Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center

Journal of Clinical Oncology

Volumn 31, Issue 10, 2013, Pages 1336-1340

  Heald, Brandie ^a   Plesec, Thomas ^a   Liu, Xiuli ^a   Pai, Rish ^a   Patil, Deepa ^a   Moline, Jessica ^a   Sharp, Richard R ^a,b   Burke, Carol A ^a   Kalady, Matthew F ^a   Church, James ^a   Eng, Charis ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

AGED; ARTICLE; CANCER SCREENING; DNA METHYLATION; GENETIC ASSOCIATION; GENETIC COUNSELING; GENETIC VARIABILITY; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MUTATIONAL ANALYSIS; PEDIGREE ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; UNIVERSITY HOSPITAL;

ACADEMIC MEDICAL CENTERS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR; DNA-BINDING PROTEINS; GENETIC COUNSELING; HUMANS; IMMUNOHISTOCHEMISTRY; INTERDISCIPLINARY COMMUNICATION; MASS SCREENING; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; OHIO; PROTO-ONCOGENE PROTEINS B-RAF; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84876079162     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2012.45.1674     Document Type: Article

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