로고    scopus 로고
    • Esophageal perception and noncardiac chest pain
    • Orlando RC. Esophageal perception and noncardiac chest pain. Gastroenterol Clin North Am 33: 25-33, 2004.
    • (2004) Gastroenterol Clin North Am , vol.33 , pp. 25-33
    • Orlando, R.C.1
  • 34
    • 0036092823 scopus 로고    scopus 로고
    • Vagal mechanoreceptors and chemoreceptors in mouse stomach and esophagus
    • Page AJ, Martin CM, Blackshaw LA. Vagal mechanoreceptors and chemoreceptors in mouse stomach and esophagus. J Neurophysiol 87: 2095-2103, 2002.
    • (2002) J Neurophysiol , vol.87 , pp. 2095-2103
    • Page, A.J.1    Martin, C.M.2    Blackshaw, L.A.3
  • 35
    • 0030693341 scopus 로고    scopus 로고
    • Vagal efferent fibre responses to gastric and oesophageal mechanical and chemical stimuli in the ferret
    • Partosoedarso ER, Blackshaw LA. Vagal efferent fibre responses to gastric and oesophageal mechanical and chemical stimuli in the ferret. J Auton Nerv Syst 66: 169-178, 1997.
    • (1997) J Auton Nerv Syst , vol.66 , pp. 169-178
    • Partosoedarso, E.R.1    Blackshaw, L.A.2
  • 36
    • 0345724837 scopus 로고    scopus 로고
    • Afferent pathways and responses of T3-T4 spinal neurons to cervical and thoracic esophageal distensions in rats
    • Qin C, Chandler MJ, Foreman RD. Afferent pathways and responses of T3-T4 spinal neurons to cervical and thoracic esophageal distensions in rats. Auton Neurosci 109: 10-20, 2003.
    • (2003) Auton Neurosci , vol.109 , pp. 10-20
    • Qin, C.1    Chandler, M.J.2    Foreman, R.D.3
  • 37
    • 4644266599 scopus 로고    scopus 로고
    • Responses and afferent pathways of C1-C2 spinal neurons to cervical and thoracic esophageal stimulation in rats
    • Qin C, Chandler MJ, Jou CJ, Foreman RD. Responses and afferent pathways of C1-C2 spinal neurons to cervical and thoracic esophageal stimulation in rats. J Neurophysiol 91: 2227-2235, 2004.
    • (2004) J Neurophysiol , vol.91 , pp. 2227-2235
    • Qin, C.1    Chandler, M.J.2    Jou, C.J.3    Foreman, R.D.4
  • 38
    • 41549113551 scopus 로고    scopus 로고
    • Intraesophageal chemicals enhance responses of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats. Program No. 346.23/T18. In
    • Atlanta, GA: Society for Neuroscience
    • Qin C, Farber JP, Foreman RD. Intraesophageal chemicals enhance responses of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats. Program No. 346.23/T18. In: 2006 Neuroscience Meeting Planner (Online). Atlanta, GA: Society for Neuroscience. http://www.sfn.org/am2006.
    • (2006) Neuroscience Meeting Planner (Online)
    • Qin, C.1    Farber, J.P.2    Foreman, R.D.3
  • 39
    • 33846047024 scopus 로고    scopus 로고
    • Modulatory effects and afferent pathways of gastric electrical stimulation on rat thoracic spinal neurons receiving input from the stomach
    • Qin C, Chen JD, Zhang J, Foreman RD. Modulatory effects and afferent pathways of gastric electrical stimulation on rat thoracic spinal neurons receiving input from the stomach. Neurosci Res 57: 29-39, 2007.
    • (2007) Neurosci Res , vol.57 , pp. 29-39
    • Qin, C.1    Chen, J.D.2    Zhang, J.3    Foreman, R.D.4
  • 40
    • 0034821550 scopus 로고    scopus 로고
    • Functional chest pain of esophageal origin: Hyperalgesia or motor dysfunction
    • Rao SS, Hayek B, Summers RW. Functional chest pain of esophageal origin: hyperalgesia or motor dysfunction. Am J Gastroenterol 96: 2584-2589, 2001.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2584-2589
    • Rao, S.S.1    Hayek, B.2    Summers, R.W.3
  • 41
    • 0025240912 scopus 로고
    • Effect of bradykinin on opossum esophageal longitudinal smooth muscle: Evidence for novel bradykinin receptors
    • Saha JK, Sengupta JN, Goyal RK. Effect of bradykinin on opossum esophageal longitudinal smooth muscle: evidence for novel bradykinin receptors. J Pharmacol Exp Ther 252: 1012-1020, 1990.
