메뉴 건너뛰기




Volumn 110, Issue 15, 2013, Pages 5903-5908

EJC core component MLN51 interacts with eIF3 and activates translation

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 3; MEMBRANE PROTEIN; METASTATIC LYMPH NODE 51 PROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84876055870     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1218732110     Document Type: Article
Times cited : (57)

References (40)
  • 1
    • 24644502657 scopus 로고    scopus 로고
    • From birth to death: The complex lives of eukaryotic mRNAs
    • Moore MJ (2005) From birth to death: The complex lives of eukaryotic mRNAs. Science 309(5740):1514-1518.
    • (2005) Science , vol.309 , Issue.5740 , pp. 1514-1518
    • Moore, M.J.1
  • 2
    • 60149110358 scopus 로고    scopus 로고
    • Pre-mRNA processing reaches back to transcription and ahead to translation
    • Moore MJ, Proudfoot NJ (2009) Pre-mRNA processing reaches back to transcription and ahead to translation. Cell 136(4):688-700.
    • (2009) Cell , vol.136 , Issue.4 , pp. 688-700
    • Moore, M.J.1    Proudfoot, N.J.2
  • 3
    • 0034193569 scopus 로고    scopus 로고
    • Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions
    • Le Hir H, Moore MJ, Maquat LE (2000) Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions. Genes Dev 14(9):1098-1108.
    • (2000) Genes Dev , vol.14 , Issue.9 , pp. 1098-1108
    • Le Hir, H.1    Moore, M.J.2    Maquat, L.E.3
  • 4
    • 2342540912 scopus 로고    scopus 로고
    • The ever-increasing complexities of the exon junction complex
    • Tange TO, Nott A, Moore MJ (2004) The ever-increasing complexities of the exon junction complex. Curr Opin Cell Biol 16(3):279-284.
    • (2004) Curr Opin Cell Biol , vol.16 , Issue.3 , pp. 279-284
    • Tange, T.O.1    Nott, A.2    Moore, M.J.3
  • 5
  • 6
    • 39149089317 scopus 로고    scopus 로고
    • Structural insights into the exon junction complex
    • Le Hir H, Andersen GR (2008) Structural insights into the exon junction complex. Curr Opin Struct Biol 18(1):112-119.
    • (2008) Curr Opin Struct Biol , vol.18 , Issue.1 , pp. 112-119
    • Le Hir, H.1    Andersen, G.R.2
  • 7
    • 4043118349 scopus 로고    scopus 로고
    • Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module
    • Degot S, et al. (2004) Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module. J Biol Chem 279(32):33702-33715.
    • (2004) J Biol Chem , vol.279 , Issue.32 , pp. 33702-33715
    • Degot, S.1
  • 8
    • 77957766928 scopus 로고    scopus 로고
    • The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila
    • Ashton-Beaucage D, et al. (2010) The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Cell 143(2):251-262.
    • (2010) Cell , vol.143 , Issue.2 , pp. 251-262
    • Ashton-Beaucage, D.1
  • 9
    • 77957792654 scopus 로고    scopus 로고
    • Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene
    • Roignant JY, Treisman JE (2010) Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Cell 143(2):238-250.
    • (2010) Cell , vol.143 , Issue.2 , pp. 238-250
    • Roignant, J.Y.1    Treisman, J.E.2
  • 10
    • 84857184337 scopus 로고    scopus 로고
    • Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators
    • Michelle L, et al. (2012) Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators. Mol Cell Biol 32(5):954-967.
    • (2012) Mol Cell Biol , vol.32 , Issue.5 , pp. 954-967
    • Michelle, L.1
  • 11
    • 60149086205 scopus 로고    scopus 로고
    • MRNA localization: Gene expression in the spatial dimension
    • Martin KC, Ephrussi A (2009) mRNA localization: Gene expression in the spatial dimension. Cell 136(4):719-730.
    • (2009) Cell , vol.136 , Issue.4 , pp. 719-730
    • Martin, K.C.1    Ephrussi, A.2
  • 12
    • 84867850145 scopus 로고    scopus 로고
    • NMD: A multifaceted response to premature translational termination
    • Kervestin S, Jacobson A (2012) NMD: A multifaceted response to premature translational termination. Nat Rev Mol Cell Biol 13(11):700-712.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.11 , pp. 700-712
    • Kervestin, S.1    Jacobson, A.2
  • 13
    • 41949135532 scopus 로고    scopus 로고
    • EJCs at the heart of translational control
    • Le Hir H, Séraphin B (2008) EJCs at the heart of translational control. Cell 133(2):213-216.
