Prophylactic antibiotics in cirrhotics with upper gastrointestinal hemorrhage: A prospective, controlled trial

Chinese Medical Journal (Taipei)

Volumn 65, Issue 8, 2002, Pages 365-371

  Lin, Ying Tsun ^a   Lo, Gin Ho ^a   Lai, Kwok Hung ^a   Chen, Tai An ^a   Lin, Whey Jen ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Antibiotic prophylaxis; Bacterial infection; Cirrhosis; UGI hemorrhage

Indexed keywords

ANTIBIOTIC AGENT; CEFALEXIN; CEFAZOLIN; HEMOGLOBIN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; ASCITES; BACTERIAL GROWTH; BACTERIAL INFECTION; BLOOD CULTURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; FEVER; GASTROINTESTINAL ENDOSCOPY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE COCCI; HEMOGLOBIN DETERMINATION; HOSPITALIZATION; HUMAN; INCIDENCE; LIFE EXPECTANCY; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEX DIFFERENCE; THORAX RADIOGRAPHY; UPPER GASTROINTESTINAL BLEEDING; URINE CULTURE;

ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; BACTERIAL INFECTIONS; CEFAZOLIN; CEPHALEXIN; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES;

EID: 0036702144     PISSN: 05781337     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Rimola A, Bory F, Teres J, Peres-Ayuso RM, Arroyo V, Rodes J. Oral nonabsorbable antibiotics prevent infection in cirrhotics with gastrointestinal hemorrhage. Hepatology 1985;5:463-7.
2. Soriano G, Guarner C, Tomas A, Villanueva C, Torras X, Gonzalez D, et al. Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage. Gastroenterology 1992;103:1267-72.
3. Blaise M, Pateron D, Trinchet JC, Levacher S, Beaugrand M, Pourriat JL. Systemic antibiotic therapy prevents bacterial infection in cirrhotic patients with gastrointestinal hemorrhage. Hepatology 1994;20:34-8.
4. Pauwels A, Mostefa-Kara N, Debenes B, Degoutte E, Levy VG. Systemic antibiotic prophylaxis after gastrointestinal hemorrhage in cirrhotic patients with a high risk of infection. Hepatology 1996;24:802-6.
5. Sabat M, Kolle L, Soriano G, Ortiz J, Pamplona J, Novella MT, et al. Parenteral antibiotic prophylaxis of bacterial infections does not improve cost-efficacy of oral norfloxacin in cirrhotic patients with gastrointestinal bleeding. Am J Gastroenterol 1998;93:2457-62.
6. Bernard B, Grange JD, Khac EN, Amiot X, Opolon P, Poynard T. Antibiotic prophylaxis for the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding: a meta-analysis. Hepatology 1999;29:1655-61.
7. Hsieh WJ, Lin HC, Hwang SJ, Hou MC, Lee FY, Chang FY, et al. The effect of ciprofloxacin in the prevention of bacterial infection in patients with cirrhosis after upper gastrointestinal bleeding. Am J Gastroenterol 1998;93:962-6.
8. Goulis J, Armonis A, Patch D, Sabin C, Greenslade L, Burroughs AK. Bacterial infection is independently associated with failure to control bleeding in cirrhotic patients with gastrointestinal hemorrhage. Hepatology 1998;27:1207-12.
9. Wyke RJ. Problems of bacterial infection in patients with liver disease. Gut 1987;28:623-41.
10. Bleichner G, Boulanger R, Squara P, Sollet JP, Parent A. Frequency of infections in cirrhotic patients presenting with acute gastrointestinal hemorrhage. Br J Surg 1986;73:724-6.
11. Fuhr U, Anders EM, Mahr G, Sorgel F, Staib AH. Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vito. Antimicrob Agents Chemother 1992;36:942-8.
12. Tokura Y, Seo N, Ohshima A, Yagi H, Furukawa F, Takigawa M. Lymphocyte stimulation test with drug-photomodified cells in patients with quinolone photosensitivity. J Dermatol Sci 1999;21:34-41.
13. Garlando F, Tauber MG, Joos B, Oelz O, Luthy R. Ciprofloxacin-induced hematuria. Infection 1985; 13:177-8.
14. Davey PG. Post-marketing surveillance of the quinolone: a view from Great Britain. Rev Infect Dis 1989; 11 (suppl 5): 1402-7.
15. Bertino J, Fish D. The safety profile of the fluoroquinolones. Clin Ther 2000;22:798-817.
