메뉴 건너뛰기




Volumn 61, Issue 4, 2013, Pages 489-498

Rt-PA and stroke: Does IST-3 make it all clear or muddy the waters?

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE;

EID: 84876570671     PISSN: 01960644     EISSN: 10976760     Source Type: Journal    
DOI: 10.1016/j.annemergmed.2012.12.008     Document Type: Article
Times cited : (5)

References (37)
  • 1
    • 84862625338 scopus 로고    scopus 로고
    • The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [ist-3]): A randomised controlled trial
    • IST-3 Collaborative Group
    • IST-3 Collaborative Group. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the Third International Stroke Trial [IST-3]): a randomised controlled trial. Lancet. 2012; 379:2352-2363.
    • (2012) Lancet , vol.379 , pp. 2352-2363
  • 2
    • 84862588817 scopus 로고    scopus 로고
    • Rt-pa for ischaemic stroke: What will the next question be?
    • Leys D, Cordonnier C. rt-PA for ischaemic stroke: what will the next question be? Lancet. 2012;379:2320-2321.
    • (2012) Lancet , vol.379 , pp. 2320-2321
    • Leys, D.1    Cordonnier, C.2
  • 3
    • 84862629039 scopus 로고    scopus 로고
    • Recombinant tissue plasminogen activator for acute ischaemic stroke: An updated systematic review and meta-analysis
    • Wardlaw JM, Murray V, Berge E, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet. 2012;379:2364-2372.
    • (2012) Lancet , vol.379 , pp. 2364-2372
    • Wardlaw, J.M.1    Murray, V.2    Berge, E.3
  • 4
    • 34047133178 scopus 로고    scopus 로고
    • Articulating and responding to uncertainties in clinical research
    • DOI 10.1080/03605310701255719, PII 777158887
    • Djulbegovic B. Articulating and responding to uncertainties in clinical research. J Med Philos. 2012;32:79-98. doi:10.1080/03605310701255719. (Pubitemid 46598161)
    • (2007) Journal of Medicine and Philosophy , vol.32 , Issue.2 , pp. 79-98
    • Djulbegovic, B.1
  • 5
    • 82255173763 scopus 로고    scopus 로고
    • Update on the third international stroke trial (ist-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
    • doi:10.1186/1745-6215-12-252
    • Sandercock PP, Lindley RR, Wardlaw JJ, et al. Update on the Third International Stroke Trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited. Trials. 2011;12:252-252. doi:10.1186/1745-6215-12-252.
    • (2011) Trials , vol.12 , pp. 252-252
    • Sandercock, P.P.1    Lindley, R.R.2    Wardlaw, J.J.3
  • 6
    • 0030886956 scopus 로고    scopus 로고
    • The nocebo effect: History and physiology
    • Benson H. The nocebo effect: history and physiology. Prev Med. 1997;26(5 pt 1):612-615.
    • (1997) Prev Med , vol.26 , Issue.5 PART 1 , pp. 612-615
    • Benson, H.1
  • 7
    • 0030930843 scopus 로고    scopus 로고
    • Nocebo: The power of suggestibility
    • Spiegel H. Nocebo: the power of suggestibility. Prev Med. 1997; 26(5 pt 1):616-621.
    • (1997) Prev Med , vol.26 , Issue.5 PART 1 , pp. 616-621
    • Spiegel, H.1
  • 9
    • 21444446932 scopus 로고    scopus 로고
    • The placebo is powerful: Estimating placebo effects in medicine and psychotherapy from randomized clinical trials
    • DOI 10.1002/jclp.20129
    • Wampold BE, Minami T, Tierney SC, et al. The placebo is powerful: estimating placebo effects in medicine and psychotherapy from randomized clinical trials. J Clin Psychol. 2005;61:835-854. (Pubitemid 41153534)
    • (2005) Journal of Clinical Psychology , vol.61 , Issue.7 , pp. 835-854
    • Wampold, B.E.1    Minami, T.2    Tierney, S.C.3    Baskin, T.W.4    Bhati, K.S.5
  • 10
    • 84867320623 scopus 로고    scopus 로고
    • How is more negative evidence being used to support claims of benefit: The curious case of the third international stroke trial (ist-3)
    • Hoffman J, Cooper R. How is more negative evidence being used to support claims of benefit: the curious case of the Third International Stroke Trial (IST-3). Emerg Med Australas. 2012;24: 473-476.
    • (2012) Emerg Med Australas , vol.24 , pp. 473-476
    • Hoffman, J.1    Cooper, R.2
  • 11
    • 33947603295 scopus 로고    scopus 로고
    • Design of randomized controlled trials
    • DOI 10.1161/CIRCULATIONAHA.105.594945, PII 0000301720070306000014
    • Stanley K. Design of randomized controlled trials. Circulation. 2007;115:1164-1169. (Pubitemid 46673177)
    • (2007) Circulation , vol.115 , Issue.9 , pp. 1164-1169
    • Stanley, K.1
  • 12
  • 13
