Salt-inducible kinase is involved in the regulation of corticotropin- releasing hormone transcription in hypothalamic neurons in rats

Endocrinology

Volumn 153, Issue 1, 2012, Pages 223-233

  Liu, Ying ^a   Poon, Victoria ^a   Sanchez Watts, Graciela ^b   Watts, Alan G ^b   Takemori, Hiroshi ^c   Aguilera, Greti ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; FORSKOLIN; LUCIFERASE; MESSENGER RNA; PHOSPHOTRANSFERASE; SALT INDUCIBLE KINASE; SALT INDUCIBLE KINASE 1; SALT INDUCIBLE KINASE 2; SHORT HAIRPIN RNA; STAUROSPORINE; TRANSDUCER CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CORTICOTROPIN-RELEASING HORMONE; DNA PRIMERS; FORSKOLIN; GENE KNOCKDOWN TECHNIQUES; IN SITU HYBRIDIZATION; MALE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; RNA, SMALL INTERFERING; STAUROSPORINE; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84455191491     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1404     Document Type: Article

References (36)

1. Bale TL, Vale WW 2004 CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol 44: 525-557 (Pubitemid 38263852)
2. Vale W, Rivier C, Brown MR, Spiess J, Koob G, Swanson L, Bilezikjian L, Bloom F, Rivier J 1983 Chemical and biological characterization of corticotropin releasing factor. Recent ProgHormRes 39:245-270
3. Berrettini WH, Oxenstierna G, Sedvall Gr, Nurnberger JI Jr, Gold PW, Rubinow DR, Goldin LR 1988 Characteristics of cerebrospinal fluid neuropeptides relevant to clinical research. Psychiatry Res 25: 349-359
4. Heuser I, Bissette G, Dettling M, Schweiger U, Gotthardt U, Schmider J, Lammers CH, Nemeroff CB, Holsboer F 1998 Cerebrospinal fluid concentrations of corticotropin-releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: response to amitriptyline treatment. Depress Anxiety 8:71-79 (Pubitemid 28458051)
5. Holsboer F, Ising M 2008 Central CRH system in depression and anxiety-evidence from clinical studies with CRH1 receptor antagonists. Eur J Pharmacol 583:350-357
6. Nemeroff CB, Bissette G, Akil H, Fink M 1991 Neuropeptide concentrations in the cerebrospinal fluid of depressed patients treated with electroconvulsive therapy. Corticotrophin-releasing factor, β-endorphin and somatostatin. Br J Psychiatry 158:59-63
7. Watts AG, Sanchez-Watts G 2002 Interactions between heterotypic stressors and corticosterone reveal integrative mechanisms for controlling corticotropin-releasing hormone gene expression in the rat paraventricular nucleus. J Neurosci 22:6282-6289 (Pubitemid 35387669)
8. Guardiola-Diaz HM, Boswell C, Seasholtz AF 1994 The cAMPresponsive element in the corticotropin-releasing hormone gene mediates transcriptional regulation by depolarization. J BiolChem269: 14784-14791 (Pubitemid 24194046)
9. King BR, Nicholson RC 2007 Advances in understanding corticotrophin- releasing hormone gene expression. Front Biosci 12:581-590 (Pubitemid 46852808)
10. Liu Y, Kamitakahara A, Kim AJ, Aguilera G 2008 Cyclic adenosine 3′,5′-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription. Endocrinology 149:3512-3520 (Pubitemid 351919576)
11. Nikodemova M, Kasckow J, Liu H, Manganiello V, Aguilera G 2003 Cyclic adenosine 3′,5′-monophosphate regulation of corticotropin-releasing hormone promoter activity in AtT-20 cells and in a transformed hypothalamic cell line. Endocrinology 144:1292-1300 (Pubitemid 36428471)
12. Wölfl S, Martinez C, Majzoub JA 1999 Inducible binding of cyclic adenosine 3′,5′-monophosphate (cAMP)-responsive element binding protein (CREB) to a cAMP-responsive promoter in vivo. Mol Endocrinol 13:659-669 (Pubitemid 30645320)
13. Liu Y, Knobloch HS, Grinevich V, Aguilera G 2011 Stress induces nuclear translocation of the CREB co-activator, transducer of regulated CREB activity (TORC) in corticotropin releasing hormone neurons. J Neuroendocrinol 23:216-223
14. Liu Y, Coello AG, Grinevich V, Aguilera G 2010 Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription. Endocrinology 151:1109-1118
15. Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M 2003 TORCs:transducers of regulated CREB activity. Mol Cell 12:413-423
