Transcriptional regulation of episodic glucocorticoid secretion

Molecular and Cellular Endocrinology

Volumn 371, Issue 1-2, 2013, Pages 62-70

  Liu, Ying ^a   Smith, Lorna I ^a,b   Huang, Victoria ^a   Poon, Victoria ^a   Coello, Ana ^a   Olah, Mark ^a   Spiga, Francesca ^b   Lightman, Stafford L ^b   Aguilera, Greti ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

ACTH; Melanocortin receptor associated protein (MRAP); Melanocortin type 2 receptor (MC2R); Steroidogenic acute regulatory protein (StAR); Stress; Transcription

Indexed keywords

CORTICOTROPIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME P450; CYTOCHROME P450 11A; GLUCOCORTICOID; HETEROGENEOUS NUCLEAR RNA; MELANOCORTIN RECEPTOR ASSOCIATED PROTEIN; MESSENGER RNA; RECEPTOR PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

ACUTE STRESS; CORTICOSTEROID RELEASE; CORTICOTROPIN RELEASE; CYTOCHROME P450 11A GENE; FEEDBACK SYSTEM; GENE; HORMONE ACTION; HUMAN; INTRACELLULAR SIGNALING; MELANOCORTIN RECEPTOR ASSOCIATED PROTEIN GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REVIEW; STEROIDOGENESIS; STEROIDOGENIC ACUTE REGULATORY PROTEIN GENE; TRANSCRIPTION REGULATION; ULTRADIAN RHYTHM;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; PHOSPHOPROTEINS; RECEPTORS, MELANOCORTIN; STEROIDS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84876087277     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.10.011     Document Type: Review

References (59)

