Thresholds and perception of cold pain, heat pain, and the thermal grill illusion in patients with major depressive disorder

Psychosomatic Medicine

Volumn 75, Issue 3, 2013, Pages 281-287

  Boettger, Michael Karl ^a,c,d   Grossmann, David ^b   Bär, Karl Jürgen ^b  

^a Institute of Physiology i   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

^c BAYER PHARMA AG   (Germany)

^d UNIVERSITY OF WUPPERTAL   (Germany)

Author keywords

cold pain; depression; heat pain; pain threshold; thermal grill illusion

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COLD PAIN THRESHOLD; CONTROLLED STUDY; FEMALE; HEAT PAIN THRESHOLD; HUMAN; ILLUSION; MAJOR DEPRESSION; MALE; NOCICEPTION; PAIN THRESHOLD; PRIORITY JOURNAL; SENSATION; STIMULUS RESPONSE; TEMPERATURE; THERMAL GRILL ILLUSION;

ADULT; ANALYSIS OF VARIANCE; COLD TEMPERATURE; DEPRESSIVE DISORDER, MAJOR; FEMALE; HOT TEMPERATURE; HUMANS; ILLUSIONS; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; PAIN PERCEPTION; PAIN THRESHOLD; THERMOSENSING; YOUNG ADULT;

EID: 84876290989     PISSN: 00333174     EISSN: 15347796     Source Type: Journal    
DOI: 10.1097/PSY.0b013e3182881a9c     Document Type: Article

References (37)

