Dynamic migration and cell-cell interactions of early reprogramming revealed by high-resolution time-lapse imaging

Stem Cells

Volumn 31, Issue 5, 2013, Pages 895-905

  Megyola, Cynthia M ^a   Gao, Yuan ^a   Teixeira, Alexandra M ^a   Cheng, Jijun ^a   Heydari, Kartoosh ^a   Cheng, Ee Chun ^a   Nottoli, Timothy ^a   Krause, Diane S ^a   Lu, Jun ^a   Guo, Shangqin ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UVOMORULIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL INTERACTION; CELL MIGRATION; CELL STRUCTURE; COLONY FORMATION; COMPUTER PROGRAM; CONTROLLED STUDY; FEMALE; GRANULOCYTE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IMAGE ANALYSIS; IMAGE PROCESSING; MALE; MICROSCOPY; MONOCYTE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; SATELLITE CELL; SINGLE CELL ANALYSIS; TIME LAPSE IMAGING;

ANIMALS; CADHERINS; CELL COMMUNICATION; CELL MOVEMENT; CELLS, CULTURED; EMBRYONIC STEM CELLS; FEMALE; MICE; MICE, INBRED C57BL; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELLS; TIME-LAPSE IMAGING;

EID: 84876537499     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1323     Document Type: Article

References (31)

1. Wernig M, Meissner A, Foreman R et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007;448:318-324. (Pubitemid 47080337)
2. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676. (Pubitemid 44233629)
3. Park IH, Zhao R, West JA et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008;451:141-146.
4. Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872. (Pubitemid 350138099)
5. Hochedlinger K, Plath K. Epigenetic reprogramming and induced pluripotency. Development 2009;136:509-523.
6. Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues. Cell 2010;143:508-525.
7. Eminli S, Foudi A, Stadtfeld M et al. Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nat Genet 2009;41:968-976.
8. Hanna J, Saha K, Pando B et al. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 2009;462:595-601.
9. Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 2008;132:567-582. (Pubitemid 351253686)
10. Araki R, Jincho Y, Hoki Y et al. Conversion of ancestral fibroblasts to induced pluripotent stem cells. Stem Cells 2010;28:213-220.
11. Chan EM, Ratanasirintrawoot S, Park IH et al. Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotechnol 2009;27:1033-1037.
12. Smith ZD, Nachman I, Regev A et al. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event. Nat Biotechnol 2010;28:521-526.
13. Warlich E, Kuehle J, Cantz T et al. Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol Ther 2011;19:782-789.
14. Akashi K, Traver D, Miyamoto T et al. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000;404:193-197. (Pubitemid 30154488)
15. Ying QL, Wray J, Nichols J et al. The ground state of embryonic stem cell self-renewal. Nature 2008;453:519-523. (Pubitemid 351733324)
16. Nichols J, Silva J, Roode M et al. Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development 2009;136:3215-3222.
17. Nagy A, Gertsenstein M, Vintersten K, et al. Manipulating the Mouse Embryo: A Laboratory Manual (Third Edition). 2003.
18. Guo S, Lu J, Schlanger R et al. MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci USA 2010;107:14229-14234.
19. Chou YF, Chen HH, Eijpe M et al. The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells. Cell 2008;135:449-461.
20. Marson A, Levine SS, Cole MF et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008;134:521-533.
21. Carey BW, Markoulaki S, Hanna J et al. Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc Natl Acad Sci USA 2009;106:157-162.
22. Chen T, Yuan D, Wei B et al. E-cadherin-mediated cell-cell contact is critical for induced pluripotent stem cell generation. Stem Cells 2010;28:1315-1325.
23. Li R, Liang J, Ni S et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 2010;7:51-63.
24. Redmer T, Diecke S, Grigoryan T et al. E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming. EMBO Rep 2011;12:720-726.
25. Samavarchi-Tehrani P, Golipour A, David L et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 2010;7:64-77.
26. Polo JM, Hochedlinger K. When fibroblasts MET iPSCs. Cell Stem Cell 2010;7:5-6.
27. Li D, Zhou J, Wang L et al. Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. J Cell Biol 2010;191:631-644.
28. Boussadia O, Kutsch S, Hierholzer A et al. E-cadherin is a survival factor for the lactating mouse mammary gland. Mech Dev 2002;115:53-62. (Pubitemid 34615667)
29. Perl AK, Wert SE, Nagy A et al. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci USA 2002;99:10482-10487.
30. Ohgushi M, Matsumura M, Eiraku M et al. Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells. Cell Stem Cell 2010;7:225-239.
31. Stadtfeld M, Hochedlinger K. Induced pluripotency: History, mechanisms, and applications. Genes Dev 2010;24:2239-2263.