-
1
-
-
84862070237
-
Maintaining differentiated cellular identity
-
Holmberg J, Perlmann T (2012) Maintaining differentiated cellular identity. Nat Rev Genet 13(6):429-439.
-
(2012)
Nat Rev Genet
, vol.13
, Issue.6
, pp. 429-439
-
-
Holmberg, J.1
Perlmann, T.2
-
2
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4):663-676.
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
3
-
-
84865786819
-
Lineage conversion methodologies meet the reprogramming toolbox
-
Sancho-Martinez I, Baek SH, Izpisua Belmonte JC (2012) Lineage conversion methodologies meet the reprogramming toolbox. Nat Cell Biol 14(9):892-899.
-
(2012)
Nat Cell Biol
, vol.14
, Issue.9
, pp. 892-899
-
-
Sancho-Martinez, I.1
Baek, S.H.2
Izpisua Belmonte, J.C.3
-
4
-
-
79952900560
-
Turning straw into gold: Directing cell fate for regenerative medicine
-
Cohen DE, Melton D (2011) Turning straw into gold: Directing cell fate for regenerative medicine. Nat Rev Genet 12(4):243-252.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.4
, pp. 243-252
-
-
Cohen, D.E.1
Melton, D.2
-
5
-
-
84866361701
-
Circuitry and dynamics of human transcription factor regulatory networks
-
Neph S, et al. (2012) Circuitry and dynamics of human transcription factor regulatory networks. Cell 150(6):1274-1286.
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1274-1286
-
-
Neph, S.1
-
6
-
-
77956320116
-
Functional genomics reveals a BMP-driven mes-enchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani P, et al. (2010) Functional genomics reveals a BMP-driven mes-enchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7(1):64-77.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.1
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
-
7
-
-
54949105021
-
Promotion of reprogramming to ground state pluripotency by signal inhibition
-
Silva J, et al. (2008) Promotion of reprogramming to ground state pluripotency by signal inhibition. PLoS Biol 6(10):e253.
-
(2008)
PLoS Biol
, vol.6
, Issue.10
-
-
Silva, J.1
-
8
-
-
41949098160
-
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
-
Hanna J, et al. (2008) Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133(2):250-264.
-
(2008)
Cell
, vol.133
, Issue.2
, pp. 250-264
-
-
Hanna, J.1
-
9
-
-
24944484633
-
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
-
Conti L, et al. (2005) Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol 3(9):e283.
-
(2005)
PLoS Biol
, vol.3
, Issue.9
-
-
Conti, L.1
-
10
-
-
84862777308
-
Direct reprogramming of fibroblasts into neural stem cells by defined factors
-
Han DW, et al. (2012) Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell 10(4):465-472.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.4
, pp. 465-472
-
-
Han, D.W.1
-
11
-
-
20544473735
-
The initiation of liver development is dependent on Foxa transcription factors
-
Lee CS, Friedman JR, Fulmer JT, Kaestner KH (2005) The initiation of liver development is dependent on Foxa transcription factors. Nature 435(7044):944-947.
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 944-947
-
-
Lee, C.S.1
Friedman, J.R.2
Fulmer, J.T.3
Kaestner, K.H.4
-
12
-
-
0034090310
-
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
-
Li J, Ning G, Duncan SA (2000) Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev 14(4):464-474.
-
(2000)
Genes Dev
, vol.14
, Issue.4
, pp. 464-474
-
-
Li, J.1
Ning, G.2
Duncan, S.A.3
-
13
-
-
79952846468
-
Progress in understanding reprogramming to the induced pluripotent state
-
Plath K, Lowry WE (2011) Progress in understanding reprogramming to the induced pluripotent state. Nat Rev Genet 12(4):253-265.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.4
, pp. 253-265
-
-
Plath, K.1
Lowry, W.E.2
-
14
-
-
80054728495
-
Animal transcription networks as highly connected, quantitative continua
-
Biggin MD (2011) Animal transcription networks as highly connected, quantitative continua. Dev Cell 21(4):611-626.
-
(2011)
Dev Cell
, vol.21
, Issue.4
, pp. 611-626
-
-
Biggin, M.D.1
-
15
-
-
80053240481
-
Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation
-
Yang CS, Lopez CG, Rana TM (2011) Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation. Stem Cells 29(10):1528-1536.
-
(2011)
Stem Cells
, vol.29
, Issue.10
, pp. 1528-1536
-
-
Yang, C.S.1
Lopez, C.G.2
Rana, T.M.3
-
16
-
-
84871586080
-
A molecular roadmap of reprogramming somatic cells into iPS cells
-
Polo JM, et al. (2012) A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 151(7):1617-1632.
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1617-1632
-
-
Polo, J.M.1
-
17
-
-
84870058502
-
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome
-
Soufi A, Donahue G, Zaret KS (2012) Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell 151(5):994-1004.
-
(2012)
Cell
, vol.151
, Issue.5
, pp. 994-1004
-
-
Soufi, A.1
Donahue, G.2
Zaret, K.S.3
-
18
-
-
84866369892
-
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
-
Buganim Y, et al. (2012) Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell 150(6):1209-1222.
