Sensitive, high throughput detection of proteins in individual, surfactant-stabilized picoliter droplets using nanoelectrospray ionization mass spectrometry

Analytical Chemistry

Volumn 85, Issue 8, 2013, Pages 3812-3816

  Smith, Clive A ^a,d   Li, Xin ^a,d   Mize, Todd H ^a,e   Sharpe, Timothy D ^a,f   Graziani, Edmund I ^b   Abell, Chris ^a   Huck, Wilhelm T S ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER INC   (United States)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^d SPHERE FLUIDICS LIMITED   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSPRAY IONIZATION MASS SPECTROMETRY; FEMTOMOLE QUANTITIES; HIGH THROUGHPUT SCREENING; HIGH-THROUGHPUT DETECTION; INDIVIDUAL DROPLETS; MICRO-FLUIDIC DEVICES; NANOELECTROSPRAY IONIZATION MASS SPECTROMETRY; SURFACTANT-STABILIZED;

EMULSIFICATION; FLUIDIC DEVICES; FLUIDICS; MASS SPECTROMETERS; MASS SPECTROMETRY; PROTEINS;

DROP FORMATION;

CARBONATE DEHYDRATASE; CHYMOTRYPSINOGEN; CYTOCHROME C; FLUOROCARBON; LYSOZYME; OIL; SURFACTANT;

ARTICLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EMULSION; EQUIPMENT; FLOW INJECTION ANALYSIS; HIGH THROUGHPUT SCREENING; METHODOLOGY; MICROFLUIDIC ANALYSIS; NANOTECHNOLOGY;

CARBONIC ANHYDRASES; CHYMOTRYPSINOGEN; CYTOCHROMES C; EMULSIONS; FLOW INJECTION ANALYSIS; FLUOROCARBONS; HIGH-THROUGHPUT SCREENING ASSAYS; INDUSTRIAL OILS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MURAMIDASE; NANOTECHNOLOGY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SURFACE-ACTIVE AGENTS;

EID: 84876253828     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac400453t     Document Type: Article

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