1. Aguilera G., Volpi S., Rabadan-Diehl C. Transcriptional and post-transcriptional mechanisms regulating the rat pituitary vasopressin V1b receptor gene. J. Mol. Endocrinol. 2003, 30:99-108.
2. Benson D.A., Karsch-Mizrachi I., Lipman D.J., Ostell J., Wheeler D.L. GenBank. Nucleic Acids Res. 2005, 33:D34-D38.
3. Bush I.E. Species differences in adrenocortical secretion. J. Endocrinol. 1953, 9:95-NP.
4. Carnes M., Lent S., Feyzi J., Hazel D. Plasma adrenocorticotropic hormone in the rat demonstrates three different rhythms within 24 h. Neuroendocrinology 1989, 50:17-25.
5. Chaudhary L.R., Stocco D.M. Effect of different steroidogenic stimuli on protein phosphorylation and steroidogenesis in MA-10 mouse Leydig tumor cells. Biochim. Biophys. Acta 1991, 1094:175-184.
6. Christenson L.K., Johnson P.F., McAllister J.M., Strauss J.F. CCAAT/enhancer-binding proteins regulate expression of the human steroidogenic acute regulatory protein (StAR) gene. J. Biol. Chem. 1999, 274:26591-26598.
7. Churchill P.F., Kimura T. Topological studies of cytochromes P-450scc and P-45011 beta in bovine adrenocortical inner mitochondrial membranes. Effects of controlled tryptic digestion. J. Biol. Chem. 1979, 254:10443-10448.
8. Cone R.D., Mountjoy K.G., Robbins L.S., Nadeau J.H., Johnson K.R., Roselli-Rehfuss L., Mortrud M.T. Cloning and functional characterization of a family of receptors for the melanotropic peptides. Ann. N. Y. Acad. Sci. 1993, 680:342-363.
9. Conkright M.D., Canettieri G., Screaton R., Guzman E., Miraglia L., Hogenesch J.B., Montminy M. TORCs: transducers of regulated CREB activity. Mol. Cell 2003, 12:413-423.
10. Cudd T.A., LeBlanc M., Silver M., Norman W., Madison J., Keller-Wood M., Wood C.E. Ontogeny and ultradian rhythms of adrenocorticotropin and cortisol in the late-gestation fetal horse. J. Endocrinol. 1995, 144:271-283.
11. Dallman M.F., Akana S.F., Levin N., Walker C.D., Bradbury M.J., Suemaru S., Scribner K.S. Corticosteroids and the control of function in the hypothalamo-pituitary-adrenal (HPA) axis. Ann. N. Y. Acad. Sci. 1994, 746:22-31.
12. Della Fazia M.A., Servillo G., Foulkes N.S., Sassone-Corsi P. Stress-induced expression of transcriptional repressor ICER in the adrenal gland. FEBS Lett. 1998, 434:33-36.
13. Desir D., van Cauter E., Golstein J., Fang V.S., Leclercq R., Refetoff S., Copinschi G. Circadian and ultradian variations of ACTH and cortisol secretion. Horm. Res. 1980, 13:302-316.
14. Engler D., Pham T., Fullerton M.J., Clarke I.J., Funder J.W. Evidence for an ultradian secretion of adrenocorticotropin, beta-endorphin and alpha-melanocyte-stimulating hormone by the ovine anterior and intermediate pituitary. Neuroendocrinology 1989, 49:349-360.
15. Ferguson J.J. Protein synthesis and adrenocorticotropin responsiveness. J. Biol. Chem. 1963, 238:2754-2759.
16. Foulkes N.S., Borrelli E., Sassone-Corsi P. CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell 1991, 64:739-749.
17. Fremeau R.T., Lundblad J.R., Pritchett D.B., Wilcox J.N., Roberts J.L. Regulation of pro-opiomelanocortin gene transcription in individual cell nuclei. Science 1986, 234:1265-1269.
18. Gallagher T.F., Yoshida K., Roffwarg H.D., Fukushima D.K., Weitzman E.D., Hellman L. ACTH and cortisol secretory patterns in man. J. Clin. Endocrinol. Metab. 1973, 36:1058-1068.
19. Garren L.D., Ney R.L., Davis W.W. Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo. Proc. Natl. Acad. Sci. USA 1965, 53:1443-1450.
20. Hum D.W., Miller W.L. Transcriptional regulation of human genes for steroidogenic enzymes. Clin. Chem. 1993, 39:333-340.
21. Ivell R., Tillmann G., Wang H., Nicol M., Stewart P.M., Bartlick B., Walther N., Mason J.I., Morley S.D. Acute regulation of the bovine gene for the steroidogenic acute regulatory protein in ovarian theca and adrenocortical cells. J. Mol. Endocrinol. 2000, 24:109-118.
22. Iourgenko V., Zhang W., Mickanin C., Daly I., Jiang C., Hexham J.M., Orth A.P., Miraglia L., Meltzer J., Garza D., Chirn G.W., McWhinnie E., Cohen D., Skelton J., Terry R., Yu Y., Bodian D., Buxton F.P., Zhu J., Song C., Labow M.A. Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc. Natl. Acad. Sci. USA 2003, 100:12147-12152.
23. Kanyo R., Price D.M., Chik C.L., Ho A.K. Salt-inducible kinase 1 in the rat pinealocyte: adrenergic regulation and role in arylalkylamine N-acetyltransferase gene transcription. Endocrinology 2009, 150:4221-4230.
24. Katoh Y., Takemori H., Min L., Muraoka M., Doi J., Horike N., Okamoto M. Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm. Eur. J. Biochem. 2004, 271:4307-4319.
25. Keenan D.M., Roelfsema F., Veldhuis J.D. Endogenous ACTH concentration-dependent drive of pulsatile cortisol secretion in the human. Am. J. Physiol. Endocrinol. Metab. 2004, 287:E652-E661.
26. Keenan D.M., Alexander S., Irvine C., Veldhuis J.D. Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse. Endocrinology 2009, 150:1941-1951.
27. Lehoux J.G., Fleury A., Ducharme L. The acute and chronic effects of adrenocorticotropin on the levels of messenger ribonucleic acid and protein of steroidogenic enzymes in rat adrenal in vivo. Endocrinology 1998, 139:3913-3922.
28. Lightman S.L., Wiles C.C., Atkinson H.C., Henley D.E., Russell G.M., Leendertz J.A., McKenna M.A., Spiga F., Wood S.A., Conway-Campbell B.L. The significance of glucocorticoid pulsatility. Eur. J. Pharmacol. 2008, 583:255-262.
29. Lin X., Takemori H., Katoh Y., Doi J., Horike N., Makino A., Nonaka Y., Okamoto M. Salt-inducible kinase is involved in the ACTH/cAMP-dependent protein kinase signaling in Y1 mouse adrenocortical tumor cells. Mol. Endocrinol. 2001, 15:1264-1276.
