-
1
-
-
80053644416
-
In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells
-
R. Rossi, M. Lichtner, A. De Rosa, I. Sauzullo, F. Mengoni, A.P. Massetti, C.M. Mastroianni, and V. Vullo In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells Clin. Exp. Immunol. 166 2011 184 190
-
(2011)
Clin. Exp. Immunol.
, vol.166
, pp. 184-190
-
-
Rossi, R.1
Lichtner, M.2
De Rosa, A.3
Sauzullo, I.4
Mengoni, F.5
Massetti, A.P.6
Mastroianni, C.M.7
Vullo, V.8
-
2
-
-
4444246007
-
Chemokine receptor CCR5: Insights into structure, function, and regulation
-
DOI 10.1016/j.cellsig.2004.04.007, PII S0898656804000786
-
M. Oppermann Chemokine receptor CCR5: insights into structure, function, and regulation Cell. Signal. 16 2004 1201 1210 (Pubitemid 39165449)
-
(2004)
Cellular Signalling
, vol.16
, Issue.11
, pp. 1201-1210
-
-
Oppermann, M.1
-
3
-
-
0035815694
-
The BBXB Motif of RANTES Is the Principal Site for Heparin Binding and Controls Receptor Selectivity
-
DOI 10.1074/jbc.M010867200
-
A.E. Proudfoot, S. Fritchley, F. Borlat, J.P. Shaw, F. Vilbois, C. Zwahlen, A. Trkola, D. Marchant, P.R. Clapham, and T.N. Wells The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity J. Biol. Chem. 276 2001 10620 10626 (Pubitemid 38089230)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.14
, pp. 10620-10626
-
-
Proudfoot, A.E.I.1
Fritchley, S.2
Borlat, F.3
Shaw, J.P.4
Vilbois, F.5
Zwahlen, C.6
Trkola, A.7
Marchant, D.8
Clapham, P.R.9
Wells, T.N.C.10
-
4
-
-
0030035550
-
Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1β, and MIP-1α
-
DOI 10.1074/jbc.271.29.17161
-
C.J. Raport, J. Gosling, V.L. Schweickart, P.W. Gray, and I.F. Charo Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha J. Biol. Chem. 271 1996 17161 17166 (Pubitemid 26244268)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.29
, pp. 17161-17166
-
-
Raport, C.J.1
Gosling, J.2
Schweickart, V.L.3
Gray, P.W.4
Charo, I.F.5
-
5
-
-
0034939225
-
Diverging binding capacities of natural LD78β isoforms of macrophage inflammatory protein-1α to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils
-
DOI 10.1002/1521-4141(200107)31:7<2170::AID-IMMU2170>3.0.CO;2-D
-
S. Struyf, P. Menten, J.P. Lenaerts, W. Put, A. D'Haese, E. De Clercq, D. Schols, P. Proost, and J. Van Damme Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils Eur. J. Immunol. 31 2001 2170 2178 (Pubitemid 32640734)
-
(2001)
European Journal of Immunology
, vol.31
, Issue.7
, pp. 2170-2178
-
-
Struyf, S.1
Menten, P.2
Lenaerts, J.-P.3
Put, W.4
D'Haese, A.5
De Clercq, E.6
Schols, D.7
Proost, P.8
Van Damme, J.9
-
6
-
-
15844389650
-
+ cells is mediated by the chemokine receptor CC-CKR-5
-
DOI 10.1038/381667a0
-
+ cells is mediated by the chemokine receptor CC-CKR-5 Nature 381 1996 667 673 (Pubitemid 26197680)
-
(1996)
Nature
, vol.381
, Issue.6584
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
Martin, S.R.4
Huang, Y.5
Nagashima, K.A.6
Cayanan, C.7
Maddon, P.J.8
Koup, R.A.9
Moore, J.P.10
Paxton, W.A.11
-
7
-
-
84865652575
-
Use of (alternative) coreceptors for HIV entry
-
G. Pollakis, and W.A. Paxton Use of (alternative) coreceptors for HIV entry Curr. Opin. HIV AIDS 7 2012 440 449
-
(2012)
Curr. Opin. HIV AIDS
, vol.7
, pp. 440-449
-
-
Pollakis, G.1
Paxton, W.A.2
-
8
-
-
1842431907
-
