The assessment of vertebral fractures in elderly women with recent hip fractures: The BREAK Study

Osteoporosis International

Volumn 24, Issue 4, 2013, Pages 1151-1159

  Gonnelli, S ^a   Caffarelli, C ^a   Maggi, S ^b   Rossi, S ^c   Siviero, P ^b   Gandolini, G ^d   Cisari, C ^e   Rossini, M ^f   Iolascon, G ^g   Letizia Mauro, G ^h   Crepaldi, G ^b   Nuti, R ^a  

^a UNIVERSITY HOSPITAL OF SIENA   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF SIENA   (Italy)

^d IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^e General Hospital   (Italy)

^f UNIVERSITY OF VERONA   (Italy)

^g UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^h UNIVERSITY OF PALERMO   (Italy)

Author keywords

Cervical fracture; Hip fracture; Spinal deformity index; Trochanteric fracture; Vertebral fracture

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; FAMILY HISTORY; FEMALE; FRAGILITY FRACTURE; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SPINE FRACTURE; SPINE RADIOGRAPHY;

AGED; AGED, 80 AND OVER; FEMALE; HIP FRACTURES; HUMANS; ITALY; LIFE STYLE; LUMBAR VERTEBRAE; MIDDLE AGED; OSTEOPOROTIC FRACTURES; PREVALENCE; SEVERITY OF ILLNESS INDEX; SPINAL FRACTURES; THORACIC VERTEBRAE; WALKING;

EID: 84876468030     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-012-2119-2     Document Type: Article

References (38)

1. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis and Therapy (2001) Osteoporosis prevention, diagnosis and therapy. JAMA 285:785-795
2. Cooper C, Atkinson EJ, O'Fallon WM, Melton LJ 3rd (1992) Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985-1989. J Bone Miner Res 7:221-227
3. Gullberg B, Johnell O, Kanis JA (1997) World-wide projections for hip fracture. Osteoporos Int 7:407-413
4. Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761-1767
5. Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA 3rd, Berger M (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15:721-739
6. Black DM, Arden NK, Palermo L, Pearson J, Cummings SR (1999) Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures Study of Osteoporotic Fractures Research Group. J Bone Miner Res 14:821-828
7. Ismail AA, Cockerill W, Cooper C, Finn JD, Abendroth K, Parisi G et al (2001) Prevalent vertebral deformity predicts incident hip though not distal forearm fracture: results from the European Prospective Osteoporosis Study. Osteoporos Int 12:85-90
8. Chen JS, Cameron ID, Simpson JM, Seibel MJ, March LM, Cumming RG et al (2011) Low-trauma fractures indicate increased risk of hip fracture in frail older people. J Bone Miner Res 26:428-433
9. Johnell O, Oden A, Caulin F, Kanis JA (2001) Acute and long-term increase in fracture risk after hospitalization for vertebral fracture. Osteoporos Int 12:207-214
10. Hasserius R, Johnell O, Nilsson BE, Thorngren KG, Jonsson K, Mellström D et al (2003) Hip fracture patients have more vertebral deformities than subjects in population-based studies. Bone 32:180-184
11. Schousboe JT, Fink HA, Lui LY, Taylor BC, Ensrud KE (2006) Association between prior non-spine non-hip fractures or prevalent radiographic vertebral deformities known to be at least 10 years old and incident hip fracture. J Bone Miner Res 21:1557-1564
12. Puisto V, Heliövaara M, Impivaara O, Jalanko T, Kröger H, Knekt P et al (2011) Severity of vertebral fracture and risk of hip fracture: a nested case-control study. Osteoporos Int 22:63-68
13. Ferrar L, Roux C, Reid DM, Felsenberg D, Glüer CC, Eastell R (2012) Prevalence of non-fracture short vertebral height is similar in premenopausal and postmenopausal women: the osteoporosis and ultrasound study. Osteoporos Int 23:1035-1040
14. Pulkkinen P, Glüer CC, Jämsä T (2011) Investigation of differences between hip fracture types: a worthy strategy for improved risk assessment and fracture prevention. Bone 49:600-604
15. Kotowicz MA, Melton LJ 3rd, Cooper C, Atkinson EJ, O'Fallon WM, Riggs BL (1994) Risk of hip fracture in women with vertebral fracture. J Bone Miner Res 9:599-605
16. Mautalen CA, Vega EM, Einhorn TA (1996) Are the aetiologies of cervical and trochanteric hip fractures different? Bone 18:133S-137S
17. Schott AM, Hans D, Duboeuf F, Dargent-Molina P, Hajri T, Bréart G, Meunier PJ, EPIDOS Study Group (2005) Quantitative ultrasound parameters as well as bone mineral density are better predictors of trochanteric than cervical hip fractures in elderly women. Results from the EPIDOS study. Bone 37:858-863
18. Jokinen H, Pulkkinen P, Korpelainen J, Heikkinen J, Keinänen- Kiukaanniemi S, Jämsä T, Korpelainen R (2010) Risk factors for cervical and trochanteric hip fractures in elderly women: a population-based 10-year follow-up study. Calcif Tissue Int 87:44-51
19. Haentjens P, Autier P, Barette M, Venken K, Vanderschueren D, Boonen S, Hip Fracture Study Group (2007) Survival and functional outcome according to hip fracture type: a one-year prospective cohort study in elderly women with an intertrochanteric or femoral neck fracture. Bone 41:958-964
20. Fisher A, Srikusalanukul W, Davis M, Smith P (2010) Hip fracture type: important role of parathyroid hormone (PTH) response to hypovitaminosis D. Bone 47:400-407
21. Stewart A, Porter RW, Primrose WR, Walker LG, Reid DM (1999) Cervical and trochanteric hip fractures: bone mass and other parameters. Clin Rheumatol 18:201-206
22. Partanen J, Heikkinen J, Jämsä T, Jalovaara P (2002) Characteristics of lifetime factors, bone metabolism, and bone mineral density in patients with hip fracture. J Bone Miner Metab 20:367-375
23. Maggi S, Siviero P, Gonnelli S, Caffarelli C, Gandolini G, Cisari C, Break Study Group et al (2011) The burden of previous fractures in hip fracture patients. The Break Study. Aging Clin Exp Res 23:183-186
24. Genant HK, Wu CY, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8:1137-1148
25. Crans GG, Genant HK, Krege JH (2005) Prognostic utility of a semiquantitative spinal deformity index. Bone 37:175-179
26. Kerkeni S, Kolta S, Fechtenbaum J, Roux C (2009) Spinal deformity index (SDI) is a good predictor of incident vertebral fractures. Osteoporos Int 20:1547-1552
27. Sosa HM, Saavedra SP, grupo de trabajo en osteoporosis de la Sociedad Española de Medicina Interna (SEMI) (2007) Prevalence of vertebral fractures in hip fracture patients. Rev Clin Esp 207:464-468
28. Di Monaco M, Vallero F, Di Monaco R, Franza G, Tappero R (2011) The burden of prevalent vertebral fractures is negatively associated with functional outcome in women with hip fracture. Am J Phys Med Rehabil 90:1-7
29. Tosteson AN, Gabriel SE, Grove MR, Moncur MM, Kneeland TS, Melton LJ 3rd (2001) Impact of hip and vertebral fractures on quality-adjusted life years. Osteoporos Int 12:1042-1049
30. Jackson SA, Tenenhouse A, Robertson L (2000) Vertebral fracture definition from population-based data: preliminary results from the Canadian Multicenter Osteoporosis Study (CaMos). Osteoporos Int 11:680-687
31. Nevitt MC, Ross PD, Palermo L, Musliner T, Genant HK, Thompson DE (1999) Association of prevalent vertebral fractures, bone density, and alendronate treatment with incident vertebral fractures: effect of number and spinal location of fractures. The Fracture Intervention Trial Research Group. Bone 25:613-619
32. Baudoin C, Fardellone P, Sebert JL (1993) Effect of sex and age on the ratio of cervical to trochanteric hip fracture. A meta-analysis of 16 reports on 36,451 cases. Acta Orthop Scand 64:647-653
33. Gnudi S, Ripamonti C, Lisi L, Fini M, Giardino R, Giavaresi G (2002) Proximal femur geometry to detect and distinguish femoral neck fractures from trochanteric fractures in postmenopausal women. Osteoporos Int 13:69-73
34. Fox KM, Cummings SR, Williams E, Stone K, Study of Osteoporotic Fractures (2000) Femoral neck and intertrochanteric fractures have different risk factors: a prospective study. Osteoporos Int 11:1018-1023
35. Delmas PD, Genant HK, Crans GG, Stock JL, Wong M, Siris E, Adachi JD (2003) Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial. Bone 33:522-532
36. Genant HK, Delmas PD, Chen P, Jiang Y, Eriksen EF, Dalsky GP et al (2007) Severity of vertebral fracture reflects deterioration of bone microarchitecture. Osteoporos Int 18:69-76
37. Netelenbos JC, Lems WF, Geusens PP, Verhaar HJ, Boermans AJ et al (2009) Spine radiographs to improve the identification of women at high risk for fractures. Osteoporos Int 20:1347-1352
38. Schwartz AV, Sellmeyer DE, Ensrud KE, Cauley JA, Tabor HK, Schreiner PJ, Jamal SA, Black DM, Cummings SR, Study of Osteoporotic Features Research Group (2001) Older women with diabetes have an increased risk of fracture: a prospective study. J Clin Endocrinol Metab 86:32-38