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Volumn 106, Issue 3, 2013, Pages 333-340

Dose-escaltion in head and neck cancer A dose escalation study with intensity modulated radiation therapy (IMRT) in T2N0, T2N1, T3N0 squamous cell carcinomas (SCC) of the oropharynx, larynx and hypopharynx using a simultaneous integrated boost (SIB) approach

Author keywords

Head and neck carcinoma IMRT Simultaneous integrated boost Dose escalation

Indexed keywords

ADULT; ARTICLE; CANCER CONTROL; CANCER LOCALIZATION; CANCER PATIENT; CANCER PREVENTION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DISEASE SEVERITY; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HUMAN; HYPOPHARYNX CARCINOMA; HYPOPHARYNX SQUAMOUS CELL CARCINOMA; INTENSITY MODULATED RADIATION THERAPY; LARYNX SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; MULTICENTER STUDY; OROPHARYNX CARCINOMA; OROPHARYNX SQUAMOUS CELL CARCINOMA; OVERALL SURVIVAL; PATIENT SAFETY; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PLANNING TARGET VOLUME; PRIORITY JOURNAL; RADIATION DERMATITIS; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIATION DOSE ESCALATION; RADIATION DOSE FRACTIONATION; RADIATION HAZARD; SIMULTANEOUS INTEGRATED BOOST TECHNIQUE; SQUAMOUS CELL CARCINOMA; TREATMENT DURATION; TREATMENT OUTCOME; CANCER STAGING; HYPOPHARYNX TUMOR; LARYNX TUMOR; METHODOLOGY; MIDDLE AGED; OROPHARYNX TUMOR; PATHOLOGY;

EID: 84876100268     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.03.002     Document Type: Article
Times cited : (75)

