What is the ED95 of prilocaine for femoral nerve block using ultrasound?

British Journal of Anaesthesia

Volumn 110, Issue 5, 2013, Pages 831-836

  Gupta, P K ^a,b   Chevret, S ^c   Zohar, S ^c   Hopkins, P M ^a,b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

anaesthetic techniques; anaesthetics local; dose response; monitoring; pharmacology; prilocaine; regional; statistics; ultrasound

Indexed keywords

ATROPINE; PRILOCAINE; PROPOFOL; LOCAL ANESTHETIC AGENT;

ADULT; AGED; ARTICLE; BRADYCARDIA; CLINICAL ARTICLE; CLINICAL ASSESSMENT; DOSE CALCULATION; FEMALE; FEMORAL NERVE; HUMAN; HUMAN TISSUE; MALE; MALIGNANT HYPERTHERMIA; MUSCLE BIOPSY; NERVE BLOCK; PRIORITY JOURNAL; REAL TIME ECHOGRAPHY; SINGLE BLIND PROCEDURE; VASTUS MEDIALIS MUSCLE; BIOPSY; DOSE RESPONSE; ECHOGRAPHY; ENDOSCOPIC ECHOGRAPHY; METHODOLOGY; MIDDLE AGED; PATHOLOGY; QUADRICEPS FEMORIS MUSCLE;

ADULT; AGED; ANESTHETICS, LOCAL; BIOPSY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FEMORAL NERVE; HUMANS; MALE; MALIGNANT HYPERTHERMIA; MIDDLE AGED; NERVE BLOCK; PRILOCAINE; QUADRICEPS MUSCLE; ULTRASONOGRAPHY, INTERVENTIONAL; YOUNG ADULT;

MLCS; MLOWN;

EID: 84876522958     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aes503     Document Type: Article

References (28)

1. Fournier R, Van Gessel E, Gaggero G, Boccovi S, Forster A, Gamulin Z. Postoperative analgesia with '3-in-1' femoral nerve block after prosthetic hip surgery. Can J Anaesth 1998; 45: 34-8
2. Taylor EW, Fielding JW, Keighley MR, Alexander-Williams J. Long saphenous vein stripping under local anaesthesia. Ann R Coll Surg Engl 1981; 63: 206-7
3. Rasiah R, Azlina AA, Merican NT. Single injection of femoral nerve block for bilateral total knee arthroplasty for post-operative pain management. Br J Anaesth 2012; 108 (Suppl. 2): ii411
4. Carli F, Clemente A, Asenjo JF, et al. Analgesia and functional outcome after total knee arthroplasty: periarticular infiltration vs continuous femoral nerve block. Br J Anaesth 2010; 105: 185-95
5. Fowler SJ, Symons J, Sabato S, Myles PS. Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials. Br J Anaesth 2008; 100: 154-64
6. Madej TH, Ellis FR, Halsall PJ. Evaluation of '3 in 1' lumbar plexus block in patients havingmuscle biopsy. Br J Anaesth 1989; 62: 515-7
7. O'Quigley J, Pepe M, Fisher L. Continual reassessment method: a practical design for phase 1 clinical trials in cancer. Biometrics 1990; 46: 33-48
8. Resche-Rigon M, Zohar S, Chevret S. Adaptive designs for dosefinding in non-cancer phase II trials: influence of early unexpected outcomes. Clin Trials 2008; 5: 595-606
9. Zohar S, Resche-Rigon M, Chevret S. Using the continual reassessment method to estimate the minimum effective dose in phase II dose-finding studies: a case study. Clin Trials 2011; 0: 1-8
10. Zohar S, Chevret S. The continual reassessment method: comparison of Bayesian stopping rules for dose-ranging studies. Stat Med 2001; 20: 2827-43
11. R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical, version 2.10.1, 2009. Available from http://www.R-project.org
12. Dixon WJ, Massey FJ. Introduction to Statistical Analysis, 2nd Edn. New York: McGraw-Hill Book Co., 1957
13. Dixon WJ, Mood AM. A method for obtaining and analyzing sensitivity data. J Am Stat Assoc 1948; 43: 109-26
14. Dixon WJ. The up-and-down method for small samples. J Am Stat Assoc 1965; 60: 967-78
15. Treluyer JM, Zohar S, Rey E, et al. Minimum effective dose of midazolam for sedation of mechanically ventilated neonates. J Clin Pharm Thera 2005; 30: 479-85
16. Desfrere L, Zohar S, Morville P, et al. Dose-finding study of ibuprofen in patent ductus arteriosus using the continual reassessment method. J Clin Pharm Ther 2005; 30: 121-32
17. Grossman SA, Carson KA, Phuphanich S, et al. Phase I and pharmacokinetic study of karenitecin in patients with recurrent malignant gliomas. Neuro Oncol 2008; 10: 608-16
18. Mathew P, Thall PF, Jones D, et al. Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer. J Clin Oncol 2004; 22: 3323-9
19. Eder JP Jr, Garcia-Carbonero R, Clark JW, et al. A phase I trial of daily oral 4'- N-benzoyl-staurosporine in combination with protracted continuous infusion 5-fluorouracil in patients with advanced solid malignancies. Invest New Drugs 2004; 22: 139-50
20. Kant A, Gupta PK, Zohar S, Chevret S, Hopkins PM. Application of the continual reassessment method to dose-finding studies in regional anesthesia: an estimate of the ED95 dose for 0.5% bupivacaine for ultrasound-guided supraclavicular block. Anesthesiology 2013, in press
21. Abrahams MS, Aziz MF, Fu RF, Horn JL. Ultrasound guidance compared with electrical neurostimulation for peripheral nerve block: a systematic review and meta-analysis of randomized controlled trials. Br J Anaesth 2009; 102: 408-17
22. Baciarello M, Danelli G, Fanelli G. Real-time ultrasound visualization of intravascular injection of local anesthetic during a peripheral nerve block. Reg Anesth Pain Med 2009; 34: 278-9
23. Sutin KM, Schneider C, Sandhu NS, Capan LM. Deep venous thrombosis revealed during ultrasound-guided femoral nerve block. Br J Anaesth 2005; 94: 247-8
24. Casati A, Baciarello M, Di Cianni S, et al. Effects of ultrasound guidance on the minimum effective anaesthetic volume required to block the femoral nerve. Br J Anaesth 2007; 98: 823-7
25. Marhofer P, Harrop-Griffiths W, Kettner SC, Kirchmair L. Fifteen years of ultrasound guidance in regional anaesthesia: part 1. Br J Anaesth 2010; 104: 538-46
26. Marhofer P, Harrop-Griffiths W, Willschke H, Kirchmair L. Fifteen years of ultrasound guidance in regional anaesthesia: Part 2- recent developments in block techniques. Br J Anaesth 2010; 104: 673-83
27. Gupta PK, Pace NL, Hopkins PM. Effect of body mass index on the ED50 volume of bupivacaine 0.5% for supraclavicular brachial plexus block. Br J Anaesth 2010; 104: 490-5
28. Bigeleisen PE. Nerve puncture and apparent intraneural injection during ultrasound-guided axillary block does not invariably result in neurologic injury. Anesthesiology 2006; 105: 779-83