The Outcome of Prophylactic Intravenous Cefazolin and Ceftriaxone in Cirrhotic Patients at Different Clinical Stages of Disease after Endoscopic Interventions for Acute Variceal Hemorrhage

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Wu, Cheng Kun ^a   Wang, Jing Houng ^a   Lee, Chen Hsiang ^a   Wu, Keng Liang ^a   Tai, Wei Chen ^a   Lu, Sheng Nan ^a   Hu, Tsung Hui ^a   Chuah, Seng Kee ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CEFAZOLIN; CEFTRIAXONE;

ACUTE VARICEAL HEMORRHAGE; ADULT; ARTICLE; BACTERIAL INFECTION; BLOOD CLOTTING PARAMETERS; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; ENDOSCOPIC SCLEROTHERAPY; ENDOSCOPIC SURGERY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; INFECTION PREVENTION; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; REBLEEDING TIME; RISK ASSESSMENT;

ACUTE DISEASE; ADMINISTRATION, INTRAVENOUS; AGED; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; CEFAZOLIN; CEFTRIAXONE; ESOPHAGEAL AND GASTRIC VARICES; FEMALE; GASTROINTESTINAL HEMORRHAGE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PNEUMONIA; RETROSPECTIVE STUDIES; SEPSIS; TREATMENT OUTCOME;

EID: 84876423790     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061666     Document Type: Article

References (25)

1. Rimola A, Bory F, Teres J, Perez-Ayuso RM, Arroyo V, et al. (1985) Oral, nonabsorbable antibiotics prevent infection in cirrhotics with gastrointestinal hemorrhage. Hepatology 5: 463-467.
2. Soriano G, Guarner C, Tomas A, Villanueva C, Torras X, et al. (1992) Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage. Gastroenterology 103: 1267-1272.
3. Pauwels A, Mostefa-Kara N, Debenes B, Degoutte E, Levy VG, (1996) Systemic antibiotic prophylaxis after gastrointestinal hemorrhage in cirrhotic patients with a high risk of infection. Hepatology 24: 802-806.
4. Bernard B, Grange JD, Khac EN, Amiot X, Opolon P, et al. (1999) Antibiotic prophylaxis for the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding: a meta-analysis. Hepatology 29: 1655-1661.
5. Fernandez J, Navasa M, Gomez J, Colmenero J, Vila J, et al. (2002) Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. Hepatology 35: 140-148.
6. Chavez-Tapia NC, Barrientos-Gutierrez T, Tellez-Avila F, Soares-Weiser K, Mendez-Sanchez N, et al. (2011) Meta-analysis: antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding- an updated Cochrane review. Alimentery Pharmacology and Therapeutics 34: 509-518.
7. Hou MC, Lin HC, Liu TT, Kuo BI, Lee FY, et al. (2004) Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomized trial. Hepatology 39: 746-753.
8. Wyke RJ, (1987) Problems of bacterial infection in patients with liver disease. Gut 28: 623-641.
9. Garcia-Tsao G, Sanyal AJ, Grace ND, Carey W, (2007) Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology 46: 922-938.
10. de Franchis R, Baveno V Faculty, (2010) Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. Journal of Hepatology 53: 762-768.
11. Fernandez J, Del Arbol LR, Gomez C, Durandez R, Serradilla R, et al. (2006) Norfloxacin vs Ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage. Gastroenterology 131: 1049-1056.
12. Bergeron MG, Brusch JL, Barza M, Weinstein L, (1973) Bactericidal activity and pharmacology of cefazolin. Antimicrob Agents Chemother 4: 396-401.
13. Xu HW, Wang JH, Tsai MS, Wu KL, Chiou SS, et al. (2011) The effects of cefazolin on cirrhotic patients with acute variceal hemorrhage after endoscopic interventions. Surgical Endoscopy 25: 2911-2918.
14. Hung CH, Lu SN, Wang JH, Lee CM, Chen TM, et al. (2003) Correlation between ultrasonographic and pathologic diagnoses of hepatitis B and C virus-related cirrhosis. Journal of Gastroenterology 38: 153-157.
15. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R, (1973) Transection of the oesophagus for bleeding oesophageal varices. British Journal of Surgery 60: 646-649.
16. CDC/NHSN Surveillance Definition of Healthcare-Associated Infection and Criteria for Specific Types of Infections in the Acute Care Setting (2013) CDC website 17: 1-58. Available: http://www.cdc.gov/nhsn/pdfs/pscmanual/17pscnosinfdef_current.pdf. Accessed 2013 March 20.
17. The North Italian Endoscopic Club for the Study, Treatment of Esophageal varices, (1988) Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. New England Journal Medicine 319: 983-989.
18. Soares-Weiser K, Brezis M, Tur-Kaspa R, Leibovici L, (2002) Antibiotic prophylaxis for cirrhotic patients with gastrointestinal bleeding. Cochrane Database Sysemict Review CD002907 Update in: Cochrane Database Systemic Review. 2010 (9): CD002907.
19. Blaise M, Pateron D, Trinchet JC, Levacher S, Beaugrand M, et al. (1994) Systemic antibiotic therapy prevents bacterial infection in cirrhotic patients with gastrointestinal hemorrhage. Hepatology 20: 34-38.
20. Hsieh WJ, Lin HC, Hwang SJ, Hou MC, Lee FY, et al. (1998) The effect of ciprofloxacin in the prevention of bacterial infection in patients with cirrhosis after upper gastrointestinal bleeding. American Journal of Gastroenterology 93: 962-966.
21. Selby WS, Norton ID, Pokorny CS, Benn RA, (1994) Bacteremia and bacterascites after endoscopic sclerotherapy for bleeding esophageal varices and prevention by intravenous cefotaxime: a randomized trial. Gastrointestinal Endoscopy 40: 680-684.
22. ASGE STANDARDS OF PRACTICE COMMITTEE, Banerjee S, Shen B, Baron TH, Nelson DB, et al (2008) Antibiotic prophylaxis for GI endoscopy. Gastrointestinal Endoscopy 67: 791-798.
23. Aldeyab MA, Harbarth S, Vernaz N, Kearney MP, Scott MG, et al. (2012) The impact of antibiotic use on the incidence and resistance pattern of ESBL-producing bacteria in primary and secondary healthcare settings. British Journal of Clinical Pharmacology 74: 171-179.
24. Lee J, Pai H, Kim YK, Kim NH, Eun BW, et al. (2007) Control of extended-spectrum b-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a children's hospital by changing antimicrobial agent usage policy. Journal of Antimicrobial Chemotherapy 60: 629-637.
25. Lin YT, Lo GH, Lai KH, Chen TA, Lin WJ, (2002) Prophylactic antibiotics in cirrhotics with upper gastrointestinal hemorrhage: a prospective, controlled trial. Zhonghua Yi Xue Za Zhi (Taipei) 65: 365-71.