메뉴 건너뛰기




Volumn 92, Issue 3, 2012, Pages 347-352

Gene therapy for cancer: Is there light at the end of the tunnel?

Author keywords

[No Author keywords available]

Indexed keywords

CANCER GENE THERAPY; CLINICAL TRIAL; GENE DELIVERY; REGULATORY BODIES; TUMOUR CELLS;

EID: 84876250649     PISSN: 09704140     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (3)

References (36)
  • 1
    • 0038446699 scopus 로고    scopus 로고
    • Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: Long-term results of the first clinical gene therapy trial
    • Muul LM, Tuschong LM, Soenen SL, Jagadeesh GJ, Ramsey WJ, Long Z, Carter CS, Garabedian EK, Alleyne M, Brown M et al: Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial. Blood 2003, 101(7):2563-2569.
    • (2003) Blood , vol.101 , Issue.7 , pp. 2563-2569
    • Muul, L.M.1    Tuschong, L.M.2    Soenen, S.L.3    Jagadeesh, G.J.4    Ramsey, W.J.5    Long, Z.6    Carter, C.S.7    Garabedian, E.K.8    Alleyne, M.9    Brown, M.10
  • 3
    • 0034328925 scopus 로고    scopus 로고
    • Gene therapy: Trials and tribulations
    • Somia N, Verma IM: Gene therapy: trials and tribulations. Nat Rev Genet 2000, 1(2):91-99.
    • (2000) Nat Rev Genet , vol.1 , Issue.2 , pp. 91-99
    • Somia, N.1    Verma, I.M.2
  • 6
    • 32344443105 scopus 로고    scopus 로고
    • China offers alternative gateway for experimental drugs
    • Jia H, Kling J: China offers alternative gateway for experimental drugs. Nat Biotechnol 2006, 24(2):117-118.
    • (2006) Nat Biotechnol , vol.24 , Issue.2 , pp. 117-118
    • Jia, H.1    Kling, J.2
  • 7
    • 80053512134 scopus 로고    scopus 로고
    • Gene therapies advance towards finish line
    • Mullard A: Gene therapies advance towards finish line. Nat Rev Drug Discov 2011, 10(10):719-720.
    • (2011) Nat Rev Drug Discov , vol.10 , Issue.10 , pp. 719-720
    • Mullard, A.1
  • 8
    • 84860373838 scopus 로고    scopus 로고
    • Glybera and the future of gene therapy in the European Union
    • Miller N: Glybera and the future of gene therapy in the European Union. Nat Rev Drug Discov 2012, 11(5):419.
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.5 , pp. 419
    • Miller, N.1
  • 9
    • 0034694011 scopus 로고    scopus 로고
    • A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
    • Rainov NG: A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther 2000, 11(17):2389-2401.
    • (2000) Hum Gene Ther , vol.11 , Issue.17 , pp. 2389-2401
    • Rainov, N.G.1
  • 10
    • 79751506542 scopus 로고    scopus 로고
    • Gene therapy finds its niche
    • Sheridan C: Gene therapy finds its niche. Nat Biotechnol 2011, 29(2):121-128.
    • (2011) Nat Biotechnol , vol.29 , Issue.2 , pp. 121-128
    • Sheridan, C.1
  • 11
    • 38449107235 scopus 로고    scopus 로고
    • Replication-competent retrovirus vectors for cancer gene therapy
    • Tai CK, Kasahara N: Replication-competent retrovirus vectors for cancer gene therapy. Front Biosci 2008, 13:3083-3095.
    • (2008) Front Biosci , vol.13 , pp. 3083-3095
    • Tai, C.K.1    Kasahara, N.2
  • 13
  • 14
    • 33645873289 scopus 로고    scopus 로고
    • Recent advances in non-viral gene delivery
    • Conwell CC, Huang L: Recent Advances in Non-viral Gene Delivery. Adv Genet 2005, 53PA:1-18.
    • (2005) Adv Genet , vol.53 PA , pp. 1-18
    • Conwell, C.C.1    Huang, L.2
  • 15
    • 42649109659 scopus 로고    scopus 로고
    • Immuno-gene therapy approaches for cancer: From in vitro studies to clinical trials
    • Loisel-Meyer S, Foley R, Medin JA: Immuno-gene therapy approaches for cancer: from in vitro studies to clinical trials. Front Biosci 2008, 13:3202-3214.
    • (2008) Front Biosci , vol.13 , pp. 3202-3214
    • Loisel-Meyer, S.1    Foley, R.2    Medin, J.A.3
  • 16
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: Harnessing the T cell response
    • Restifo NP, Dudley ME, Rosenberg SA: Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 2012, 12(4):269-281.
    • (2012) Nat Rev Immunol , vol.12 , Issue.4 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 17
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M: Immunity, inflammation, and cancer. Cell 2010, 140(6):883-899.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 18
    • 84861215805 scopus 로고    scopus 로고
    • Tumor-targeted TNFalpha stabilizes tumor vessels and enhances active immunotherapy
    • Johansson A, Hamzah J, Payne CJ, Ganss R: Tumor-targeted TNFalpha stabilizes tumor vessels and enhances active immunotherapy. Proc Natl Acad Sci U S A 2012, 109(20):7841-7846.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.20 , pp. 7841-7846
    • Johansson, A.1    Hamzah, J.2    Payne, C.J.3    Ganss, R.4
  • 19
    • 84860713852 scopus 로고    scopus 로고
