-
1
-
-
84856158305
-
ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
-
Hamm CW, Bassand J-P, Agewall S, et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2011;32:2999-3054
-
(2011)
Eur Heart J
, vol.32
, pp. 2999-3054
-
-
Hamm, C.W.1
Bassand, J.-P.2
Agewall, S.3
-
2
-
-
45949090749
-
Antithrombotic therapy for non- ST-segment elevation acute coronary syndromes: American college of chest physicians evidence-based clinical practice guidelines
-
(8th Edition)
-
Harrington RA, Becker RC, Cannon CP, et al. Antithrombotic therapy for non- ST-segment elevation acute coronary syndromes: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133(6 Suppl):670-707S
-
(2008)
Chest
, vol.133
, Issue.6 SUPPL.
-
-
Harrington, R.A.1
Becker, R.C.2
Cannon, C.P.3
-
3
-
-
70449484408
-
Ticagrelor: The first reversibly binding oral P2Y12 receptor antagonist
-
Husted S, van Giezen JJ. Ticagrelor: the first reversibly binding oral P2Y12 receptor antagonist. Cardiovasc Ther 2009;27:259-74
-
(2009)
Cardiovasc Ther
, vol.27
, pp. 259-274
-
-
Husted, S.1
Van Giezen, J.J.2
-
4
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009;361:1045-57
-
(2009)
N Engl J Med
, vol.361
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
-
5
-
-
33646261670
-
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin
-
rely 1505-6
-
Husted S, Emanuelsson H, Heptinstall S, et al. Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin. Eur Heart J 2006;27:1038-47, reply 1505-6
-
(2006)
Eur Heart J
, vol.27
, pp. 1038-1047
-
-
Husted, S.1
Emanuelsson, H.2
Heptinstall, S.3
-
6
-
-
35548995394
-
Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: Primary results of the DISPERSE-2 trial
-
Cannon CP, Husted S, Harrington RA, et al. Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 trial. J Am Coll Cardiol 2007;50:1844-51
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 1844-1851
-
-
Cannon, C.P.1
Husted, S.2
Harrington, R.A.3
-
7
-
-
77955110385
-
Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study
-
Storey RF, Bliden KP, Patil SB, et al. Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study. J Am Coll Cardiol 2010;56:185-93
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 185-193
-
-
Storey, R.F.1
Bliden, K.P.2
Patil, S.B.3
-
8
-
-
62949141274
-
Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet Inhibition and Patient Outcomes (PLATO) trial
-
James S, Akerblom A, Cannon CP, et al. Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: rationale, design, and baseline characteristics of the PLATelet Inhibition and Patient Outcomes (PLATO) trial. Am Heart J 2009;157:599-605
-
(2009)
Am Heart J
, vol.157
, pp. 599-605
-
-
James, S.1
Akerblom, A.2
Cannon, C.P.3
-
9
-
-
80955144190
-
Pulmonary function in patients with acute coronary syndromes treated with ticagrelor or clopidogrel from the PLATelet inhibition and patient Outcomes (PLATO) pulmonary function substudy
-
Storey RF, Becker RC, Harrington RA, et al. Pulmonary function in patients with acute coronary syndromes treated with ticagrelor or clopidogrel from the PLATelet inhibition and patient Outcomes (PLATO) pulmonary function substudy. Am J Cardiol 2011;108:1542-6
-
(2011)
Am J Cardiol
, vol.108
, pp. 1542-1546
-
-
Storey, R.F.1
Becker, R.C.2
Harrington, R.A.3
-
10
-
-
77953498801
-
Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers
-
Butler K, Teng R. Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers. Br J Clin Pharmacol 2010;70:65-77
-
(2010)
Br J Clin Pharmacol
, vol.70
, pp. 65-77
-
-
Butler, K.1
Teng, R.2
-
11
-
-
84876205079
-
Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers
-
Teng R, Mitchell P, Butler R. Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers. Eur J Clin Pharmacol 2013;69:477-87
-
(2013)
Eur J Clin Pharmacol
, vol.69
, pp. 477-487
-
-
Teng, R.1
Mitchell, P.2
Butler, R.3
-
13
-
-
78651334110
-
Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease
-
Muskulus M, Slats AM, Sterk S, et al. Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease. J Appl Physiol 2010;109:1582-91
