Acidic/neutral amino acid residues substitution in NH2 terminal of plasminogen kringle 5 exerts enhanced effects on corneal neovascularization

Cornea

Volumn 32, Issue 5, 2013, Pages 680-688

  Li, Cen ^a   Li, Lei ^a,b   Cheng, Rui ^c   Dai, Zhiyu ^a   Li, Chaoyang ^d   Yao, Yachao ^a   Zhou, Ti ^a   Yang, Zhonghan ^a   Gao, Guoquan ^a,e   Yang, Xia ^a,f  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d SUN YAT SEN UNIVERSITY   (China)

^e BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^f SUN YAT SEN UNIVERSITY   (China)

Author keywords

antiangiogenesis; apoptosis; corneal neovascularization; mutation; plasminogen kringle 5

Indexed keywords

AMINO ACID; AMMONIA; ANGIOGENESIS INHIBITOR; BROXURIDINE; DNA NUCLEOTIDYLEXOTRANSFERASE; KRINGLE 5; MUTANT KRINGLE 5; PIGMENT EPITHELIUM DERIVED FACTOR; SERINE; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH INHIBITOR;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAUSTIC BURN; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CORNEA NEOVASCULARIZATION; DOWN REGULATION; DRUG EFFICACY; FEMALE; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LABELING INDEX; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; TREATMENT DURATION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

AMINO ACID SUBSTITUTION; AMINO ACIDS, ACIDIC; AMINO ACIDS, NEUTRAL; ANGIOGENESIS INHIBITORS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CORNEAL NEOVASCULARIZATION; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; EYE PROTEINS; FEMALE; FLOW CYTOMETRY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MUTAGENESIS, SITE-DIRECTED; NERVE GROWTH FACTORS; PEPTIDE FRAGMENTS; PLASMINOGEN; RATS; RATS, SPRAGUE-DAWLEY; SERPINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84876286069     PISSN: 02773740     EISSN: 15364798     Source Type: Journal    
DOI: 10.1097/ICO.0b013e3182781ec9     Document Type: Article

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