Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis

BioFactors

Volumn 39, Issue 2, 2013, Pages 221-232

  Murakami, Akira ^a   Furukawa, Ikuyo ^a   Miyamoto, Shingo ^a,d   Tanaka, Takuji ^b,c   Ohigashi, Hajime ^a,e  

^a KYOTO UNIVERSITY   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c The Tohkai Cytopathology Institute: Cancer Research and Prevention (TCI CaRP) 4 33 Minami Uzura   (Japan)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^e Fukui Prefecture University   (Japan)

Author keywords

Chemoprevention; Colitis; Colorectal cancer; MRNA stability; Turmeric

Indexed keywords

AR TURMERONE; CURCUMIN; CYCLOOXYGENASE 2; DACTINOMYCIN; DEXTRAN SULFATE; ESSENTIAL OIL; HUR PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; SESQUITERPENE; TURMERONE; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ADENOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PREVENTION; COLITIS; COLON CARCINOGENESIS; CONTROLLED STUDY; FEMALE; INFLAMMATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE; COLITIS; COLONIC NEOPLASMS; CURCUMA; CURCUMIN; FEMALE; KETONES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED ICR; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SESQUITERPENES;

CURCUMA LONGA;

EID: 84876445539     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.1054     Document Type: Article

References (42)

1. Lashner, B., Provencher, K., Bozdech, J., and Brzezinski, A. ( 1995) Worsening risk for the development of dysplasia or cancer in patients with chronic ulcerative colitis. Am. J. Gastroenterol. 90, 377-380.
2. Akgun, E., Caliskan, C., Celik, H., Ozutemiz, A., Tuncyurek, M., et al. ( 2005), Effects of N-acetylcysteine treatment on oxidative stress in acetic acid-induced experimental colitis in rats. J. Int. Med. Res. 33, 196-206.
3. Damiani, C., Benetton, C., Stoffel, C., Bardini, K., Cardoso, V., et al. ( 2007) Oxidative stress and metabolism in animal model of colitis induced by dextran sulfate sodium. J. Gastroenterol. Hepatol. 22, 1846-1851.
4. Suzuki, R., Kohno, H., Sugie, S., and Tanaka, T. ( 2004) Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate. Cancer Sci. 95, 721-727.
5. Bing, R., Miyataka, M., Rich, K., Hanson, N., Wang, X., et al. ( 2001) Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer. Clin. Cancer Res. 7, 3385-3392.
6. Surh, Y. and Chun, K. ( 2007) Cancer chemopreventive effects of curcumin. Adv. Exp. Med. Biol. 595, 149-172.
7. Huang, M., Lou, Y., Ma, W., Newmark, H., Reuhl, K., et al. ( 1994) Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. Cancer Res. 54, 5841-5847.
8. Kawamori, T., Lubet, R., Steele, V., Kelloff, G., Kaskey, R., et al. ( 1999) Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res. 59, 597-601.
9. Kim, J., Araki, S., Kim, D., Park, C., Takasuka, N., et al. ( 1998) Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1, 2-dimethylhydrazine initiation. Carcinogenesis 19, 81-85.
10. Mahmoud, N., Carothers, A., Grunberger, D., Bilinski, R., Churchill, M., et al. ( 2000) Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis. Carcinogenesis 21, 921-927.
11. Rao, C., Rivenson, A., Simi, B., and Reddy, B. ( 1995) Chemoprevention of colon cancer by dietary curcumin. Ann. NY Acad. Sci. 768, 201-204.
12. Surh, Y., Chun, K., Cha, H., Han, S., Keum, Y., et al. ( 2001) Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat. Res. 480-481, 243-268.
13. Camacho-Barquero, L., Villegas, I., Sánchez-Calvo, J., Talero, E., Sánchez-Fidalgo, S., et al. ( 2007) Alarcón de la Lastra, Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis. Int. Immunopharmacol. 7, 333-342.
14. Ma, X. and Gang, D. ( 2006) Metabolic profiling of turmeric (Curcuma longa L.) plants derived from in vitro micropropagation and conventional greenhouse cultivation. J. Agric. Food Chem. 54, 9573-9583.
15. Negi, P., Jayaprakasha, G., Jagan Mohan Rao, L., and Sakariah, K. ( 1999) Antibacterial activity of turmeric oil: a byproduct from curcumin manufacture. J. Agric. Food Chem. 47, 4297-4300.
16. Kuroda, M., Mimaki, Y., Nishiyama, T., Mae, T., Kishida, H., et al. ( 2005) Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice. Biol. Pharm. Bull. 28, 937-939.
17. Murakami, A., Ishida, H., Kobo, K., Furukawa, I., Ikeda, Y., et al. ( 2005) Suppressive effects of Okinawan food items on free radical generation from stimulated leukocytes and identification of some active constituents: implications for the prevention of inflammation-associated carcinogenesis. Asian Pac. J. Cancer Prev. 6, 437-448.