Induction of Autoantibodies to CCR5 in Macaques and Subsequent Effects Upon Challenge with An R5-Tropic Simian/Human Immunodeficiency Virus
-
DOI 10.1128/JVI.78.8.4037-4047.2004
-
B. Chackerian, L. Briglio, P.S. Albert, D.R. Lowy, and J.T. Schiller Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus J. Virol. 78 2004 4037 4047 (Pubitemid 38437210)
-
(2004)
Journal of Virology
, vol.78
, Issue.8
, pp. 4037-4047
-
-
Chackerian, B.1
Briglio, L.2
Albert, P.S.3
Lowy, D.R.4
Schiller, J.T.5
-
9
-
-
22544456536
-
Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals
-
DOI 10.1086/431519
-
Z.L. Brumme, J. Goodrich, H.B. Mayer, C.J. Brumme, B.M. Henrick, B. Wynhoven, J.J. Asselin, P.K. Cheung, R.S. Hogg, J.S. Montaner, and P.R. Harrigan Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals J. Infect. Dis. 192 2005 466 474 (Pubitemid 41023125)
-
(2005)
Journal of Infectious Diseases
, vol.192
, Issue.3
, pp. 466-474
-
-
Brumme, Z.L.1
Goodrich, J.2
Mayer, H.B.3
Brumme, C.J.4
Henrick, B.M.5
Wynhoven, B.6
Asselin, J.J.7
Cheung, P.K.8
Hogg, R.S.9
Montaner, J.S.G.10
Harrigan, P.R.11
-
10
-
-
14844333093
-
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection
-
DOI 10.1086/428096
-
G.J. Moyle, A. Wildfire, S. Mandalia, H. Mayer, J. Goodrich, J. Whitcomb, and B.G. Gazzard Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection J. Infect. Dis. 191 2005 866 872 (Pubitemid 40349800)
-
(2005)
Journal of Infectious Diseases
, vol.191
, Issue.6
, pp. 866-872
-
-
Moyle, G.J.1
Wildfire, A.2
Mandalia, S.3
Mayer, H.4
Goodrich, J.5
Whitcomb, J.6
Gazzard, B.G.7
-
11
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia growth and development study, multicenter AIDS cohort study, multicenter hemophilia cohort study, San Francisco City Cohort, ALIVE study
-
M. Dean, M. Carrington, C. Winkler, G.A. Huttley, M.W. Smith, R. Allikmets, J.J. Goedert, S.P. Buchbinder, E. Vittinghoff, E. Gomperts, S. Donfield, D. Vlahov, R. Kaslow, A. Saah, C. Rinaldo, R. Detels, and S.J. O'Brien Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia growth and development study, multicenter AIDS cohort study, multicenter hemophilia cohort study, San Francisco City Cohort, ALIVE study Science 273 1996 1856 1862
-
(1996)
Science
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
Huttley, G.A.4
Smith, M.W.5
Allikmets, R.6
Goedert, J.J.7
Buchbinder, S.P.8
Vittinghoff, E.9
Gomperts, E.10
Donfield, S.11
Vlahov, D.12
Kaslow, R.13
Saah, A.14
Rinaldo, C.15
Detels, R.16
O'Brien, S.J.17
-
12
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
DOI 10.1038/nm1196-1240
-
Y. Huang, W.A. Paxton, S.M. Wolinsky, A.U. Neumann, L. Zhang, T. He, S. Kang, D. Ceradini, Z. Jin, K. Yazdanbakhsh, K. Kunstman, D. Erickson, E. Dragon, N.R. Landau, J. Phair, D.D. Ho, and R.A. Koup The role of a mutant CCR5 allele in HIV-1 transmission and disease progression Nat. Med. 2 1996 1240 1243 (Pubitemid 26375409)
-
(1996)
Nature Medicine
, vol.2
, Issue.11
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
Neumann, A.U.4
Zhang, L.5
He, T.6
Kang, S.7
Ceradini, D.8
Jin, Z.9
Yazdanbakhsh, K.10
Kunstman, K.11
Erickson, D.12
Dragon, E.13
Landau, N.R.14
Phair, J.15
Ho, D.D.16
Koup, R.A.17
-
13
-
-
73549092165
-
Entry inhibitors in the treatment of HIV-1 infection
-
J.C. Tilton, and R.W. Doms Entry inhibitors in the treatment of HIV-1 infection Antiviral Res. 85 2010 91 100
-
(2010)
Antiviral Res.
