ExpresPlastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway

International Journal of Molecular Medicine

Volumn 31, Issue 6, 2013, Pages 1418-1428

  Qian, Xinhua ^a   Chen, Jia ^a   Zhao, Danhua ^a   Guo, Lishan ^a   Qian, Xinlai ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

globin gene; Epigenetic modifications; Fetal hemoglobin; P38 mitogen activated protein kinase; Plastrum testudinis

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BENZIDINE; CHINESE DRUG; HEMOGLOBIN F; HISTONE H3; HISTONE H4; MITOGEN ACTIVATED PROTEIN KINASE P38; PLASTRUM TESTUDINIS; TRYPAN BLUE; UNCLASSIFIED DRUG; HEMOGLOBIN GAMMA CHAIN; HERBACEOUS AGENT; HISTONE;

ARTICLE; BETA THALASSEMIA; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; EPIGENETICS; ERYTHROID PRECURSOR CELL; GAMMA GLOBIN GENE; GENE; GENE EXPRESSION; HEMOGLOBIN SYNTHESIS; HISTONE MODIFICATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIQUID CULTURE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CELL STRAIN K 562; CYTOLOGY; DRUG EFFECT; ERYTHROID CELL; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; TUMOR CELL LINE;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; EPIGENESIS, GENETIC; ERYTHROID CELLS; FETAL HEMOGLOBIN; GAMMA-GLOBINS; GENE EXPRESSION REGULATION; HISTONES; HUMANS; K562 CELLS; MAP KINASE SIGNALING SYSTEM; PROMOTER REGIONS, GENETIC;

EID: 84876391629     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1338     Document Type: Article

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