18. Ji, M., Choi, J., Lee, J., and Lee, Y. ( 2004) Induction of apoptosis by ar-turmerone on various cell lines. Int. J. Mol. Med. 14, 253-256.
19. Kohno, H., Suzuki, R., Curini, M., Epifano, F., Maltese, F., et al. ( 2006) Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. Int. J. Cancer 118, 2936-2942.
20. van der Woude, C., Kleibeuker, J., Jansen, P., and Moshage, H. ( 2004) Chronic inflammation, apoptosis and (pre-)malignant lesions in the gastro-intestinal tract. Apoptosis 9, 123-130.
21. Divya, C. S. and Pillai, M. R. ( 2006) Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis. Mol. Carcinog. 45, 320-332.
22. Dean, J. L., Sully, G., Clark, A. R., and Saklatvala, J. ( 2004) The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation. Cell Signal. 16, 1113-1121.
23. Doller, A., Huwiler, A., Müller, R., Radeke, H., Pfeilschifter, J., et al. ( 2007) Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Mol. Biol. Cell 18, 2137-2148.
24. Ohigashi, H. and Murakami, A. ( 2004) Cancer prevention with food factors: alone and in combination. Biofactors 22, 49-55.
25. Tanaka, T., Kohno, H., Suzuki, R., Yamada, Y., Sugie, S., et al. ( 2003) A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci. 94, 965-973.
26. Levin, B., Lieberman, D., McFarland, B., Andrews, K., Brooks, D., et al. ( 2008) Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology 134, 1570-1595.
27. Kuriki, K. and Tajima, K. ( 2006) The increasing incidence of colorectal cancer and the preventive strategy in Japan. Asian Pac. J. Cancer Prev. 7, 495-501.
28. Kim, Y. S. and Milner, J. A. ( 2007) Dietary modulation of colon cancer risk. J. Nutr. 137, 2576S-2579S.
29. Aggarwal, B. B., Kunnumakkara, A. B., Harikumar, K. B., Tharakan, S. T., Sung, B., et al. ( 2008) Potential of spice-derived phytochemicals for cancer prevention. Planta. Med. 74, 1560-1569.
30. Lao, C. D., Ruffin, M. T. t., Normolle, D., Heath, D. D., Murray, S. I., et al. ( 2006) Dose escalation of a curcuminoid formulation. BMC Complement Altern. Med. 6, 10.
31. Kwon, K., Ohigashi, H., and Murakami, A. ( 2007) Dextran sulfate sodium enhances interleukin-1 beta release via activation of p38 MAPK and ERK1/2 pathways in murine peritoneal macrophages. Life Sci. 81, 362-371.
32. Ohama, T., Hori, M., Momotani, E., Elorza, M., Gerthoffer, W., et al. ( 2007) IL-1beta inhibits intestinal smooth muscle proliferation in an organ culture system: involvement of COX-2 and iNOS induction in muscularis resident macrophages. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G1315-G1322.
33. Kohno, H., Suzuki, R., Sugie, S., and Tanaka, T. ( 2005) Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1, 2-dimethylhydrazine and dextran sodium sulfate. Cancer Sci. 96, 69-76.
34. Xiao, H. and Yang, C. ( 2008) Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. Int. J. Cancer 123, 983-990.
35. Aggarwal, B. B. and Shishodia, S. ( 2004) Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning. Ann. NY Acad. Sci. 1030, 434-441.
36. Brennan, C. and Steitz, J. ( 2001) HuR and mRNA stability. Cell Mol. Life. Sci. 58, 266-277.
37. Ortega, A., Sala, S., Espinosa, E., González-Barón, M., and Cuezva, J. ( 2008) HuR and the bioenergetic signature of breast cancer: a low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence. Carcinogenesis 29, 2053-2061.
38. Wang, J., Zhao, W., Guo, Y., Zhang, B., Xie, Q., et al. ( 2009) The expression of RNA-binding protein HuR in non-small cell lung cancer correlates with vascular endothelial growth factor-C expression and lymph node metastasis. Oncology 76, 420-429.
39. Yi, X., Zhou, Y., Zheng, W., and Chambers, S. ( 2009) HuR expression in the nucleus correlates with high histological grade and poor disease-free survival in ovarian cancer. Aust. NZ J. Obstet. Gynaecol. 49, 93-98.
40. Yoo, P., Sullivan, C., Kiang, S., Gao, W., Uchio, E., et al. ( 2009) Tissue microarray analysis of 560 patients with colorectal adenocarcinoma: high expression of HuR predicts poor survival. Ann. Surg. Oncol. 16, 200-207.
41. Young, L., Sanduja, S., Bemis-Standoli, K., Pena, E., Price, R., et al. ( 2009) The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology 136, 1669-1679.
42. Doller, A., Pfeilschifter, J., and Eberhardt, W. ( 2008) Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. Cell Signal. 20, 2165-2173.