메뉴 건너뛰기




Volumn 8, Issue 4, 2013, Pages

Negative Association between Testosterone Concentration and Inflammatory Markers in Young Men: A Nested Cross-Sectional Study

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; ESTRADIOL; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; INTERFERON GAMMA INDUCED PROTEIN 10; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 7; INTERLEUKIN 8; INTERLEUKIN 9; LUTEINIZING HORMONE; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1 ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1 BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84876326351     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061466     Document Type: Article
Times cited : (147)

References (29)
  • 1
    • 0028175550 scopus 로고
    • The association of hypotestosteronemia with coronary artery disease in men
    • Phillips GB, Pinkernell BH, Jing TY, (1994) The association of hypotestosteronemia with coronary artery disease in men. Arterioscler Thromb 14: 701-706.
    • (1994) Arterioscler Thromb , vol.14 , pp. 701-706
    • Phillips, G.B.1    Pinkernell, B.H.2    Jing, T.Y.3
  • 2
    • 0034106347 scopus 로고    scopus 로고
    • Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study
    • Stellato RK, Feldman HA, Hamdy O, Horton ES, McKinlay JB, (2000) Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study. Diabetes Care 23: 490-494.
    • (2000) Diabetes Care , vol.23 , pp. 490-494
    • Stellato, R.K.1    Feldman, H.A.2    Hamdy, O.3    Horton, E.S.4    McKinlay, J.B.5
  • 3
    • 0027131198 scopus 로고
    • Relationship of sex hormones to lipids and lipoproteins in nondiabetic men
    • Haffner SM, Mykkanen L, Valdez RA, Katz MS, (1993) Relationship of sex hormones to lipids and lipoproteins in nondiabetic men. J Clin Endocrinol Metab 77: 1610-1615.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1610-1615
    • Haffner, S.M.1    Mykkanen, L.2    Valdez, R.A.3    Katz, M.S.4
  • 4
    • 2342644814 scopus 로고    scopus 로고
    • Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men
    • Laaksonen DE, Niskanen L, Punnonen K, Nyyssonen K, Tuomainen TP, et al. (2004) Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diabetes Care 27: 1036-1041.
    • (2004) Diabetes Care , vol.27 , pp. 1036-1041
    • Laaksonen, D.E.1    Niskanen, L.2    Punnonen, K.3    Nyyssonen, K.4    Tuomainen, T.P.5
  • 5
    • 0037652287 scopus 로고    scopus 로고
    • Inflammation, the metabolic syndrome and cardiovascular risk
    • Tracy RP (2003) Inflammation, the metabolic syndrome and cardiovascular risk. Int J Clin Pract Suppl: 10-17.
    • (2003) Int J Clin Pract Suppl , pp. 10-17
    • Tracy, R.P.1
  • 6
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
    • Rotter V, Nagaev I, Smith U, (2003) Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278: 45777-45784.
    • (2003) J Biol Chem , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 7
    • 0020972414 scopus 로고
    • Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis
    • Brown MS, Goldstein JL, (1983) Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu Rev Biochem 52: 223-261.
    • (1983) Annu Rev Biochem , vol.52 , pp. 223-261
    • Brown, M.S.1    Goldstein, J.L.2
  • 8
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R, (1999) Atherosclerosis-an inflammatory disease. N Engl J Med 340: 115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 9
    • 0036342660 scopus 로고    scopus 로고
    • Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study
    • Hak AE, Witteman JC, de Jong FH, Geerlings MI, Hofman A, et al. (2002) Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab 87: 3632-3639.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3632-3639
    • Hak, A.E.1    Witteman, J.C.2    de Jong, F.H.3    Geerlings, M.I.4    Hofman, A.5
  • 10
    • 2442422178 scopus 로고    scopus 로고
    • Endogenous sex hormones and progression of carotid atherosclerosis in elderly men
    • Muller M, van den Beld AW, Bots ML, Grobbee DE, Lamberts SW, et al. (2004) Endogenous sex hormones and progression of carotid atherosclerosis in elderly men. Circulation 109: 2074-2079.
    • (2004) Circulation , vol.109 , pp. 2074-2079
    • Muller, M.1    van den Beld, A.W.2    Bots, M.L.3    Grobbee, D.E.4    Lamberts, S.W.5
  • 11
    • 33847409722 scopus 로고    scopus 로고
    • Low testosterone levels are associated with coronary artery disease in male patients with angina
    • Rosano GM, Sheiban I, Massaro R, Pagnotta P, Marazzi G, et al. (2007) Low testosterone levels are associated with coronary artery disease in male patients with angina. Int J Impot Res 19: 176-182.
    • (2007) Int J Impot Res , vol.19 , pp. 176-182
    • Rosano, G.M.1    Sheiban, I.2    Massaro, R.3    Pagnotta, P.4    Marazzi, G.5
  • 12
    • 79955906626 scopus 로고    scopus 로고
    • Endogenous testosterone and cardiovascular disease in healthy men: a meta-analysis
    • Ruige JB, Mahmoud AM, De Bacquer D, Kaufman JM, (2011) Endogenous testosterone and cardiovascular disease in healthy men: a meta-analysis. Heart 97: 870-875.
    • (2011) Heart , vol.97 , pp. 870-875
    • Ruige, J.B.1    Mahmoud, A.M.2    De Bacquer, D.3    Kaufman, J.M.4
  • 13
    • 70549086629 scopus 로고    scopus 로고
    • The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process
    • Jones TH, Saad F, (2009) The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process. Atherosclerosis 207: 318-327.
    • (2009) Atherosclerosis , vol.207 , pp. 318-327
    • Jones, T.H.1    Saad, F.2
  • 15
    • 0027299544 scopus 로고
