Prognostic value of resting-state electroencephalography structure in disentangling vegetative and minimally conscious states: A preliminary study

Neurorehabilitation and Neural Repair

Volumn 27, Issue 4, 2013, Pages 345-354

  Fingelkurts, Andrew A ^a   Fingelkurts, Alexander A ^a   Bagnato, Sergio ^b   Boccagni, Cristina ^b   Galardi, Giuseppe ^b  

^a BM Science   (Finland)

^b Fondazione Istituto San Raffaele G Giglio   (Italy)

Author keywords

brain damage; brain synchrony; EEG; functional connectivity; minimally conscious state; vegetative state

Indexed keywords

ACTION POTENTIAL; ADOLESCENT; ADULT; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN FUNCTION; CLINICAL ARTICLE; CONSCIOUSNESS; CONSCIOUSNESS DISORDER; ELECTROENCEPHALOGRAPHY; FEMALE; HUMAN; MALE; PARALYSIS; PATIENT ASSESSMENT; PROGNOSIS; REST;

ADOLESCENT; ADULT; AGED; CEREBRAL CORTEX; COHORT STUDIES; CONSCIOUSNESS; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; MIDDLE AGED; PERSISTENT VEGETATIVE STATE; PILOT PROJECTS; PROGNOSIS; TIME FACTORS; YOUNG ADULT;

EID: 84876141061     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968312469836     Document Type: Article

References (41)