30. Liu Y., Kalintchenko N., Sassone-Corsi P., Aguilera G. Inhibition of corticotrophin-releasing hormone transcription by inducible cAMP-early repressor in the hypothalamic cell line, 4B. J. Neuroendocrinol. 2006, 18:42-49.
31. Liu Y., Kamitakahara A., Kim A.J., Aguilera G. Cyclic adenosine 3',5'-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription. Endocrinology 2008, 149:3512-3520.
32. Liu Y., Coello A.G., Grinevich V., Aguilera G. Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription. Endocrinology 2010, 151:1109-1118.
33. Liu Y., Poon V., Sanchez-Watts G., Watts A.G., Takemori H., Aguilera G. Salt-inducible kinase is involved in the regulation of corticotropin-releasing hormone transcription in hypothalamic neurons in rats. Endocrinology 2012, 153:223-233.
34. Manna P.R., Dyson M.T., Eubank D.W., Clark B.J., Lalli E., Sassone-Corsi P., Zeleznik A.J., Stocco D.M. Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family. Mol. Endocrinol. 2002, 16:184-199.
35. Manna P.R., Stocco D.M. Crosstalk of CREB and Fos/Jun on a single cis-element: transcriptional repression of the steroidogenic acute regulatory protein gene. J. Mol. Endocrinol. 2007, 39:261-277.
36. McEwen B.S. Protective and damaging effects of stress mediators. N. Engl. J. Med. 1998, 338:171-179.
37. Metherell L.A., Chapple J.P., Cooray S., David A., Becker C., Ruschendorf F., Naville D., Begeot M., Khoo B., Nurnberg P., Huebner A., Cheetham M.E., Clark A.J. Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2. Nat. Genet. 2005, 37:166-170.
38. Mikami K., Strott C.A. Cyclic AMP-dependent protein kinase activity and protein phosphorylation in zones of the adrenal cortex. Biochem. Biophys. Res. Commun. 1986, 138:895-901.
39. Miller W.L., Strauss J.F. Molecular pathology and mechanism of action of the steroidogenic acute regulatory protein. StAR. J. Steroid. Biochem. Mol. Biol. 1999, 69:131-141.
40. Molina C.A., Foulkes N.S., Lalli E., Sassone-Corsi P. Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell 1993, 75:875-886.
41. Mountjoy K., Robbins L., Mortrud M., Cone R. The cloning of a family of genes that encode the melanocortin receptors. Science 1992, 257:1248-1251.
42. Munck A., Guyre P.M., Holbrook N.J. Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr. Rev. 1984, 5:25-44.
43. Munck A., Naray-Fejes-Toth A. Glucocorticoids and stress: permissive and suppressive actions. Ann. N. Y. Acad. Sci. 1994, 746:115-130.
44. Pon L.A., Hartigan J.A., Orme-Johnson N.R. Acute ACTH regulation of adrenal corticosteroid biosynthesis. Rapid accumulation of a phosphoprotein. J. Biol. Chem. 1986, 261:13309-13316.
45. Rabadan-Diehl C., Lolait S.J., Aguilera G. Regulation of pituitary vasopressin V1b receptor mRNA during stress in the rat. J. Neuroendocrinol. 1995, 7:903-910.
46. Rabadan-Diehl C., Kiss A., Camacho C., Aguilera G. Regulation of messenger ribonucleic acid for corticotropin releasing hormone receptor in the pituitary during stress. Endocrinology 1996, 137:3808-3814.
47. Roy S., Roy S.J., Pinard S., Taillefer L.D., Rached M., Parent J.L., Gallo-Payet N. Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids. Mol. Endocrinol. 2011, 25:1961-1977.
48. Sarabdjitsingh R.A., Conway-Campbell B.L., Leggett J.D., Waite E.J., Meijer O.C., de Kloet E.R., Lightman S.L. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner. Endocrinology 2010, 151:5369-5379.
49. Sewer M.B., Waterman M.R. ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex. Microsc. Res. Tech. 2003, 61:300-307.
50. Shepard J.D., Liu Y., Sassone-Corsi P., Aguilera G. Role of glucocorticoids and cAMP-mediated repression in limiting corticotropin-releasing hormone transcription during stress. J. Neurosci. 2005, 25:4073-4081.
51. Spiga F., Liu Y., Aguilera G., Lightman S.L. Temporal effect of adrenocorticotrophic hormone on adrenal glucocorticoid steroidogenesis: involvement of the transducer of regulated cyclic AMP-response element-binding protein activity. J. Neuroendocrinol. 2011, 23:136-142.
52. Spiga F., Waite E.J., Liu Y., Kershaw Y.M., Aguilera G., Lightman S.L. ACTH-dependent ultradian rhythm of corticosterone secretion. Endocrinology 2011, 152:1448-1457.
53. Stavreva D.A., Wiench M., John S., Conway-Campbell B.L., McKenna M.A., Pooley J.R., Johnson T.A., Voss T.C., Lightman S.L., Hager G.L. Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. Nat. Cell Biol. 2009, 11:1093-1102.
54. Stocco D.M., Clark B.J. Role of the steroidogenic acute regulatory protein (StAR) in steroidogenesis. Biochem. Pharmacol. 1996, 51:197-205.
55. Takemori H., Kanematsu M., Kajimura J., Hatano O., Katoh Y., Lin X.Z., Min L., Yamazaki T., Doi J., Okamoto M. Dephosphorylation of TORC initiates expression of the StAR gene. Mol. Cell. Endocrinol. 2007, 265-266:196-204.
56. Takemori H., Okamoto M. Regulation of CREB-mediated gene expression by salt inducible kinase. J. Steroid Biochem. Mol. Biol. 2008, 108:287-291.
57. Vale W., Spiess J., Rivier C., Rivier J. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 1981, 213:1394-1397.
58. Weitzman E.D., Fukushima D., Nogeire C., Roffwarg H., Gallagher T.F., Hellman L. Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. J. Clin. Endocrinol. Metab. 1971, 33:14-22.
59. Young W.S., Mezey E., Siegel R.E. Vasopressin and oxytocin mRNAs in adrenalectomized and Brattleboro rats: analysis by quantitative in situ hybridization histochemistry. Brain Res. 1986, 387:231-241.