-
(2010)
J Appl Physiol
, vol.109
, pp. 1582-1591
-
-
Muskulus, M.1
Slats, A.M.2
Sterk, S.3
-
14
-
-
0029090616
-
Standardization of spirometry, 1994 update
-
American Thoracic Society
-
American Thoracic Society. Standardization of spirometry,1994 update. Am J Respir Crit Care Med 1995;152:1107-36
-
Am J Respir Crit Care Med
, vol.1995
, Issue.152
, pp. 1107-1136
-
-
-
15
-
-
0027931718
-
Perception of breathlessness during exercise in patients with respiratory disease
-
Mahler DA, Horowitz MB. Perception of breathlessness during exercise in patients with respiratory disease. Med Sci Sports Exerc 1994;26:1078-81
-
(1994)
Med Sci Sports Exerc
, vol.26
, pp. 1078-1081
-
-
Mahler, D.A.1
Horowitz, M.B.2
-
16
-
-
0023685510
-
Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise
-
O'Donnell DE, Sanii R, Giesbrecht G, et al. Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise. Am Rev Respir Dis 1988;138:1185-91
-
(1988)
Am Rev Respir Dis
, vol.138
, pp. 1185-1191
-
-
O'Donnell, D.E.1
Sanii, R.2
Giesbrecht, G.3
-
17
-
-
0031760347
-
Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease
-
O'Donnell DE, Lam M, Webb KA. Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;158:1557-65
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1557-1565
-
-
O'Donnell, D.E.1
Lam, M.2
Webb, K.A.3
-
18
-
-
0027358977
-
Exertional breathlessness in patients with chronic airflow limitation: The role of lung hyperinflation
-
O'Donnell DE, Webb KA. Exertional breathlessness in patients with chronic airflow limitation: the role of lung hyperinflation. Am Rev Respir Dis 1993;148:1351-7
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1351-1357
-
-
O'Donnell, D.E.1
Webb, K.A.2
-
19
-
-
77955846807
-
Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry
-
Sillé n H, Cook M, Davis P. Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry. J Chromatogr B 2010;878:2299-306
-
(2010)
J Chromatogr B
, vol.878
, pp. 2299-2306
-
-
Sillén, H.1
Cook, M.2
Davis, P.3
-
20
-
-
0003443998
-
-
American Thoracic Society. [Last accessed 12 January 2012]
-
Brilique, summary of product characteristics, 2010. Available at: http://www. ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/ human/001241/WC500100494.pdf [Last accessed 12 January 2012]
-
(2010)
Summary of Product Characteristics
-
-
Brilique1
-
21
-
-
84876259242
-
-
Brilinta US Full Prescribing Information July [Last accessed 12 January 2012]
-
Brilinta, US full prescribing information, July 2011. Available at: http://www.accessdata.fda.gov/drugsatfda-docs/label/2011/022433s000lbl.pdf [Last accessed 12 January 2012]
-
(2011)
-
-
-
23
-
-
77954468084
-
Pharmacokinetics, pharmacodynamics, tolerability, and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y12 receptor antagonist, in healthy subjects
-
Teng R, Butler K. Pharmacokinetics, pharmacodynamics, tolerability, and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y12 receptor antagonist, in healthy subjects. Eur J Clin Pharmacol 2010;66:487-96
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 487-496
-
-
Teng, R.1
Butler, K.2
-
24
-
-
35548933800
-
Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes
-
Storey RF, Husted S, Harrington RA, et al. Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes. J Am Coll Cardiol 2007;50:1852-6
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 1852-1856
-
-
Storey, R.F.1
Husted, S.2
Harrington, R.A.3
-
25
-
-
84876260597
-
Evaluation of the pharmacokinetic interaction between ticagrelor and tolbutamide, a cytochrome P45 2C9 substrate, in healthy volunteers
-
[Epub ahead of print]
-
Teng R, Mitchell P, Butler R. Evaluation of the pharmacokinetic interaction between ticagrelor and tolbutamide, a cytochrome P45 2C9 substrate, in healthy volunteers. Int J Clin Pharmacol Ther 2013; [Epub ahead of print]
-
(2013)
Int J Clin Pharmacol Ther
-
-
Teng, R.1
Mitchell, P.2
Butler, R.3
-
26
-
-
33745725932
-
Dyspnea after AZD6140: Safety first?
