Copper surfaces reduce the rate of healthcare-acquired infections in the intensive care unit

Infection Control and Hospital Epidemiology

Volumn 34, Issue 5 SPL, 2013, Pages 479-486

  Salgado, Cassandra D ^a   Sepkowitz, Kent A ^b   John, Joseph F ^c   Robert Cantey, J ^a   Attaway, Hubert H ^a   Freeman, Katherine D ^d   Sharpe, Peter A ^e   Michels, Harold T ^f   Schmidt, Michael G ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^d Extrapolate LLC   (United States)

^e Irwin P Sharpe and Associates   (United States)

^f Pipe and Fittings   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER;

ADULT; AGED; ARTICLE; BACTERIAL COLONIZATION; CONTROLLED STUDY; ENVIRONMENT; FEMALE; HEALTHCARE ASSOCIATED INFECTION; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MORBIDITY; MORTALITY; NURSING; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ADULT; AGED; COLONY COUNT, MICROBIAL; COPPER; CROSS INFECTION; DISINFECTANTS; DISINFECTION; ENTEROCOCCUS; ENVIRONMENTAL MICROBIOLOGY; FEMALE; FOMITES; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; INCIDENCE; INTENSIVE CARE UNITS; INTENTION TO TREAT ANALYSIS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; PATIENTS' ROOMS; STAPHYLOCOCCAL INFECTIONS; VANCOMYCIN RESISTANCE;

EID: 84876083037     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/670207     Document Type: Article

References (36)

