Resolution of defective dorsal aortae patterning in Sema3E-deficient mice occurs via angiogenic remodeling

Developmental Dynamics

Volumn 242, Issue 5, 2013, Pages 580-590

  Meadows, Stryder M ^a   Ratliff, Lyndsay A ^a   Singh, Manvendra K ^b   Epstein, Jonathan A ^b   Cleaver, Ondine ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Angiogenic remodeling; Avascular; Endothelial; Lateral plate mesoderm; Neuronal guidance cue; Notochord; Repulsive; Sema3E

Indexed keywords

SEMAPHORIN; SEMAPHORIN 3E; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ANOMALY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; DISEASE SEVERITY; DORSAL AORTA PATTERNING DEFECT; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEMAPHORIN 3E GENE;

ANIMALS; AORTA; BODY PATTERNING; EMBRYO, MAMMALIAN; ENDOTHELIUM, VASCULAR; GESTATIONAL AGE; GLYCOPROTEINS; HEART DEFECTS, CONGENITAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PHYSIOLOGIC; TIME FACTORS;

MUS;

EID: 84876494502     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.23949     Document Type: Article

References (24)

1. Adams RH, Eichmann A. 2010. Axon guidance molecules in vascular patterning. Cold Spring Harb Perspect Biol 2:a001875.
2. Bedell VM, Yeo SY, Park KW, Chung J, Seth P, Shivalingappa V, Zhao J, Obara T, Sukhatme VP, Drummond IA, Li DY, Ramchandran R. 2005. roundabout4 is essential for angiogenesis in vivo. Proc Natl Acad Sci U S A 102:6373-6378.
3. Coffin JD, Harrison J, Schwartz S, Heimark R. 1991. Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo. Dev Biol 148:51-62.
4. Dickson BJ. 2002. Molecular mechanisms of axon guidance. Science 298:1959-1964.
5. Eichmann A, Makinen T, Alitalo K. 2005. Neural guidance molecules regulate vascular remodeling and vessel navigation. Genes Dev 19:1013-1021.
6. Gitler AD, Lu MM, Epstein JA. 2004. PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev Cell 7:107-116.
7. Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD. 2005. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science 307:265-268.
8. Helbling PM, Saulnier DM, Brandli AW. 2000. The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis. Development 127:269-278.
9. Hogan KA, Bautch VL. 2004. Blood vessel patterning at the embryonic midline. Curr Top Dev Biol 62:55-85.
10. Jones EA. 2011. The initiation of blood flow and flow induced events in early vascular development. Semin Cell Dev Biol 22:1028-1035.
11. Kigel B, Varshavsky A, Kessler O, Neufeld G. 2008. Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells. PloS one 3:e3287.
12. Kim J, Oh WJ, Gaiano N, Yoshida Y, Gu C. 2011. Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism. Genes Dev 25:1399-1411.
13. Lu X, Le Noble F, Yuan L, Jiang Q, De Lafarge B, Sugiyama D, Breant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A. 2004. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 432:179-186.
14. Meadows SM, Fletcher PJ, Moran C, Xu K, Neufeld G, Chauvet S, Mann F, Krieg PA, Cleaver O. 2012. Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Circ Res 110:34-46.
15. Mukouyama YS, Shin D, Britsch S, Taniguchi M, Anderson DJ. 2002. Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell 109:693-705.
16. Reese DE, Hall CE, Mikawa T. 2004. Negative regulation of midline vascular development by the notochord. Dev Cell 6:699-708.
17. Sakurai A, Gavard J, Annas-Linhares Y, Basile JR, Amornphimoltham P, Palmby TR, Yagi H, Zhang F, Randazzo PA, Li X, Weigert R, Gutkind JS. 2010. Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras. Mol Cell Biol 30:3086-3098.
18. Slack JM. 1991. From egg to embryo: regional specification in early development. New York: Cambridge University Press.
19. Stone J, Itin A, Alon T, Pe'er J, Gnessin H, Chan-Ling T, Keshet E. 1995. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci 15:4738-4747.
20. Suchting S, Bicknell R, Eichmann A. 2006. Neuronal clues to vascular guidance. Exp Cell Res 312:668-675.
21. Torres-Vazquez J, Gitler AD, Fraser SD, Berk JD, Van NP, Fishman MC, Childs S, Epstein JA, Weinstein BM. 2004. Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev Cell 7:117-123.
22. Wang HU, Chen ZF, Anderson DJ. 1998. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93:741-753.
23. Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA. 2009. Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol 325:82-93.
24. Zygmunt T, Gay CM, Blondelle J, Singh MK, Flaherty KM, Means PC, Herwig L, Krudewig A, Belting HG, Affolter M, Epstein JA, Torres-Vazquez J. 2011. Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1. Dev Cell 21:301-314.