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 1012-1020
    • Saha, J.K.1    Sengupta, J.N.2    Goyal, R.K.3
  • 42
    • 0025720138 scopus 로고
    • Effects of bradykinin and bradykinin analogs on the opossum lower esophageal sphincter: Characterization of an inhibitory bradykinin receptor
    • Saha JK, Sengupta JN, Goyal RK. Effects of bradykinin and bradykinin analogs on the opossum lower esophageal sphincter: characterization of an inhibitory bradykinin receptor. J Pharmacol Exp Ther 259: 265-2673, 1991.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 265-2673
    • Saha, J.K.1    Sengupta, J.N.2    Goyal, R.K.3
  • 46
    • 7044253553 scopus 로고    scopus 로고
    • Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression
    • Sarkar S, Thompson DG, Woolf CJ, Hobson AR, Millane T, Aziz Q. Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression. Am J Gastroenterol 99: 1998-2006, 2004.
    • (2004) Am J Gastroenterol , vol.99 , pp. 1998-2006
    • Sarkar, S.1    Thompson, D.G.2    Woolf, C.J.3    Hobson, A.R.4    Millane, T.5    Aziz, Q.6
  • 47
    • 0032961162 scopus 로고    scopus 로고
    • Vagal esophageal receptors in anesthetized dogs: Mechanical and chemical responsiveness
    • Sekizawa S, Ishikawa T, Sant'Ambrogio FB, Sant'Ambrogio G. Vagal esophageal receptors in anesthetized dogs: mechanical and chemical responsiveness. J Appl Physiol 86: 1231-1235, 1999.
    • (1999) J Appl Physiol , vol.86 , pp. 1231-1235
    • Sekizawa, S.1    Ishikawa, T.2    Sant'Ambrogio, F.B.3    Sant'Ambrogio, G.4
  • 48
    • 0026483059 scopus 로고
    • Differential sensitivity to bradykinin of esophageal distension-sensitive mechanoreceptors in vagal and sympathetic afferents of the opossum
    • Sengupta JN, Saha JK, Goyal RK. Differential sensitivity to bradykinin of esophageal distension-sensitive mechanoreceptors in vagal and sympathetic afferents of the opossum. J Neurophysiol 68: 1053-1067, 1992.
    • (1992) J Neurophysiol , vol.68 , pp. 1053-1067
    • Sengupta, J.N.1    Saha, J.K.2    Goyal, R.K.3
  • 49
    • 0034611223 scopus 로고    scopus 로고
    • Sengupta JN. An overview of esophageal sensory receptors. Am J Med 108, Suppl 4a: 87S-89S, 2000.
    • Sengupta JN. An overview of esophageal sensory receptors. Am J Med 108, Suppl 4a: 87S-89S, 2000.
  • 50
    • 77952702906 scopus 로고    scopus 로고
    • Esophageal sensory physiology
    • Sengupta JN. Esophageal sensory physiology. GI Motility (Online). Nature Publishing Group. http://www. nature. com/gimo/contents/pt1/ full/gimo16. html.
    • GI Motility (Online)
    • Sengupta, J.N.1
  • 52
    • 0036310523 scopus 로고    scopus 로고
    • Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1
    • Sugiura T, Tominaga M, Katsuya H, Mizumura K. Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J Neurophysiol 88: 544-548, 2002.
    • (2002) J Neurophysiol , vol.88 , pp. 544-548
    • Sugiura, T.1    Tominaga, M.2    Katsuya, H.3    Mizumura, K.4
  • 53
    • 0041691167 scopus 로고    scopus 로고
    • Distribution of the vanilloid receptor (VR1) in the gastrointestinal tract
    • Ward SM, Bayguinov J, Won KJ, Grundy D, Berthoud HR. Distribution of the vanilloid receptor (VR1) in the gastrointestinal tract. J Comp Neurol 465: 121-135, 2003.
    • (2003) J Comp Neurol , vol.465 , pp. 121-135
    • Ward, S.M.1    Bayguinov, J.2    Won, K.J.3    Grundy, D.4    Berthoud, H.R.5
  • 54
    • 0141465060 scopus 로고    scopus 로고
    • Reflux, Barrett's oesophagus and adenocarcinoma: Burning questions
    • Wild CP, Hardie LJ. Reflux, Barrett's oesophagus and adenocarcinoma: burning questions. Nat Rev Cancer 3: 676-684, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 676-684
    • Wild, C.P.1    Hardie, L.J.2
  • 55
    • 1542317629 scopus 로고    scopus 로고
    • The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor
    • Willert RP, Woolf CJ, Hobson AR, Delaney C, Thompson DG, Aziz Q. The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor. Gastroenterology 126: 683-692, 2004.
    • (2004) Gastroenterology , vol.126 , pp. 683-692
    • Willert, R.P.1    Woolf, C.J.2    Hobson, A.R.3    Delaney, C.4    Thompson, D.G.5    Aziz, Q.6
  • 56
    • 15844373022 scopus 로고    scopus 로고
    • Vagal afferent nerves with nociceptive properties in guinea-pig oesophagus
    • Yu S, Undem BJ, Kollarik M. Vagal afferent nerves with nociceptive properties in guinea-pig oesophagus. J Physiol 563: 831-842, 2005.
    • (2005) J Physiol , vol.563 , pp. 831-842
    • Yu, S.1    Undem, B.J.2    Kollarik, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.