1. Klevens RM, Edwards JR, Richards CL, et al. Estimating health care-associated infections and deaths in U.S. hospitals, 2002. Public Health Rep 2007;122:160-166.
2. Scott RD. The Direct Medical Costs of Healthcare-Associated Infections in U.S. Hospitals and the Benefits of Prevention. Atlanta: Centers for Disease Control and Prevention, 2009.
3. Martin J. The Impact of Healthcare-Associated Infections in Pennsylvania. Harrisburg, PA: Pennsylvania Health Care Cost Containment Council, 2011. http://www.phc4.org. Accessed February 28, 2013.
4. Boyce JM. Environmental contamination makes an important contribution to hospital infection. J Hosp Infect 2007;65:50-54.
5. Blythe D, Keenlyside D, Dawson SJ, Galloway A. Environmental contamination due to methicillin-resistant Staphylococcus aureus (MRSA). J Hosp Infect 1998;38:67-69.
6. Duckro AN, Blom DW, Lyle EA, Weinstein RA, Hayden MK. Transfer of vancomycin-resistant enterococci via health care worker hands. Arch Intern Med 2005;165:302-307.
7. Hayden MK, Blom DW, Lyle EA, Moore CG, Weinstein RA. Risk of hand or glove contamination after contact with patients colonized with vancomycin-resistant Enterococcus or the colonized patients' environment. Infect Control Hosp Epidemiol 2008;29:149-154.
8. Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate surfaces? a systematic review. BMC Infect Dis 2006;6:130.
9. Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med 2006;166: 1945-1951.
10. Shaughnessy MK, Micielli RL, DePestel DD, et al. Evaluation of hospital room assignment and acquisition of Clostridium difficile infection. Infect Control Hosp Epidemiol 2011;32:201-206.
11. Huskins WC, Huckabee CM, O'Grady NP, et al. Intervention to reduce transmission of resistant bacteria in intensive care. N Engl J Med 2011;364:1407-1418.
12. RutalaWA, Weber DJ; Healthcare Infection Control Practices Advisory Committee. Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008. Atlanta: Centers for Disease Control and Prevention, 2008. http://www.cdc.gov/hicpac/Disinfection _Sterilization/acknowledg.html. Accessed February 28, 2013.
13. Otter JA, Yezli S, French GL. The role played by contaminated surfaces in the transmission of nosocomial pathogens. Infect Control Hosp Epidemiol 2011;32:687-699.
14. Otter JA, Puchowicz M, Ryan D, et al. Feasibility of routinely using hydrogen peroxide vapor to decontaminate rooms in a busy United States hospital. Infect Control Hosp Epidemiol 2009; 30:574-577.
15. Rutala WA, Gergen MF, Weber DJ. Room decontamination with UV radiation. Infect Control Hosp Epidemiol 2010;31:1025-1029.
16. US Environmental Protection Agency. EPA registers copper-containing alloy products. http://www.epa.gov/opp00001/factsheets /copper-alloy-products.htm. Published 2008. Accessed February 28, 2013.
17. Michels HT. Anti-microbial characteristics of copper. Stand News 2006;34:28-31.
18. Noyce JO, Michels H, Keevil CW. Potential use of copper surfaces to reduce survival of epidemic methicillin-resistant Staphylococcus aureus in the healthcare environment. J Hosp Infect 2006;63:289-297.
19. Warnes SL, Green SM, Michels HT, Keevil CW. Biocidal efficacy of copper alloys against pathogenic enterococci involves degradation of genomic and plasmid DNAs. Appl Environ Microbiol 2010;76:5390-5401.
20. Weaver L, Michels HT, Keevil CW. Survival of Clostridium difficile on copper and steel: futuristic options for hospital hygiene. J Hosp Infect 2008;68:145-151.
21. Weaver L, Noyce JO, Michels HT, Keevil CW. Potential action of copper surfaces on methicillin-resistant Staphylococcus aureus. J Appl Microbiol 2010;109:2200-2205.
22. Grass G, Rensing C, Solioz M. Metallic copper as an antimicrobial surface. Appl Environ Microbiol 2011;77:1541-1547.
23. Mehtar S, Wiid I, Todorov SD. The antimicrobial activity of copper and copper alloys against nosocomial pathogens and Mycobacterium tuberculosis isolated from healthcare facilities in theWestern Cape: an in-vitro study. J Hosp Infect 2008;68:45-51.
24. Marais F, Mehtar S, Chalkley L. Antimicrobial efficacy of copper touch surfaces in reducing environmental bioburden in a South African community healthcare facility. J Hosp Infect 2010;74: 80-82.
25. Schmidt MG, Attaway HH, Sharpe PA, et al. Sustained reduction of microbial burden on common hospital surfaces through the introduction of copper. J Clin Microbiol 2012;50(7):2217-2223.
26. Mikolay A, Huggett S, Tikana L, Grass G, Braun J, Nies DH. Survival of bacteria on metallic copper surfaces in a hospital trial. Appl Microbiol Biotechnol 2010;87:1875-1879.
27. Casey AL, Adams D, Karpanen TJ, et al. Role of copper in reducing hospital environment contamination. J Hosp Infect 2010;74:72-77.
28. Karpanen TJ, Casey AL, Lambert PA, et al. The antimicrobial efficacy of copper alloy furnishings in the clinical environment: a crossover study. Infect Control Hosp Epidemiol 2012;33:3-9.
29. Freitas EF, Harris RM, Blake RK, Salgado CD. Prevalence of USA300 community-acquired methicillin-resistant Staphylococcus aureus among patients with nasal colonization identified by active surveillance. Infect Control Hosp Epidemiol 2010;31:469-475.
30. Jain R, Kralovic SM, Evans ME, et al. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections. N Engl J Med 2011;364:1419-1430.
31. Olivier CA, Blake RK, Steed LL, Salgado CD. Risk of vancomycin-resistant Enterococcus (VRE) bloodstream infection among patients colonized with VRE. Infect Control Hosp Epidemiol 2008;29:404-409.
32. Sharpe PA, Schmidt MG. Control and mitigation of healthcareacquired infections: designing clinical trials to evaluate new materials and technologies. Herd 2011;5(1):94-115.
33. Schmidt MG, Anderson T, Attaway H, et al. Patient environment microbial burden reduction: a pilot study comparison of two terminal cleaning methods. Am J Infect Control 2012;40:559-561.
34. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309-332.
35. American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospitalacquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005;171:388-416.
36. Weber DJ, Rutala WA. Self-disinfecting surfaces. Infect Control Hosp Epidemiol 2012;33:10-13.