16. Lo GH, Lai KH, Cheng JS, Hwu JH, Chang CF, Chen SM, et al. A prospective, randomized trial of sclerotherapy versus ligation in the management of bleeding esophageal varices. Hepatology 1995;22:466-71.
17. Lo GH, Lai KH, Cheng JS, Lin CK, Huang JS, Hsu PI, et al. Emergency banding ligation versus sclerotherapy for the control of active bleeding from esophageal varices. Hepatology 1997;25:1101-4.
18. Lai KH, Peng SN, Guo WS, Lee FY, Chang FY, Malik U, et al. Endoscopic injection for the treatment of bleeding ulcers: Local tamponade or drug effect? Endoscopy 1994;26:338-41.
19. Pugh RNH, Murry-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding varices. Br J Surg 1973;60:646-9.
20. Deschenes M, Villeneuve JP. Risk factors for the development of bacterial infections in hospitalized patients with cirrhosis. Am J Gastroenterol 1999;94:2193-7.
21. Rosa H, Silverio AO, Perini RF, Arruda CB. Bacterial infection in cirrhotic patients and its relationship with alcohol. Am J Gastroenterol 2000;95:1290-3.
22. Bac DJ, Marie SD, Siersema, Snobl J, Buuren HRV. Post-sclerotherapy bacterial peritonitis: a complication of sclerotherapy or of variceal bleeding? Am J Gastroenterol 1994;89:859-62.
23. Kulkarni SG, Parikh SS, Dhawan PS, Chachad H, Jambavalikar MB, Koppikar GV, et al. High frequency of bacteremia with endoscopic treatment of esophageal varices in advanced cirrhosis. Indian J Gastroenterol 1999;18:143-5.
24. Lin OS, Wu SS, Chen YY, Soon MS. Bacterial peritonitis after elective endoscopic variceal ligation: a prospective study. Am J Gastroenterol 2000;95:214-7.
25. Hsueh PR, Teng LJ, Yang PC, Ho SW, Luh KT. Indwelling device-related bacteria caused by serum-susceptible Campylobacter coli. J Clin Microbiol 1997;35:2178-80.
26. Haglind E, Wang D, Klein AS. Hepatic reticuloendothelial system dysfunction after intestinal ischemia-reperfusion. Shock 1996;5:72-5.
27. Kondo S, Wang D, Mayumi T, Klein AS, Bulkley GB. Effect of hemorrhagic shock and resuscitation upon hepatic phagocytic clearance and killing of circulating microorganisms. Shock 1996;5:106-11.
28. Shorvon PJ, Eykyn SJ, Cotton PB. Gastrointestinal instrumentation, bacteremia, and endocarditis. Gut 1983;24:1078-93.
29. Eisentein BI, Watkins V. Diseases caused by gram-negative enteric bacilli. In: Fauci AS, Longo DL, eds. Harrison's Principles of Internal Medicine. New York: McGraw-Hill, 1998:936-41.
30. Rouzi AA, Khalifa F, Ba'aqeel Hs, Al-Hamdan HS, Bondagji N. The routine use of cefazolin in cesarean section. Int J Gynecol Obstet 2000;69:107-12.
31. Christiano AP, Hollowell CMP, Kim H, Kim J, Patel R, Bales GT, et al. Double-blind randomized comparison of single-dose ciprofloxacin versus intravenous cefazolin in patients undergoing outpatient endourologic surgery. Urology 2000;55:182-5.
32. Offer C, Weuta H, Bodner E. Efficacy of perioperative prophylaxis with ciprofloxacin or cefazolin in colorectal surgery. Infection 1988;16(suppl 1):46-7.
33. Marroni M, Cao P, Fiorio M, Maghini M, Lenti M, Repetto A, et al. Prospective, randomized, double-blind trial comparing teicoplanin and cefazolin as antibiotic prophylaxis in prosthetic vascular surgery. Eur J Clin Microbiol 1999; 18:175-8.
34. Afessa B, Kubilis PS. Upper gastrointestinal bleeding in patients with hepatic cirrhosis: clinical course and mortality prediction. Am J Gastroenterol 2000;95:484-9.
35. del Olmo JA, Pena A, Serra MA, Wassel AH, Benages A, Rodrigo JM. Predictors of morbidity and mortality after the first episode of upper gastrointestinal bleeding in liver cirrhosis. J Hepatol 2000;32:19-24.
36. Bernard B, Cadranel JF, Valla D, Escolano S, Jarlier V, Opolon P. Prognostic significance of bacterial infection in bleeding cirrhotic patients: a prospective study. Gastroenterology 1995;108:1828-34.
37. Gines P, Quintero E, Arroyo V, Teres J, Bruguera M, Rimola A, et al. Compensated cirrhosis: natural history and prognostic factors. Hepatology 1987;7:122-8.