Naltrexone reduction of long-term smoking cessation weight gain in women but not men: A randomized controlled trial

Biological Psychiatry

Volumn 73, Issue 9, 2013, Pages 924-930

  King, Andrea C ^a   Cao, Dingcai ^b   Zhang, Lingjiao ^a   O'Malley, Stephanie S ^c  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Naltrexone; nicotine dependence; opioid antagonist; sex differences; smoking cessation; weight gain

Indexed keywords

NALTREXONE; NICOTINE; NICOTINE PATCH; PLACEBO;

ADULT; ARTICLE; BODY MASS; COUNSELING; DRUG DOSE COMPARISON; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SIDE EFFECT; SMOKING CESSATION; TOBACCO DEPENDENCE; WEIGHT GAIN;

ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; NALTREXONE; SEX FACTORS; SMOKING CESSATION; TREATMENT OUTCOME; WEIGHT GAIN;

EID: 84876297943     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.09.025     Document Type: Article

References (50)

1. Centers for Disease Control and Prevention (CDC) NCfHSN National Health and Nutrition Examination Survey Data 2011 US Department of Health and Human Services, Centers for Disease Control and Prevention Hyattsville, MD
2. A.H. Mokdad, J.S. Marks, D.F. Stroup, and J.L. Gerberding Actual causes of death in the United States, 2000 JAMA 291 2004 1238 1245
3. US Department of Health and Human Services Health People 2000 1990 US Government Printing Office Washington, DC
4. A.C. Farley, P. Hajek, D. Lycett, and P. Aveyard Interventions for preventing weight gain after smoking cessation Cochrane Database Syst Rev 1 2012 CD006219
5. D.F. Williamson, J. Madans, R.F. Anda, J.C. Kleinman, G.A. Giovino, and T. Byers Smoking cessation and severity of weight gain in a national cohort N Engl J Med 324 1991 739 745
6. L.A. Sanchez-Johnsen, M.R. Carpentier, and A.C. King Race and sex associations to weight concerns among urban African American and Caucasian smokers Addict Behav 36 2011 14 17
7. J.S. Mizes, D.M. Sloan, K. Segraves, B. Spring, R. Pingitore, and J. Kristeller The influence of weight-related variables on smoking cessation Behav Ther 29 1998 371 385
8. A. King, H. de Wit, R.C. Riley, D. Cao, R. Niaura, and D. Hatsukami Efficacy of naltrexone in smoking cessation: a preliminary study and an examination of sex differences Nicotine Tob Res 8 2006 671 682
9. A.C. King, D. Cao, S.S. O'Malley, H.R. Kranzler, X. Cai, and H. de Wit Effects of naltrexone on smoking cessation outcomes and weight gain in nicotine-dependent men and women J Clin Psychopharm 32 2012 630 636
10. S. Krishnan-Sarin, B. Meandzija, and S. O'Malley Naltrexone and nicotine patch smoking cessation: A preliminary study Nicotine Tob Res 5 2003 851 857
11. S.S. O'Malley, J.L. Cooney, S. Krishnan-Sarin, J.A. Dubin, S.A. McKee, and N.L. Cooney A controlled trial of naltrexone augmentation of nicotine replacement therapy for smoking cessation Arch Intern Med 166 2006 667 674
12. C.N. Epperson, B. Toll, R. Wu, Z. Amin, K.A. Czarkowski, and P. Jatlow Exploring the impact of gender and reproductive status on outcomes in a randomized clinical trial of naltrexone augmentation of nicotine patch Drug Alcohol Depend 112 2010 1 8
13. B.A. Toll, M. White, R. Wu, B. Meandzija, P. Jatlow, and R. Makuch Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: A randomized trial Drug Alcohol Depend 111 2010 200 206
14. E.M. Weerts, Y.K. Kim, G.S. Wand, R.F. Dannals, J.S. Lee, and J.J. Frost Differences in delta- and mu-opioid receptor blockade measured by positron emission tomography in naltrexone-treated recently abstinent alcohol-dependent subjects Neuropsychopharmacology 33 2008 653 665
15. C. Lerman, W. Berrettini, A. Pinto, F. Patterson, S. Crystal-Mansour, and E.P. Wileyto Changes in food reward following smoking cessation: A pharmacogenetic investigation Psychopharmacology (Berl) 174 2004 571 577
16. S.M. Hall, R. McGee, C. Tunstall, J. Duffy, and N. Benowitz Changes in food intake and activity after quitting smoking J Consult Clin Psychol 57 1989 81 86
17. K.A. Perkins, L.H. Epstein, B.L. Marks, R.L. Stiller, and R.G. Jacob The effect of nicotine on energy expenditure during light physical activity N Engl J Med 320 1989 898 903
18. M.R. Yeomans, and R.W. Gray Selective effects of naltrexone on food pleasantness and intake Physiol Behav 60 1996 439 446
19. M.R. Yeomans, and R.W. Gray Effects of naltrexone on food intake and changes in subjective appetite during eating: evidence for opioid involvement in the appetizer effect Physiol Behav 62 1997 15 21
20. A. Drewnowski Metabolic determinants of binge eating Addict Behav 20 1995 733 745
21. P.J. Kenny Common cellular and molecular mechanisms in obesity and drug addiction Nat Rev Neurosci 12 2011 638 651
22. K.C. Berridge, C.Y. Ho, J.M. Richard, and A.G. DiFeliceantonio The tempted brain eats: Pleasure and desire circuits in obesity and eating disorders Brain Res 1350 2010 43 64
