Early thromboelastometric variables reliably predict maximum clot firmness in patients undergoing cardiac surgery: A step towards earlier decision making

Acta Anaesthesiologica Scandinavica

Volumn 57, Issue 5, 2013, Pages 594-603

  Dirkmann, D ^a   Gorlinger K ^a   Dusse, F ^a   Kottenberg, E ^a   Peters, J ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; HEPARIN; PROTAMINE;

ACTIN POLYMERIZATION; ARTICLE; BLOOD CLOTTING PARAMETERS; BLOOD CLOTTING TEST; BLOOD CLOTTING TIME; BLOOD EXAMINATION; CARDIOPULMONARY BYPASS; CLINICAL DECISION MAKING; CONTROLLED STUDY; CORRELATION COEFFICIENT; FIBRINOLYSIS; HUMAN; MAJOR CLINICAL STUDY; MAXIMUM CLOT FIRMNESS; MEASUREMENT ACCURACY; POINT OF CARE TESTING; PREDICTIVE VALUE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; THROMBOELASTOMETRY;

AREA UNDER CURVE; BLOOD COAGULATION; BLOOD COAGULATION DISORDERS; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; FIBRINOLYTIC AGENTS; HEPARIN; HEPARIN ANTAGONISTS; HUMANS; POINT-OF-CARE SYSTEMS; PROTAMINES; REPRODUCIBILITY OF RESULTS; ROC CURVE; SENSITIVITY AND SPECIFICITY; THROMBELASTOGRAPHY; TIME FACTORS;

EID: 84876296413     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.12040     Document Type: Article

References (30)