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1209-1222
-
-
Buganim, Y.1
-
19
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer LA, et al. (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441(7091):349-353.
-
(2006)
Nature
, vol.441
, Issue.7091
, pp. 349-353
-
-
Boyer, L.A.1
-
20
-
-
44449104974
-
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity
-
Endoh M, et al. (2008) Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development 135(8):1513-1524.
-
(2008)
Development
, vol.135
, Issue.8
, pp. 1513-1524
-
-
Endoh, M.1
-
21
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li R, et al. (2010) A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7(1): 51-63.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.1
, pp. 51-63
-
-
Li, R.1
-
22
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139(5):871-890.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
23
-
-
33746034613
-
Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition
-
Thuault S, et al. (2006) Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition. J Cell Biol 174(2):175-183.
-
(2006)
J Cell Biol
, vol.174
, Issue.2
, pp. 175-183
-
-
Thuault, S.1
-
24
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Dunham I, et al.; ENCODE Project Consortium (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489(7414):57-74.
-
(2012)
Nature
, vol.489
, Issue.7414
, pp. 57-74
-
-
Dunham, I.1
-
25
-
-
83255188897
-
Polycomb-repressed genes have permissive enhancers that initiate reprogramming
-
Taberlay PC, et al. (2011) Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell 147(6):1283-1294.
-
(2011)
Cell
, vol.147
, Issue.6
, pp. 1283-1294
-
-
Taberlay, P.C.1
-
26
-
-
40749104852
-
An extended transcriptional network for pluripotency of embryonic stem cells
-
Kim J, Chu J, Shen X, Wang J, Orkin SH (2008) An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132(6):1049-1061.
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 1049-1061
-
-
Kim, J.1
Chu, J.2
Shen, X.3
Wang, J.4
Orkin, S.H.5
-
27
-
-
44649117905
-
Integration of external signaling pathways with the core tran-scriptional network in embryonic stem cells
-
Chen X, et al. (2008) Integration of external signaling pathways with the core tran-scriptional network in embryonic stem cells. Cell 133(6):1106-1117.
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1106-1117
-
-
Chen, X.1
-
28
-
-
79953016856
-
MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells
-
Watanabe S, et al. (2011) MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells. Stem Cells 29(3):505-516.
-
(2011)
Stem Cells
, vol.29
, Issue.3
, pp. 505-516
-
-
Watanabe, S.1
-
29
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron R, Reinberg D (2011) The Polycomb complex PRC2 and its mark in life. Nature 469(7330):343-349.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
30
-
-
78651486442
-
Densely interconnected transcriptional circuits control cell states in human hematopoiesis
-
Novershtern N, et al. (2011) Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 144(2):296-309.
-
(2011)
Cell
, vol.144
, Issue.2
, pp. 296-309
-
-
Novershtern, N.1
-
31
-
-
79960649307
-
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
-
Sekiya S, Suzuki A (2011) Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature 475(7356):390-393.
-
(2011)
Nature
, vol.475
, Issue.7356
, pp. 390-393
-
-
Sekiya, S.1
Suzuki, A.2
-
32
-
-
79960637387
-
Induction of functional hepatocyte-like cells from mouse fi-broblasts by defined factors
-
Huang P, et al. (2011) Induction of functional hepatocyte-like cells from mouse fi-broblasts by defined factors. Nature 475(7356):386-389.
-
(2011)
Nature
, vol.475
, Issue.7356
, pp. 386-389
-
-
Huang, P.1
-
33
-
-
33747370376
-
Plasticity and expanding complexity of the hepatic transcription factor network during liver development
-
Kyrmizi I, et al. (2006) Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev 20(16):2293-2305.
-
(2006)
Genes Dev
, vol.20
, Issue.16
, pp. 2293-2305
-
-
Kyrmizi, I.1
-
34
-
-
84859218238
-
Chromatin-modifying enzymes as modulators of reprogramming
-
Onder TT, et al. (2012) Chromatin-modifying enzymes as modulators of reprogramming. Nature 483(7391):598-602.
-
(2012)
Nature
, vol.483
, Issue.7391
, pp. 598-602
-
-
Onder, T.T.1
-
35
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, et al. (2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 40(5):499-507.
-
(2008)
Nat Genet
, vol.40
, Issue.5
, pp. 499-507
-
-
Ben-Porath, I.1
-
36
-
-
34848853915
-
Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors
-
Cobaleda C, Jochum W, Busslinger M (2007) Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature 449(7161): 473-477.
-
(2007)
Nature
, vol.449
, Issue.7161
, pp. 473-477
-
-
Cobaleda, C.1
Jochum, W.2
Busslinger, M.3
-
37
-
-
75149195336
-
The transcriptional network for mesenchymal transformation of brain tumours
-
Carro MS, et al. (2010) The transcriptional network for mesenchymal transformation of brain tumours. Nature 463(7279):318-325.
-
(2010)
Nature
, vol.463
, Issue.7279
, pp. 318-325
-
-
Carro, M.S.1
|