Optimal end points for acute stroke therapy trials: Best ways to measure treatment effects of drugs and devices

Stroke

Volumn 42, Issue 8, 2011, Pages 2356-2362

  Saver, Jeffrey L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

acute cerebral hemorrhage; acute cerebral infarction; acute stroke syndromes; emergency treatment; neuroprotectors; thrombolysis

Indexed keywords

ACCURACY; ACUTE DISEASE; ADVERSE OUTCOME; BARTHEL INDEX; BRAIN HEMORRHAGE; CLINICAL ASSESSMENT TOOL; CLINICAL TRIAL (TOPIC); COMPUTER ASSISTED TOMOGRAPHY; DEVICE SAFETY; DISABILITY; DOPPLER ECHOGRAPHY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FUNCTIONAL DISEASE; FUNCTIONAL INDEPENDENCE MEASURE; GLASGOW OUTCOME SCALE; HEALTH CARE COST; HUMAN; MORTALITY; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANKIN SCALE; RATING SCALE; RELIABILITY; REPERFUSION; REVIEW; SALVAGE THERAPY; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; STROKE; THERAPY EFFECT; THROMBOLYSIS IN CEREBRAL INFARCTION AND ARTERIAL OCCLUSIVE LESION SCALE; VALIDITY; WORLD HEALTH ORGANIZATION;

BRAIN ISCHEMIA; CLINICAL TRIALS AS TOPIC; ENDPOINT DETERMINATION; HUMANS; STROKE; TREATMENT OUTCOME;

EID: 79961209392     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.619122     Document Type: Review

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