Integration of HIV care and treatment in primary health care centers and patient retention in central mozambique: A retrospective cohort study

Journal of Acquired Immune Deficiency Syndromes

Volumn 62, Issue 5, 2013, Pages

  Lambdin, Barrot H ^a,b   Micek, Mark A ^b,c   Sherr, Kenneth ^b,c   Gimbel, Sarah ^b,c   Karagianis, Marina ^d   Lara, Joseph ^d   Gloyd, Stephen S ^b,c   Pfeiffer, James ^b,c  

^a Pangaea Global AIDS Foundation   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c HEALTH ALLIANCE INTERNATIONAL   (United States)

^d MINISTRY OF HEALTH   (Mozambique)

Author keywords

Antiretroviral therapy; Attrition; Health system; Implementation research; Integration; Mozambique

Indexed keywords

EFAVIRENZ; LAMIVUDINE; STAVUDINE;

ADOLESCENT; ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; EXPERIENCE; FEMALE; FOLLOW UP; HEALTH CARE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOSPITAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MOZAMBIQUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK; RURAL AREA; URBAN AREA;

ADOLESCENT; ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; FEMALE; HIV; HIV INFECTIONS; HUMANS; MALE; MOZAMBIQUE; PATIENT ACCEPTANCE OF HEALTH CARE; RETROSPECTIVE STUDIES; RURAL POPULATION; URBAN POPULATION; YOUNG ADULT;

EID: 84876414811     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3182840d4e     Document Type: Article

References (28)