23. M.C. Fiore, C.R. Jaén, T.B. Baker, W.C. Bailey, N.L. Benowitz, and S.J. Curry Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline 2008 US Department of Health and Human Services Public Health Service Rockville, MD
24. G.S. Sachs, and C. Guille Weight gain associated with use of psychotropic medications J Clin Psychiatry 60 suppl 21 1999 16 19
25. D.E. Casey, D.W. Haupt, J.W. Newcomer, D.C. Henderson, M.J. Sernyak, and M. Davidson Antipsychotic-induced weight gain and metabolic abnormalities: Implications for increased mortality in patients with schizophrenia J Clin Psychiatry 65 suppl 7 2004 4 18 quiz 19-20
26. L. Citrome Quantifying risk: The role of absolute and relative measures in interpreting risk of adverse reactions from product labels of antipsychotic medications Curr Drug Saf 4 2009 229 237
27. A.C. King, D. Cao, C.C. Southard, and A. Matthews Racial differences in eligibility and enrollment in a smoking cessation clinical trial Health Psychol 30 2011 40 48
28. L.C. Sobell, and M.B. Sobell Alcohol Timeline Follow-Back Users' Manual 1995 Addiction Research Foundation Toronto, Ontario, Canada
29. (2000): Obesity: Preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 894:i-xii, 1-253.
30. C.S. Pomerleau, A.N. Zucker, and A.J. Stewart Characterizing concerns about post-cessation weight gain: Results from a national survey of women smokers Nicotine Tob Res 3 2001 51 60
31. N.M. Avena, P. Rada, and B.G. Hoebel Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake Neurosci Biobehav Rev 32 2008 20 39
32. K.J. Wong, F.H. Wojnicki, and R.L. Corwin Baclofen, raclopride, and naltrexone differentially affect intake of fat/sucrose mixtures under limited access conditions Pharmacol Biochem Behav 92 2009 528 536
33. S. Pecina, and K.S. Smith Hedonic and motivational roles of opioids in food reward: Implications for overeating disorders Pharmacol Biochem Behav 97 2010 34 46
34. M. Hudson, E. Rahme, H. Behlouli, R. Sheppard, and L. Pilote Sex differences in the effectiveness of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in patients with congestive heart failure - a population study Eur J Heart Fail 9 2007 602 609
35. J.I. Macdiarmid, A. Vail, J.E. Cade, and J.E. Blundell The sugar-fat relationship revisited: Differences in consumption between men and women of varying BMI Int J Obes Relat Metab Disord 22 1998 1053 1061
36. W.M. Hopman, C. Leroux, C. Berger, L. Joseph, S.I. Barr, and J.C. Prior Changes in body mass index in Canadians over a five-year period: Results of a prospective, population-based study BMC Public Health 7 2007 150
37. M.N. Potenza, K.I. Hong, C.M. Lacadie, R.K. Fulbright, K.L. Tuit, and R. Sinha Neural correlates of stress-induced and cue-induced drug craving: Influences of sex and cocaine dependence Am J Psychiatry 169 2012 406 414
38. E.C. Donny, A.R. Caggiula, M.T. Weaver, M.E. Levin, and A.F. Sved The reinforcement-enhancing effects of nicotine: Implications for the relationship between smoking, eating and weight Physiol Behav 104 2011 143 148
39. P.J. Kenny Reward mechanisms in obesity: New insights and future directions Neuron 69 2011 664 679
40. S.J. Torres, and C.A. Nowson Relationship between stress, eating behavior, and obesity Nutrition 23 2007 887 894
41. T.C. Adam, and E.S. Epel Stress, eating and the reward system Physiology Behavior 91 2007 449 458
42. D.J. Roche, E. Childs, A.M. Epstein, and A.C. King Acute HPA axis response to naltrexone differs in female vs. male smokers Psychoneuroendocrinology 35 2010 596 606
43. A.J. Chamorro, M. Marcos, J.A. Miron-Canelo, I. Pastor, R. Gonzalez-Sarmiento, and F.J. Laso Association of micro-opioid receptor (OPRM1) gene polymorphism with response to naltrexone in alcohol dependence: A systematic review and meta-analysis Addict Biol 17 2012 505 512
44. Z. Walsh, A. Epstein, G. Munisamy, and A. King The impact of depressive symptoms on the efficacy of naltrexone in smoking cessation J Addict Dis 27 2008 65 72
45. A. King, D. Cao, C. Vanier, and T. Wilcox Naltrexone decreases heavy drinking rates in smoking cessation treatment: an exploratory study Alcohol Clin Exp Res 33 2009 1044 1050
46. S.S. O'Malley, S. Krishnan-Sarin, S.A. McKee, R.F. Leeman, N.L. Cooney, and B. Meandzija Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation Int J Neuropsychopharmacol 12 2009 589 597
47. Fucito LM, Park A, Gulliver SB, Mattson ME, Gueorguieva RV, O'Malley SS (2012): Cigarette smoking predicts differential benefit from naltrexone for alcohol dependence [published online ahead of print April 25]. Biol Psychiatry.
48. S.T. Stewart, D.M. Cutler, and A.B. Rosen Forecasting the effects of obesity and smoking on U.S. life expectancy N Engl J Med 361 2009 2252 2260
49. A. Chiolero, D. Faeh, F. Paccaud, and J. Cornuz Consequences of smoking for body weight, body fat distribution, and insulin resistance Am J Clin Nutr 87 2008 801 809
50. NHLBI Expert Panel on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults (1998): Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. Obes Res 6(suppl 2):51S-209S.