Genetic variations in drug-induced liver injury (DILI): Resolving the puzzle

Frontiers in Genetics

Volumn 3, Issue NOV, 2012, Pages

  Stephens, Camilla ^a,b   Lucena, M Isabel ^a,b   Andrade, Raúl J ^a,b  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84876120471     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2012.00253     Document Type: Article

References (9)

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2. Agundez, J. A. G., Lucena, M. I., Martínez, C., Andrade, R. J., Blanca, M., Ayuso, P., et al. (2011). Assessment of nonsteroidal anti-inflammatory drug-induced hepatotoxicity. Expert Opin. Drug Metab. Toxicol. 7, 817-828.
3. Andrade, R. J., Robles, M., Ulzurrun, E., and Lucena, M. I. (2009). Drug-induced liver injury: insights from genetic studies. Pharmacogenomics 10, 1467-1487.
4. Cordero, P., and Ashley, E. A. (2012). Whole-genome sequencing in personalized therapeutics. Clin. Pharmacol. Ther. 91, 1001-1009.
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7. Lucena, M. I., Andrade, R. J., Martínez, C., Ulzurrun, E., García-Martín, E., Borraz, Y., et al. (2008). Glutathione S-transferase M1 and T1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. Hepatology 48, 588-596.
8. Lucena, M. I., García-Martín, E., Andrade, R. J., Martínez, C., Stephens, C., Ruiz, J. D., et al. (2010). Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury. Hepatology 52, 303-312.
9. Wang, K., Li, M., and Hakonarson, H. (2010). Analysing biological pathways in genome-wide association studies. Nat. Rev. Genet. 11, 843-854.