    • Sipuleucel-T (Provenge) autologous vaccine approved for treatment of men with asymptomatic or minimally symptomatic castrate-resistant metastatic prostate cancer
    • Gardner T, Elzey B, Hahn NM: Sipuleucel-T (Provenge) autologous vaccine approved for treatment of men with asymptomatic or minimally symptomatic castrate-resistant metastatic prostate cancer. Hum Vaccin Immunother 2012, 8(4):534-539.
    • (2012) Hum Vaccin Immunother , vol.8 , Issue.4 , pp. 534-539
    • Gardner, T.1    Elzey, B.2    Hahn, N.M.3
  • 20
    • 77958481129 scopus 로고    scopus 로고
    • Genetically modified dendritic cells in cancer immunotherapy: A better tomorrow?
    • Shurin MR, Gregory M, Morris JC, Malyguine AM: Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow? Expert Opin Biol Ther 2010, 10(11):1539-1553.
    • (2010) Expert Opin Biol Ther , vol.10 , Issue.11 , pp. 1539-1553
    • Shurin, M.R.1    Gregory, M.2    Morris, J.C.3    Malyguine, A.M.4
  • 21
    • 84861171729 scopus 로고    scopus 로고
    • Dendritic/tumor fusion cells as cancer vaccines
    • Avigan D, Rosenblatt J, Kufe D: Dendritic/tumor fusion cells as cancer vaccines. Semin Oncol 2012, 39(3):287-295.
    • (2012) Semin Oncol , vol.39 , Issue.3 , pp. 287-295
    • Avigan, D.1    Rosenblatt, J.2    Kufe, D.3
  • 22
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten FL: Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986, 46(10):5276-5281.
    • (1986) Cancer Res , vol.46 , Issue.10 , pp. 5276-5281
    • Moolten, F.L.1
  • 23
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy
    • Bi WL, Parysek LM, Warnick R, Stambrook PJ: In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy. Hum Gene Ther 1993, 4(6):725-731.
    • (1993) Hum Gene Ther , vol.4 , Issue.6 , pp. 725-731
    • Bi, W.L.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 24
    • 0032410437 scopus 로고    scopus 로고
    • Preclinical studies on suicide gene therapy for head/neck cancer: A novel method for evaluation of treatment efficacy
    • Thomas SM, Naresh KN, Wagle AS, Mulherkar R: Preclinical studies on suicide gene therapy for head/neck cancer: a novel method for evaluation of treatment efficacy. Anticancer Res 1998, 18(6 A):4393-4398.
    • (1998) Anticancer Res , vol.18 , Issue.6 A , pp. 4393-4398
    • Thomas, S.M.1    Naresh, K.N.2    Wagle, A.S.3    Mulherkar, R.4
  • 27
    • 33947279386 scopus 로고    scopus 로고
    • Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy
    • Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson TC, Kumon H: Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy. Mol Ther 2007, 15(4):834-840.
    • (2007) Mol Ther , vol.15 , Issue.4 , pp. 834-840
    • Nasu, Y.1    Saika, T.2    Ebara, S.3    Kusaka, N.4    Kaku, H.5    Abarzua, F.6    Manabe, D.7    Thompson, T.C.8    Kumon, H.9
  • 30
    • 73449102542 scopus 로고    scopus 로고
    • HDAC inhibitor valproic acid enhances tumor cell kill in adenovirus-HSVtk mediated suicide gene therapy in HNSCC xenograft mouse model
    • Kothari V, Joshi G, Nama S, Somasundaram K, Mulherkar R: HDAC inhibitor valproic acid enhances tumor cell kill in adenovirus-HSVtk mediated suicide gene therapy in HNSCC xenograft mouse model. Int J Cancer 2010, 126(3):733-742.
    • (2010) Int J Cancer , vol.126 , Issue.3 , pp. 733-742
    • Kothari, V.1    Joshi, G.2    Nama, S.3    Somasundaram, K.4    Mulherkar, R.5
  • 31
    • 84855507072 scopus 로고    scopus 로고
    • Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia
    • Cortes J, Kantarjian H, Ball ED, Dipersio J, Kolitz JE, Fernandez HF, Goodman M, Borthakur G, Baer MR, Wetzler M: Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia. Cancer 2012, 118(2):418-427.
    • (2012) Cancer , vol.118 , Issue.2 , pp. 418-427
    • Cortes, J.1    Kantarjian, H.2    Ball, E.D.3    Dipersio, J.4    Kolitz, J.E.5    Fernandez, H.F.6    Goodman, M.7    Borthakur, G.8    Baer, M.R.9    Wetzler, M.10
  • 33
    • 67649386118 scopus 로고    scopus 로고
    • Concepts in in vivo siRNA delivery for cancer therapy
    • Gondi CS, Rao JS: Concepts in in vivo siRNA delivery for cancer therapy. J Cell Physiol 2009, 220(2):285-291.
    • (2009) J Cell Physiol , vol.220 , Issue.2 , pp. 285-291
    • Gondi, C.S.1    Rao, J.S.2
  • 34
    • 24944454988 scopus 로고    scopus 로고
    • Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
    • Peng Z: Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum Gene Ther 2005, 16(9):1016-1027.
    • (2005) Hum Gene Ther , vol.16 , Issue.9 , pp. 1016-1027
    • Peng, Z.1
  • 36
    • 84856179133 scopus 로고    scopus 로고
    • French institute prepares for gene-therapy push
    • Abbott A: French institute prepares for gene-therapy push. Nature 2012, 481(7382):423-424.
    • (2012) Nature , vol.481 , Issue.7382 , pp. 423-424
    • Abbott, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.