-
1
-
-
84862625338
-
The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [ist-3]): A randomised controlled trial
-
IST-3 Collaborative Group
-
IST-3 Collaborative Group. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the Third International Stroke Trial [IST-3]): a randomised controlled trial. Lancet. 2012; 379:2352-2363.
-
(2012)
Lancet
, vol.379
, pp. 2352-2363
-
-
-
2
-
-
84862588817
-
Rt-pa for ischaemic stroke: What will the next question be?
-
Leys D, Cordonnier C. rt-PA for ischaemic stroke: what will the next question be? Lancet. 2012;379:2320-2321.
-
(2012)
Lancet
, vol.379
, pp. 2320-2321
-
-
Leys, D.1
Cordonnier, C.2
-
3
-
-
84862629039
-
Recombinant tissue plasminogen activator for acute ischaemic stroke: An updated systematic review and meta-analysis
-
Wardlaw JM, Murray V, Berge E, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet. 2012;379:2364-2372.
-
(2012)
Lancet
, vol.379
, pp. 2364-2372
-
-
Wardlaw, J.M.1
Murray, V.2
Berge, E.3
-
4
-
-
34047133178
-
Articulating and responding to uncertainties in clinical research
-
DOI 10.1080/03605310701255719, PII 777158887
-
Djulbegovic B. Articulating and responding to uncertainties in clinical research. J Med Philos. 2012;32:79-98. doi:10.1080/03605310701255719. (Pubitemid 46598161)
-
(2007)
Journal of Medicine and Philosophy
, vol.32
, Issue.2
, pp. 79-98
-
-
Djulbegovic, B.1
-
5
-
-
82255173763
-
Update on the third international stroke trial (ist-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
-
doi:10.1186/1745-6215-12-252
-
Sandercock PP, Lindley RR, Wardlaw JJ, et al. Update on the Third International Stroke Trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited. Trials. 2011;12:252-252. doi:10.1186/1745-6215-12-252.
-
(2011)
Trials
, vol.12
, pp. 252-252
-
-
Sandercock, P.P.1
Lindley, R.R.2
Wardlaw, J.J.3
-
6
-
-
0030886956
-
The nocebo effect: History and physiology
-
Benson H. The nocebo effect: history and physiology. Prev Med. 1997;26(5 pt 1):612-615.
-
(1997)
Prev Med
, vol.26
, Issue.5 PART 1
, pp. 612-615
-
-
Benson, H.1
-
7
-
-
0030930843
-
Nocebo: The power of suggestibility
-
Spiegel H. Nocebo: the power of suggestibility. Prev Med. 1997; 26(5 pt 1):616-621.
-
(1997)
Prev Med
, vol.26
, Issue.5 PART 1
, pp. 616-621
-
-
Spiegel, H.1
-
9
-
-
21444446932
-
The placebo is powerful: Estimating placebo effects in medicine and psychotherapy from randomized clinical trials
-
DOI 10.1002/jclp.20129
-
Wampold BE, Minami T, Tierney SC, et al. The placebo is powerful: estimating placebo effects in medicine and psychotherapy from randomized clinical trials. J Clin Psychol. 2005;61:835-854. (Pubitemid 41153534)
-
(2005)
Journal of Clinical Psychology
, vol.61
, Issue.7
, pp. 835-854
-
-
Wampold, B.E.1
Minami, T.2
Tierney, S.C.3
Baskin, T.W.4
Bhati, K.S.5
-
10
-
-
84867320623
-
How is more negative evidence being used to support claims of benefit: The curious case of the third international stroke trial (ist-3)
-
Hoffman J, Cooper R. How is more negative evidence being used to support claims of benefit: the curious case of the Third International Stroke Trial (IST-3). Emerg Med Australas. 2012;24: 473-476.
-
(2012)
Emerg Med Australas
, vol.24
, pp. 473-476
-
-
Hoffman, J.1
Cooper, R.2
-
11
-
-
33947603295
-
Design of randomized controlled trials
-
DOI 10.1161/CIRCULATIONAHA.105.594945, PII 0000301720070306000014
-
Stanley K. Design of randomized controlled trials. Circulation. 2007;115:1164-1169. (Pubitemid 46673177)
-
(2007)
Circulation
, vol.115
, Issue.9
, pp. 1164-1169
-
-
Stanley, K.1
-
12
-
-
0037153701
-
Data dredging, bias, or confounding
-
Smith GD, Ebrahim S. Data dredging, bias, or confounding. BMJ. 2002;325:1437-1438. (Pubitemid 36026785)
-
(2002)
British Medical Journal
, vol.325
, Issue.7378
, pp. 1437-1438
-
-
Davey Smith, G.1
Ebrahim, S.2
-
13
-
-
0028783948
-
Tissue plasminogen activator for acute ischemic stroke
-
National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group
-
National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
-
(1995)
N Engl J Med
, vol.333
, pp. 1581-1587
-
-
-
15
-
-
0343118114
-
Intracerebral hemorrhage after intravenous t-pa therapy for ischemic stroke
-
National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group
-
National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke. 1997;28:2109-2118.
