Lymph node transfer and perinodal lymphatic growth factor treatment for lymphedema

Annals of Surgery

Volumn 257, Issue 5, 2013, Pages 961-967

  Honkonen, Krista M ^a   Visuri, Mikko T ^b   Tervala, Tomi V ^b   Halonen, Paavo J ^a   Koivisto, Mari ^c   Lähteenvuo, Markku T ^a   Alitalo, Kari K ^d   Ylä Herttuala, Seppo ^a   Saaristo, Anne M ^b,c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

adenovirus; growth factor; lymph node transfer; lymphangiogenesis; lymphedema; VEGF C

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CEFUROXIME; SODIUM CHLORIDE; VASCULOTROPIN C;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENETIC CODE; HEMATOLOGICAL PROCEDURE; INGUINAL LYMPH NODE; LYMPH NODE TRANSFER; LYMPHANGIOGENESIS; LYMPHEDEMA; MACROPHAGE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; TRANSPLANTATION; VASCULARIZATION;

ADENOVIRIDAE; ANIMALS; COMBINED MODALITY THERAPY; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; GUIDED TISSUE REGENERATION; INJECTIONS, INTRALYMPHATIC; LINEAR MODELS; LYMPH NODES; LYMPHANGIOGENESIS; LYMPHEDEMA; SUS SCROFA; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

EID: 84876297899     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e31826ed043     Document Type: Article

References (30)

1. Alitalo K. The lymphatic vasculature in disease. Nat Med. 2011;17:1371-1380.
2. Witte MH, Witte CL. Lymphatics and blood vessels, lymphangiogenesis and hemangiogenesis: from cell biology to clinical medicine. Lymphology. 1987;20:257-266.
3. Damstra RJ, Voesten HG, Klinkert P, et al. Circumferential suction-assisted lipectomy for lymphoedema after surgery for breast cancer. Br J Surg. 2009;96:859-864.
4. Baumeister RG, Seifert J, Hahn D. Autotransplantation of lymphatic vessels. Lancet. 1981;1:147.
5. Nagase T, Gonda K, Inoue K, et al. Treatment of lymphedema with lymphati-covenular anastomoses. Int J Clin Oncol. 2005;10:304-310.
6. Suami H, Chang DW. Overview of surgical treatments for breast cancer-related lymphedema. Plast Reconstr Surg. 2010;126:1853-1863.
7. Felmerer G, Sattler T, Lohrmann C, et al. Treatment of various secondary lymphedemas by microsurgical lymph vessel transplantation. Microsurgery. 2012;32:171-177.
8. Becker C, Assouad J, Riquet M, et al. Postmastectomy lymphedema: longterm results following microsurgical lymph node transplantation. Ann Surg. 2006;243:313-315.
9. Rabson JA, Geyer SJ, Levine G, et al. Tumor immunity in rat lymph nodes following transplantation. Ann Surg. 1982;196:92-99.
10. Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol. 2000;18:767-811.
11. Saaristo A, Niemi T, Viitanen T, et al. Microvascular breast reconstruction and lymph node transfer for postmastectomy lymphedema patients. Ann Surg. 2012;255:468-473.
12. Lähteenvuo M, Honkonen K, Tervala T, et al. Growth factor therapy and autologous lymph node transfer in lymphedema. Circulation. 2011;123: 613-620.
13. Hadamitzky C, Blum KS, Pabst R. Regeneration of autotransplanted avascu-lar lymph nodes in the rat is improved by platelet-rich plasma. J Vasc Res. 2009;46:389-396.
14. Tammela T, Saaristo A, Holopainen T, et al. Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation. Nat Med. 2007;13:1458-1466.
15. Mebius RE, Streeter PR, Breve J, et al. The influence of afferent lymphatic vessel interruption on vascular addressin expression. J Cell Biol. 1991;115: 85-95.
16. Baker A, Kim H, Semple JL, et al. Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy. Breast Cancer Res. 2010;12:R70.
17. Szuba A, Skobe M, Kärkkäinen MJ, et al. Therapeutic lymphangiogenesis with human recombinant VEGF-C. FASEBJ. 2002;16:1985-1987.
18. Kärkkäinen MJ, Saaristo A, Jussila L, et al. A model for gene therapy of human hereditary lymphedema. Proc Natl Acad Sci U S A. 2001;98: 12677-12682.
19. Veikkola T, Jussila L, Mäkinen T, et al. Signaling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J. 2001;20:1223-1231.
20. Crystal RG, Harvey BG, Wisnivesky JP, et al. Analysis of risk factors for local delivery of low-and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions. Hum Gene Ther. 2002;13:65-100.
21. Hedman M, Hartikainen J, Syvänne M, et al. Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT). Circulation. 2003;107:2677-2683.
22. Rajagopalan S, Mohler ER, III, Lederman RJ, et al. Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation. 2003;108:1933-1938.
23. Jussila L, Valtola R, Partanen TA, et al. Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3. Cancer Res. 1998;58:1599-1604.
24. Lin CH, Ali R, Chen SC, et al. Vascularized groin lymph node transfer using the wrist as a recipient site for management of postmastectomy upper extremity lymphedema. Plast Reconstr Surg. 2009;123:1265-1275.
25. O'Brien BM, Das SK, Franklin JD, et al. Effect of lymphangiography on lymphedema. Plast Reconstr Surg. 1981;68:922-926.
26. Steckel RJ, Cameron TP. Changes in lymph node size induced by lymphan-giography. Radiology. 1966;87:753-755.
27. Schnell MA, Zhang Y, Tazelaar J, et al. Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. Mol Ther. 2001;3:708-722.
28. Simon RH, Engelhardt JF, Yang Y, et al. Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study. Hum Gene Ther. 1993;4:771-780.
29. Holopainen T, Bry M, Alitalo K, et al. Perspectives on lymphangiogenesis and angiogenesis in cancer. J Surg Oncol. 2011;103:484-488.
30. Mantovani A, Romero P, Palucka AK, et al. Tumour immunity: effector response to tumour and role of the microenvironment. Lancet. 2008;371: 771-783.