, vol.85
, pp. 91-100
-
-
Tilton, J.C.1
Doms, R.W.2
-
15
-
-
84864658614
-
Update on clinical and methodological recommendations for genotypic determination of HIV tropism to guide the usage of CCR5 antagonists
-
E. Poveda, R. Paredes, S. Moreno, J. Alcami, J. Cordoba, R. Delgado, F. Gutierrez, J.M. Llibre, M. Garcia Deltoro, J. Hernandez-Quero, F. Pulido, J.A. Iribarren, and F. Garcia Update on clinical and methodological recommendations for genotypic determination of HIV tropism to guide the usage of CCR5 antagonists AIDS Rev. 14 2012 208 217
-
(2012)
AIDS Rev.
, vol.14
, pp. 208-217
-
-
Poveda, E.1
Paredes, R.2
Moreno, S.3
Alcami, J.4
Cordoba, J.5
Delgado, R.6
Gutierrez, F.7
Llibre, J.M.8
Garcia Deltoro, M.9
Hernandez-Quero, J.10
Pulido, F.11
Iribarren, J.A.12
Garcia, F.13
-
16
-
-
44049089377
-
New approaches in the treatment of HIV/AIDS - Focus on maraviroc and other CCR5 antagonists
-
H.P. Schlecht, S. Schellhorn, B.J. Dezube, and J.M. Jacobson New approaches in the treatment of HIV/AIDS - focus on maraviroc and other CCR5 antagonists Ther. Clin. Risk Manage. 4 2008 473 485 (Pubitemid 351712006)
-
(2008)
Therapeutics and Clinical Risk Management
, vol.4
, Issue.2
, pp. 473-485
-
-
Schlecht, H.P.1
Schellhorn, S.2
Dezube, B.J.3
Jacobson, J.M.4
-
17
-
-
33748041977
-
Construction, purification, and immunogenicity of recombinant cystein-cystein type chemokine receptor 5 vaccine
-
DOI 10.1016/j.pep.2006.02.020, PII S1046592806000726
-
K. Wu, X. Xue, Z. Wang, Z. Yan, J. Shi, W. Han, and Y. Zhang Construction, purification, and immunogenicity of recombinant cystein-cystein type chemokine receptor 5 vaccine Protein Expr. Purif. 49 2006 108 113 (Pubitemid 44294766)
-
(2006)
Protein Expression and Purification
, vol.49
, Issue.1
, pp. 108-113
-
-
Wu, K.1
Xue, X.2
Wang, Z.3
Yan, Z.4
Shi, J.5
Han, W.6
Zhang, Y.7
-
18
-
-
20444412384
-
Production and purification of recombinant human BLyS mutant from inclusion bodies
-
DOI 10.1016/j.pep.2005.03.032, PII S104659280500121X
-
X. Xue, Z. Wang, Z. Yan, J. Shi, W. Han, and Y. Zhang Production and purification of recombinant human BLyS mutant from inclusion bodies Protein Expr. Purif. 42 2005 194 199 (Pubitemid 40793411)
-
(2005)
Protein Expression and Purification
, vol.42
, Issue.1
, pp. 194-199
-
-
Xue, X.1
Wang, Z.2
Yan, Z.3
Shi, J.4
Han, W.5
Zhang, Y.6
-
19
-
-
0042855800
-
Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120
-
DOI 10.1016/S0092-8674(03)00508-7
-
H. Choe, W. Li, P.L. Wright, N. Vasilieva, M. Venturi, C.C. Huang, C. Grundner, T. Dorfman, M.B. Zwick, L. Wang, E.S. Rosenberg, P.D. Kwong, D.R. Burton, J.E. Robinson, J.G. Sodroski, and M. Farzan Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120 Cell 114 2003 161 170 (Pubitemid 36936910)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 161-170
-
-
Choe, H.1
