XOMA 052, an anti-IL-1β monoclonal antibody, prevents IL-1β-mediated insulin resistance in 3T3-L1 adipocytes

Obesity

Volumn 21, Issue 2, 2013, Pages 306-309

  Handa, Masahisa ^a   Vanegas, Sandra ^a   Maddux, Betty A ^b   Mendoza, Nerissa ^a   Zhu, Shirley ^a   Goldfine, Ira D ^b   Mirza, Amer M ^a  

^a XOMA Corporation   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GEVOKIZUMAB; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; LIPID; PROTEIN KINASE B; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ADIPOCYTE; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME PHOSPHORYLATION; FATTY ACID TRANSPORT; GLUCOSE TRANSPORT; IN VITRO STUDY; INSULIN RESISTANCE; LIPID METABOLISM; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; APOPTOSIS; ARABIDOPSIS PROTEINS; CELL DIFFERENTIATION; CYTOKINES; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; INFLAMMATION; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; INTRAMOLECULAR TRANSFERASES; LIPID METABOLISM; MICE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84876264923     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.20004     Document Type: Article

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