1. UNAIDS. AIDS at 30: nations at the crossroads. 2011. Available at: http://www.unaids.org/unaids-resources/aidsat30/aids-at-30.pdf. Accessed January 31, 2012.
2. WHO/UNAIDS. Global HIV/AIDS response-epidemic update and health sector progress towards universal access: progress report 2011. 2011 1-223. Available at: http://whqlibdoc.who.int/publications/2011/9789241502986-eng.pdf. February 2, 2012.
3. Pfeiffer J, Montoya P, Baptista AJ, et al. Integration of HIV/AIDS services into African primary health care: lessons learned for health system strengthening in Mozambique-a case study. J Int AIDS Soc. 2010; 13:3. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2828398&tool= pmcentrez&rendertype=abstract. Accessed January 31, 2012.
4. Stringer JSA, Zulu I, Levy J, et al. Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes. JAMA. 2006;296:782-793. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16905784. Accessed August 18, 2011.
5. Chan AK, Mateyu G, Jahn A, et al. Outcome assessment of decentralization of antiretroviral therapy provision in a rural district of Malawi using an integrated primary care model. Trop Med Int Health. 2010;15 (suppl 1):90-97. Available at: http://www.ncbi.nlm.nih.gov/pubmed/20586966. Accessed September 25, 2011.
6. Topp SM, Chipukuma JM, Giganti M, et al. Strengthening health systems at facility-level: feasibility of integrating antiretroviral therapy into primary health care services in lusaka, zambia. PloS one. 2010;5: e11522. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2903482&tool= pmcentrez&rendertype=abstract. Accessed October 2, 2011.
7. Deribe K, Hailekiros F, Biadgilign S, et al. Defaulters from antiretroviral treatment in Jimma University specialized hospital, Southwest Ethiopia. Trop Med Int Health. 2008;13:328-333. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18298607. Accessed December 15, 2011.
8. Zachariah R, Harries AD, Manzi M, et al. Acceptance of anti-retroviral therapy among patients infected with HIV and tuberculosis in rural Malawi is low and associated with cost of transport. PloS one. 2006;1:e121. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1762339&tool= pmcentrez&rendertype=abstract. Accessed September 30, 2011.
9. Yu JKL, Chen SC-C, Wang K-Y, et al. True outcomes for patients on antiretroviral therapy who are "lost to follow-up" in Malawi. Bull World Health Organ. 2007;85:550-554. Available at: http://www.pubmedcentral.nih. gov/articlerender.fcgi?artid=2636367&tool=pmcentrez&rendertype=abstract. Accessed February 8, 2012.
10. Massaquoi M, Zachariah R, Manzi M, et al. Patient retention and attrition on antiretroviral treatment at district level in rural Malawi. Trans R Soc Trop Med Hyg. 2009;103:594-600. Available at: http://www.ncbi.nlm.nih.gov/pubmed/ 19298993. Accessed September 19, 2011.
11. Spira TJ, Ellerbrock TV. Commentary on Greig et al, "Similar mortality and reduced loss to follow-up in integrated compared with vertical programs providing antiretroviral treatment in Sub-Saharan Africa". J Acquir Immune Defic Syndr. 2012;59:82-84. Available at: http://www.ncbi.nlm.nih. gov/pubmed/22330609. Accessed November 2, 2011.
12. Fredlund VG, Nash J. How far should they walk? Increasing antiretroviral therapy access in a rural community in northern KwaZulu-Natal, South Africa. J Infect Dis. 2007;196(suppl 3):S469-S473. Available at: http://www.ncbi.nlm.nih. gov/pubmed/18181696. Accessed February 8, 2012.
13. Bedelu M, Ford N, Hilderbrand K, et al. Implementing antiretroviral therapy in rural communities: the Lusikisiki model of decentralized HIV/AIDS care. J Infect Dis. 2007;196(suppl 3):S464-S468. Available at: http://jid.oxfordjournals.org/content/196/Supplement-3/S464.full. Accessed December 3, 2011.
14. Greig J, O'brien D, Ford N, et al. Similar mortality and reduced loss to follow-up in integrated compared with vertical programs providing antiretroviral treatment in sub-Saharan Africa. J Acquir Immune Defic Syndr. 2012;59:e92-e98. Available at: http://www.ncbi.nlm.nih.gov/pubmed/22134144. Accessed January 9, 2012.
15. Grépin KA. Leveraging HIV programs to deliver an integrated package of health services: some words of caution. J Acquir Immune Defic Syndr. 2011;57(suppl 2):S77-S79. Available at: http://www.ncbi.nlm.nih.gov/pubmed/ 21857301. Accessed January 12, 2012.
16. Atun R, de Jongh T, Secci F, et al. A systematic review of the evidence on integration of targeted health interventions into health systems. Health policy Plan. 2010;25:1-14. Available at: http://www.ncbi.nlm.nih.gov/pubmed/ 19959485. Accessed November 2, 2011.
17. Ministério da Saüde. Programa de tratemento antiretroviral (TARV)-dados TARV nacionais. 2010. Available at: http://www.misau.gov.mz/pt/hiv- sida/dados-tarv-nacionais. Accessed January 31, 2012.
18. United Nations Development Programme. Mozambique National Human Development Report 2007. Maputo, Mozambique: United Nations Development Programme; 2007:59.
19. Lambdin B, Micek M, Koepsell T, et al. An assessment of the accuracy and availability of data in electronic patient tracking systems for patients receiving HIV treatment in central Mozambique. BMC Health Serv Res. 2012;12: 30. Available at:http://www.biomedcentral.com/1472-6963/12/30. Accessed November 2, 2011.
20. Lambdin BH, Micek MA, Koepsell TD, et al. Patient volume, human resource levels, and attrition from HIV treatment programs in central Mozambique. J Acquir Immune Defic Syndr. 2011;57:e33-e39. Available at: http://www.ncbi.nlm. nih.gov/pubmed/21372723. Accessed January 31, 2012.
21. Guo Y, Manatunga AK. Nonparametric estimation of the concordance correlation coefficient under univariate censoring. Biometrics. 2007;63: 164-172. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17447941. Accessed January 31, 2012.
22. van Buuren S, Boshuizen HC, Knook DL. Multiple imputation of missing blood pressure covariates in survival analysis. Stat Med. 1999;18: 681-694. Available at: http://www.ncbi.nlm.nih.gov/pubmed/10204197. Accessed January 31, 2012.
23. Rubin DB. Multiple Imputation for Non-Response in Surveys. New York, NY: John Wiley & Sons; 1987.
24. Lahuerta M, Lima J, Elul B, et al. Patients enrolled in HIV care in Mozambique: baseline characteristics and follow-up outcomes. J Acquir Immune Defic Syndr. 2011;58:e75-e86. Available at: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=3422887&tool=pmcentrez&rendertype=abstract. Accessed October 17, 2012.
25. Fox MP, Rosen S. Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007-2009: systematic review. Trop Med Int Health. 2010;15(suppl 1):1-15. Available at: http://www. pubmedcentral.nih.gov/articlerender.fcgi?artid=2948795&tool= pmcentrez&rendertype=abstract. Accessed October 17, 2012.
26. Micek MA, Gimbel-Sherr K, Baptista AJ, et al. Loss to follow-up of adults in public HIV care systems in central Mozambique: identifying obstacles to treatment. J Acquir Immune Defic Syndr. 2009;52:397-405. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2784145&tool= pmcentrez&rendertype=abstract. Accessed August 9, 2011.
27. Sherr KH, Micek MA, Gimbel SO, et al. Quality of HIV care provided by non-physician clinicians and physicians in Mozambique: a retrospective cohort study. AIDS. 2010;24(suppl 1):S59-S66. Available at: http://www.ncbi.nlm.nih. gov/pubmed/20023441. Accessed November 18, 2011.
28. Lara J, Lambdin BH. Exploratory analysis of the facility-level factors associated with HAART abandonment in central Mozambique. Presented at: APHA; November 11, 2009; Philadelphia, PA.