1. Thunberg T. Förnimmelserna vid till samma ställe lokasirerad, samtidigtb pagaende köld och värmeretning. Uppsala Lakkforen Fohr 1896:489-95.
2. Craig AD, Bushnell MC. The thermal grill illusion: unmasking the burn of cold pain. Science 1994;265:252-5.
3. Craig AD. Can the basis for central neuropathic pain be identified by using a thermal grill? Pain 2008;135:215-6.
4. Bär KJ, Brehm S, Boettger MK, Boettger S, Wagner G, Sauer H. Pain perception in major depression depends on pain modality. Pain 2005;117:97-103.
5. Lautenbacher S, Spernal J, Schreiber W, Krieg JC. Relationship between clinical pain complaints and pain sensitivity in patients with depression and panic disorder. Psychosom Med 1999;61:822-7.
6. Bär KJ, Terhaar J, Boettger MK, Boettger S, Berger S, Weiss T. Pseudohypoalgesia on the skin: a novel view on the paradox of pain perception in depression. J Clin Psychopharmacol 2011;31:103-7.
7. Corruble E, Guelfi JD. Pain complaints in depressed inpatients. Psycho-pathology 2000;33:307-9.
8. Boettger MK, Schwier C, Bär KJ. Sad mood increases pain sensitivity upon thermal grill illusion stimulation: implications for central pain processing. Pain 2011;152:123-30.
9. Pinerua-Shuhaibar L, Villalobos N, Delgado N, Rubio MA, Suarez-Roca H. Enhanced central thermal nociception in mildly depressed nonpatients and transiently sad healthy subjects. J Pain 2011;12:360-9.
10. Lindstedt F, Lonsdorf TB, Schalling M, Kosek E, Ingvar M. Perception of thermal pain and the thermal grill illusion is associated with polymorphisms in the serotonin transporter gene. PLoS One 2011;6:e17752.
11. Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010;167:509-27.
12. Karg K, Burmeister M, Shedden K, Sen S. The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry 2011;68:444-54.
13. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971;9:97-113.
14. First MB. Clinical utility: a prerequisite for the adoption of a dimensional approach in DSM. J Abnorm Psychol 2005;114:560-4.
15. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62.
16. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561-71.
17. Schwier C, Kliem A, Boettger MK, Bär KJ. Increased cold-pain thresholds in major depression. J Pain 2010;11:287-90.
18. Bouhassira D, Kern D, Rouaud J, Pelle-Lancien E, Morain F. Investigation of the paradoxical painful sensation ('illusion of pain') produced by a thermal grill. Pain 2005;114:160-7.
19. Boettger MK, Greiner W, Rachow T, Bruhl C, Bar KJ. Sympathetic skin response following painful electrical stimulation is increased in major depression. Pain 2010;149:130-4.
20. Terhaar J, Boettger MK, Schwier C, Wagner G, Israel AK, Bär KJ. Increased sensitivity to heat pain after sad mood induction in female patients with major depression. Eur J Pain 2010;14:559-63.
21. Lautenbacher S, Krieg JC. Pain perception in psychiatric disorders: a review of the literature. J Psychiatr Res 1994;28:109-22.
22. Adler G, Gattaz WF. Pain perception threshold in major depression. Biol Psychiatry 1993;34:687-9.
23. Bär KJ, Greiner W, Letsch A, Kobele R, Sauer H. Influence of gender and hemispheric lateralization on heat pain perception in major depression. J Psychiatr Res 2003;37:345-53.
24. Dickens C, McGowan L, Dale S. Impact of depression on experimental pain perception: a systematic review of the literature with meta-analysis. Psychosom Med 2003;65:369-75.
25. Strigo IA, Simmons AN, Matthews SC, Craig AD, Paulus MP. Increased affective bias revealed using experimental graded heat stimuli in young depressed adults: evidence of ''emotional allodynia.'' Psychosom Med 2008;70:338-44.
26. Wagner G, Koschke M, Leuf T, Schlosser R, Bär KJ. Reduced heat pain thresholds after sad-mood induction are associated with changes in tha-lamic activity. Neuropsychologia 2009;47:980-7.
27. Klauenberg S, Maier C, Assion HJ, Hoffmann A, Krumova EK, Magerl W, Scherens A, Treede RD, Juckel G. Depression and changed pain perception: hints for a central disinhibition mechanism. Pain 2008;140:332-43.
28. Terhaar J, Viola FC, Franz M, Berger S, Bär KJ, Weiss T. Differential processing of laser stimuli by Adelta and C fibres in major depression. Pain 2011;152:1796-802.
29. Dubner R, Sumino R, Wood WI. A peripheral ''cold'' fiber population responsive to innocuous and noxious thermal stimuli applied to monkey's face. J Neurophysiol 1975;38:1373-89.
30. Schepers RJ, Ringkamp M. Thermoreceptors and thermosensitive afferents. Neurosci Biobehav Rev 2010;34:177-84.
31. Mackenzie RA, Burke D, Skuse NF, Lethlean AK. Fibre function and perception during cutaneous nerve block. J Neurol Neurosurg Psychiatry 1975;38:865-73.
32. Kern D, Pelle-Lancien E, Luce V, Bouhassira D. Pharmacological dissection of the paradoxical pain induced by a thermal grill. Pain 2008;135:291-9.
33. Gescheider GA. Psychophysics: The Fundamentals. 3rd ed. Mahwah, NJ: Lawrence Erlbaum Associates, Inc; 1997.
34. Strigo IA, Simmons AN, Matthews SC, Craig AD, Paulus MP. Association of major depressive disorder with altered functional brain response during anticipation and processing of heat pain. Arch Gen Psychiatry 2008; 65:1275-84.
35. Li X, Petrini L, Wang L, Defrin R, Arendt-Nielsen L. The importance of stimulus parameters for the experience of the thermal grill illusion. Neurophysiol Clin 2009;39:275-82.
36. Defrin R, Benstein-Sheraizin A, Bezalel A, Mantzur O, Arendt-Nielsen L. The spatial characteristics of the painful thermal grill illusion. Pain 2008;138:577-86.
37. Price DD, McHaffie JG, Larson MA. Spatial summation of heat-induced pain: influence of stimulation area and spatial separation on perceived pain sensation intensity and unpleasantness. J Neurophysiol 1989;62:1270-9.