    • Effect of gonadal steroids on the production of IL-1 and IL-6 by blood mononuclear cells in vitro
    • Li ZG, Danis VA, Brooks PM, (1993) Effect of gonadal steroids on the production of IL-1 and IL-6 by blood mononuclear cells in vitro. Clin Exp Rheumatol 11: 157-162.
    • (1993) Clin Exp Rheumatol , vol.11 , pp. 157-162
    • Li, Z.G.1    Danis, V.A.2    Brooks, P.M.3
  • 16
    • 0035881678 scopus 로고    scopus 로고
    • Testosterone acts directly on CD4+ T lymphocytes to increase IL-10 production
    • Liva SM, Voskuhl RR, (2001) Testosterone acts directly on CD4+ T lymphocytes to increase IL-10 production. J Immunol 167: 2060-2067.
    • (2001) J Immunol , vol.167 , pp. 2060-2067
    • Liva, S.M.1    Voskuhl, R.R.2
  • 17
    • 3242667701 scopus 로고    scopus 로고
    • The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men
    • Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS, et al. (2004) The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab 89: 3313-3318.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3313-3318
    • Malkin, C.J.1    Pugh, P.J.2    Jones, R.D.3    Kapoor, D.4    Channer, K.S.5
  • 18
    • 78449294931 scopus 로고    scopus 로고
    • Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study
    • Kalinchenko SY, Tishova YA, Mskhalaya GJ, Gooren LJ, Giltay EJ, et al. (2010) Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study. Clin Endocrinol (Oxf) 73: 602-612.
    • (2010) Clin Endocrinol (Oxf) , vol.73 , pp. 602-612
    • Kalinchenko, S.Y.1    Tishova, Y.A.2    Mskhalaya, G.J.3    Gooren, L.J.4    Giltay, E.J.5
  • 20
    • 0033305020 scopus 로고    scopus 로고
    • A critical evaluation of simple methods for the estimation of free testosterone in serum
    • Vermeulen A, Verdonck L, Kaufman JM, (1999) A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 84: 3666-3672.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3666-3672
    • Vermeulen, A.1    Verdonck, L.2    Kaufman, J.M.3
  • 21
    • 68649091506 scopus 로고    scopus 로고
    • The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
    • Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, et al. (2009) The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 31: 220-231.
    • (2009) Immunity , vol.31 , pp. 220-231
    • Androulidaki, A.1    Iliopoulos, D.2    Arranz, A.3    Doxaki, C.4    Schworer, S.5
  • 22
    • 35948930594 scopus 로고    scopus 로고
    • Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism
    • Yialamas MA, Dwyer AA, Hanley E, Lee H, Pitteloud N, et al. (2007) Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab 92: 4254-4259.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4254-4259
    • Yialamas, M.A.1    Dwyer, A.A.2    Hanley, E.3    Lee, H.4    Pitteloud, N.5
  • 24
    • 0036280935 scopus 로고    scopus 로고
    • Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men
    • Khosla S, Atkinson EJ, Dunstan CR, O'Fallon WM, (2002) Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men. J Clin Endocrinol Metab 87: 1550-1554.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1550-1554
    • Khosla, S.1    Atkinson, E.J.2    Dunstan, C.R.3    O'Fallon, W.M.4
  • 25
    • 30344449759 scopus 로고    scopus 로고
    • Correlation between testosterone and the inflammatory marker soluble interleukin-6 receptor in older men
    • Maggio M, Basaria S, Ble A, Lauretani F, Bandinelli S, et al. (2006) Correlation between testosterone and the inflammatory marker soluble interleukin-6 receptor in older men. J Clin Endocrinol Metab 91: 345-347.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 345-347
    • Maggio, M.1    Basaria, S.2    Ble, A.3    Lauretani, F.4    Bandinelli, S.5
  • 26
    • 84863558850 scopus 로고    scopus 로고
    • Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men
    • Ruige JB, Bekaert M, Lapauw B, Fiers T, Lehr S, et al. (2012) Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men. J Clin Endocrinol Metab 97: E1187-1191.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Ruige, J.B.1    Bekaert, M.2    Lapauw, B.3    Fiers, T.4    Lehr, S.5
  • 27
    • 84893738314 scopus 로고    scopus 로고
    • Association between testosterone levels and risk of future rheumatoid arthritis in men - a population based case-control study
    • In press
    • Pikwer M, Giwercman A, Bergström U, Nilsson J, Jacobsson L, et al. (2013) Association between testosterone levels and risk of future rheumatoid arthritis in men - a population based case-control study. Ann Rheum Dis. In press.
    • (2013) Ann Rheum Dis
    • Pikwer, M.1    Giwercman, A.2    Bergström, U.3    Nilsson, J.4    Jacobsson, L.5
  • 28
    • 0029968711 scopus 로고    scopus 로고
    • Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males
    • Vermeulen A, Kaufman JM, Giagulli VA, (1996) Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males. J Clin Endocrinol Metab 81: 1821-1826.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1821-1826
    • Vermeulen, A.1    Kaufman, J.M.2    Giagulli, V.A.3
  • 29
    • 84873475820 scopus 로고    scopus 로고
    • Emerging biomarkers and intervention targets for immune-modulation of atherosclerosis - A review of the experimental evidence
    • Bjorkbacka H, Fredrikson GN, Nilsson J, (2012) Emerging biomarkers and intervention targets for immune-modulation of atherosclerosis- A review of the experimental evidence. Atherosclerosis 227(1): 9-17.
    • (2012) Atherosclerosis , vol.227 , Issue.1 , pp. 9-17
    • Bjorkbacka, H.1    Fredrikson, G.N.2    Nilsson, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.