-
Serebruany VL. Dyspnea after AZD6140: safety first? Eur Heart J 2006;27:1505
-
(2006)
Eur Heart J
, vol.27
, pp. 1505
-
-
Serebruany, V.L.1
-
27
-
-
71849109776
-
Ticagrelor versus clopidogrel in acute coronary syndromes
-
Tomoda H. Ticagrelor versus clopidogrel in acute coronary syndromes. N Engl J Med 2009;361:2385, author reply 2387-8
-
(2009)
N Engl J Med
, vol.361
, Issue.2385
, pp. 2387-2388
-
-
Tomoda, H.1
-
28
-
-
84873712137
-
Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans - A singlecenter, randomized, double-blind, placebo-controlled, crossover study using transthoracic color Doppler echocardiography
-
Wittfeldt A, Emanuelsson H, Brandup-Wognsen G, et al. Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans - a singlecenter, randomized, double-blind, placebo-controlled, crossover study using transthoracic color Doppler echocardiography. J Am Coll Cardiol 2013;61:723-7
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 723-727
-
-
Wittfeldt, A.1
Emanuelsson, H.2
Brandup-Wognsen, G.3
-
29
-
-
11144327709
-
Intravenous adenosine and dyspnea in humans
-
Burki NK, Dale WJ, Lee LY. Intravenous adenosine and dyspnea in humans. J Appl Physiol 2005;98:180-5
-
(2005)
J Appl Physiol
, vol.98
, pp. 180-185
-
-
Burki, N.K.1
Dale, W.J.2
Lee, L.Y.3
-
30
-
-
84876228478
-
Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism
-
[Submitted]
-
Nylander S, Femia E, Scavone M, et al. Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism. J Thromb Haemost 2013 [Submitted]
-
(2013)
J Thromb Haemost
-
-
Nylander, S.1
Femia, E.2
Scavone, M.3
-
31
-
-
0025878633
-
Na(+)-dependent, concentrative nucleoside transport in rat macrophages. Specificity for natural nucleosides and nucleoside analogs, including dideoxynucleosides, and comparison of nucleoside transport in rat, mouse and human macrophages
-
Plagemann PG. Na(+)-dependent, concentrative nucleoside transport in rat macrophages. Specificity for natural nucleosides and nucleoside analogs, including dideoxynucleosides, and comparison of nucleoside transport in rat, mouse and human macrophages. Biochem Pharmacol 1991;42:247-52
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 247-252
-
-
Plagemann, P.G.1
-
32
-
-
0034708596
-
Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine
-
Ward JL, Sherali A, Mo ZP, et al. Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine. J Biol Chem 2000;275:8375-81
-
(2000)
J Biol Chem
, vol.275
, pp. 8375-8381
-
-
Ward, J.L.1
Sherali, A.2
Mo, Z.P.3
-
33
-
-
84866479608
-
Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperaemia responses in a canine model
-
van Giezen JJJ, Sidaway J, Glaves P, et al. Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperaemia responses in a canine model. J Cardiovasc Pharmacol Therap 2012;17:164-72
-
(2012)
J Cardiovasc Pharmacol Therap
, vol.17
, pp. 164-172
-
-
Van Giezen Jjj1
Sidaway, J.2
Glaves, P.3
-
35
-
-
82955201646
-
Characterisation of dyspnea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes
-
Storey RF, Becker RC, Harrington RA, et al. Characterisation of dyspnea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. Eur Heart J 2011;32:2945-53
-
(2011)
Eur Heart J
, vol.32
, pp. 2945-2953
-
-
Storey, R.F.1
Becker, R.C.2
Harrington, R.A.3
|