Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Peng, Zhongsheng ^a   Heath, Jonathon ^a   Drachenberg, Cinthia ^a   Raufman, Jean Pierre ^a   Xie, Guofeng ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Bethanechol; Cell proliferation; Cholinergic agonist; Colon cancer; Matrix metalloproteinase

Indexed keywords

AZOXYMETHANE; BETHANECHOL; COLLAGENASE 3; CYCLIN D1; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MATRILYSIN; MUSCARINIC M3 RECEPTOR; MUSCARINIC RECEPTOR; STROMELYSIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CHRM3 GENE; COLON ADENOCARCINOMA; COLON ADENOMA; COLON MUCOSA; COLON TUMOR; CONTROLLED STUDY; COX2 GENE; CYCLIN D1 GENE; EPIDERMAL GROWTH FACTOR RECEPTOR GENE; GENE EXPRESSION; HIF1ALPHA GENE; INTESTINE EPITHELIUM CELL; MALE; MATRIX METALLOPROTEINASE 10 GENE; MATRIX METALLOPROTEINASE 13 GENE; MATRIX METALLOPROTEINASE 7 GENE; MOUSE; NONHUMAN; ONCOGENE MYC; TUMOR VOLUME; UPREGULATION;

ADENOCARCINOMA; ANIMALS; AZOXYMETHANE; BETHANECHOL; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; CYCLIN D1; CYCLOOXYGENASE 2; GENE EXPRESSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTESTINAL MUCOSA; MALE; MATRIX METALLOPROTEINASE 10; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 7; MICE; MUSCARINIC AGONISTS; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, MUSCARINIC M3; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR BURDEN;

EID: 84876668366     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-204     Document Type: Article

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