References (34)
  • 1
    • 84861092133 scopus 로고    scopus 로고
    • Distant metastases in head-and-neck squamous cell carcinoma treated with intensity-modulated radiotherapy
    • M. Yao, M. Lu, and P. Savvides Distant metastases in head-and-neck squamous cell carcinoma treated with intensity-modulated radiotherapy Int J Radiat Oncol Biol Phys 83 2012 684 689
    • (2012) Int J Radiat Oncol Biol Phys , vol.83 , pp. 684-689
    • Yao, M.1    Lu, M.2    Savvides, P.3
  • 3
    • 33747881607 scopus 로고    scopus 로고
    • Hyperfractionated or accelerated radiotherapy in head and neck cancer: A meta-analysis
    • J. Bourhis, J. Overgaard, and H. Audry Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis Lancet 368 2006 843 854
    • (2006) Lancet , vol.368 , pp. 843-854
    • Bourhis, J.1    Overgaard, J.2    Audry, H.3
  • 4
    • 18544409287 scopus 로고    scopus 로고
    • A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003
    • K.K. Fu, T.F. Pajak, and A. Trotti A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003 Int J Radiat Oncol Biol Phys 48 2000 7 16
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 7-16
    • Fu, K.K.1    Pajak, T.F.2    Trotti, A.3
  • 5
    • 20244364373 scopus 로고
    • Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy
    • J.C. Horiot, R. LeFur, and T. N'Guyen Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy Radiother Oncol 25 1992 231 241
    • (1992) Radiother Oncol , vol.25 , pp. 231-241
    • Horiot, J.C.1    Lefur, R.2    N'Guyen, T.3
  • 6
    • 0030842059 scopus 로고    scopus 로고
    • Accelerated fractionation compared to conventional fractionation improves locoregional control in the radiotherapy of advanced head and neck cancer: Results of the EORTC 22581 randomized trial
    • J.C. Horiot, P. Bontemps, and W. Van Den Bogaert Accelerated fractionation compared to conventional fractionation improves locoregional control in the radiotherapy of advanced head and neck cancer: results of the EORTC 22581 randomized trial Radiother Oncol 44 1997 111 121
    • (1997) Radiother Oncol , vol.44 , pp. 111-121
    • Horiot, J.C.1    Bontemps, P.2    Van Den Bogaert, W.3
  • 7
    • 0141540770 scopus 로고    scopus 로고
    • Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6&7 randomised controlled trial
    • J. Overgaard, H.S. Hansen, and L. Specht Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6&7 randomised controlled trial Lancet 362 2003 933 940
    • (2003) Lancet , vol.362 , pp. 933-940
    • Overgaard, J.1    Hansen, H.S.2    Specht, L.3
  • 8
    • 33745524904 scopus 로고    scopus 로고
    • Phase III randomized trial of very accelerated radiation therapy compared with conventional radiation therapy in squamous cell head and neck cancer: A GORTEC trial
    • J. Bourhis, M. Lapeyre, and J. Tortochaux Phase III randomized trial of very accelerated radiation therapy compared with conventional radiation therapy in squamous cell head and neck cancer: a GORTEC trial J Clin Oncol 24 2006 2873 2878
    • (2006) J Clin Oncol , vol.24 , pp. 2873-2878
    • Bourhis, J.1    Lapeyre, M.2    Tortochaux, J.3
  • 9
    • 0032790945 scopus 로고    scopus 로고
    • Smart (simultaneous modulated accelerated radiation therapy) boost: A new accelerated fractionation schedule for the treatment of head and neck cancer with intensity modulated radiotherapy
    • E.B. Butler, B.S. Teh, and W.H. Grant Smart (simultaneous modulated accelerated radiation therapy) boost: a new accelerated fractionation schedule for the treatment of head and neck cancer with intensity modulated radiotherapy Int J Radiat Oncol Biol Phys 45 1999 21 32
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 21-32
    • Butler, E.B.1    Teh, B.S.2    Grant, W.H.3
  • 10
    • 0033955922 scopus 로고    scopus 로고
    • Radiobiological considerations in the design of fractionation strategies fir intensity-modulated radiation therapy of head and neck cancers
    • R. Mohan, Q. Wu, M. Manning, and R. Schmidt-Ullrich Radiobiological considerations in the design of fractionation strategies fir intensity-modulated radiation therapy of head and neck cancers Int J Radiat Oncol Biol Phys 46 2000 619 630
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 619-630
    • Mohan, R.1    Wu, Q.2    Manning, M.3    Schmidt-Ullrich, R.4
  • 11
    • 0003575141 scopus 로고    scopus 로고
    • National Cancer Institute Accessed August 2012
    • National Cancer Institute. Common toxicity criteria (CTC) v2.0. Available from: http://ctep.cancer.gov/protocolDevelopment/electronic-applications/ctc. htm. Accessed August 2012.
    • Common Toxicity Criteria (CTC) v2.0
  • 12
    • 84871465395 scopus 로고    scopus 로고
    • RTOG Accessed August 2012
    • RTOG. RTOG/EORTC late radiation morbidity scoring schema. Available from: http://www.rtog.org/ResearchAssociates/AdverseEventReporting/ RTOGEORTCLateRadiationMorbidityScoringSchema.aspx. Accessed August 2012.