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group
    • National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 15
    • 0343118114 scopus 로고    scopus 로고
    • Intracerebral hemorrhage after intravenous t-pa therapy for ischemic stroke
    • National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group
    • National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke. 1997;28:2109-2118.
    • (1997) Stroke , vol.28 , pp. 2109-2118
  • 17
    • 79961209392 scopus 로고    scopus 로고
    • Optimal end points for acute stroke therapy trials: Best ways to measure treatment effects of drugs and devices
    • Saver JL. Optimal end points for acute stroke therapy trials: best ways to measure treatment effects of drugs and devices. Stroke. 2011;42:2356-2362.
    • (2011) Stroke , vol.42 , pp. 2356-2362
    • Saver, J.L.1
  • 18
    • 33646486740 scopus 로고    scopus 로고
    • The cost of dichotomising continuous variables
    • Altman DG, Royston P. The cost of dichotomising continuous variables. BMJ. 2006;332:1080. (Pubitemid 44365491)
    • (2006) British Medical Journal , vol.332 , Issue.7549 , pp. 1080
    • Altman, D.G.1    Royston, P.2
  • 19
    • 84937711503 scopus 로고    scopus 로고
    • A critical review of stroke trial analytical methodology: Outcome measures, study design, and correction for imbalances
    • In: Lapchack PA, Zhang JH, eds New York, NY: Springer
    • Mandava P, Yogesh P, Krumpelman C, et al. A critical review of stroke trial analytical methodology: outcome measures, study design, and correction for imbalances. In: Lapchack PA, Zhang JH, eds. Translational Stroke Research: From Target Selection to Clinical Trials. New York, NY: Springer; 2012:833-862.
    • (2012) Translational Stroke Research: From Target Selection to Clinical Trials , pp. 833-862
    • Mandava, P.1    Yogesh, P.2    Krumpelman, C.3
  • 20
    • 70349686724 scopus 로고    scopus 로고
    • Reliability of the modified rankin scale: Systematic review
    • Quinn TJ, Dawson J, Walters MR, et al. Reliability of the modified Rankin Scale: systematic review. Stroke. 2009;40:3393-3395.
    • (2009) Stroke , vol.40 , pp. 3393-3395
    • Quinn, T.J.1    Dawson, J.2    Walters, M.R.3
  • 21
    • 84858118130 scopus 로고    scopus 로고
    • Predicting outcome of iv thrombolysis-treated ischemic stroke patients
    • Strbian D, Meretoja A, Ahlhelm FJ, et al. Predicting outcome of IV thrombolysis-treated ischemic stroke patients. Neurology. 2012; 78:427-432.
    • (2012) Neurology , vol.78 , pp. 427-432
    • Strbian, D.1    Meretoja, A.2    Ahlhelm, F.J.3
  • 22
    • 84860223906 scopus 로고    scopus 로고
    • The iscore predicts effectiveness of thrombolytic therapy for acute ischemic stroke
    • Saposnik G, Fang J, Kapral M, et al. The iScore predicts effectiveness of thrombolytic therapy for acute ischemic stroke. Stroke. 2012;43:1315-1322.
    • (2012) Stroke , vol.43 , pp. 1315-1322
    • Saposnik, G.1    Fang, J.2    Kapral, M.3
  • 23
    • 52649165720 scopus 로고    scopus 로고
    • Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
    • Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008; 359:1317-1329.
    • (2008) N Engl J Med , vol.359 , pp. 1317-1329
    • Hacke, W.1    Kaste, M.2    Bluhmki, E.3
  • 24
    • 35648965675 scopus 로고    scopus 로고
    • Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials
    • DOI 10.1161/STROKEAHA.107.488536, PII 0000767020071100000031
    • Saver JL. Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials. Stroke. 2007;38:3055-3062. (Pubitemid 350035704)
    • (2007) Stroke , vol.38 , Issue.11 , pp. 3055-3062
    • Saver, J.L.1
  • 25
    • 0037079398 scopus 로고    scopus 로고
    • Does declaration of competing interests affect readers' perceptions? A randomised trial
    • Chaudhry S, Schroter S, Smith R, et al. Does declaration of competing interests affect readers' perceptions? a randomized trial. BMJ. 2002;325:1391-1392. (Pubitemid 35477844)
    • (2002) British Medical Journal , vol.325 , Issue.7377 , pp. 1391-1392
    • Chaudhry, S.1    Schroter, S.2    Smith, R.3    Morris, J.4
  • 26
    • 77955898841 scopus 로고    scopus 로고
    • Failure to discount for conflict of interest when evaluating medical literature: A randomized trial of physicians
    • Silverman GK, Loewenstein GF, Anderson BL, et al. Failure to discount for conflict of interest when evaluating medical literature: a randomized trial of physicians. J Med Ethics. 2010; 36:265-270.