Li, W.2
Wright, P.L.3
Vasilieva, N.4
Venturi, M.5
Huang, C.-C.6
Grundner, C.7
Dorfman, T.8
Zwick, M.B.9
Wang, L.10
Rosenberg, E.S.11
Kwong, P.D.12
Burton, D.R.13
Robinson, J.E.14
Sodroski, J.G.15
Farzan, M.16
-
20
-
-
0033383722
-
Adaptation to promiscuous usage of chemokine receptors is not a prerequisite for human immunodeficiency virus type 1 disease progression
-
DOI 10.1086/314987
-
A.M. de Roda Husman, R.P. van Rij, H. Blaak, S. Broersen, and H. Schuitemaker Adaptation to promiscuous usage of chemokine receptors is not a prerequisite for human immunodeficiency virus type 1 disease progression J. Infect. Dis. 180 1999 1106 1115 (Pubitemid 30070193)
-
(1999)
Journal of Infectious Diseases
, vol.180
, Issue.4
, pp. 1106-1115
-
-
De Roda Husman, A.-M.1
Van Rij, R.P.2
Blaak, H.3
Broersen, S.4
Schuitemaker, H.5
-
21
-
-
77951157311
-
CCR5 antagonists: Host-targeted antiviral agents for the treatment of HIV infection, 4 years on
-
M. Westby, and E. van der Ryst CCR5 antagonists: host-targeted antiviral agents for the treatment of HIV infection, 4 years on Antimicrob. Agents Chemother. 20 2010 179 192
-
(2010)
Antimicrob. Agents Chemother.
, vol.20
, pp. 179-192
-
-
Westby, M.1
Van Der Ryst, E.2
-
22
-
-
34249711352
-
Access denied? The status of co-receptor inhibition to counter HIV entry
-
DOI 10.1517/14656566.8.7.923
-
P. Biswas, G. Tambussi, and A. Lazzarin Access denied? The status of co-receptor inhibition to counter HIV entry Expert Opin. Pharmacother. 8 2007 923 933 (Pubitemid 351227480)
-
(2007)
Expert Opinion on Pharmacotherapy
, vol.8
, Issue.7
, pp. 923-933
-
-
Biswas, P.1
Tambussi, G.2
Lazzarin, A.3
-
23
-
-
77957349209
-
Phase 2a study of the CCR5 monoclonal antibody PRO 140 administered intravenously to HIV-infected adults
-
J.M. Jacobson, J.P. Lalezari, M.A. Thompson, C.J. Fichtenbaum, M.S. Saag, B.S. Zingman, P. D'Ambrosio, N. Stambler, Y. Rotshteyn, A.J. Marozsan, P.J. Maddon, S.A. Morris, and W.C. Olson Phase 2a study of the CCR5 monoclonal antibody PRO 140 administered intravenously to HIV-infected adults Antimicrob. Agents Chemother. 54 2010 4137 4142
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 4137-4142
-
-
Jacobson, J.M.1
Lalezari, J.P.2
Thompson, M.A.3
Fichtenbaum, C.J.4
Saag, M.S.5
Zingman, B.S.6
D'Ambrosio, P.7
Stambler, N.8
Rotshteyn, Y.9
Marozsan, A.J.10
Maddon, P.J.11
Morris, S.A.12
Olson, W.C.13
-
24
-
-
77951916324
-
Anti-HIV-1 activity of weekly or biweekly treatment with subcutaneous PRO 140, a CCR5 monoclonal antibody
-
J.M. Jacobson, M.A. Thompson, J.P. Lalezari, M.S. Saag, B.S. Zingman, P. D'Ambrosio, N. Stambler, Y. Rotshteyn, A.J. Marozsan, P.J. Maddon, S.A. Morris, and W.C. Olson Anti-HIV-1 activity of weekly or biweekly treatment with subcutaneous PRO 140, a CCR5 monoclonal antibody J. Infect. Dis. 201 2010 1481 1487
-
(2010)
