메뉴 건너뛰기




Volumn 27, Issue 4, 2013, Pages 961-964

The influence of hypoxia on CML trafficking through modulation of CXCR4 and E-cadherin expression

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; IMATINIB; NILOTINIB; UVOMORULIN;

EID: 84876159957     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.353     Document Type: Letter
Times cited : (17)

References (15)
  • 1
    • 0034670036 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukemia
    • Deininger MWN, Goldman JM, Melo JV. The molecular biology of chronic myeloid leukemia. Blood 2000; 96: 3343-3356.
    • (2000) Blood , vol.96 , pp. 3343-3356
    • Deininger, M.W.N.1    Goldman, J.M.2    Melo, J.V.3
  • 2
    • 0141455972 scopus 로고    scopus 로고
    • Localization of BCR-ABL to F-actin regulates cell adhesion but does not attenuate CML development
    • Wertheim JA, Perera SA, Hammer DA, Ren R, Boettiger D, Pear WS. Localization of BCR-ABL to F-actin regulates cell adhesion but does not attenuate CML development. Blood 2003; 102: 2220-2228.
    • (2003) Blood , vol.102 , pp. 2220-2228
    • Wertheim, J.A.1    Perera, S.A.2    Hammer, D.A.3    Ren, R.4    Boettiger, D.5    Pear, W.S.6
  • 5
    • 84859832491 scopus 로고    scopus 로고
    • Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia
    • Zhang B, Ho YW, Huang Q, Maeda T, Lin A, Lee SU et al. Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia. Cancer Cell 2012a; 21: 577-592.
    • (2012) Cancer Cell , vol.21 , pp. 577-592
    • Zhang, B.1    Ho, Y.W.2    Huang, Q.3    Maeda, T.4    Lin, A.5    Lee, S.U.6
  • 6
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
    • Mahon FX, Rea D, Guilhot J, Guilhot F, Huguet F, Nicolini F et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol 2010; 11: 1029-1035.
    • (2010) Lancet Oncol , vol.11 , pp. 1029-1035
    • Mahon, F.X.1    Rea, D.2    Guilhot, J.3    Guilhot, F.4    Huguet, F.5    Nicolini, F.6
  • 7
    • 42349116071 scopus 로고    scopus 로고
    • Enhanced BCRABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors
    • Konig H, Holtz M, Modi H, Manley P, Holyoake TL, Forman SJ et al. Enhanced BCRABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors. Leukemia 2008; 22: 748-755.
    • (2008) Leukemia , vol.22 , pp. 748-755
    • Konig, H.1    Holtz, M.2    Modi, H.3    Manley, P.4    Holyoake, T.L.5    Forman, S.J.6
  • 8
    • 38349086394 scopus 로고    scopus 로고
    • CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells
    • Jin L, Tabe Y, Konoplev S, Xu Y, Levsath CE, Lu H et al. CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells. Mol Cancer Ther 2008; 7: 48-58.
    • (2008) Mol Cancer Ther , vol.7 , pp. 48-58
    • Jin, L.1    Tabe, Y.2    Konoplev, S.3    Xu, Y.4    Levsath, C.E.5    Lu, H.6
  • 9
    • 70350755790 scopus 로고    scopus 로고
    • Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dosedependent manner resulting in increased susceptibility of BCR-ABL\+ cell to Imatinib and Nilotinib
    • Dillmann F, Veldwijk MR, Laufs S, Sperandio M, Calandra G, Wenz F et al. Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dosedependent manner resulting in increased susceptibility of BCR-ABL\+ cell to Imatinib and Nilotinib. Leuk Lymphoma 2009; 50: 1676-1686.
    • (2009) Leuk Lymphoma , vol.50 , pp. 1676-1686
    • Dillmann, F.1    Veldwijk, M.R.2    Laufs, S.3    Sperandio, M.4    Calandra, G.5    Wenz, F.6
  • 10
    • 33745198035 scopus 로고    scopus 로고
    • Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations
    • Giuntoli S, Rovida E, Barbetti V, Cipolleschi MG, Olivotto M, Dello Sbarba P. Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations. Leukemia 2006; 20: 1291-1293.
    • (2006) Leukemia , vol.20 , pp. 1291-1293
    • Giuntoli, S.1    Rovida, E.2    Barbetti, V.3    Cipolleschi, M.G.4    Olivotto, M.5    Dello Sbarba, P.6
  • 11
    • 84863338358 scopus 로고    scopus 로고
    • HIF1a is required for survival maintenance of chronic myeloid leukemia stem cells
    • Zhang H, Li H, Xi HS, Li S. HIF1a is required for survival maintenance of chronic myeloid leukemia stem cells. Blood 2012b; 119: 2595-2607.
    • (2012) Blood , vol.119 , pp. 2595-2607
    • Zhang, H.1    Li, H.2    Xi, H.S.3    Li, S.4
  • 12
    • 33846254013 scopus 로고    scopus 로고
    • Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias
    • Zeng Z, Samudio IJ, Munsell M, An J, Huang Z, Estey E et al. Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias. Mol Cancer Ther 2006; 5: 3113-3121.
    • (2006) Mol Cancer Ther , vol.5 , pp. 3113-3121
    • Zeng, Z.1    Samudio, I.J.2    Munsell, M.3    An, J.4    Huang, Z.5    Estey, E.6
  • 13
    • 84860767803 scopus 로고    scopus 로고
    • Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib
    • Weisberg E, Azab AK, Manley PW, Kung AL, Christie AL, Bronson R et al. Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib. Leukemia 2012; 26: 985-990.
    • (2012) Leukemia , vol.26 , pp. 985-990
    • Weisberg, E.1    Azab, A.K.2    Manley, P.W.3    Kung, A.L.4    Christie, A.L.5    Bronson, R.6
  • 14
    • 66149150580 scopus 로고    scopus 로고
    • CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
    • Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X et al. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood 2009; 113: 4341-4351.
    • (2009) Blood , vol.113 , pp. 4341-4351
    • Azab, A.K.1    Runnels, J.M.2    Pitsillides, C.3    Moreau, A.S.4    Azab, F.5    Leleu, X.6
  • 15
    • 84862506605 scopus 로고    scopus 로고
    • Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
    • Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R et al. Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features. Blood 2012; 119: 5782-5794.
    • (2012) Blood , vol.119 , pp. 5782-5794
    • Azab, A.K.1    Hu, J.2    Quang, P.3    Azab, F.4    Pitsillides, C.5    Awwad, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.