16. Takemori H, Kajimura J, Okamoto M 2007 TORC-SIK cascade regulates CREB activity through the basic leucine zipper domain. FEBS J 274:3202-3209 (Pubitemid 47024984)
17. Takemori H, Okamoto M 2008 Regulation of CREB-mediated gene expression by salt inducible kinase. J Steroid Biochem Mol Biol 108:287-291 (Pubitemid 351179638)
18. Bittinger MA, McWhinnie E, Meltzer J, Iourgenko V, Latario B, Liu X, Chen CH, Song C, Garza D, Labow M 2004 Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins. Curr Biol 14:2156-2161 (Pubitemid 39623199)
19. Wang Z, Takemori H, Halder SK, Nonaka Y, Okamoto M 1999 Cloning of a novel kinase (SIK) of theSNF1/AMPKfamily from high salt diet-treated rat adrenal. FEBS Lett 453:135-139 (Pubitemid 29335487)
20. Katoh Y, Takemori H, Horike N, Doi J, Muraoka M, Min L, Okamoto M 2004 Salt-inducible kinase (SIK) isoforms: their involvement in steroidogenesis and adipogenesis. Mol Cell Endocrinol 217: 109-112 (Pubitemid 38596635)
21. Katoh Y, Takemori H, Min L, Muraoka M, Doi J, Horike N, Okamoto M 2004 Salt-inducible kinase-1 represses cAMP response element- binding protein activity both in the nucleus and in the cytoplasm. Eur J Biochem 271:4307-4319 (Pubitemid 39506760)
22. Watts AG, Tanimura S, Sanchez-Watts G 2004 Corticotropin-releasing hormone and arginine vasopressin gene transcription in the hypothalamic paraventricular nucleus of unstressed rats: daily rhythms and their interactions with corticosterone. Endocrinology 145:529-540 (Pubitemid 38183794)
23. Wang B, Goode J, Best J, Meltzer J, Schilman PE, Chen J, Garza D, Thomas JB, Montminy M 2008 The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metab 7:434-444 (Pubitemid 351598021)
24. Katoh Y, Takemori H, Lin XZ, Tamura M, Muraoka M, Satoh T, Tsuchiya Y, Min L, Doi J, Miyauchi A, Witters LA, Nakamura H, Okamoto M 2006 Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade. FEBS J 273:2730-2748
25. Kanyo R, Price DM, Chik CL, Ho AK 2009 Salt-Inducible kinase 1 in the rat pinealocyte: adrenergic regulation and role in arylalkylamine N-acetyltransferase gene transcription. Endocrinology 150: 4221-4230
26. Liu Y, Watts AG, Sanchez-Watts G, Aguilera G Stimulus- and brain region-specific regulation of salt inducible kinase and AMP activated protein kinase in the rat hypothalamus. Society for Neuroscience Annual Meeting, San Diego, CA, 2010, Abstract 792.1
27. Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M 2005 The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437:1109-1111
28. Kageyama K, Suda T 2009 Regulatory mechanisms underlying corticotropin- releasing factor gene expression in the hypothalamus. Endocr J 56:335-344
29. Liu Y, Aguilera G 2009 Cyclic AMP inducible early repressor mediates the termination of corticotropin releasing hormone transcription in hypothalamic neurons. Cell Mol Neurobiol 29:1275-1281
30. Hashimoto YK, Satoh T, Okamoto M, Takemori H 2008 Importance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activity. J Cell Biochem 104: 1724-1739
31. Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA,UddL,Mäkelä TP, Hardie DG, Alessi DR 2004 LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J 23:833-843 (Pubitemid 38418750)
32. Bright NJ, Thornton C, Carling D 2009 The regulation and function of mammalian AMPK-related kinases. Acta Physiol (Oxf) 196: 15-26
33. Takemori H, Kanematsu M, Kajimura J, Hatano O, Katoh Y, Lin XZ, Min L, Yamazaki T, Doi J, Okamoto M 2007 Dephosphorylation of TORC initiates expression of the StAR gene. Mol Cell Endocrinol 265-266:196-204 (Pubitemid 46273966)
34. Rüegg UT, Burgess GM 1989 Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol Sci 10:218-220 (Pubitemid 19146392)
35. Yanagihara N, Tachikawa E, Izumi F, Yasugawa S, Yamamoto H, Miyamoto E 1991 Staurosporine: an effective inhibitor for Ca2+/ calmodulin-dependent protein kinase II. J Neurochem 56:294-298 (Pubitemid 21901963)
36. Liu Y, Randall WR, Schneider MF 2005 Activity-dependent and -independent nuclear fluxes of HDAC4 mediated by different kinases in adult skeletal muscle. J Cell Biol 168:887-897 (Pubitemid 40397003)