Effect of subcutaneous epinephrine/saline/local anesthetic versus saline-only injection on split-thickness skin graft donor site perfusion, healing, and pain

Journal of Burn Care and Research

Volumn 34, Issue 2, 2013, Pages

  Blome Eberwein, Sigrid ^a   Abboud, Michael ^a   Lozano, Daniel D ^a   Sharma, Rohit ^a   Eid, Sherrine ^a   Gogal, Christina ^a  

^a LEHIGH VALLEY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; LIDOCAINE; POLYURETHAN; ROPIVACAINE; SODIUM CHLORIDE;

ADULT; AGED; ARTICLE; BURN; CLINICAL ARTICLE; CONTROLLED STUDY; DONOR SITE; FEMALE; GRAFT PERFUSION; HUMAN; HYPEREMIA; LOCAL ANESTHESIA; MALE; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SPLIT THICKNESS SKIN GRAFT; SURGICAL EQUIPMENT; SURGICAL TECHNIQUE; WOUND DRESSING; WOUND HEALING;

ADULT; AGED; ANESTHETICS, LOCAL; BLOOD LOSS, SURGICAL; BURNS; EPINEPHRINE; FEMALE; HUMANS; INJECTIONS; INJECTIONS, SUBCUTANEOUS; MALE; MIDDLE AGED; PAIN MEASUREMENT; PROSPECTIVE STUDIES; SKIN TRANSPLANTATION; SODIUM CHLORIDE; TREATMENT OUTCOME; WOUND HEALING;

EID: 84876289750     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0b013e31825d5414     Document Type: Article

References (15)

1. Kahalley L, Dimick AR, Gillespie RW. Methods to diminish intraoperative blood loss. J Burn Care Rehabil 1991;12:160-1
2. Gomez M, Logsetty S, Fish JS. Reduced blood loss during burn surgery. J Burn Care Rehabil 2001;22:111-7
3. Losee JE, Fox I, Hua LB, Cladis FP, Serletti JM. Transfusion- free pediatric burn surgery: Techniques and strategies. Ann Plast Surg 2005;54:165-71
4. Djurickovic S, Snelling CF, Boyle JC. Tourniquet and subcutaneous epinephrine reduce blood loss during burn excision and immediate autografting. J Burn Care Rehabil 2001;22:1-5
5. Barret JP, Dziewulski P, Wolf SE, Desai MH, Nichols RJ 2nd, Herndon DN. Effect of topical and subcutaneous epinephrine in combination with topical thrombin in blood loss during immediate near-total burn wound excision in pediatric burned patients. Burns 1999;25: 509-13
6. Beausang E, Orr D, Shah M, Dunn KW, Davenport PJ. Subcutaneous adrenaline infiltration in paediatric burn surgery. Br J Plast Surg 1999;52:480-1
7. Robertson RD, Bond P, Wallace B, Shewmake K, Cone J. The tumescent technique to significantly reduce blood loss during burn surgery. Burns 2001;27:835-8
8. Mzezewa S, Jönsson K, Aberg M, Sjöberg T, Salemark L. A prospective double blind randomized study comparing the need for blood transfusion with terlipressin or a placebo during early excision and grafting of burns. Burns 2004;30:236-40
9. Cartotto R, Musgrave MA, Beveridge M, Fish J, Gomez M. Minimizing blood loss in burn surgery. J Trauma 2000;49:1034-9
10. Marano MA, O'Sullivan G, Madden M, Finkelstein J, Goodwin CW. Tourniquet technique for reduced blood loss and wound assessment during excisions of burn wounds of the extremity. Surg Gynecol Obstet 1990;171:249-50
11. Missavage AE, Bush RL, Kien ND, Reilly DA. The effect of clysed and topical epinephrine on intraoperative catecholamine levels. J Trauma 1998;45:1074-8
12. Cartotto R, Kadikar N, Musgrave MA, Gomez M, Cooper AB. What are the acute cardiovascular effects of subcutaneous and topical epinephrine for hemostasis during burn surgery? J Burn Care Rehabil 2003;24:297-305
13. Papp AA, Uusaro AV, Ruokonen ET. The effects of topical epinephrine on haemodynamics and markers of tissue perfusion in burned and non-burned patients requiring skin grafting. Burns 2009;35:832-9
14. Alvi R, Jones S, Burrows D, et al. The safety of topical anaesthetic and analgesic agents in a gel when used to provide pain relief at split skin donor sites. Burns 1998;24:54-7
15. Gaufberg SV, Walta MJ, Workman TP. Expanding the use of topical anesthesia in wound management: Sequential layered application of topical lidocaine with epinephrine. Am J Emerg Med 2007;25:379-84