J. Infect. Dis.
, vol.201
, pp. 1481-1487
-
-
Jacobson, J.M.1
Thompson, M.A.2
Lalezari, J.P.3
Saag, M.S.4
Zingman, B.S.5
D'Ambrosio, P.6
Stambler, N.7
Rotshteyn, Y.8
Marozsan, A.J.9
Maddon, P.J.10
Morris, S.A.11
Olson, W.C.12
-
25
-
-
84922392690
-
Monoclonal CCR5 antibody for treatment of people with HIV infection
-
L. Li, T. Sun, K. Yang, P. Zhang, W.Q. Jia, Monoclonal CCR5 antibody for treatment of people with HIV infection, Cochrane Database Syst. Rev. (2010) CD008439.
-
(2010)
Cochrane Database Syst. Rev.
-
-
Li, L.1
Sun, T.2
Yang, K.3
Zhang, P.4
Jia, W.Q.5
-
26
-
-
84865985400
-
Vicriviroc plus optimized background therapy for treatment-experienced subjects with CCR5 HIV-1 infection: Final results of two randomized phase III trials
-
M.M. Caseiro, M. Nelson, R.S. Diaz, J. Gathe, J.L. de Andrade Neto, J. Slim, A. Solano, E.M. Netto, C. Mak, J. Shen, W. Greaves, L.M. Dunkle, R.A. Vilchez, and J. Zeinecker Vicriviroc plus optimized background therapy for treatment-experienced subjects with CCR5 HIV-1 infection: final results of two randomized phase III trials J. Infect. 65 2012 326 335
-
(2012)
J. Infect.
, vol.65
, pp. 326-335
-
-
Caseiro, M.M.1
Nelson, M.2
Diaz, R.S.3
Gathe, J.4
De Andrade Neto, J.L.5
Slim, J.6
Solano, A.7
Netto, E.M.8
Mak, C.9
Shen, J.10
Greaves, W.11
Dunkle, L.M.12
Vilchez, R.A.13
Zeinecker, J.14
-
27
-
-
84865163658
-
Detection of HIV-1 CXCR4 tropism and resistance in treatment experienced subjects receiving CCR5 antagonist-Vicriviroc
-
P. McNicholas, R.A. Vilchez, W. Greaves, S. Kumar, C. Onyebuchi, T. Black, and J.M. Strizki Detection of HIV-1 CXCR4 tropism and resistance in treatment experienced subjects receiving CCR5 antagonist-Vicriviroc J. Clin. Virol. 55 2012 134 139
-
(2012)
J. Clin. Virol.
, vol.55
, pp. 134-139
-
-
McNicholas, P.1
Vilchez, R.A.2
Greaves, W.3
Kumar, S.4
Onyebuchi, C.5
Black, T.6
Strizki, J.M.7
-
28
-
-
84863995591
-
Stochastic model of in-vivo X4 emergence during HIV infection: Implications for the CCR5 inhibitor maraviroc
-
B. Savkovic, G. Symonds, and J.M. Murray Stochastic model of in-vivo X4 emergence during HIV infection: implications for the CCR5 inhibitor maraviroc PloS One 7 2012 e38755
-
(2012)
PloS One
, vol.7
, pp. 38755
-
-
Savkovic, B.1
Symonds, G.2
Murray, J.M.3
|