Composition and diversity of the duodenal mucosa-associated microbiome in children with untreated coeliac disease

Scandinavian Journal of Gastroenterology

Volumn 48, Issue 5, 2013, Pages 530-536

  De Meij, Tim G J ^a   Budding, Andries E ^a   Grasman, Mathijs E ^a   Kneepkens, C M Frank ^a   Savelkoul, Paul H M ^a   Mearin, M Luisa ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Coeliac disease; Duodenal mucosa associated microbiome; IS pro; Pathogenesis

Indexed keywords

ADOLESCENT; ARTICLE; CELIAC DISEASE; CHILD; CLINICAL ARTICLE; CLOSTRIDIUM; CONTROLLED STUDY; DUODENUM BIOPSY; DUODENUM MUCOSA; FEMALE; HUMAN; INTESTINE BIOPSY; INTESTINE FLORA; LACTOBACILLUS REUTERI; MALE; MICROBIAL DIVERSITY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; STREPTOCOCCUS;

ADOLESCENT; BIOPSY; CASE-CONTROL STUDIES; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; CLOSTRIDIUM; DNA PRIMERS; DNA, BACTERIAL; DUODENUM; FEMALE; HUMANS; INTESTINAL MUCOSA; LACTOBACILLUS REUTERI; MALE; METAGENOME; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; STREPTOCOCCUS;

EID: 84876497585     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2013.775666     Document Type: Article

References (29)

1. Armstrong MJ, Robins GG, Howdle PD. Recent advances in coeliac disease. Curr Opin Gastroenterol 2009;25: 100-9.
2. Mearin ML. Celiac disease among children and adolescents. Curr Probl Pediatr Adolesc Health Care 2007;37:86-105.
3. Fasano A, Catassi C. Coeliac disease in children. Best Pract Res Clin Gastroenterol 2005;19:467-78. (Pubitemid 40753766)
4. Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, et al. European society for pediatric gastroenterology, hepatology, and nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012;54:136-60.
5. Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, et al. Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 2010;42: 295-302.
6. Sollid LM, Lundin KE. Diagnosis and treatment of celiac disease. Mucosal Immunol 2009;2:3-7.
7. Forsberg G, Fahlgren A, Hörstedt P, Hammarström S, Hernell O, Hammarström ML, et al. Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease. Am J Gastroenterol 2004;99:894-904. (Pubitemid 39090220)
8. Stene LC, Honeyman MC, Hoffenberg EJ, Haas JE, Sokol RJ, Emery L, et al. Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol 2006;101:2333-40. (Pubitemid 44477562)
9. Collado MC, Calabuig M, Sanz Y. Differences between the fecal microbiota of coeliac infants and healthy controls. Curr Issues Intest Microbiol 2007;8:9-14. (Pubitemid 46604951)
10. Schippa S, Iebba V, Barbato M, Di Nardo G, Totino V, Checchi MP, et al. A distinctive 'microbial signature' in celiac pediatric patients. BMC Microbiol 2010;10:175.
11. Ou G, Hedberg M, Hörstedt P, Baranov V, Forsberg G, Drobni M, et al. Proximal small intestinal microbiota and identification of rod-shaped bacteria associated with childhood celiac disease. Am J Gastroenterol 2009;104:3058-67.
12. Collado MC, Donat E, Ribes-Koninckx C, Calabuig M, Sanz Y. Specific duodenal and faecal bacterial groups associated with paediatric coeliac disease. J Clin Pathol 2009;62: 264-9.
13. Tannock GW, Munro K, Harmsen HJ, Welling GW, Smart J, Gopal PK. Analysis of the fecal microflora of human subjects consuming a probiotic product containing Lactoba-cillus rhamnosus DR20. Appl Environ Microbiol 2000;66: 2578-88. (Pubitemid 30353968)
14. Budding AE, Grasman ME, Lin F, Bogaards JA, Soeltan-Kaersenhout DJ, Vandenbroucke-Grauls CM, et al. IS-pro: high-throughput molecular fingerprinting of the intestinal microbiota. FASEB J 2010;24:4556-64.
15. Csizmadia CG, Mearin ML, von Blomberg BM, Brand R, Verloove-Vanhorick SP. An iceberg of childhood coeliac disease in the Netherlands. Lancet 1999;353:813-14. (Pubitemid 29110416)
16. van Koppen EJ, Schweizer JJ, Csizmadia CG, Krom Y, Hylkema HB, van Geel AM, et al. Long-term health and quality-of-life consequences of mass screening for childhood celiac disease: a 10-year follow-up study. Pediatrics 2009; 123:582-8.
17. Marsh MN, Crowe PT. Morphology of the mucosal lesion in gluten sensitivity. Baillieres Clin Gastroenterol 1995;9:273-93.
18. Tjellström B, Stenhammar L, Högberg L, Fälth-Magnusson K, Magnusson KE, Midtvedt T, et al. Gut microflora associated characteristics in children with celiac disease. Am J Gastroenterol 2005;100:2784-8.
19. Sanz Y, Sánchez E, Marzotto M, Calabuig M, Torriani S, Dellaglio F. Differences in faecal bacterial communities in coeliac and healthy children as detected by PCR and denaturing gradient gel electrophoresis. FEMS Immunol Med Microbiol 2007;51:562-8. (Pubitemid 350076169)
20. Di Cagno R, De Angelis M, De Pasquale I, Ndagijimana M, Vernocchi P, Ricciuti P, et al. Duodenal and faecal micro-biota of celiac children: molecular, phenotype and metabo-lome characterization. BMC Microbiol 2011;4:219.
21. Nistal E, Caminero A, Vivas S, Ruiz de Morales JM, Sáenz de Miera LE, Rodríguez-Aparicio LB, et al. Differences in faecal bacteria populations and faecal bacteria metabolism in healthy adults and celiac disease patients. Biochimie 2012;94:1724-9.
22. Sánchez E, Ribes-Koninckx C, Calabuig M, Sanz Y. Intestinal Staphylococcus spp. and virulent features associated with coeliac disease. J Clin Pathol 2012;65:830-4.
23. Wang M, Ahrné S, Jeppsson B, Molin G. Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S rRNA genes. FEMS Micro-biol Ecol 2005;54:219-31. (Pubitemid 41317922)
24. Ivarsson A, Persson LA, Nyström L, Ascher H, Cavell B, Danielsson L, et al. Epidemic of coeliac disease in Swedish children. Acta Paediatr 2000;89:165-71. (Pubitemid 30339587)
25. Hogen Esch CE, Rosén A, Auricchio R, Romanos J, Chmielewska A, Putter H, et al. The Prevent CD study design: towards new strategies for the prevention of coeliac disease. Eur J Gastroenterol Hepatol 2010;22:1424-30.
26. Nadal I, Donat E, Ribes-Koninckx C, Calabuig M, Sanz Y. Imbalance in the composition of the duodenal microbiota of children with coeliac disease. J Med Microbiol 2007;56: 1669-74. (Pubitemid 350276518)
27. Janda JM, Abbott SL. 16S rRNA gene sequencing for bacterial identification in the diagnostic laboratory: pluses, perils, and pitfalls. J Clin Microbiol 2007;45: 2761-4. (Pubitemid 47417311)
28. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, et al. Diversity of the human intestinal microbial flora. Science 2005;308:1635-8. (Pubitemid 40807514)
29. Kalliomäki M, Satokari R, Lähteenoja H, Vähämiko S, Grönlund J, Routi T, et al. Expression of microbiota, toll-like receptors, and their regulators in the small intestinal mucosa in celiac disease. J Pediatr Gastroenterol Nutr 2012;54: 727-32.