-
(1997)
Stroke
, vol.28
, pp. 2109-2118
-
-
-
17
-
-
79961209392
-
Optimal end points for acute stroke therapy trials: Best ways to measure treatment effects of drugs and devices
-
Saver JL. Optimal end points for acute stroke therapy trials: best ways to measure treatment effects of drugs and devices. Stroke. 2011;42:2356-2362.
-
(2011)
Stroke
, vol.42
, pp. 2356-2362
-
-
Saver, J.L.1
-
18
-
-
33646486740
-
The cost of dichotomising continuous variables
-
Altman DG, Royston P. The cost of dichotomising continuous variables. BMJ. 2006;332:1080. (Pubitemid 44365491)
-
(2006)
British Medical Journal
, vol.332
, Issue.7549
, pp. 1080
-
-
Altman, D.G.1
Royston, P.2
-
19
-
-
84937711503
-
A critical review of stroke trial analytical methodology: Outcome measures, study design, and correction for imbalances
-
In: Lapchack PA, Zhang JH, eds New York, NY: Springer
-
Mandava P, Yogesh P, Krumpelman C, et al. A critical review of stroke trial analytical methodology: outcome measures, study design, and correction for imbalances. In: Lapchack PA, Zhang JH, eds. Translational Stroke Research: From Target Selection to Clinical Trials. New York, NY: Springer; 2012:833-862.
-
(2012)
Translational Stroke Research: From Target Selection to Clinical Trials
, pp. 833-862
-
-
Mandava, P.1
Yogesh, P.2
Krumpelman, C.3
-
20
-
-
70349686724
-
Reliability of the modified rankin scale: Systematic review
-
Quinn TJ, Dawson J, Walters MR, et al. Reliability of the modified Rankin Scale: systematic review. Stroke. 2009;40:3393-3395.
-
(2009)
Stroke
, vol.40
, pp. 3393-3395
-
-
Quinn, T.J.1
Dawson, J.2
Walters, M.R.3
-
21
-
-
84858118130
-
Predicting outcome of iv thrombolysis-treated ischemic stroke patients
-
Strbian D, Meretoja A, Ahlhelm FJ, et al. Predicting outcome of IV thrombolysis-treated ischemic stroke patients. Neurology. 2012; 78:427-432.
-
(2012)
Neurology
, vol.78
, pp. 427-432
-
-
Strbian, D.1
Meretoja, A.2
Ahlhelm, F.J.3
-
22
-
-
84860223906
-
The iscore predicts effectiveness of thrombolytic therapy for acute ischemic stroke
-
Saposnik G, Fang J, Kapral M, et al. The iScore predicts effectiveness of thrombolytic therapy for acute ischemic stroke. Stroke. 2012;43:1315-1322.
-
(2012)
Stroke
, vol.43
, pp. 1315-1322
-
-
Saposnik, G.1
Fang, J.2
Kapral, M.3
-
23
-
-
52649165720
-
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
-
Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008; 359:1317-1329.
-
(2008)
N Engl J Med
, vol.359
, pp. 1317-1329
-
-
Hacke, W.1
Kaste, M.2
Bluhmki, E.3
-
24
-
-
35648965675
-
Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials
-
DOI 10.1161/STROKEAHA.107.488536, PII 0000767020071100000031
-
Saver JL. Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials. Stroke. 2007;38:3055-3062. (Pubitemid 350035704)
-
(2007)
Stroke
, vol.38
, Issue.11
, pp. 3055-3062
-
-
Saver, J.L.1
-
25
-
-
0037079398
-
Does declaration of competing interests affect readers' perceptions? A randomised trial
-
Chaudhry S, Schroter S, Smith R, et al. Does declaration of competing interests affect readers' perceptions? a randomized trial. BMJ. 2002;325:1391-1392. (Pubitemid 35477844)
-
(2002)
British Medical Journal
, vol.325
, Issue.7377
, pp. 1391-1392
-
-
Chaudhry, S.1
Schroter, S.2
Smith, R.3
Morris, J.4
-
26
-
-
77955898841
-
Failure to discount for conflict of interest when evaluating medical literature: A randomized trial of physicians
-
Silverman GK, Loewenstein GF, Anderson BL, et al. Failure to discount for conflict of interest when evaluating medical literature: a randomized trial of physicians. J Med Ethics. 2010; 36:265-270.
-
(2010)
J Med Ethics
, vol.36
, pp. 265-270
-
-
Silverman, G.K.1
Loewenstein, G.F.2
Anderson, B.L.3
-
27
-
-
84866345932
-
A randomized study of how physicians interpret research funding disclosures
-
Kesselheim AS, Robertson CT, Myers JA, et al. A randomized study of how physicians interpret research funding disclosures. N Engl J Med. 2012;367:1119-1127.