    • RTOG/EORTC Late Radiation Morbidity Scoring Schema
  • 13
    • 84864066709 scopus 로고    scopus 로고
    • National Cancer Institute Accessed August 2012
    • National Cancer Institute. Common terminology criteria for adverse events (CTCAE) v4.0. Available from: http://ctep.cancer.gov/protocolDevelopment/ electronic-applications/ctc.htm. Accessed August 2012.
    • Common Terminology Criteria for Adverse Events (CTCAE) v4.0
  • 14
    • 0037677266 scopus 로고    scopus 로고
    • Quality assurance program for intensity-modulated radiotherapy (IMRT) treatments of head and neck carcinomas
    • S. Marcié, P. Aletti, D. Lefkopoulos, and M. Tomsej Quality assurance program for intensity-modulated radiotherapy (IMRT) treatments of head and neck carcinomas Cancer Radiother 7 2003 172 178
    • (2003) Cancer Radiother , vol.7 , pp. 172-178
    • Marcié, S.1    Aletti, P.2    Lefkopoulos, D.3    Tomsej, M.4
  • 15
    • 0342588064 scopus 로고    scopus 로고
    • Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy. Proposal for standardizing terminology and procedure based on the surgical experience
    • V. Gregoire, E. Coche, and G. Cosnard Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy. Proposal for standardizing terminology and procedure based on the surgical experience Radiother Oncol 56 2000 135 150
    • (2000) Radiother Oncol , vol.56 , pp. 135-150
    • Gregoire, V.1    Coche, E.2    Cosnard, G.3
  • 16
    • 33646197680 scopus 로고    scopus 로고
    • Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck
    • V. Gregoire, A. Eisbruch, and M. Hamoir Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck Radiother Oncol 79 2006 15 20
    • (2006) Radiother Oncol , vol.79 , pp. 15-20
    • Gregoire, V.1    Eisbruch, A.2    Hamoir, M.3
  • 18
    • 0003418877 scopus 로고    scopus 로고
    • Prescribing, recording and reporting photon beam therapy (supplement to ICRU report 50)
    • report 62
    • Prescribing, recording and reporting photon beam therapy (supplement to ICRU report 50). International Commission on Radiation Units and Measurements, report 62, 1999.
    • (1999) International Commission on Radiation Units and Measurements
  • 19
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • R. Simon Optimal two-stage designs for phase II clinical trials Control Clin Trials 10 1989 1 10
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 20
    • 0034681783 scopus 로고    scopus 로고
    • Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data. MACH-NC collaborative group. meta-analysis of chemotherapy on head and neck cancer
    • J.P. Pignon, J. Bourhis, C. Domenge, and L. Designé Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC collaborative group. meta-analysis of chemotherapy on head and neck cancer Lancet 355 2000 949 955
    • (2000) Lancet , vol.355 , pp. 949-955
    • Pignon, J.P.1    Bourhis, J.2    Domenge, C.3    Designé, L.4
  • 21
    • 66949128922 scopus 로고    scopus 로고
    • MACH-NC collaborative group. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients
    • J.P. Pignon, A. le Maître, E. Maillard, and J. Bourhis MACH-NC collaborative group. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients Radiother Oncol 92 2009 4 14
    • (2009) Radiother Oncol , vol.92 , pp. 4-14
    • Pignon, J.P.1    Le Maître, A.2    Maillard, E.3    Bourhis, J.4
  • 22
    • 80051789292 scopus 로고    scopus 로고
    • Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): A comprehensive analysis by tumour site: MACH-CH collaborative group
    • P. Blanchard, B. Baujat, and V. Holostenco Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site: MACH-CH collaborative group Radiother Oncol 100 2011 33 40
    • (2011) Radiother Oncol , vol.100 , pp. 33-40
    • Blanchard, P.1    Baujat, B.2    Holostenco, V.3
  • 23
    • 84856485375 scopus 로고    scopus 로고
    • Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): An open-label phase 3 randomised trial
    • J. Bourhis, C. Sire, and P. Graff Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial Lancet Oncol 13 2012 145 153
    • (2012) Lancet Oncol , vol.13 , pp. 145-153
    • Bourhis, J.1    Sire, C.2    Graff, P.3
  • 24
    • 0026023992 scopus 로고
    • Hypofractionation: Lessons from complications
    • G.H. Fletcher Hypofractionation: lessons from complications Radiother Oncol 20 1991 10 15
    • (1991) Radiother Oncol , vol.20 , pp. 10-15
    • Fletcher, G.H.1
  • 25
    • 84859730424 scopus 로고    scopus 로고
    • Prevalence and peak incidence of acute and late normal tissue morbidity in the DAHANCA 6&7 randomised trial with accelerated radiotherapy for head and neck cancer
    • H.R. Mortensen, J. Overgaard, and L. Specht Prevalence and peak incidence of acute and late normal tissue morbidity in the DAHANCA 6&7 randomised trial with accelerated radiotherapy for head and neck cancer Radiother Oncol 103 2012 69 75