1. The vegetative state: guidance on diagnosis and management. A report of a working party of the Royal College of Physicians. Clin Med. 2003 ; 2: 249-254
2. Monti MM, Laureys S, Owen AM. The vegetative state. BMJ. 2010 ; 341: c3765
3. Nagel T. What is it like to be a bat?. Philos Rev. 1974 ; 83: 435-450
4. Braakman R, Jennett WB, Minderhoud JM. Prognosis of the posttraumatic vegetative state. Acta Neurochir (Wien). 1988 ; 95: 49-52
5. Medical aspects of the persistent vegetative state (2). N Engl J Med. 1994 ; 330: 1572-1579
6. Giacino JT, Ashwal S, Childs N, et al. The minimally conscious state: definition and diagnostic criteria. Neurology. 2002 ; 58: 349-353
7. Di H, Boly M, Weng X, Ledoux D, Laureys S. Neuroimaging activation studies in the vegetative state: predictors of recovery?. Clin Med. 2008 ; 8: 502-507
8. Laureys S, Boly M. What is it like to be vegetative or minimally conscious?. Curr Opin Neurol. 2007 ; 20: 609-613
9. Andrews K. Medical decision making in the vegetative state: withdrawal of nutrition and hydration. NeuroRehabilitation. 2004 ; 19: 299-304
10. Cruse D, Chennu S, Chatelle C, et al. Bedside detection of awareness in the vegetative state: a cohort study. Lancet. 2011 ; 378: 2088-2094
11. Nunez PL. Toward a quantitative description of large-scale neocortical dynamic function and EEG. Behav Brain Sci. 2000 ; 23: 371-398
12. John ER. The neurophysics of consciousness. Brain Res Brain Res Rev. 2002 ; 39: 1-28
13. Freeman WJ. Evidence from human scalp electroencephalograms of global chaotic itinerancy. Chaos. 2003 ; 13: 1067-1077
14. Kaplan AY, Fingelkurts AA, Fingelkurts AA, Borisov SV, Darkhovsky BS. Nonstationary nature of the brain activity as revealed by EEG/MEG: methodological, practical and conceptual challenges. Signal Process. 2005 ; 85: 2190-2212
15. Fingelkurts AA, Fingelkurts AA Focus on Brain Mapping Research. Chen FJ, ed. New York, NY: Nova Science ; 59-98.
16. Fingelkurts AA, Fingelkurts AA, Neves CFH. Natural world physical, brain operational, and mind phenomenal space-time. Phys Life Rev. 2010 ; 7: 195-249
17. Fingelkurts AA, Fingelkurts AA, Bagnato S, Boccagni C, Galardi G. Toward operational architectonics of consciousness: basic evidence from patients with severe cerebral injuries. Cogn Process. 2012 ; 13: 111-131
18. Moulton RJ Head Injury. Reilly P Bullock R, ed. London, England: Chapman & Hall ; 1997: 229-241.
19. Thakor NV, Jia X, Geocadin RG Quantitative EEG Analysis Methods and Clinical Applications. Tong S Thakor NV, ed. Norwood, MA: Artech House ; 2009: 169-192.
20. Kotchoubey B, Lang S, Mezger G, et al. Information processing in severe disorders of consciousness: vegetative state and minimally conscious state. Clin Neurophysiol. 2005 ; 116: 2441-2453
21. Bagnato S, Boccagni C, Prestandrea C, Sant'Angelo A, Castiglione A, Galardi G. Prognostic value of standard EEG in traumatic and non-traumatic disorders of consciousness following coma. Clin Neurophysiol. 2010 ; 121: 274-280
22. Boccagni C, Bagnato S, Sant'Angelo A, Prestandrea C, Galardi G. Usefulness of standard EEG in predicting the outcome of patients with disorders of consciousness following anoxic coma. J Clin Neurophysiol. 2011 ; 28: 489-492
23. Fingelkurts AA, Fingelkurts AA, Bagnato S, Boccagni C, Galardi G. Life or death: prognostic value of a resting EEG with regards to survival in patients in vegetative and minimally conscious states. PLoS One. 2011 ; 6: e25967
24. Young GB. The EEG in coma. J Clin Neurophysiol. 2000 ; 17: 473-485
25. Wallace BE, Wagner AK, Wagner EP, McDeavitt JT. A history and review of quantitative EEG in traumatic brain injury. J Head Trauma Rehabil. 2001 ; 16: 165-190
26. Lehmann D, Ozaki H, Pal I. EEG alpha map series: brain microstates by space-oriented adaptive segmentation. Electroencephalogr Clin Neurophysiol. 1987 ; 67: 271-288
27. Fingelkurts AA, Fingelkurts AA. Alpha rhythm operational architectonics in the continuum of normal and pathological brain states: current state of research. Int J Psychophysiol. 2010 ; 76: 93-106
28. Fingelkurts AA, Fingelkurts AA. Brain-mind operational architectonics imaging: technical and methodological aspects. Open Neuroimag J. 2008 ; 2: 73-93
29. Fingelkurts AA, Fingelkurts AA, Bagnato S, Boccagni C, Galardi G. EEG oscillatory states as neuro-phenomenology of consciousness as revealed from patients in vegetative and minimally conscious states. Conscious Cogn. 2012 ; 21: 149-169
30. Persistent vegetative state: report of the American Neurological Association Committee on Ethical Affairs. Ann Neurol. 1993 ; 33: 386-390
31. Gouvier WD, Blanton PD, LaPorte KK, Nepomuceno C. Reliability and validity of the Disability Rating Scale and the Levels of Cognitive Functioning Scale in monitoring recovery from severe head injury. Arch Phys Med Rehabil. 1987 ; 68: 94-97
32. Perticoni GF, Pratticchizzo L, Lupo R, Spaccatini A, Brunori P, Tiacci C. High doses of phenobarbital in resistant convulsive epileptic state in childhood. Electroencephalogr Clin Neurophysiol. 1995 ; 95: 51P
33. Clemens B, Piros P, Bessenyei M, Hollydy K. Lamotrigine decreases EEG synchronization in a use-dependent manner in patients with idiopathic generalized epilepsy. Clin Neurophysiol. 2007 ; 118: 910-917
34. Jennett B The Vegetative State: Medical Facts, Ethical and Legal Dilemmas. Cambridge, England: Cambridge University Press ; 2002 :
35. Oransky I. Neurologists say Florida woman is very unlikely to recover. Lancet Neurol. 2003 ; 2: 715
36. Tresch DD, Sims FH, Duthie EH, Goldstein MD, Lane PS. Clinical characteristics of patients in the persistent vegetative state. Arch Intern Med. 1991 ; 151: 930-932
37. Childs NL, Mercer WN, Childs HW. Accuracy of diagnosis of persistent vegetative state. Neurology. 1993 ; 43: 1465-1467
38. Andrews K, Murphy L, Munday R, Littlewood C. Misdiagnosis of the vegetative state: retrospective study in a rehabilitation unit. BMJ. 1996 ; 313: 13-16
39. Schnakers C, Giacino J, Kalmar K, et al. Does the FOUR score correctly diagnose the vegetative and minimally conscious states?. Ann Neurol. 2006 ; 60: 744-745
40. Sarà M, Pistoia F, Pasqualetti P, Sebastiano F, Onorati P, Rossini PM. Functional isolation within the cerebral cortex in the vegetative state: a nonlinear method to predict clinical outcomes. Neurorehabil Neural Repair. 2011 ; 25: 35-42
41. Piccione F, Cavinato M, Manganotti P, et al. Behavioral and neurophysiological effects of repetitive transcranial magnetic stimulation on the minimally conscious state: a case study. Neurorehabil Neural Repair. 2011 ; 25: 98-102