T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour

Immunology

Volumn 139, Issue 1, 2013, Pages 61-71

  Nuñez, Sarah ^a   Saez, Juan Jose ^a   Fernandez, Dominique ^a   Flores Santibañez, Felipe ^a   Alvarez, Karla ^a   Tejon, Gabriela ^a   Ruiz, Paulina ^a   Maldonado, Paula ^a   Hidalgo, Yessia ^a   Manriquez, Valeria ^a   Bono, Maria Rosa ^a   Rosemblatt, Mario ^a,b,c   Sauma, Daniela ^a,b  

^a UNIVERSITY OF CHILE   (Chile)

^b Fundacion Ciencia para la Vida   (Chile)

^c UNIVERSIDAD ANDRÉS BELLO   (Chile)

Author keywords

Anti tumour immunity; Ror t; T helper type 1 cells; T helper type 17 cells

Indexed keywords

GAMMA INTERFERON; RETINOID RELATED ORPHAN RECEPTOR GAMMA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CANCER INFILTRATION; CD4+ T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SUPPRESSOR CELL; TH1 CELL; TH17 CELL; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR MICROENVIRONMENT;

ANIMALS; CELL LINE, TUMOR; IMMUNE TOLERANCE; MICE; MICE, MUTANT STRAINS; NEOPLASMS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; TH1 CELLS; TH17 CELLS;

EID: 84876070070     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12055     Document Type: Article

References (39)

1. Kryczek I, Wei S, Zou L, Altuwaijri S, Szeliga W, Kolls J, Chang A, Zou W. Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment. J Immunol 2007; 178:6730-3.
2. Kryczek I, Banerjee M, Cheng P et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009; 114:1141-9.
3. + IL-17-producing T cells in ovarian cancer. Proc Natl Acad Sci USA 2008; 105:15505-10.
4. Su X, Ye J, Hsueh EC, Zhang Y, Hoft DF, Peng G. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol 2010; 184:1630-41.
5. Benchetrit F. Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism. Blood 2002; 99:2114-21.
6. Numasaki M, Fukushi J, Ono M et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood 2003; 101:2620-7.
7. Kryczek I, Wei S, Szeliga W, Vatan L, Zou W. Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 2009; 114:357-9.
8. Martin-Orozco N, Muranski P, Chung Y et al. T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 2009; 31:787-98.
9. Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009; 206:1457-64.
10. Muranski P, Boni A, Antony PA et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 2008; 112:362-73.
11. Gnerlich JL, Mitchem JB, Weir JS et al. Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer. J Immunol 2010; 185:4063-71.
12. Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010; 140:883-99.
13. Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162-74.
14. Bunt SK, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S. Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J Immunol 2006; 176:284-90.
15. Cheng P, Corzo CA, Luetteke N et al. Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med 2008; 205:2235-49.
16. Ghannam S, Pene J, Torcy-Moquet G, Jorgensen C, Yssel H. Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype. J Immunol 2010; 185:302-12.
17. Ouyang W, Kolls JK, Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 2008; 28:454-67.
18. 2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res 2007; 67:4507-13.
19. Sinha P, Okoro C, Foell D, Freeze HH, Ostrand-Rosenberg S, Srikrishna G. Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J Immunol 2008; 181:4666-75.
20. Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 cells. Annu Rev Immunol 2009; 27:485-517.
21. + immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 2006; 66:1123-31.
22. He D, Li H, Yusuf N, Elmets CA, Li J, Mountz JD, Xu H. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J Immunol 2010; 184:2281-8.
23. Yang Z, Zhang B, Li D, Lv M, Huang C, Shen GX, Huang B. Mast cells mobilize myeloid-derived suppressor cells and Treg cells in tumor microenvironment via IL-17 pathway in murine hepatocarcinoma model. PLoS ONE 2010; 5:e8922.
24. + T helper cells. Cell 2006; 126:1121-33.
25. Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR. An essential function for the nuclear receptor RORγ(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol 2004; 5:64-73.
26. Haile LA, Gamrekelashvili J, Manns MP, Korangy F, Greten TF. CD49d is a new marker for distinct myeloid-derived suppressor cell subpopulations in mice. J Immunol 2010; 185:203-10.
27. Numasaki M, Lotze MT, Sasaki H. Interleukin-17 augments tumor necrosis factor-α-induced elaboration of proangiogenic factors from fibroblasts. Immunol Lett 2004; 93:39-43.
28. Takahashi H, Numasaki M, Lotze MT, Sasaki H. Interleukin-17 enhances bFGF-, HGF- and VEGF-induced growth of vascular endothelial cells. Immunol Lett 2005; 98:189-93.
29. Honorati MC, Neri S, Cattini L, Facchini A. Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts. Osteoarthritis Cartilage 2006; 14:345-52.
30. Codarri L, Gyulveszi G, Tosevski V, Hesske L, Fontana A, Magnenat L, Suter T, Becher B. RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat Immunol 2011; 12:560-7.
31. H17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat Immunol 2011; 12:568-75.
32. H17 arsenal. Nat Immunol 2011; 12:521-2.
33. Kryczek I, Zhao E, Liu Y et al. Human TH17 cells are long-lived effector memory cells. Sci Transl Med 2011; 3:104ra0.
34. Muranski P, Borman ZA, Kerkar SP et al. Th17 cells are long lived and retain a stem cell-like molecular signature. Immunity 2011; 35:972-85.
35. Vignali DA, Collison LW, Workman CJ. How regulatory T cells work. Nat Rev Immunol 2008; 8:523-32.
36. Zhou Q, Munger ME, Highfill SL et al. Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia. Blood 2010; 116:2484-93.
37. Battaglia M, Roncarolo MG. The Tregs' world according to GARP. Eur J Immunol 2009; 39:3296-300.
38. Garcia-Hernandez Mde L, Hamada H, Reome JB, Misra SK, Tighe MP, Dutton RW. Adoptive transfer of tumor-specific Tc17 effector T cells controls the growth of B16 melanoma in mice. J Immunol 2010; 184:4215-27.
39. + T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 2007; 8:369-77.