    • (2010) J Med Ethics , vol.36 , pp. 265-270
    • Silverman, G.K.1    Loewenstein, G.F.2    Anderson, B.L.3
  • 27
    • 84866345932 scopus 로고    scopus 로고
    • A randomized study of how physicians interpret research funding disclosures
    • Kesselheim AS, Robertson CT, Myers JA, et al. A randomized study of how physicians interpret research funding disclosures. N Engl J Med. 2012;367:1119-1127.
    • (2012) N Engl J Med , vol.367 , pp. 1119-1127
    • Kesselheim, A.S.1    Robertson, C.T.2    Myers, J.A.3
  • 28
    • 84866353890 scopus 로고    scopus 로고
    • Believe the data
    • Drazen JM. Believe the data. N Engl J Med. 2012;367:1152-1153.
    • (2012) N Engl J Med , vol.367 , pp. 1152-1153
    • Drazen, J.M.1
  • 29
    • 0037460196 scopus 로고    scopus 로고
    • Scope and impact of financial conflicts of interest in biomedical research: A systematic review
    • Bekelman JE, Li Y, Gross CP. Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA. 2003;289:454-469.
    • (2003) JAMA , vol.289 , pp. 454-469
    • Bekelman, J.E.1    Li, Y.2    Gross, C.P.3
  • 30
    • 0038439242 scopus 로고    scopus 로고
    • Pharmaceutical industry sponsorship and research outcome and quality: Systematic review
    • Lexchin J, Bero LA, Djulbegovic B, et al. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ. 2003;326:1167-1170. (Pubitemid 36649048)
    • (2003) British Medical Journal , vol.326 , Issue.7400 , pp. 1167-1170
    • Lexchin, J.1    Bero, L.A.2    Djulbegovic, B.3    Clark, O.4
  • 31
    • 41449086626 scopus 로고    scopus 로고
    • How pharmaceutical industry funding affects trial outcomes: Causal structures and responses
    • DOI 10.1016/j.socscimed.2008.01.010, PII S0277953608000361
    • Sismondo S. How pharmaceutical industry funding affects trial outcomes: causal structures and responses. Soc Sci Med. 2008; 66:1909-1914. (Pubitemid 351454041)
    • (2008) Social Science and Medicine , vol.66 , Issue.9 , pp. 1909-1914
    • Sismondo, S.1
  • 33
    • 0038777090 scopus 로고    scopus 로고
    • Evidence b(i)ased medicine - Selective reporting from studies sponsored by pharmaceutical industry: Review of studies in new drug applications
    • Melander H, Ahlqvist-Rastad J, Meijer G, et al. Evidence b(i)ased medicine -selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ. 2003;326:1171-1173. (Pubitemid 36649049)
    • (2003) British Medical Journal , vol.326 , Issue.7400 , pp. 1171-1173
    • Melander, H.1    Ahlqvist-Rastad, J.2    Meijer, G.3    Beermann, B.4
  • 34
    • 84863593744 scopus 로고    scopus 로고
    • High reprint orders in medical journals and pharmaceutical industry funding: A casecontrol study
    • doi:10.1136/bmj.e4212
    • Handel AE, Patel SV, Pakpoor J, et al. High reprint orders in medical journals and pharmaceutical industry funding: a casecontrol study. BMJ. 2012;344:e4212. doi:10.1136/bmj.e4212.
    • (2012) BMJ , vol.344
    • Handel, A.E.1    Patel, S.V.2    Pakpoor, J.3
  • 35
    • 0043198131 scopus 로고    scopus 로고
    • Association of Funding and Conclusions in Randomized Drug Trials: A Reflection of Treatment Effect or Adverse Events?
    • DOI 10.1001/jama.290.7.921
    • Als-Nielsen B. Association of funding and conclusions in randomized drug trials: a reflection of treatment effect or adverse events? JAMA. 2003;290:921-928. (Pubitemid 37430464)
    • (2003) Journal of the American Medical Association , vol.290 , Issue.7 , pp. 921-928
    • Als-Nielsen, B.1    Chen, W.2    Gluud, C.3    Kjaergard, L.L.4
  • 36
    • 84866639664 scopus 로고    scopus 로고
    • Misrepresentation of randomized controlled trials in press releases and news coverage: A cohort study
    • Yavchitz A, Boutron I, Bafeta A, et al. Misrepresentation of randomized controlled trials in press releases and news coverage: a cohort study. PLoS Med. 2012;9:e1001308.
    • (2012) PLoS Med , vol.9
    • Yavchitz, A.1    Boutron, I.2    Bafeta, A.3
  • 37
    • 46249100474 scopus 로고    scopus 로고
    • Predicting long-term outcome after acute ischemic stroke: A simple index works in patients from controlled clinical trials
    • König R, Ziegler A, BluhmkiE, et al. Predicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trials. Stroke. 2008;39:1821-1826.
    • (2008) Stroke , vol.39 , pp. 1821-1826
    • König, R.1    Ziegler, A.2    Bluhmki, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.