Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70)

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 9, 2013, Pages 2679-2682

  Chen, Duo Zhi ^a,b,c   Jiang, Jian Dong ^d   Zhang, Ke Qing ^c   He, Hong Ping ^a   Di, Ying Tong ^a   Zhang, Yu ^a   Cai, Jie Yun ^a,b   Wang, Lei ^a,b   Li, Shun Lin ^a   Yi, Ping ^e   Peng, Zong Gen ^d   Hao, Xiao Jiang ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c YUNNAN UNIVERSITY   (China)

^d INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^e HONGHE UNIVERSITY   (China)

Author keywords

(+) Lycoricidine; Anti HCV activity; Down regulators; Heat stress cognate 70 (Hsc70); Structure activity relationship (SAR)

Indexed keywords

ANTIVIRUS AGENT; HEAT SHOCK COGNATE PROTEIN 70; LYCORICIDINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; HEPATITIS C VIRUS; PROTEIN EXPRESSION; PROTEIN TARGETING; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION;

AMARYLLIDACEAE ALKALOIDS; ANTIVIRAL AGENTS; CELL LINE; GENE EXPRESSION; HEPACIVIRUS; HSC70 HEAT-SHOCK PROTEINS; HUMANS; PHENANTHRIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

HEPATITIS C VIRUS;

EID: 84876117630     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.02.089     Document Type: Article

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