Encapsulation of naproxen in Eudragit RSPO microsphere system: In vitro characterization and compatibility studies

Dhaka University Journal of Pharmaceutical Sciences

Volumn 11, Issue 2, 2012, Pages 147-155

  Paul, Shovan ^a   Akhter, Sharmin ^b   Hasan, Ikramul ^a   Haider, Syed Shabbir ^a   Reza, Md Selim ^a  

^a UNIVERSITY OF DHAKA   (Bangladesh)

^b UNIVERSITY OF ASIA PACIFIC   (Bangladesh)

Author keywords

Emulsification solvent evaporation method; Eudragit RSPO; Microsphere; Naproxen

Indexed keywords

EUDRAGIT; EUDRAGIT RSPO; MICROSPHERE; NAPROXEN; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG FORMULATION; DRUG INCOMPATIBILITY; DRUG RELEASE; EMULSION; EVAPORATION; IN VITRO STUDY; INFRARED SPECTROSCOPY; MICROENCAPSULATION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

EID: 84876275822     PISSN: 18161820     EISSN: 18161839     Source Type: Journal    
DOI: 10.3329/dujps.v11i2.14573     Document Type: Article

References (10)

1. Zaghloul, A.A., Faltinek, J., Vaithiyalingam, S.R., Reddy, I.K. and Khan, M.A. 2001. Screening of process and formulation variables for the preparation of extended release tablets of Naproxen-Eudragit microspheres. Pharmazie. 56, 321-4
2. Wan, LS. and Chui, WK. 1995. Deviation of the ratio of drugs in a two component mixture encapsulated in cellulose phthalate microspheres. J. Microencapsul. 12, 417-23.
3. Yamuda, T., Onishi, H. and Machida, Y. 2001. Sustained release ketoprofenmicroparticles with ethyl cellulose and carboxymethyl ethyl cellulose. J. Controlled Release. 75, 271-282.
4. Bolourtchian, N., Karimi, K. and Aboofazeli, R. 2005. Preparation and characterization of ibuprofen microspheres. J. Microencapsul. 22, 529-538.
5. Haznedar, S., Dortunc, B. 2004. Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide. Int. J. Pharm. 269, 131-140.
6. Horoz, B., Kiliic, M., Arslan, N., Baykara, Y T. 2004. Effect of different dispersing agents on the characteristics of Eudragit microspheres prepared by a solvent evaporation method. J. Microencapsul. 21, 191-202.
7. Haznedar, S, and Dortue, B. 2004. Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide. Intl. J. Pharm. 269, 131-140.
8. Higuchi, T. 1963. Mechanism of sustained action medication, theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J. Pharm. Sci. 52, 1145-1149.
9. Korsmeyer, RW., Gurny, R., Doelker, EM., Buri, P. and Peppas, N.A. 1983. Mechanism of solute release from porous hydrophilic polymers. Intl. J. Pharm. 15, 25-35.
10. Mello, V.A. and Ricci, R. 2011. Encapsulation of Naproxen in nanosphered system: structural characterization and in vitro release studies Vol. 34, no. 6.