-
(2012)
N Engl J Med
, vol.367
, pp. 1119-1127
-
-
Kesselheim, A.S.1
Robertson, C.T.2
Myers, J.A.3
-
28
-
-
84866353890
-
Believe the data
-
Drazen JM. Believe the data. N Engl J Med. 2012;367:1152-1153.
-
(2012)
N Engl J Med
, vol.367
, pp. 1152-1153
-
-
Drazen, J.M.1
-
29
-
-
0037460196
-
Scope and impact of financial conflicts of interest in biomedical research: A systematic review
-
Bekelman JE, Li Y, Gross CP. Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA. 2003;289:454-469.
-
(2003)
JAMA
, vol.289
, pp. 454-469
-
-
Bekelman, J.E.1
Li, Y.2
Gross, C.P.3
-
30
-
-
0038439242
-
Pharmaceutical industry sponsorship and research outcome and quality: Systematic review
-
Lexchin J, Bero LA, Djulbegovic B, et al. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ. 2003;326:1167-1170. (Pubitemid 36649048)
-
(2003)
British Medical Journal
, vol.326
, Issue.7400
, pp. 1167-1170
-
-
Lexchin, J.1
Bero, L.A.2
Djulbegovic, B.3
Clark, O.4
-
31
-
-
41449086626
-
How pharmaceutical industry funding affects trial outcomes: Causal structures and responses
-
DOI 10.1016/j.socscimed.2008.01.010, PII S0277953608000361
-
Sismondo S. How pharmaceutical industry funding affects trial outcomes: causal structures and responses. Soc Sci Med. 2008; 66:1909-1914. (Pubitemid 351454041)
-
(2008)
Social Science and Medicine
, vol.66
, Issue.9
, pp. 1909-1914
-
-
Sismondo, S.1
-
32
-
-
20444472391
-
Medical specialists and pharmaceutical industry-sponsored research: A survey of the Australian experience
-
Henry DA, Kerridge IH, Hill SR, et al. Medical specialists and pharmaceutical industry-sponsored research: a survey of the Australian experience. Med J Aust. 2005;182:557-560. (Pubitemid 40823472)
-
(2005)
Medical Journal of Australia
, vol.182
, Issue.11
, pp. 557-560
-
-
Henry, D.A.1
Kerridge, I.H.2
Hill, S.R.3
McNeill, P.M.4
Doran, E.5
Newby, D.A.6
Henderson, K.M.7
Maguire, J.8
Stokes, B.J.9
Macdonald, G.J.10
Day, R.O.11
-
33
-
-
0038777090
-
Evidence b(i)ased medicine - Selective reporting from studies sponsored by pharmaceutical industry: Review of studies in new drug applications
-
Melander H, Ahlqvist-Rastad J, Meijer G, et al. Evidence b(i)ased medicine -selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ. 2003;326:1171-1173. (Pubitemid 36649049)
-
(2003)
British Medical Journal
, vol.326
, Issue.7400
, pp. 1171-1173
-
-
Melander, H.1
Ahlqvist-Rastad, J.2
Meijer, G.3
Beermann, B.4
-
34
-
-
84863593744
-
High reprint orders in medical journals and pharmaceutical industry funding: A casecontrol study
-
doi:10.1136/bmj.e4212
-
Handel AE, Patel SV, Pakpoor J, et al. High reprint orders in medical journals and pharmaceutical industry funding: a casecontrol study. BMJ. 2012;344:e4212. doi:10.1136/bmj.e4212.
-
(2012)
BMJ
, vol.344
-
-
Handel, A.E.1
Patel, S.V.2
Pakpoor, J.3
-
35
-
-
0043198131
-
Association of Funding and Conclusions in Randomized Drug Trials: A Reflection of Treatment Effect or Adverse Events?
-
DOI 10.1001/jama.290.7.921
-
Als-Nielsen B. Association of funding and conclusions in randomized drug trials: a reflection of treatment effect or adverse events? JAMA. 2003;290:921-928. (Pubitemid 37430464)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.7
, pp. 921-928
-
-
Als-Nielsen, B.1
Chen, W.2
Gluud, C.3
Kjaergard, L.L.4
-
36
-
-
84866639664
-
Misrepresentation of randomized controlled trials in press releases and news coverage: A cohort study
-
Yavchitz A, Boutron I, Bafeta A, et al. Misrepresentation of randomized controlled trials in press releases and news coverage: a cohort study. PLoS Med. 2012;9:e1001308.
-
(2012)
PLoS Med
, vol.9
-
-
Yavchitz, A.1
Boutron, I.2
Bafeta, A.3
-
37
-
-
46249100474
-
Predicting long-term outcome after acute ischemic stroke: A simple index works in patients from controlled clinical trials
-
König R, Ziegler A, BluhmkiE, et al. Predicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trials. Stroke. 2008;39:1821-1826.
-
(2008)
Stroke
, vol.39
, pp. 1821-1826
-
-
König, R.1
Ziegler, A.2
Bluhmki, E.3
|