Physicians' opinions of stress ulcer prophylaxis: Survey results from a large urban medical center

Digestive Diseases and Sciences

Volumn 58, Issue 3, 2013, Pages 777-781

  Koczka, Charles P ^a   Geraldino Pardilla, Laura B ^b   Goodman, Adam J ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b Department of Orthopaedic Surgery   (United States)

Author keywords

Attitude; Inhibitor; Knowledge; Practice; Prophylaxis; Proton; Pump; Stress; Ulcer

Indexed keywords

PROTON PUMP INHIBITOR; STEROID; STOMACH SECRETION INHIBITOR;

ARTICLE; BURN PATIENT; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG INDICATION; HUMAN; INTUBATION; LIVER FAILURE; MEDICAL DECISION MAKING; MEDICAL PRACTICE; PHYSICIAN ATTITUDE; PRACTICE GUIDELINE; PRESCRIPTION; PRIORITY JOURNAL; PROPHYLAXIS; PUBLICATION; RESIDENT; RESPIRATORY DISTRESS; RISK FACTOR; STRESS ULCER; URBAN AREA;

ANTI-ULCER AGENTS; DATA COLLECTION; DECISION MAKING; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; INTERNSHIP AND RESIDENCY; PHYSICIANS; STRESS, PHYSIOLOGICAL; ULCER;

EID: 84876527141     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2423-x     Document Type: Article

References (31)

1. Naunton M, Peterson GM, Bleasel MD. Overuse of proton-pump inhibitors. J Clin Pharm Ther. 2000;25:333-340.
2. Leditschke IA, Coombes JA. Concordance between use of proton-pump inhibitors and prescribing guidelines. Med J Aust. 2000;172:564.
3. Parente F, Cucino C, Gallus S, et al. Hospital use of acid-suppressive medications and its fall-out on prescribing in general practice: a 1-month survey. Aliment Pharmacol Ther. 2003;17:1503-1506.
4. Walker NM, McDonald J. An evaluation of the use of proton-pump inhibitors. Pharm World Sci. 2001;23:116-117.
5. Sebastian SS, Kernan N, Qasim A, O'Morain CA, Buckley M. Appropriateness of gastric antisecretory therapy in hospital practice. Ir J Med Sci. 2003;172:115-117.
6. Grant K, Al-Adhami N, Tordoff J, Livesey J, Barbezat G, Reith D. Continuation of proton-pump inhibitors from hospital to community. Pharm World Sci. 2006;28:189-193.
7. Pham CQ, Regal RE, Bostwick TR, Knauf KS. Acid suppressive therapy use on an inpatient internal medicine service. Ann Pharmacother. 2006;40:1261-1266.
8. Kleiman RL, Adair CG, Ephgrave KS. Stress ulcers: current understanding of pathogenesis and prophylaxis. Drug Intell Clin Pharm. 1988;22:452-460.
9. Grube RR, May DB. Stress ulcer prophylaxis in hospitalized patients not in intensive care units. Am J Health Syst Pharm. 2007;64:1396-1400.
10. ASHP Therapeutic Guidelines on Stress Ulcer Prophylaxis. ASHP Commission on Therapeutics and approved by the ASHP Board of Directors on November 14, 1998. Am J Health Syst Pharm. 1999;56:347-379.
11. Murphy CE, Stevens AM, Ferrentino N, et al. Frequency of inappropriate continuation of acid suppressive therapy after discharge in patients who began therapy in the surgical intensive care unit. Pharmacotherapy. 2008;28:968-976.
12. Saccar CL. The pharmacology of esomeprazole and its role in gastric acid related diseases. Expert Opin Drug Metab Toxicol. 2009;5:1113-1124.
13. Radhofer-Welte S. Pharmacokinetics and metabolism of the proton-pump inhibitor pantoprazole in man. Drugs Today (Barc). 1999;35:765-772.
14. Nardino RJ, Vender RJ, Herbert PN. Overuse of acid-suppressive therapy in hospitalized patients. Am J Gastroenterol. 2000;95:3118-3122.
15. Smith DM, Cox MR, Brazening EJ, et al. An intervention on discharge polypharmacy. J Am Geriatr Soc. 1996;44:416-419.
16. Laheij RJ, Sturkenboom MC, Hassing RJ, Dieleman J, Stricker BH, Jansen JB. Risk of community-acquired pneumonia and use of gastric acid-suppressive drugs. JAMA. 2004;292:1955-1960.
17. Sarkar M, Hennessy S, Yang YX. Proton-pump inhibitor use and the risk for community acquired pneumonia. Ann Intern Med. 2008;149:391-398.
18. Rodríguez LA, Ruigómez A, Wallander MA, Johansson S. Acid-suppressive drugs and community-acquired pneumonia. Epidemiology. 2009;20:800-806.
19. Rath T, Walzer LR, Meissl G. Preventive measures for stress ulcers in burn patients. Burns Incl Therm Inj. 1988;14:504-507.
20. Xiao SC, Zhu SH, Xia ZF, et al. Prevention and treatment of gastrointestinal dysfunction following severe burns: a summary of recent 30-year clinical experience. World J Gastroenterol. 2008;14:3231-3235.
21. Ali T, Harty RF. Stress-induced ulcer bleeding in critically ill patients. Gastroenterol Clin North Am. 2009 Jun;38:245-265.
22. Popović N. Importance of prevention of acute mucosal lesions in patients in intensive care units. Acta Chir Iugosl. 2007;54:47-50.
23. Bickler SW, Harrison MW, Campbell JR. Perforated peptic ulcer disease in children: association of corticosteroid therapy. J Pediatr Surg. 1993;28:785-787.
24. Luo JC, Shin VY, Liu ES, et al. Non-ulcerogenic dose of dexamethasone delays gastric ulcer healing in rats. J Pharmacol Exp Ther. 2003;307:692-698.
25. Filaretova LP, Podvigina TT, Bagaeva TR, Tanaka A, Takeuchi K. Mechanisms underlying the gastroprotective action of glucocorticoids released in response to ulcerogenic stress factors. Ann NY Acad Sci. 2004;1018:288-292.
26. Filaretova LP, Bagaeva TR, Podvigina TT, Morozova OI. Deficiency of glucocorticoid production delays the healing of acute gastric mucosal erosion and chronic ulcers in rats. Ross Fiziol Zh Im I M Sechenova. 2003;89:1137-1146.
27. Conn HO, Poynard T. Corticosteroids and peptic ulcer: meta-analysis of adverse events during steroid therapy. J Intern Med. 1994;236:619-632.
28. Heidelbaugh JJ, Inadomi JM. Magnitude and economic impact of inappropriate use of stress ulcer prophylaxis in non-ICU hospitalized patients. Am J Gastroenterol. 2006;101:2200-2205.
29. Hwang KO, Kolarov S, Cheng L, Griffith RA. Stress ulcer prophylaxis for non-critically ill patients on a teaching service. J Eval Clin Pract. 2007;13:716-721.
30. Liberman JD, Whelan CT. Brief report: reducing inappropriate usage of stress ulcer prophylaxis among internal medicine residents. A practice-based educational intervention. J Gen Intern Med. 2006;21:498-500.
31. Pitimana-aree S, Forrest D, Brown G, Anis A, Wang XH, Dodek P. Implementation of a clinical practice guideline for stress ulcer prophylaxis increases appropriateness and decreases cost of care. Intensive Care Med. 1998;24:217-223.