    • (2008) Cell , vol.133 , Issue.2 , pp. 213-216
    • Le Hir, H.1    Séraphin, B.2
  • 14
    • 0023503630 scopus 로고
    • Introns increase gene expression in cultured maize cells
    • Callis J, Fromm M, Walbot V (1987) Introns increase gene expression in cultured maize cells. Genes Dev 1(10):1183-1200.
    • (1987) Genes Dev , vol.1 , Issue.10 , pp. 1183-1200
    • Callis, J.1    Fromm, M.2    Walbot, V.3
  • 15
    • 0037406116 scopus 로고    scopus 로고
    • A quantitative analysis of intron effects on mammalian gene expression
    • Nott A, Meislin SH, Moore MJ (2003) A quantitative analysis of intron effects on mammalian gene expression. RNA 9(5):607-617.
    • (2003) RNA , vol.9 , Issue.5 , pp. 607-617
    • Nott, A.1    Meislin, S.H.2    Moore, M.J.3
  • 17
    • 0942268832 scopus 로고    scopus 로고
    • Splicing enhances translation in mammalian cells: An additional function of the exon junction complex
    • Nott A, Le Hir H, Moore MJ (2004) Splicing enhances translation in mammalian cells: An additional function of the exon junction complex. Genes Dev 18(2):210-222.
    • (2004) Genes Dev , vol.18 , Issue.2 , pp. 210-222
    • Nott, A.1    Le Hir, H.2    Moore, M.J.3
  • 18
    • 0141706348 scopus 로고    scopus 로고
    • Exon junction complexes mediate the enhancing effect of splicing on mRNA expression
    • Wiegand HL, Lu S, Cullen BR (2003) Exon junction complexes mediate the enhancing effect of splicing on mRNA expression. Proc Natl Acad Sci USA 100(20):11327-11332.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.20 , pp. 11327-11332
    • Wiegand, H.L.1    Lu, S.2    Cullen, B.R.3
  • 19
    • 28344456363 scopus 로고    scopus 로고
    • Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core
    • Tange TO, Shibuya T, Jurica MS, Moore MJ (2005) Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core. RNA 11(12):1869-1883.
    • (2005) RNA , vol.11 , Issue.12 , pp. 1869-1883
    • Tange, T.O.1    Shibuya, T.2    Jurica, M.S.3    Moore, M.J.4
  • 20
    • 41949101770 scopus 로고    scopus 로고
    • SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs
    • Ma XM, Yoon SO, Richardson CJ, Jülich K, Blenis J (2008) SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. Cell 133(2):303-313.
    • (2008) Cell , vol.133 , Issue.2 , pp. 303-313
    • Ma, X.M.1    Yoon, S.O.2    Richardson, C.J.3    Jülich, K.4    Blenis, J.5
  • 21
    • 84860378396 scopus 로고    scopus 로고
    • Perispeckles are major assembly sites for the exon junction core complex
    • Daguenet E, et al. (2012) Perispeckles are major assembly sites for the exon junction core complex. Mol Biol Cell 23(9):1765-1782.
    • (2012) Mol Biol Cell , vol.23 , Issue.9 , pp. 1765-1782
    • Daguenet, E.1
  • 22
    • 27144445082 scopus 로고    scopus 로고
    • The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity
    • Ballut L, et al. (2005) The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity. Nat Struct Mol Biol 12(10):861-869.
    • (2005) Nat Struct Mol Biol , vol.12 , Issue.10 , pp. 861-869
    • Ballut, L.1
  • 23
    • 33748924333 scopus 로고    scopus 로고
    • EIF3: A versatile scaffold for translation initiation complexes
    • Hinnebusch AG (2006) eIF3: A versatile scaffold for translation initiation complexes. Trends Biochem Sci 31(10):553-562.
    • (2006) Trends Biochem Sci , vol.31 , Issue.10 , pp. 553-562
    • Hinnebusch, A.G.1
  • 24
    • 41949113083 scopus 로고    scopus 로고
    • Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay
    • Isken O, et al. (2008) Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell 133(2):314-327.
    • (2008) Cell , vol.133 , Issue.2 , pp. 314-327
    • Isken, O.1
  • 25
    • 34548550361 scopus 로고    scopus 로고
    • The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly
    • Baguet A, et al. (2007) The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly. J Cell Sci 120(Pt 16):2774-2784.
    • (2007) J Cell Sci , vol.120 , Issue.PART 16 , pp. 2774-2784
    • Baguet, A.1
  • 26
    • 1542305510 scopus 로고    scopus 로고
    • The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro
    • Fraser CS, et al. (2004) The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro. J Biol Chem 279(10):8946-8956.