1. Stover EP, Siegel LC, Parks R, Levin J, Body SC, Maddi R, D'Ambra MN, Mangano DT, Spiess BD. Variability in transfusion practice for coronary artery bypass surgery persists despite national consensus guidelines: a 24-institution study. Institutions of the Multicenter Study of Perioperative Ischemia Research Group. Anesthesiology 1998; 88: 327-33.
2. Haas T, Spielmann N, Mauch J, Madjdpour C, Speer O, Schmugge M, Weiss M. Comparison of thromboelastometry (ROTEM®) with standard plasmatic coagulation testing in paediatric surgery. Br J Anaesth 2012; 108: 36-41.
3. Stanworth SJ, Grant-Casey J, Lowe D, Laffan M, New H, Murphy MF, Allard S. The use of fresh-frozen plasma in England: high levels of inappropriate use in adults and children. Transfusion 2011; 51: 62-70.
4. Shore-Lesserson L, Manspeizer HE, DePerio M, Francis S, Vela-Cantos F, Ergin MA. Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery. Anesth Analg 1999; 88: 312-9.
5. Ak K, Isbir CS, Tetik S, Atalan N, Tekeli A, Aljodi M, Civelik A, Arsan S. Thromboelastography-based transfusion algorithm reduces blood product use after elective CABG: a prospective randomized study. J Card Surg 2009; 24: 404-10.
6. Görlinger K, Dirkmann D, Hanke AA, Kamler M, Kotten-berg E, Thielmann M, Jakob H, Peters J. First line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allo-geneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. Anesthesiology 2011; 115: 1179-91.
7. Mittermayr M, Margreiter J, Velik-Salchner C, Klingler A, Streif W, Fries D, Innerhofer P. Effects of protamine and heparin can be detected and easily differentiated by modified thrombelastography (Rotem): an in vitro study. Br J Anaesth 2005; 95: 310-6.
8. Mittermayr M, Velik-Salchner C, Stalzer B, Margreiter J, Klingler A, Fries D, Innerhofer P. Detection of protamine and heparin after termination of cardiopulmonary bypass by thrombelastometry (ROTEM): results of a pilot study. Anesth Analg 2009; 108: 743-50.
9. Görlinger K, Jambor C, Hanke AA, Dirkmann D, Adamzik M, Hartmann M, Rahe-Meyer N. Perioperative coagulation management and control of platelet transfusion by point-of-care platelet function analysis. Transfus Med Hemother 2007; 34: 396-411.
10. Görlinger K, Dirkmann D, Weber CF, Rahe-Meyer N, Hanke A. Algorithms for transfusion and coagulation management in massive haemorrhage. Anästh Intensivmed 2011; 52: 145-59.
11. Hartert H. Thrombelastography, a method for physical analysis of blood coagulation. Z Gesamte Exp Med 1951; 117: 189-203.
12. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 327: 307-10.
13. Lang T, Bauters A, Braun SL, Pötzsch B, von Pape K-W, Kolde H-J, Lakner M. Multi-centre investigation on reference ranges for ROTEM thromboelastometry. Blood Coagul Fibrinolysis 2005; 16: 301-10.
14. Zou KH, O'Malley AJ, Mauri L. Receiver-operating characteristic analysis for evaluating diagnostic tests and predictive models. Circulation 2007; 115: 654-7.
15. Hilden J. The area under the ROC curve and its competitors. Med Decis Making 1991; 11: 95-101.
16. Ogawa S, Szlam F, Chen EP, Nishimura T, Kim H, Roback JD, Levy JH, Tanaka KA. A comparative evaluation of rotation thromboelastometry and standard coagulation tests in hemodilution-induced coagulation changes after cardiac surgery. Transfusion 2012; 52: 14-22.
17. Solomon C, Cadamuro J, Ziegler B, Schöchl H, Varvenne M, Sørensen B, Hochleitner G, Rahe-Meyer N. A comparison of fibrinogen measurement methods with fibrin clot elasticity assessed by thromboelastometry, before and after administration of fibrinogen concentrate in cardiac surgery patients. Transfusion 2011; 51: 1695-706.
18. Herbstreit F, Winter EM, Peters J, Hartmann M. Monitoring of haemostasis in liver transplantation: comparison of laboratory based and point of care tests. Anaesthesia 2010; 65: 44-9.
19. Schöchl H, Cotton B, Inaba K, Fischer H, Voelckel W, Solomon C. FIBTEM provides early prediction of massive transfusion in trauma. Crit Care 2011; 15: R265.
20. Karlsson M, Ternström L, Hyllner M, Baghaei F, Nilsson S, Jeppsson A. Plasma fibrinogen level, bleeding, and transfusion after on-pump coronary artery bypass grafting surgery: a prospective observational study. Transfusion 2008; 10: 2152-8.
21. Rahe-Meyer N, Pichlmaier M, Haverich A, Solomon C, Win-terhalter M, Piepenbrock S, Tanaka KA. Bleeding management with fibrinogen concentrate targeting a high-normal plasma fibrinogen level: a pilot study. Br JAnaesth 2009; 102: 785-92.
22. Rahe-Meyer N, Solomon C, Winterhalter M, Piepenbrock S, Tanaka KA, HaverichA, PichlmaierM.Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoab-dominal aortic aneurysm surgery. J Thorac Cardiovasc Surg 2009; 138: 694-702.
23. Solomon C, Pichlmaier U, Schoechl H, Hagl C, Raymonds K, Scheinichen D, Koppert W, Rahe-Meyer N. Recovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery. Br J Anaesth 2010; 104: 555-62.
24. Molinaro RJ, Szlam F, Levy JH, Fantz CR, Tanaka KA. Low plasma fibrinogen levels with the Clauss method during anticoagulation with bivalirudin. Anesthesiology 2008; 109: 160-1.
25. Sucker C, Zotz RB, Görlinger K, Hartmann M. Rotational thrombelastometry for the bedside monitoring of recom-binant hirudin. Acta Anaesthesiol Scand 2008; 52: 358-62.
26. Fenger-Eriksen C, Tønnesen E, J Ingerslev J, Sørensen B. Mechanisms of hydroxyethyl starch-induced dilutional coagulopathy. J Thromb Haemost 2009; 7: 1099-105.
27. Lang T, Johanning K, Metzler H, Piepenbrock S, Solomon C, Rahe-Meyer N, Tanaka KA. The effects of fibrinogen levels on thromboelastometric variables in the presence of throm-bocytopenia. Anesth Analg 2009; 108: 751-8.
28. Tanaka KA, Szlam F, Sun HY, Taketomi T, Levy JH. Thrombin generation assay and viscoelastic coagulation monitors demonstrate differences in the mode of thrombin inhibition between unfractionated heparin and bivalirudin. Anesth Analg 2007; 105: 933-9.
29. Toulon P, Ozier Y, Ankri A, Fléron M-H, Leroux G, Samama CM. Point-of-care versus central laboratory coagulation testing during haemorrhagic surgery. A multicenter study. Thromb Haemost 2009; 101: 394-401.
30. Venema LF, Post WJ, Hendriks HGD, Huet RCG, de Wolf JThW, deVries AJ.An assessmentof clinical interchangeabil-ity ofTEG® and RoTEM® thromboelastographic variables in cardiac surgical patients. Anesth Analg 2010; 111: 339-44.