Optimization of microwave-Assisted extraction of analgesic and anti-inflammatory drugs from human plasma and urine using response surface experimental designs †

Journal of Separation Science

Volumn 36, Issue 8, 2013, Pages 1446-1454

  Fernández, Purificación ^a   Fernández, Ana M ^b   Bermejo, Ana M ^a   Lorenzo, Rosa A ^c   Carro, Antonia M ^c  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Drug Addiction Assistance Unit   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Analgesics; Experimental design; Human biological matrices; Liquid chromatography; Microwave Assisted extraction

Indexed keywords

ANALGESICS; ANTI-INFLAMMATORY DRUGS; BIOLOGICAL MATRIXES; DESIRABILITY FUNCTION; EXTRACTION OPTIMIZATIONS; EXTRACTION TECHNIQUES; MICROWAVE-ASSISTED EXTRACTION; PHOTODIODE ARRAY DETECTIONS;

BODY FLUIDS; DESIGN OF EXPERIMENTS; LIQUID CHROMATOGRAPHY; OPTIMIZATION; PLASMAS; STATISTICS;

SOLVENT EXTRACTION;

ACETIC ACID ETHYL ESTER; DICHLOROMETHANE; DICLOFENAC; DIPYRONE; IBUPROFEN; PARACETAMOL; TRAMADOL;

ARTICLE; BLOOD SAMPLING; DRUG ISOLATION; EXPERIMENTAL DESIGN; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH TEMPERATURE; HUMAN; LIMIT OF DETECTION; LIQUID PHASE MICROEXTRACTION; MICROWAVE ASSISTED EXTRACTION; MICROWAVE OVEN; MICROWAVE RADIATION; PLASMA; PRIORITY JOURNAL; REPRODUCIBILITY; SOLVENT EFFECT; SOLVENT EXTRACTION; URINALYSIS; URINE;

ANALGESICS; ANTI-INFLAMMATORY AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MICROWAVES; SPECTROPHOTOMETRY, ULTRAVIOLET; SURFACE PROPERTIES;

EID: 84876294973     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201201105     Document Type: Article

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