    • (2004) J Biol Chem , vol.279 , Issue.10 , pp. 8946-8956
    • Fraser, C.S.1
  • 27
    • 84861843696 scopus 로고    scopus 로고
    • A mechanistic overview of translation initiation in eukaryotes
    • Aitken CE, Lorsch JR (2012) A mechanistic overview of translation initiation in eukaryotes. Nat Struct Mol Biol 19(6):568-576.
    • (2012) Nat Struct Mol Biol , vol.19 , Issue.6 , pp. 568-576
    • Aitken, C.E.1    Lorsch, J.R.2
  • 28
    • 75149196287 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation and principles of its regulation
    • Jackson RJ, Hellen CU, Pestova TV (2010) The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol 11(2):113-127.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.2 , pp. 113-127
    • Jackson, R.J.1    Hellen, C.U.2    Pestova, T.V.3
  • 30
    • 17044409660 scopus 로고    scopus 로고
    • UAUG and uORFs in human and rodent 5'untranslated mRNAs
    • Iacono M, Mignone F, Pesole G (2005) uAUG and uORFs in human and rodent 5'untranslated mRNAs. Gene 349:97-105.
    • (2005) Gene , vol.349 , pp. 97-105
    • Iacono, M.1    Mignone, F.2    Pesole, G.3
  • 31
    • 79958276198 scopus 로고    scopus 로고
    • Translational control via protein-regulated upstream open reading frames
    • Medenbach J, Seiler M, Hentze MW (2011) Translational control via protein-regulated upstream open reading frames. Cell 145(6):902-913.
    • (2011) Cell , vol.145 , Issue.6 , pp. 902-913
    • Medenbach, J.1    Seiler, M.2    Hentze, M.W.3
  • 32
    • 51149091031 scopus 로고    scopus 로고
    • EIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA
    • Szamecz B, et al. (2008) eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA. Genes Dev 22(17):2414-2425.
    • (2008) Genes Dev , vol.22 , Issue.17 , pp. 2414-2425
    • Szamecz, B.1
  • 33
    • 77950243975 scopus 로고    scopus 로고
    • The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames
    • Roy B, et al. (2010) The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames. RNA 16(4):748-761.
    • (2010) RNA , vol.16 , Issue.4 , pp. 748-761
    • Roy, B.1
  • 34
    • 36849080874 scopus 로고    scopus 로고
    • The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation
    • Pöyry TA, Kaminski A, Connell EJ, Fraser CS, Jackson RJ (2007) The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation. Genes Dev 21(23):3149-3162.
    • (2007) Genes Dev , vol.21 , Issue.23 , pp. 3149-3162
    • Pöyry, T.A.1    Kaminski, A.2    Connell, E.J.3    Fraser, C.S.4    Jackson, R.J.5
  • 35
    • 84869087484 scopus 로고    scopus 로고
    • CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex
    • Saulière J, et al. (2012) CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex. Nat Struct Mol Biol 19(11):1124-1131.
    • (2012) Nat Struct Mol Biol , vol.19 , Issue.11 , pp. 1124-1131
    • Saulière, J.1
  • 36
    • 84869090905 scopus 로고    scopus 로고
    • The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus
    • Singh G, et al. (2012) The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. Cell 151(4):750-764.
    • (2012) Cell , vol.151 , Issue.4 , pp. 750-764
    • Singh, G.1
  • 37
    • 66249134562 scopus 로고    scopus 로고
    • The hierarchy of exonjunction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay
    • Gehring NH, Lamprinaki S, Hentze MW, Kulozik AE (2009) The hierarchy of exonjunction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay. PLoS Biol 7(5):e1000120.
    • (2009) PLoS Biol , vol.7 , Issue.5
    • Gehring, N.H.1    Lamprinaki, S.2    Hentze, M.W.3    Kulozik, A.E.4
  • 38
    • 0037182754 scopus 로고    scopus 로고
    • Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer
    • Degot S, et al. (2002) Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer. Oncogene 21(28):4422-4434.
    • (2002) Oncogene , vol.21 , Issue.28 , pp. 4422-4434
    • Degot, S.1
  • 39
    • 0029149178 scopus 로고
    • Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17
    • Tomasetto C, et al. (1995) Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. Genomics 28(3):367-376.
    • (1995) Genomics , vol.28 , Issue.3 , pp. 367-376
    • Tomasetto, C.1
  • 40
    • 84862300106 scopus 로고    scopus 로고
    • Versatility of RNA-binding proteins in cancer
    • Wurth L (2012) Versatility of RNA-Binding Proteins in Cancer. Comp Funct Genomics 2012:178525.
    • (2012) Comp Funct Genomics , vol.2012 , pp. 178525
    • Wurth, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.