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1
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0027943163
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Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor
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Fukudome K, Esmon CT. Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor. J Biol Chem 1994;269(42):26486-91.
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Endothelial cell protein C receptor acts as a cellular receptor for factor Vila on endothelium
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Ghosh S, Pendurthi UR, Steinoe A, Esmon CT, Rao Lu. Endothelial cell protein C receptor acts as a cellular receptor for factor Vila on endothelium. J Biol Chem 2007;282(16):11849-57.
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Inflammation and thrombosis
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Esmon CT. Inflammation and thrombosis. J Thromb Haemost 2003,1(7):1343-8.
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Expression and shedding of endothelial protein C receptor in prostate cancer cells
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Menschikowski M, Hagelgans A, Tiebel O, Klinsmann L, Eisenhofer G, Siegert G. Expression and shedding of endothelial protein C receptor in prostate cancer cells. Cancer Cell Int 2011;11:4.
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Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1
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Beaulieu LM, Church FC. Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1. Exp Cell Res 2006;313(4):677-87.
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Expression of the vascular endothelial cell protein C receptor in epithelial tumour cells
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Scheffer GL, Flens MJ, Hageman S, Izquierdo MA, Shoemaker RH, Scheper RJ. Expression of the vascular endothelial cell protein C receptor in epithelial tumour cells. Eur J Cancer 2002; 38(11):1535-42.
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Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways
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Menschikowski M, Hagelgans A, Eisenhofer G, Siegert G. Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways. Exp Cell Res 2009;315(15):2673-82.
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Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor
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Mosnier LO, Griffin JH. Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor. Biochem J 2003;373(1):65-70.
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Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia
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Zheng X, Li W, Song Y, et al. Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia. J Thromb Haemost 2007;5(7):1394-400.
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Shedding of endothelial protein C receptor contributes to vasculopathy and renal injury in lupus: In vivo and in vitro evidence
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Sesin CA, Yin X, Esmon CT, Buyon JP, Clancy RM. Shedding of endothelial protein C receptor contributes to vasculopathy and renal injury in lupus: In vivo and in vitro evidence. Kidney Int 2005;68(1):110-20.
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11
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36749017585
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Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes
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Xue M, March L, Sambrook PN, Fukudome K, Jackson CJ. Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes. Ann Rheum Dis 2007;66(12):1574-8
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Role of activated protein C and its receptor in inhibition of tumor metastasis
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Bezuhly M, Cullen R, Esmon CT, et al. Role of activated protein C and its receptor in inhibition of tumor metastasis. Blood 2009;113(14):3371-4.
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Blood
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Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement
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Van Sluis GL, Niers TM, Esmon CT, et al. Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement. Blood 2009;114(9):1968-73.
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