    • (2012) Radiother Oncol , vol.103 , pp. 69-75
    • Mortensen, H.R.1    Overgaard, J.2    Specht, L.3
  • 26
    • 0038399940 scopus 로고    scopus 로고
    • Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radioherapy with or without chemotherapy: A systematic literature review
    • A. Trotti, L.A. Bellm, and J.B. Epstein Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radioherapy with or without chemotherapy: a systematic literature review Radiother Oncol 66 2003 253 262
    • (2003) Radiother Oncol , vol.66 , pp. 253-262
    • Trotti, A.1    Bellm, L.A.2    Epstein, J.B.3
  • 27
    • 0031925723 scopus 로고    scopus 로고
    • Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: A randomized multicenter study
    • T.G. Wendt, G.G. Grabenbauer, C.M. Rödel, H.J. Thiel, H. Aydin, and R. Rohloff Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study J Clin Oncol 16 1998 1318 1324
    • (1998) J Clin Oncol , vol.16 , pp. 1318-1324
    • Wendt, T.G.1    Grabenbauer, G.G.2    Rödel, C.M.3    Thiel, H.J.4    Aydin, H.5    Rohloff, R.6
  • 28
    • 4544316285 scopus 로고    scopus 로고
    • Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas: II - Clinical results
    • A. Lauve, M. Morris, and R. Schmidt-Ullrich Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas: II - clinical results Int J Radiat Oncol Biol Phys 60 2004 374 387
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 374-387
    • Lauve, A.1    Morris, M.2    Schmidt-Ullrich, R.3
  • 29
    • 49049115379 scopus 로고    scopus 로고
    • Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: An RTOG analysis
    • M. Machtay, J. Moughan, and A. Trotti Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis J Clin Oncol 26 2008 3582 3589
    • (2008) J Clin Oncol , vol.26 , pp. 3582-3589
    • MacHtay, M.1    Moughan, J.2    Trotti, A.3
  • 30
    • 0037216707 scopus 로고    scopus 로고
    • Late toxicity results of the GORTEC 94-01 randomized trial comparing radiotherapy with concomitant radiochemotherapy for advanced-stage oropharynx carcinoma: Comparison of LENT/SOMA, RTOG/EORTC, and NCI-CTC scoring systems
    • F. Denis, P. Garaud, and E. Bardet Late toxicity results of the GORTEC 94-01 randomized trial comparing radiotherapy with concomitant radiochemotherapy for advanced-stage oropharynx carcinoma: comparison of LENT/SOMA, RTOG/EORTC, and NCI-CTC scoring systems Int J Radiat Oncol Biol Phys 55 2003 93 98
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 93-98
    • Denis, F.1    Garaud, P.2    Bardet, E.3
  • 31
    • 84865782352 scopus 로고    scopus 로고
    • Predictors of severe late radiotherapy related toxicity after hyperfractionated radiotherapy with or without concomitant cisplatin in locally advanced head and neck cancer. Secondary retrospective analysis of a randomized phase III trial (SAKK 10/94)
    • P. Ghadjar, M. Simcock, and F. Zimmermann Predictors of severe late radiotherapy related toxicity after hyperfractionated radiotherapy with or without concomitant cisplatin in locally advanced head and neck cancer. Secondary retrospective analysis of a randomized phase III trial (SAKK 10/94) Radiother Oncol 104 2012 213 218
    • (2012) Radiother Oncol , vol.104 , pp. 213-218
    • Ghadjar, P.1    Simcock, M.2    Zimmermann, F.3
  • 32
    • 77949564251 scopus 로고    scopus 로고
    • Multi-institutional trial of accelerated hypofractionated intensity-modulated radiation therapy for early-stage oropharyngeal cancer (RTOG 00-22)
    • E. Eisbruch, J. Harris, and A.S. Garden Multi-institutional trial of accelerated hypofractionated intensity-modulated radiation therapy for early-stage oropharyngeal cancer (RTOG 00-22) Int J Radiat Oncol Biol Phys 76 2010 1333 1338
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 1333-1338
    • Eisbruch, E.1    Harris, J.2    Garden, A.S.3
  • 33
    • 79960367969 scopus 로고    scopus 로고
    • The influence of HPV-associated p16-expression on accelerated fractionated radiotherapy in head and neck cancer: Evaluation of the randomised DAHANCA 6&7 trial
    • P. Lassen, J.G. Eriksen, and A. Krogdahl The influence of HPV-associated p16-expression on accelerated fractionated radiotherapy in head and neck cancer: evaluation of the randomised DAHANCA 6&7 trial Radiother Oncol 100 2011 49 55
    • (2011) Radiother Oncol , vol.100 , pp. 49-55
    • Lassen, P.1    Eriksen, J.G.2    Krogdahl, A.3
  • 34
    • 80054081483 scopus 로고    scopus 로고
    • Maximum tolerated dose in a phase i trial on adaptive dose painting by numbers for head and neck cancer
    • I. Madani, F. Duprez, and T. Boterberg Maximum tolerated dose in a phase I trial on adaptive dose painting by numbers for head and neck cancer Radiother Oncol 101 2011 351 355
    • (2011) Radiother Oncol , vol.101 , pp. 351-355
    • Madani, I.1    Duprez, F.2    Boterberg, T.3


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